scholarly journals Moscow newborns: a demand of primary dietary prophylaxis of allergy

2013 ◽  
Vol 10 (3) ◽  
pp. 24-29
Author(s):  
M S Geneva ◽  
A N Pampura
Keyword(s):  
Primary Prevention ◽  
Dietary Supplement ◽  
Allergic Diseases ◽  
Maternity Hospital ◽  
Close Relative ◽  
Milk Formula ◽  
Wide Range ◽  
Close Relatives ◽  
Allergic Manifestations ◽  
Prevention Of Allergy

Background. Primary prevention of allergic diseases in children is specified by the increase of allergic diseases prevalence in a population and may be mediated through the special milk formulas. The study aimed to evaluate the prevalence of allergic symptoms in families of Moscow newborns and to evaluate the hypothetic demand in a special milk formula dietary supplement. Methods. 18 visits to the Postnatal Department of Moscow No.1 Maternity Hospital were carried out. All women delivered in the preceding 48 hours were questioned on each visit. Information on relatives of a newborns family and on allergic manifestations in them has been obtained from the mothers. Information on 3534 relatives of 393 newborns was collected. Results. Moscow newborns-2011 cohort have allergy manifestations in one close relative within 41,7% families, in two or more relatives within 14,5% families. In case of all relatives studied the respective prevalence is 59% and 25,1%. Conclusion. Moscow newborns-2011 primary prevention of allergy (including special formula supplement) is probable in 14,5 % families in case of two or more close relatives with allergies and in 25% families in case two or more relatives with allergy within the wide range of them.

scholarly journals ALLERGIC DISEASES PRIMARY PREVENTION IN CHILDREN: POSITIVE PREDICTIVE VALUE AND HIGH SPECIFICITY OF INFORMATION ON ALLERGIC DISEASES IN MALE RELATIVES

2010 ◽  
Vol 7 (6) ◽  
pp. 34-37
Author(s):  
M S Treneva
Keyword(s):  
Primary Prevention ◽  
Positive Predictive Value ◽  
Allergic Disease ◽  
Predictive Value ◽  
High Specificity ◽  
Allergic Diseases ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Wide Range ◽  
Risk Criterion

Background. Сhildren allergic diseases primary prevention could be advanced with exploration of positive predictive value (PPV), negative predictive value (NPV), sensitivity (Se) and specificity (Sp) of information on allergic diseases in a wide range of relatives. Methods. retrospective analytic cross-sectional study. 1974 relatives of 212 children with allergic diseases and 137 controls were questioned. Couples of children equally aged were grouped in «×2»tables for each relativetype. Se was calculated as relative' allergic disease probability in child with allergic disease. Sp was calculated as negative allergic disease relative' probability in negative allergic disease children. PPV was calculated as a probability of allergic diseased children in positive allergic disease relatives; NPV -as a probability of negative allergic diseased children in negative allergic disease relatives. Results. PPV was of high quantity in male relatives -father' father (86%), male cousins (80%), mother' father (77%), mother' brother (73%), father of a child (72%). Mother' PPV was under 65%. Sp of all relatives was of good quantity. The top levels belong to male relatives -father' father (97%), fathermother (94%), father' brother (91%), male cousins (91%), mother' brother (89%). NPV of all relatives was useless for clinical practitioner. Se was low in all relatives. Mother' Se was on top with 67%. So, male relatives'allergic disease importance is confirmed by high PPV and high Sp in grandfathers, uncles, male cousins. Conclusion. high PPV and high Sp of information on allergic disease in male relatives combine prognostic valid and specific risk criterion for allergic diseases in children. A child should be set for a primary prevention of allergic disease in case of allergic disease in grandfathers, or uncles, or male cousins, or child' father.

Could the Substance Misuse of a Relative be an Important Factor for Those Seeking Help for Anxiety and Depression? A Preliminary Prevalence Study within Improving Access to Psychological Therapies (IAPT)

2016 ◽  
Vol 44 (6) ◽  
pp. 723-729 ◽  
Author(s):  
Elizabeth Newton ◽  
Nicola Shepherd ◽  
Jim Orford ◽  
Alex Copello
Keyword(s):  
Severe Depression ◽  
Routine Data ◽  
Research Area ◽  
Close Relative ◽  
Service Users ◽  
Depression And Anxiety ◽  
Psychological Therapies ◽  
Important Research Area ◽  
Close Relatives ◽  
Drug Problems

