scholarly journals Chest CT findings in COVID-19

2021 ◽  
Vol 3 (2) ◽  
pp. 1-5
Author(s):  
Radosław Serek ◽  
Małgorzata Serek
Keyword(s):  
Diffuse Alveolar Damage ◽  
High Specificity ◽  
Chest Ct ◽  
Wall Thickening ◽  
Vascular Pattern ◽  
Rt Pcr ◽  
Bronchial Wall ◽  
Severity Of The Disease ◽  
Reactive Hyperplasia ◽  
Interlobular Septal Thickening

RT-PCR is the gold standard in the diagnosis of COVID-19 infections, due to its high specificity. However, there are clinical situations in which chest CT may prove vital, for example in patients with high clinical and epidemiologic suspicion towards COVID-19 before positive RT-PCR conversion or in detecting complications. Researchers have developed scales that, based on the findings in chest CT, help predict the severity of the disease. There are three main pathologic patterns of lung injury that correlate with the duration of COVID-19 symptoms. Epithelial pattern with diffuse alveolar damage and desquamation/reactive hyperplasia of pneumocytes; vascular pattern with capillary congestion and (micro)thrombi and fibrotic pattern with interstitial fibrous changes. The epithelial pattern and vascular pattern appear early, even before the symptoms of the disease, whereas the fibrous pattern appears approximately three weeks after the onset of the disease. Typical findings on chest CT in COVID-19 infection are: GGO, consolidation, GGO mixed with consolidation, interlobular septal thickening, air bronchogram sign, crazy paving, bronchial wall thickening and vascular enlargement. Findings that may suggest a different etiology include multiple nodules, tree-in-bud opacities, bronchiectasis, pleural and pericardial effusion, extensive consolidations.

scholarly journals The Chest CT Features of Coronavirus Disease 2019 (COVID-19) in China: A Meta-analysis of 19 Trials

2020 ◽  
Author(s):  
Haitao Yang ◽  
Yuzhu Lan ◽  
Xiujuan Yao ◽  
Sheng Lin ◽  
Baosong Xie
Keyword(s):  
Meta Analysis ◽  
Ct Imaging ◽  
Chest Ct ◽  
Chinese Patients ◽  
Wall Thickening ◽  
Bronchial Wall ◽  
Random Effects Models ◽  
Lymph Node Enlargement ◽  
Mean Differences ◽  
Interlobular Septal Thickening

AbstractObjectiveThis study aimed to summarize the characteristics of chest CT imaging in Chinese patients with Coronavirus Disease 2019 (COVID-19) to provide reliable evidence for further guiding clinical routine.MethodsPubMed, Embase and Web of Science databases were thoroughly searched to identified relevant articles involving the features of chest CT imaging in Chinese patients with COVID-19. All data were analyzed utilizing R software version i386 4.0.0. Random-effects models were employed to calculate pooled mean differences.Results19 trials incorporating 1332 cases were included in the study. The results demonstrated that the incidence of ground-glass opacities (GGO) was 0.79, consolidation was 0.34; mixed GGO and consolidation was 0.46; air bronchogram sign was 0.41; crazy paving pattern was 0.32; interlobular septal thickening was 0.55; reticulation was 0.30; bronchial wall thickening was 0.24; vascular enlargement was 0.74. subpleural linear opacity was 0.28; intrathoracic lymph node enlargement was 0.03; pleural effusions was 0.03. The distribution in lung: the incidence of central was 0.05; peripheral was 0.74; peripheral involving central was 0.38; diffuse was 0.19; unifocal involvement was 0.09; multifocal involvement was 0.57; unilateral was 0.16; bilateral was 0.83; The incidence of lobes involved (>2) was 0.70; lobes involved (≦2) was 0.35.ConclusionGGO, vascular enlargement, interlobular septal thickening more frequently occurred in patients with COVID-19. Peripheral, bilateral, involved lobes >2 might be the features of COVID-19 in the distribution aspect. Therefore, based on the aboved features of COVID-19 in chest CT imaging, it might be a promising means for identifying COVID-19.

scholarly journals Early chest computed tomography to diagnose COVID-19 from suspected patients: A multicenter retrospective study

2020 ◽  
Author(s):  
Congliang Miao ◽  
Mengdi Jin ◽  
Li Miao ◽  
Xinying Yang ◽  
Peng Huang ◽  
...  
Keyword(s):  
Ground Glass Opacity ◽  
High Specificity ◽  
Diagnostic Value ◽  
Chest Ct ◽  
Imaging Features ◽  
Rt Pcr ◽  
Polymerase Chain ◽  
Low Sensitivity ◽  
Chest Ct Scan ◽  
Ct Features

