scholarly journals BREAST CANCER METASTASIS TO THE THYROID GLAND: A RARE CASE REPORT WITH DIAGNOSTIC DILEMM

2020 ◽  
pp. 1-2
Author(s):  
Rajneesh Rawat ◽  
Sunil M Lanjewar ◽  
Mrinalini M Borkar ◽  
Jyoti Baghel
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Thyroid Gland ◽  
Cancer Metastasis ◽  
Ductal Carcinoma ◽  
Metastatic Lesion ◽  
Breast Cancer Metastasis ◽  
Breast Lump ◽  
Rare Case Report ◽  
Simple Mastectomy

Introduction: Metastasis to thyroid gland is very rare; with breast cancer metastasizing to thyroid is extremely rare. Here, we report a case of metastatic lesion in the thyroid from breast carcinoma in a 43 year old female who presented to us with a right breast lump for 1.5 years along with thyroid swelling for 6 months. Results: FNAC of breast lump showed ductal carcinoma while FNAC of thyroid nodule was inconclusive. CECT showed right breast neoplasm with malignant deposits in isthmus of thyroid. She underwent right simple mastectomy with axillary clearance and total thyroidectomy followed by chemotherapy. Histopathology analysis showed invasive ductal carcinoma in isthmus of thyroid.This was confirmed by immunohistochemistry, which revealed positive for GATA- 3and negative for TTF1 and Calcitonin. Conclusion: This case report highlights the importance of a correct early diagnostic work up.Immunohistochemical panels are helpful in differentiating between primary and secondary tumors.Also, thyroidectomy may be beneficial for local disease control and prevent the potential morbidity of tumor extension related to airway.

Breast cancer metastasis to the thyroid gland – A case report

2020 ◽  
Author(s):  
Aikaterini Michou ◽  
Ioannis Kakoulidis ◽  
Ioannis Ilias ◽  
Evangelia Venaki ◽  
Eftychia Koukkou
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Thyroid Gland ◽  
Cancer Metastasis ◽  
Breast Cancer Metastasis ◽  
Metastasis To The Thyroid

scholarly journals Rare Metastases in Colorectum of Infiltrating Ductal Breast Cancer: A Rare Case Report and Review

2020 ◽  
Author(s):  
Zhijun Zhang ◽  
Tao Li ◽  
Yuemin Li ◽  
Dongxu Li ◽  
Kai Zhang
Keyword(s):  
Breast Cancer ◽  
Cancer Metastasis ◽  
Ductal Carcinoma ◽  
Therapeutic Option ◽  
Radical Mastectomy ◽  
Left Breast ◽  
Breast Cancer Metastasis ◽  
Positron Emission ◽  
Rare Case Report ◽  
Lost To Follow Up

Abstract Background: Breast ductal carcinoma hardly metastasizes to colorectum and the effect of surgery is controversial. We treated one case of patients with breast ductal carcinoma metastasizes to colorectum with surgery and discussed current management experience of breast cancer metastasizing to colorectum by reviewing the literature. Case Presentation: A 37-year-old woman underwent a modified radical mastectomy three years ago for right breast cancer and developed left breast cancer with right breast cancer suspiciously metastasizing to colorectum, left ovary along with oviduct, pancreas, and left acetabulum according to positron emission tomography-computed tomography. Then she had chosen to give up further therapy but was admitted to our department complaining of shapeless feces and mucus pus and blood in stool for 2 years with the process of aggravating symptoms for recent 2 months. Colonoscopy revealed the existence of colorectal carcinoma. She received laparoscopic combined abdominal perineal resection and bilateral ovarian salpingectomy. Postoperative pathology as well as immunohistochemistry supported the origin of primary breast infiltrating ductal cancer. She remained tamoxifen therapy and was alive until she was lost to follow-up.Conclusions: Clinicians must pay attention to any gastro-intestinal symptoms of patients with a medical history of breast cancer since the incipient symptoms of breast cancer metastasis to colorectum are insidious. Definite diagnosis may be difficult even by endoscopy. Surgery should be considered as a therapeutic option and definite diagnostic means combined with immunohistochemistry.