Background: The psychological difficulties and emotional impacts resulting from the substance use of close relatives constitute a large, underestimated and frequently unidentified health burden. The development of primary care mental health services in response to the Improving Access to Psychological Therapies initiative provides an opportunity to investigate this in more depth. Aims: A preliminary exploration of prevalence of IAPT service-users being treated for moderate-severe depression and/or anxiety who report that they have relatives with alcohol and/or drug problems. To explore the characteristics of the sample including comparison with those without a substance misusing relative. Method: One hundred service users completed a brief questionnaire. Routine data on depression and anxiety symptoms were accessed for the full consenting sample. Descriptive statistics were used to explore the family members of substance users and differences to the rest of the sample. Results: Twenty-two of the 100 IAPT service users reported having a close relative whose use of substances was of concern to them. The group with a relative who used substances were more depressed at the beginning of treatment than the rest of the sample. Conclusions: A significant number of people seeking psychological help for depression and anxiety within IAPT services reported being concerned about a close relative who misuses substances. They may be more distressed than those without a relative who misuses substances. Further exploration is warranted but preliminary findings indicate that this is an important research area with significant clinical implications.

scholarly journals Risk factors of adolescent health: mass poll results

2020 ◽  
Vol 65 (3) ◽  
pp. 91-99
Author(s):  
R. U. Khabriev ◽  
R. I. Yagudina ◽  
M. A. Rashid ◽  
E. E. Arinina
Keyword(s):  
Risk Factors ◽  
Healthy Lifestyle ◽  
The Body ◽  
Noncommunicable Disease ◽  
Disease Spread ◽  
Noncommunicable Diseases ◽  
Fresh Vegetables ◽  
Wide Range ◽  
Close Relatives ◽  
Public Health Epidemiology

Objective. To study the risk factors of noncommunicable disease spread in adolescents based on the mass pole results.Methods. The authors conducted four waves of study within the framework of the monitoring project “Risk factors for human health” in 2014–2017. The study included a multistage stratified territorial random sample of 1,691 patients over 11 years. The research population included 170 adolescents (11–19 years) (10%).Results. An adverse profile of risk factors for noncommunicable diseases was predetermined by: overweight in adolescents (10%), increased blood pressure (18%), unfavorable history of cardiovascular events in close relatives (60–70%), nutritional disorders (80–96%) , low level of physical activity (5%), smoking (20%), and alcohol consumption (26% of respondents). The body weight deficiency (35%) and overweight (10%), along with sufficient consumption of fresh vegetables and fruits in only 7% of cases reflects gross malnutrition of adolescents, which determines their future development. Awareness of adolescents of the main risk factors for noncommunicable diseases remains low (less than 30–40% for different factors). The example of close relatives, friends and stressful situations predetermine the emergence of bad habits (consumption of alcohol and tobacco) in adolescents.Scope of application. Pediatrics, public health, epidemiology.Conclusion. In order to correct adverse risk factors of noncommunicable diseases, it is necessary to attract a wide range of specialists, including intensive family and personal psychological consultations with adolescents. These measures will motivate adolescents to a healthy lifestyle and reduce the burden of noncommunicable diseases in the population of the Russian Federation.

Allergic disease

2019 ◽  
pp. 129-180
Author(s):  
Gavin Spickett
Keyword(s):  
Allergic Reaction ◽  
Allergic Disease ◽  
Allergic Diseases ◽  
Second World War ◽  
Differential Diagnoses ◽  
Atopic Diseases ◽  
World War ◽  
Wide Range ◽  
Second World

Allergic diseases are common: it has been estimated that 15% of the population will suffer from some sort of allergic reaction during their lifetime. There has been an increase in atopic diseases since the Second World War. This chapter discusses the presentation, immunological features, diagnosis, testing, and treatment for a wide range of allergic diseases. When appropriate, differential diagnoses are included.

scholarly journals Food Hypersensitivity as a Cause of Atopic Dermatitis

2018 ◽  
Vol 34 (5-6) ◽  
pp. 129-35
Author(s):  
Hendra Santoso
Keyword(s):  
Atopic Dermatitis ◽  
Skin Prick Test ◽  
Allergic Diseases ◽  
Food Hypersensitivity ◽  
Prick Test ◽  
Skin Symptoms ◽  
History Of ◽  
Nineteen 6 ◽  
Allergic Manifestations ◽  
Positive Results