AbstractObjectiveThe purpose of this study is to distinguish the imaging features of COVID-19 with other chest infectious diseases and evaluate diagnostic value of chest CT for suspected patients.MethodsAdult suspected patients aged>18 years within 14 days who underwent chest CT scan and reverse-transcription polymerase-chain-reaction (RT-PCR) tests were enrolled. The enrolled patients were confirmed and grouped according to results of RT-PCR tests. The data of basic demographics, single chest CT features, and combined chest CT features were analyzed for confirmed and non-confirmed groups.ResultsA total of 130 patients were enrolled with 54 cases positive and 76 cases negative. The typical CT imaging features of positive group were ground glass opacity (GGO), crazy-paving pattern and air bronchogram. The lesions were mostly distributed bilaterally, close to the lower lungs or the pleura. When features combined, GGO with bilateral pulmonary distribution and GGO with pleural distribution were more common, of which were 31 cases (57.4%) and 30 cases (55.6%) respectively. The combinations were almost presented statistically significant (P<0.05) except for the combination of GGO with consolidation. Most combinations presented relatively low sensitivity but extremely high specificity. The average specificity of these combinations is around 90%.ConclusionsThe combinations of GGO could be useful in the identification and differential diagnosis of COVID-19, which alerts clinicians to isolate patients for treatment promptly and repeat RT-PCR tests until incubation ends.

scholarly journals CT findings of patients infected with SARS-CoV-2

2020 ◽  
Author(s):  
Xiaoyang Wang ◽  
Chenbin Liu ◽  
Liang Hong ◽  
Cuiyun Yuan ◽  
Jiguang Ding ◽  
...  
Keyword(s):  
Wall Thickening ◽  
Bronchial Wall ◽  
Pleural Thickening ◽  
Ct Findings ◽  
Lymph Node Enlargement ◽  
Peripheral Area ◽  
Reversed Halo Sign ◽  
The Common ◽  
Single Lesion ◽  
Interlobular Septal Thickening

Abstract Objective: we aimed to describe the chest CT findings in sixty-seven patientsinfected by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Method and material: We retrospectively reviewed 67 patients hospitalized in Ruian People's Hospital. All the patients received the positive diagnosis of SARS-CoV-2 infection. The CT and clinical data were collected between January, 23 and February, 10, 2020. The CT images were analyzed by the radiologists.Conclusion: There are 54 patients with positive CT findings and 13 patients with negative CT findings. The common CT findings in hospitalized patients with SARS-CoV-2 infection were ground glass opacities (42/54), lesions located in the peripheral area (50/54), multiple lesions(46/54), and lesions located in the lower lobes (42/54). There were some less common CT findings: air bronchogram (n=18), pleural thickening or pleural effusion (14/54), consolidation (12/54), lesions in the upper lobes (12/54), interlobular septal thickening (11/54), reversed halo sign (9/54), single lesion (8/54), cavitaties (4/54), bronchial wall thickening (3/54), intrathoracic lymph node enlargement (2/54).

scholarly journals The chest CT features of coronavirus disease 2019 (COVID-19) in China: a meta-analysis of 19 retrospective studies

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Haitao Yang ◽  
Yuzhu Lan ◽  
Xiujuan Yao ◽  
Sheng Lin ◽  
Baosong Xie
Keyword(s):  
Retrospective Studies ◽  
Meta Analysis ◽  
Ct Imaging ◽  
Chest Ct ◽  
Chinese Patients ◽  
Wall Thickening ◽  
Random Effects Models ◽  
Distribution Features ◽  
Ct Features ◽  
Interlobular Septal Thickening

