scholarly journals Preoperative Neutrophil Lymphocyte Ratio as a Prognostic Factor for Survival in Non-metastatic Renal Cell Carcinoma

2020 ◽  
Vol 82 (s6) ◽  
Author(s):  
J. CHINDAPRASIRT ◽  
W. SIRITHANAPHOL
Keyword(s):  
Renal Cell Carcinoma ◽  
Prognostic Factor ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio

The Role of Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio, and Platelets in the Prognosis of Metastatic Renal Cell Carcinoma

Oncology ◽  
2019 ◽  
Vol 97 (1) ◽  
pp. 7-17 ◽  
Author(s):  
Joanna Huszno ◽  
Zofia Kolosza ◽  
Jolanta Mrochem-Kwarciak ◽  
Tomasz Rutkowski ◽  
Krzysztof Skladowski
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Platelet Lymphocyte Ratio

scholarly journals The clinical and prognostic value of the neutrophil lymphocyte ratio, the platelet lymphocyte ratio and mean platelet volume in tinnitus patients

2021 ◽  
Vol 38 (3) ◽  
pp. 251-254
Author(s):  
Ayşe ÇEÇEN ◽  
Esra KAVAZ ◽  
Seda GÜN
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Neck Region ◽  
Pathology Report ◽  
Lower Lip ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio

Approximately 15% of renal cell carcinomas metastasize to the head and neck region. Here in, we report a rare case report of a patient who underwent nephrectomy for renal cell carcinoma (RCC) ten years ago and presented with metastatic renal cell carcinoma on her lower lip. A 65-year-old woman presented with a rapidly growing mass on the lower lip. Pathology report resulted in renal cell carcinoma metastasis. Although metastatic renal cell carcinoma to the head and neck is uncommon, metastasis should be considered in the differential diagnosis of a rapidly growing vascular lesion in the head and neck area of patients with renal cell carcinoma.

Validation of the pretreatment neutrophil-lymphocyte ratio as prognostic factor regarding cancer-specific, metastasis-free, and overall survival in a European cohort of patients with renal cell carcinoma.

2013 ◽  
Vol 31 (6_suppl) ◽  
pp. 410-410 ◽  
Author(s):  
Georg C. Hutterer ◽  
Martin Pichler ◽  
Caroline Stoeckigt ◽  
Thomas F. Chromecki ◽  
Tatjana Stojakovic ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Overall Survival ◽  
Prognostic Factors ◽  
Prognostic Factor ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Prognostic Significance ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Metastatic Rcc

410 Background: The neutrophil-lymphocyte ratio (NLR) has been proposed as an indicator of systemic inflammation response and data from previous studies report controversial results about its independent prognostic role in non-metastatic renal cell carcinoma (RCC). Thus, we decided to evaluate the prognostic significance of NLR in a large cohort of RCC patients. Methods: Data from 843 consecutive non-metastatic RCC patients, operated with radical nephrectomy or nephron sparing surgery between 2000 and 2010 at a single tertiary academic center, were evaluated retrospectively. Pre-treatment NLR was calculated one day before surgical intervention. Patients were categorized according to a NLR cut-off value of 3.2. Cancer-specific–, metastasis-free–, as well as overall survival were assessed using the Kaplan-Meier method. To evaluate NLR’s independent prognostic significance, a multivariate Cox regression model was performed for all three endpoints. Results: An increased NLR was associated with several well established prognostic factors including tumor size, tumor grade, and histologic tumor necrosis (all p<0.05). Although an increased NLR was statistically significantly associated with poor outcome for all clinical endpoints (p<0.001), multivariate analysis identified an increased NLR as an independent prognostic factor for overall (HR=1.58, 95% CI=1.12-2.20, p=0.008), but not for cancer-specific (HR=1.55, 95% CI=0.89-2.70, p=0.116), nor for metastasis-free survival (HR=1.37, 95% CI=0.88-2.14, p=0.160). Conclusions: Risk prediction for cancer-related endpoints using NLR does not seem to add independent prognostic information to other well established prognostic factors in patients with non-metastatic RCC. Regarding patients’ overall survival, an increased NLR represented an independent risk factor, which might reflect a higher risk for cardiovascular, infectious, as well as for gastrointestinal morbidities and mortalities.

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