Thirty children from infancy to 12 years suffering from atopic dermatitis were evaluated for food hypersensitivity by means of history, skin prick test, total eosinophils count, and elimination of suspected food. Sixteen (53%) patients had history of allergy to suspected food, the other 16 (53%) had ether allergic diseases. Of the 30 patients, 15 (50%) had one of the parents with allergic diseases, and in 3 patients both parents suffered from a1Iergic diseases. Nineteen (6:3-1.) children had atopic dermatitis triggered by food; egg accounted for 400/o, fish for 53-lo and shrimp for 40% for the allergic manifestations. Skin prick test consisted of 20 food allergens was done to all children above 2 years of age, 12 (40%) of the pa1ients showed positive results. This study demonstrated that food hypersensitivity may play a pathogenic role in some children with atopic dermatitis. Appropriate diagnosis and restriction of diet can improve their skin symptoms.

Experiences of a Recovery-Oriented Caring Approach to Suicidal Behavior: A Single-Case Study

2019 ◽  
Vol 29 (14) ◽  
pp. 2084-2095 ◽  
Author(s):  
Linda Sellin ◽  
Tomas Kumlin ◽  
Tuula Wallsten ◽  
Lena Wiklund Gustin
Keyword(s):  
Suicidal Behavior ◽  
Single Case ◽  
Suicidal Patient ◽  
Close Relative ◽  
Psychiatric Clinic ◽  
Single Case Study ◽  
Mental Health Nurses ◽  
Individual Care ◽  
Close Relatives

Research considering the basis for mental health nurses wanting to enable recovery among people who suffer from suicidal behavior is sparse. The aim of this study is to explore and evaluate how a new recovery-oriented caring approach (ROCA) was experienced by a suicidal patient in a context of close relatives and nurses. A single-case study with a qual-quan mixed-method design was chosen. Participants were recruited from a psychiatric clinic in Sweden and consisted of one patient, one close relative to the patient, and three nurses. The results reveal that the ROCA enabled the patient to narrate, bear experiences of hopelessness, and ask for support, rather than view suicide as the only possible solution. ROCA has the potential to support patients, relatives, and nurses to develop a common language, considering the patient’s life situation and struggles and to use this as a source for the patient’s individual care planning.

Cutting the cord: is birth already too late for primary prevention of allergy?

1997 ◽  
Vol 27 (1) ◽  
pp. 4-6 ◽  
Author(s):  
Mark A. Brown ◽  
Marilyn J. Halonen ◽  
Fernando D. Martinez
Keyword(s):  
Primary Prevention ◽  
Prevention Of Allergy

scholarly journals Effects of Linalyl Acetate on Thymic Stromal Lymphopoietin Production in Mast Cells

Molecules ◽  
2018 ◽  
Vol 23 (7) ◽  
pp. 1711 ◽  
Author(s):  
Phil-Dong Moon ◽  
Na-Ra Han ◽  
Jin Lee ◽  
Hyung-Min Kim ◽  
Hyun-Ja Jeong
Keyword(s):  
Intracellular Calcium ◽  
Inflammatory Diseases ◽  
Quantitative Polymerase Chain Reaction ◽  
Allergic Diseases ◽  
Nuclear Factor Κb ◽  
Thymic Stromal Lymphopoietin ◽  
Enzyme Linked Immunosorbent Assay ◽  
Linalyl Acetate ◽  
Caspase 1 ◽  
Wide Range

Thymic stromal lymphopoietin (TSLP) is an important factor responsible for the pathogenesis of allergic diseases, such as atopic dermatitis and asthma. Because linalyl acetate (LA) possesses a wide range of pharmacological properties, being antispasmodic, anti-inflammatory, and anti-hyperpigmentation, we hypothesized that LA could inhibit TSLP. Therefore, enzyme-linked immunosorbent assay, quantitative polymerase chain reaction, caspase-1 assay, Western blot analysis, fluorescent analyses of the intracellular calcium levels, and the phorbol myristate acetate (PMA)-induced edema model were used to investigate how LA inhibits the production of TSLP in HMC-1 cells. LA reduced the production and mRNA expression of TSLP in HMC-1 cells. LA also inhibited the activation of nuclear factor-κB and degradation of IκBα. PMA plus A23187 stimulation up-regulated caspase-1 activity in HMC-1 cells; however, this up-regulated caspase-1 activity was down-regulated by LA. Finally, LA decreased intracellular calcium levels in HMC-1 cells as well as PMA-induced ear swelling responses in mice. Taken together, these results suggest that LA would be beneficial to treatment of atopic and inflammatory diseases by reducing TSLP.

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