Abstract Objective Aimed to summarize the characteristics of chest CT imaging in Chinese hospitalized patients with Coronavirus Disease 2019 (COVID-19) to provide reliable evidence for further guiding clinical routine. Methods PubMed, Embase and Web of Science databases were searched to identify relevant articles involving the features of chest CT imaging in Chinese patients with COVID-19. All data were analyzed utilizing R i386 4.0.0 software. Random-effects models were employed to calculate pooled mean differences. Results 19 retrospective studies (1332 cases) were included. The results demonstrated that the combined proportion of ground-glass opacities (GGO) was 0.79 (95% CI 0.68, 0.89), consolidation was 0.34 (95% CI 0.23, 0.47); mixed GGO and consolidation was 0.46 (95% CI 0.37; 0.56); air bronchogram sign was 0.41 (95% CI 0.26; 0.55); crazy paving pattern was 0.32 (95% CI 0.17, 0.47); interlobular septal thickening was 0.55 (95% CI 0.42, 0.67); reticulation was 0.30 (95% CI 0.12, 0.48); bronchial wall thickening was 0.24 (95% CI 0.11, 0.40); vascular enlargement was 0.74 (95% CI 0.64, 0.86); subpleural linear opacity was 0.28 (95% CI 0.12, 0.48); intrathoracic lymph node enlargement was 0.03 (95% CI 0.00, 0.07); pleural effusions was 0.03 (95% CI 0.02, 0.06). The distribution in lung: the combined proportion of central was 0.05 (95% CI 0.01, 0.11); peripheral was 0.74 (95% CI 0.62, 0.84); peripheral involving central was 0.38 (95% CI 0.19, 0.75); diffuse was 0.19 (95% CI 0.06, 0.32); unifocal involvement was 0.09 (95% CI 0.05, 0.14); multifocal involvement was 0.57 (95% CI 0.48, 0.68); unilateral was 0.16 (95% CI 0.10, 0.23); bilateral was 0.83 (95% CI 0.78, 0.89); The combined proportion of lobes involved (> 2) was 0.70 (95% CI 0.61, 0.78); lobes involved (≦ 2) was 0.35 (95% CI 0.26, 0.44). Conclusion GGO, vascular enlargement, interlobular septal thickening more frequently occurred in patients with COVID-19, which distribution features were peripheral, bilateral, involved lobes > 2. Therefore, based on chest CT features of COVID-19 mentioned, it might be a promising means for identifying COVID-19.

scholarly journals CT findings of patients infected with SARS-CoV-2

2020 ◽  
Author(s):  
Xiaoyang Wang ◽  
Chenbin Liu ◽  
Liang Hong ◽  
Cuiyun Yuan ◽  
Jiguang Ding ◽  
...  
Keyword(s):  
Wall Thickening ◽  
Bronchial Wall ◽  
Pleural Thickening ◽  
Ct Findings ◽  
Lymph Node Enlargement ◽  
Peripheral Area ◽  
Reversed Halo Sign ◽  
Air Cavities ◽  
Single Lesion ◽  
Interlobular Septal Thickening

Abstract Objective: We aimed to describe the chest CT findings in sixty-seven patients infected by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Method and material: We retrospectively reviewed 67 patients hospitalized in Ruian People's Hospital. All the patients received the positive diagnosis of SARS-CoV-2 infection. The CT and clinical data were collected between January 23 rd , 2020 and February 10 th , 2020. The CT images were analyzed by the senior radiologists. Conclusion: There are 54 patients with positive CT findings and 13 patients with negative CT findings. The typical CT findings in hospitalized patients with SARS-CoV-2 infection were ground glass opacities (42/54), lesions located in the peripheral area (50/54), multiple lesions (46/54), and lesions located in the lower lobes (42/54). There were less typical CT findings, including air bronchogram (18/54), pleural thickening or pleural effusion (14/54), consolidation (12/54), lesions in the upper lobes (12/54), interlobular septal thickening (11/54), reversed halo sign (9/54), single lesion (8/54), air cavities (4/54), bronchial wall thickening (3/54), and intrathoracic lymph node enlargement (2/54).

scholarly journals Chest CT for early detection and management of coronavirus disease (COVID-19): a report of 314 patients admitted to Emergency Department with suspected pneumonia

2020 ◽  
Vol 125 (10) ◽  
pp. 931-942 ◽  
Author(s):  
Cartocci Gaia ◽  
Colaiacomo Maria Chiara ◽  
Lanciotti Silvia ◽  
Andreoli Chiara ◽  
De Cicco Maria Luisa ◽  
...  
Keyword(s):  
Emergency Department ◽  
Early Detection ◽  
Patient Management ◽  
Chest Ct ◽  
Wall Thickening ◽  
Italian Population ◽  
Rt Pcr ◽  
Arterial Blood ◽  
Ct Findings ◽  
Route Of Transmission

