scholarly journals CLINICALAND ENDOSCOPIC PROFILE OF PEPTIC ULCER DISEASE IN LIVER CIRRHOTICS : STUDY AT A LIVER TRANSPLANT CENTRE IN SOUTH INDIA

2020 ◽  
pp. 1-2
Author(s):  
MS Revathy ◽  
Amiya Ranjan ◽  
B. Sumathi ◽  
Manimaran M
Keyword(s):  
Liver Cirrhosis ◽  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Refractory Ascites ◽  
Biliary Cirrhosis ◽  
Gi Endoscopy ◽  
Ulcer Disease ◽  
Upper Gi ◽  
Upper Gi Endoscopy ◽  
Cirrhotic Patients

Background: Peptic ulcer disease in patients with liver cirrhosis poses significant morbidity and mortality . It is also a cause for gastrointestinal bleed . Our study aims at providing a clinical and endoscopic profile of peptic ulcer disease in patients suffering from liver cirrhosis . Objective: Providing an insight into the clinical and endoscopic profile of patients suffering from liver cirrhosis and peptic ulcer disease, with special reference to Child Pugh score, spontaneous bacterial peritonitis, refractory ascites and other comorbidities. Methods: This study was conducted in the Department of Medical Gastroenterology, Govt Stanley medical college, Chennai from September 2018 to April 2019. All cirrhotic patients underwent relevant blood investigations, ultrasound abdomen, portal vein doppler and upper GI endoscopy. Gastric ulcers were biopsied according to standard protocol. RUT was not performed in all cases for H.Pylori detection . Results: A total of 361 cirrhotic patients that underwent upper GI endoscopy, 45 patients were incuded in our study based on the inclusion criteria. The prevalence of peptic ulcer disease in liver cirrhotics was 12.4% . Males to females ratio of 38:7. Mean age was 38 years ±2.8. Mean CTP score was 8.42±1.90 . median of 8 , mode 10 . Ascites was noted in 37, SBP in 22 and refractory ascites in 4. Etiology for cirrhosis was alcohol (44.4%) , cryptogenic(17.8%) , hepatitis B(15.6%) , Budd Chiari syndrome(8.9%) , hepatitis C(4.4%), wilsons disease (2.2%) , secondary biliary cirrhosis(2.2%) , autoimmune hepatitis(2.2%) . 23 had CPT score B, followed by CPT C in 15 and CPT A in 7 . Conclusion: In conclusion, a significant proportion of patients with cirrhosis develop PUD. Furthermore, H pylori infection and NSAIDs are not the only, or perhaps even the most important, risk factors for PUD in patients with cirrhosis. These observations have important practical implications for physicians caring for patients with chronic liver disease.

scholarly journals Prevalence of helicobacter pylori infection in patients with peptic ulcer disease at Kathmandu Model Hospital

2018 ◽  
Vol 8 (4) ◽  
pp. 3-7
Author(s):  
Rajesh Dhoj Joshi ◽  
Sachin Khadka ◽  
Deepak Man Joshi ◽  
Arun Kadel ◽  
Ganesh Dangal ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Rapid Urease Test ◽  
Gi Endoscopy ◽  
Ulcer Disease ◽  
Upper Gi ◽  
Urease Test ◽  
Upper Gi Endoscopy ◽  
H Pylori

Introduction: Endoscopic rapid urease test is a simple and most widely used test to detect the presence of urease in the gastric mucosa. Many studies have reported prevalence of H. pylori infection in relation to age, gender and site of ulcer. Therefore, this study was designed to determine the prevalence and significance of H. pylori in peptic ulcer disease. Methods: A retrospective review was carried out for patients with peptic ulcer disease who had undergone upper GI endoscopy in Department of Internal Medicine at Kathmandu Model Hos­pital. The records from January 2013 to December 2017 were analyzed. Any patient with previously diagnosed peptic ulcer, history of active bleeding, cancer and incomplete records were excluded. Peptic ulcer associated with H. pylori was diagnosed on the basis of endoscopic rapid urease test. Results: Among the 418 diagnosed case of peptic ulcer disease by upper GI endoscopy from Jan 2013 to Dec 2017, 213 tested positive for H. pylori by rapid urease test. Among the positive cases, over a half were males patients. Majority (23.9%) of the patients were in the age group of 35-44 years. Prevalence of H. pylori in duodenal ulcer was 51.6% followed by combined gastro-duodenal ulcer (26.8%) and gastric ulcer (21.6%). H. pylori was significantly associated with duodenal ulcer (p<0.0001). Conclusion: This study demonstrated relatively high prevalence of H. pylori infection in patients with duodenal ulcer who had undergone upper GI endoscopy.

