scholarly journals Case series of retinal capillary hemangioma in patients with and without von hippel lindau disease

2020 ◽  
Vol 15 (2) ◽  
Author(s):  
Nor Syahira Shariffudin ◽  
Azian Adnan ◽  
Hanizasurana Hashim ◽  
Khairy Shamel Sonny Teo
Keyword(s):  
Case Series ◽  
Capillary Hemangioma ◽  
Von Hippel Lindau ◽  
Retinal Capillary ◽  
Von Hippel Lindau Disease ◽  
Retinal Capillary Hemangioma

scholarly journals A family with Von Hippel-Lindau disease with different presentations

1970 ◽  
Vol 14 (1) ◽  
pp. 17-24
Author(s):  
Ching-lin Wong ◽  
Ming-Yueh Lee ◽  
R. Sunder ◽  
R. Jamalia ◽  
T.V.N. Karunakar ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Laser Photocoagulation ◽  
Case Series ◽  
Capillary Hemangioma ◽  
Exudative Retinal Detachment ◽  
Fundus Examination ◽  
Von Hippel Lindau ◽  
Retinal Capillary ◽  
Von Hippel Lindau Disease ◽  
Retinal Capillary Hemangioma

Objective: To report three cases of Von Hippel-Lindau (VHL) disease from a family with different presentations.Method: Case series.Results: Case 1, a 14-year-old Malay boy with a history of gradual blurring of vision in both eyes presented with sudden deterioration of right vision. Fundus examination revealed bilateral retinal capillary hemangioma with exudative retinal detachment. His right eye underwent combination therapy of laser photocoagulation, cryotherapy, intravitreal anti-VEGF and photodynamic therapy, but failed to improve vision. His left visiondeteriorated and eventually required surgical intervention. Case 2 was the sister of case 1. She was a 17-year-old Malay girl who presented with sudden onset of left eye pain and redness. Diagnosis of left eye rubeotic glaucoma with closed funnel retinal detachment secondary to a huge retinal hemangioma was made. She underwent left eye external drainage of subretinal fluid plus anterior retinal cryopexy. The rubeotic vessel regressed postoperatively and IOP reduced. Case 3 was the eldest sister of case 1; a 19-year-old Malay girl who came for eye screening after two of her siblings were diagnosed with VHL. She was, however, asymptomatic. Fundus examination revealed right retinal capillary hemangioma. She was treated with laser photocoagulation and her condition remained stable. Systemic investigations identified midline cystic masses in the brain, spine and pancreas. Conclusions: This case series highlight different clinical pictures of Von Hippel-Lindau disease. As marked visual loss is a dreadful sequela of VHL, it is important to screen the family members as early detection and management of ocular and systemic lesions save sight and life.

Retinal capillary hemangioma and von Hippel-Lindau disease

2019 ◽  
Vol 152 (7) ◽  
pp. 290
Author(s):  
Antonio Ramos Suárez ◽  
Ana María Alfaro Juárez ◽  
Carlos Sánchez Merino
Keyword(s):  
Capillary Hemangioma ◽  
Von Hippel Lindau ◽  
Retinal Capillary ◽  
Von Hippel Lindau Disease ◽  
Retinal Capillary Hemangioma

Retinal capillary hemangioma in von Hippel-Lindau disease

2005 ◽  
Vol 40 (2) ◽  
pp. 192-194 ◽  
Author(s):  
Craig Moskowitz ◽  
Chaim Edelstein ◽  
Mila Oh ◽  
Miguel N. Burnier
Keyword(s):  
Capillary Hemangioma ◽  
Von Hippel Lindau ◽  
Retinal Capillary ◽  
Von Hippel Lindau Disease ◽  
Retinal Capillary Hemangioma

Brachytherapy for Peripheral Retinal Capillary Haemangioblastoma in von Hippel-Lindau Disease

2021 ◽  
Vol 238 (07) ◽  
pp. 781-787
Author(s):  
Sami Dalbah ◽  
Nikolaos E. Bechrakis ◽  
Henning Thomasen ◽  
Dirk Flühs ◽  
Philipp Rating ◽  
...  
Keyword(s):  
Macular Oedema ◽  
Case Series ◽  
Vitreoretinal Surgery ◽  
Complication Rates ◽  
Retrospective Case ◽  
Tumour Control ◽  
Von Hippel Lindau ◽  
Retinal Capillary ◽  
Von Hippel Lindau Disease ◽  
Epiretinal Gliosis

Abstract Aim To report our experience with 106ruthenium-brachytherapy of peripheral capillary haemangioblastomas in patients with von Hippel-Lindau disease. Design Retrospective case series. Methods A total of 53 haemangioblastomas, treated with 106ruthenium-brachytherapy, were included in our study. The applied radiation dose, visual outcome, angioma activity, need for vitreoretinal surgery and incidence of secondary complications such as macular oedema, secondary glaucoma, vitreous haemorrhage, and epiretinal gliosis were assessed. Results All treated eyes could be preserved. In 11 patients (20.8%), single brachytherapy did not achieve complete inactivation of the tumour. 31% developed macular oedema postoperatively. Tractional retinal detachment developed in 23.8%, and epiretinal gliosis was observed in 2.4% of patients. Vitreoretinal surgery was necessary in 50% of all treated eyes. At the end of the follow-up, 40.5% of all treated eyes achieved visual acuity (VA) of 0.6 or better, and one third reached a VA of less than 0.1. Mean irradiation dose to the tumour apex was 144 Gy. Higher apex doses correlated with better tumour control of irradiated haemanigoblastomas and lower complication rates. Conclusions Brachytherapy of peripheral retinal capillary haemangioblastomas is an effective treatment modality. Higher irradiation doses seem to lead to more successful treatment.

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