Abstract Purpose The purpose of our study was to assess the potential role of chest CT in the early detection of COVID-19 pneumonia and to explore its role in patient management in an adult Italian population admitted to the Emergency Department. Methods Three hundred and fourteen patients presented with clinically suspected COVID-19, from March 3 to 23, 2020, were evaluated with PaO2/FIO2 ratio from arterial blood gas, RT-PCR assay from nasopharyngeal swab sample and chest CT. Patients were classified as COVID-19 negative and COVID-19 positive according to RT-PCR results, considered as a reference. Images were independently evaluated by two radiologists blinded to the RT-PCR results and classified as “CT positive” or “CT negative” for COVID-19, according to CT findings. Results According to RT-PCR results, 152 patients were COVID-19 negative (48%) and 162 were COVID-19 positive (52%). We found substantial agreement between RT-PCR results and CT findings (p < 0.000001), as well as an almost perfect agreement between the two readers. Mixed GGO and consolidation pattern with peripheral and bilateral distribution, multifocal or diffuse abnormalities localized in both upper lung and lower lung, in association with interlobular septal thickening, bronchial wall thickening and air bronchogram, showed higher frequency in COVID-positive patients. We also found a significant correlation between CT findings and patient’s oxygenation status expressed by PaO2/FIO2 ratio. Conclusion Chest CT has a useful role in the early detection and in patient management of COVID-19 pneumonia in a pandemic. It helps in identifying suspected patients, cutting off the route of transmission and avoiding further spread of infection.

scholarly journals Chest CT accuracy in the diagnosis of SARS-CoV-2 infection: initial experience in a cancer center

2020 ◽  
Vol 53 (4) ◽  
pp. 211-215 ◽  
Author(s):  
Paula Nicole Vieira Pinto Barbosa ◽  
Almir Galvão Vieira Bitencourt ◽  
Gabriel Diaz de Miranda ◽  
Maria Fernanda Arruda Almeida ◽  
Rubens Chojniak
Keyword(s):  
High Sensitivity ◽  
High Specificity ◽  
Chest Ct ◽  
Cancer Center ◽  
Rt Pcr ◽  
Interpretation Criteria ◽  
Single Center Study ◽  
Constrained Environments ◽  
Diagnosis Of Cancer ◽  
Sensitivity Specificity

Abstract Objective: To evaluate the accuracy of chest computed tomography (CT) in patients with suspected severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) infection at a cancer center. Materials and Methods: This retrospective single-center study selected 91 patients who had chest CT and real-time polymerase chain reaction (RT-PCR) test collected at the same day. CT results were classified in negative, typical, indeterminate or atypical findings. Diagnostic accuracy, sensitivity and specificity were calculated for two different scenarios: in the first, only typical findings on CT were considered positive; in the second, both typical and indeterminate findings were considered positive. Results: Mean patients’ age was 58.2 years, most were male (60.4%) and had prior diagnosis of cancer (85.7%). CT showed typical findings in 28.6%, indeterminate findings in 24.2% and atypical findings in 26.4%. RT-PCR results were positive for SARS-CoV-2 in 27.5%. The sensitivity, specificity and accuracy in the first and second scenarios were respectively 64.0%, 84.8% and 79.1%, and 92.0%, 62.1% and 70.3%. Conclusion: CT has a high accuracy for the diagnosis of SARS-CoV-2 infection. Different interpretation criteria can provide either high sensitivity or high specificity. CT should be integrated as a triage test in resource-constrained environments during the pandemic to assist in the optimization of PCR-tests, isolation beds and intensive care units.

scholarly journals Chest CT For Early Detection And Management Of Coronavirus Disease (COVID-19): A Report Of 314 Patients Admitted To Emergency Department With Suspected Pneumonia

2020 ◽  
Author(s):  
Gaia Cartocci ◽  
Maria Chiara Colaiacomo ◽  
Silvia Lanciotti ◽  
Chiara Andreoli ◽  
Maria Luisa De Cicco ◽  
...  
Keyword(s):  
Early Detection ◽  
Chest Ct ◽  
Wall Thickening ◽  
Nasopharyngeal Swab ◽  
Italian Population ◽  
Rt Pcr ◽  
Perfect Agreement ◽  
Arterial Blood ◽  
Ct Findings ◽  
Route Of Transmission