scholarly journals Helicobacter pylori Infection and Peptic Ulcer Disease in Patients with Liver Cirrhosis

2008 ◽  
Vol 23 (1) ◽  
pp. 16 ◽  
Author(s):  
Dong Joon Kim ◽  
Hak Yang Kim ◽  
Sung Jung Kim ◽  
Tae Ho Hahn ◽  
Myoung Kuk Jang ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Liver Cirrhosis ◽  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Helicobacter Pylori Infection ◽  
Ulcer Disease

scholarly journals Gastrointestinal bleeding in pregnant patients with cirrhosis: Pathophysiology, review of outcomes, and management

2018 ◽  
Vol 6 (25) ◽  
pp. 19-25
Author(s):  
Abdussalam Shredi ◽  
Benjamin Elberson
Keyword(s):  
Liver Cirrhosis ◽  
Peptic Ulcer ◽  
Gastrointestinal Bleeding ◽  
Peptic Ulcer Disease ◽  
Esophageal Varices ◽  
Rare Event ◽  
Ulcer Disease ◽  
Common Causes ◽  
In Pregnancy

Pregnancy is a rare event in patients with cirrhosis because the metabolic and hormonalchanges associated with cirrhosis lead to anovulation and amenorrhea. Liver cirrhosis withportal hypertension is considered one of the most common causes of gastrointestinal bleedingin general and comes after peptic ulcer disease. Gastrointestinal bleeding in the setting ofportal hypertension occurs secondary to either esophageal varices or portal hypertensivegastropathy. Its management can be challenging in general, and pregnancy can only make itmore complicated. In this article we will review the management of variceal gastrointestinalbleeding in pregnancy.

Peptic ulcer disease in liver cirrhosis and chronic hepatitis: impact of portal hypertension

2014 ◽  
Vol 49 (9) ◽  
pp. 1051-1057 ◽  
Author(s):  
Chang Seok Bang ◽  
Gwang Ho Baik ◽  
Jong Hyeok Kim ◽  
Jin Bong Kim ◽  
Ki Tae Suk ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Chronic Hepatitis ◽  
Peptic Ulcer ◽  
Portal Hypertension ◽  
Peptic Ulcer Disease ◽  
Ulcer Disease

scholarly journals Conscious sedation using propofolversusmidazolam in cirrhotic patients during upper GI endoscopy: A comparative study

JGH Open ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Essam A Wahab ◽  
Emad F Hamed ◽  
Hanan S Ahmad ◽  
Sameh M Abdel Monem ◽  
Talaat Fathy
Keyword(s):  
Comparative Study ◽  
Conscious Sedation ◽  
Gi Endoscopy ◽  
Upper Gi ◽  
Upper Gi Endoscopy ◽  
Cirrhotic Patients

538 IMPROVING HELICOBACTER PYLORI TESTING IN PATIENTS WITH ACUTE UPPER GI BLEEDING DUE TO PEPTIC ULCER DISEASE (POSTER PRESENTATION)

2020 ◽  
Vol 158 (6) ◽  
pp. S-109
Author(s):  
Jessica Bernica ◽  
Rhonda A. Cole ◽  
Avegail G. Flores ◽  
Clark D. Hair ◽  
Ruben Hernaez ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Poster Presentation ◽  
Gi Bleeding ◽  
Ulcer Disease ◽  
Upper Gi Bleeding ◽  
Upper Gi
Sign in / Sign up

Export Citation Format

Share Document