Abstract PURPOSE: The purpose of our study was to assess the potential role of chest CT for the early detection of COVID-19 pneumonia and to explore its role in patient management in an adult Italian population admitted to the Emergency Department.METHODS: 314 patients presented with clinically suspected COVID-19, From March 3 rd to 23 th 2020, were evaluated with PaO2/FIO2 ratio from arterial blood gas, RT-PCR assay from nasopharyngeal swab sample and chest CT. Patients were classified as COVID-19 negative and COVID-19 positive according to RT-PCR results, considered as a reference. Images were independently evaluated by two radiologists blinded to the RT-PCR results and classified as “CT positive” or “CT negative” for COVID-19, according to CT findings.RESULTS: According to RT-PCR results, 152 patients were COVID-19 negative (48%) and 162 were COVID-19 positive (52%). We found substantial agreement between RT-PCR results and CT findings (p<0.000001), as well as an almost perfect agreement between the two readers. Mixed GGO and consolidation pattern with peripheral and bilateral distribution, multifocal or diffuse abnormalities localized in both upper and lower lung, in association with interlobular septal thickening, bronchial wall thickening and air bronchogram, showed higher frequency in COVID positive patients. We also found a significant correlation between CT findings and patient’s oxygenation status expressed by PaO2/FIO2 ratio.CONCLUSION: Chest CT is a vital component in the early detection and in patients management of COVID-19 pneumonia in a pandemic. It allows to identify suspected patients, cutting off the route of transmission and avoiding further spread of infection.

scholarly journals Influenza A (H1N1) pneumonia: HRCT findings

2013 ◽  
Vol 39 (3) ◽  
pp. 323-329 ◽  
Author(s):  
Viviane Brandao Amorim ◽  
Rosana Souza Rodrigues ◽  
Miriam Menna Barreto ◽  
Glaucia Zanetti ◽  
Bruno Hochhegger ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Ground Glass ◽  
Wall Thickening ◽  
H1n1 Infection ◽  
Air Trapping ◽  
Bronchial Wall ◽  
Influenza A H1n1 ◽  
H1n1 Pneumonia ◽  
Interlobular Septal Thickening

OBJECTIVE: To describe aspects found on HRCT scans of the chest in patients infected with the influenza A (H1N1) virus. METHODS: We retrospectively analyzed the HRCT scans of 71 patients (38 females and 33 males) with H1N1 infection, confirmed through laboratory tests, between July and September of 2009. The HRCT scans were interpreted by two thoracic radiologists independently, and in case of disagreement, the decisions were made by consensus. RESULTS: The most common HRCT findings were ground-glass opacities (85%), consolidation (64%), or a combination of ground-glass opacities and consolidation (58%). Other findings were airspace nodules (25%), bronchial wall thickening (25%), interlobular septal thickening (21%), crazy-paving pattern (15%), perilobular pattern (3%), and air trapping (3%). The findings were frequently bilateral (89%), with a random distribution (68%). Pleural effusion, when observed, was typically minimal. No lymphadenopathy was identified. CONCLUSIONS: The most common findings were ground-glass opacities and consolidations, or a combination of both. Involvement was commonly bilateral with no axial or craniocaudal predominance in the distribution. Although the major tomographic findings in H1N1 infection are nonspecific, it is important to recognize such findings in order to include infection with the H1N1 virus in the differential diagnosis of respiratory symptoms.

scholarly journals Chest CT findings in patients with dysphagia and aspiration: a systematic review

2017 ◽  
Vol 43 (4) ◽  
pp. 313-318 ◽  
Author(s):  
Betina Scheeren ◽  
Erissandra Gomes ◽  
Giordano Alves ◽  
Edson Marchiori ◽  
Bruno Hochhegger
Keyword(s):  
Systematic Review ◽  
Pulmonary Nodules ◽  
Chest Ct ◽  
Pulmonary Aspiration ◽  
Cochrane Library ◽  
Elderly Subjects ◽  
Wall Thickening ◽  
Bronchial Wall ◽  
Ct Findings ◽  
Ground Glass Attenuation

ABSTRACT The objective of this systematic review was to characterize chest CT findings in patients with dysphagia and pulmonary aspiration, identifying the characteristics and the methods used. The studies were selected from among those indexed in the Brazilian Virtual Library of Health, LILACS, Indice Bibliográfico Español de Ciencias de la Salud, Medline, Cochrane Library, SciELO, and PubMed databases. The search was carried out between June and July of 2016. Five articles were included and reviewed, all of them carried out in the last five years, published in English, and coming from different countries. The sample size in the selected studies ranged from 43 to 56 patients, with a predominance of adult and elderly subjects. The tomographic findings in patients with dysphagia-related aspiration were varied, including bronchiectasis, bronchial wall thickening, pulmonary nodules, consolidations, pleural effusion, ground-glass attenuation, atelectasis, septal thickening, fibrosis, and air trapping. Evidence suggests that chest CT findings in patients with aspiration are diverse. In this review, it was not possible to establish a consensus that could characterize a pattern of pulmonary aspiration in patients with dysphagia, further studies of the topic being needed.

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