Pleomorphic Invasive Lobular Cancer of the Breast Presenting with Orbital Metastasis: A Case Report

2021 ◽  
Vol 17 ◽  
Author(s):  
Ebru Yılmaz ◽  
Nilgün Güldoğan ◽  
Aydan Arslan ◽  
Ceyda Civan
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cancer Metastasis ◽  
Left Breast ◽  
Breast Cancer Metastasis ◽  
Mri Findings ◽  
Blurred Vision ◽  
Orbital Metastasis ◽  
Invasive Lobular Cancer ◽  
Lobular Cancer

Background: Orbital metastasis of breast cancer is an unusual condition, especially in the absence of a previous diagnosis of primary breast cancer. The main MRI findings in patients with orbital metastasis are retroorbital soft tissue with thickening of extraocular muscles. Paradoxical enophtalmos secondary to fibrosis can be seen. Case Report: In this case report we present a 75-year-old female patient with left eye pain and blurred vision and retraction. Although there was no evidence of malignancy in the biopsy of the orbita; since the patient's complaints continued despite idiopathic pseudotumor treatment; mammography was recommended to rule out the possibility of breast cancer metastasis. Her mammography revealed a suspicious lesion in the left breast and proved to be pleomorphic invasive lobular cancer. Conclusion: Breast cancer metastasis should be kept in mind in women with pseudotumor -like involvement of the orbita.

scholarly journals Ureter - an unusual site of breast cancer metastasis: A case report

2019 ◽  
Vol 7 (20) ◽  
pp. 3347-3352
Author(s):  
Zhong-Han Zhou ◽  
Li-Jiang Sun ◽  
Gui-Ming Zhang
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cancer Metastasis ◽  
Breast Cancer Metastasis ◽  
Unusual Site

Serum ANGPTL2 Levels Reflect Clinical Features of Breast Cancer Patients: Implications for the Pathogenesis of Breast Cancer Metastasis

2014 ◽  
Vol 29 (3) ◽  
pp. 239-245 ◽  
Author(s):  
Motoyoshi Endo ◽  
Yutaka Yamamoto ◽  
Masahiro Nakano ◽  
Tetsuro Masuda ◽  
Haruki Odagiri ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Clinical Features ◽  
Cancer Progression ◽  
Breast Cancer Cells ◽  
Cancer Metastasis ◽  
Ductal Carcinoma ◽  
Breast Cancer Metastasis ◽  
Breast Cancer Patients

Introduction Breast cancer is a leading cause of cancer-related death in women worldwide, and its metastasis is a major cause of disease mortality. Therefore, identification of the mechanisms underlying breast cancer metastasis is crucial for the development of therapeutic and diagnostic strategies. Our recent study of immunodeficient female mice transplanted with MDA-MB231 breast cancer cells demonstrated that tumor cell-derived angiopoietin-like protein 2 (ANGPTL2) accelerates metastasis through both increasing tumor cell migration in an autocrine/paracrine manner, and enhancing tumor angiogenesis. To determine whether ANGPTL2 contributes to its clinical pathogenesis, we asked whether serum ANGPTL2 levels reflect the clinical features of breast cancer progression. Methods We monitored the levels of secreted ANGPTL2 in supernatants of cultured proliferating MDA-MB231 cells. We also determined whether the circulating ANGPTL2 levels were positively correlated with cancer progression in an in vivo breast cancer xenograft model using MDA-MB231 cells. Finally, we investigated whether serum ANGPTL2 levels were associated with clinical features in breast cancer patients. Results Both in vitro and in vivo experiments showed that the levels of ANGPTL2 secreted from breast cancer cells increased with cell proliferation and cancer progression. Serum ANGPTL2 levels in patients with metastatic breast cancer were significantly higher than those in healthy subjects or in patients with ductal carcinoma in situ or non-metastatic invasive ductal carcinoma. Serum ANGPTL2 levels in patients negative for estrogen receptors and progesterone receptors, particularly triple-negative cases, reflected histological grades. Conclusions These findings suggest that serum ANGPTL2 levels in breast cancer patients could represent a potential marker of breast cancer metastasis.

scholarly journals Electrochemotherapy in the Treatment of Massive, Multisite Breast Cancer Metastasis to the Skin and Subcutaneous Tissue: A Case Report

Breast Care ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. 353-355 ◽  
Author(s):  
Mateusz Wichtowski ◽  
Paweł Potocki ◽  
Joanna Kufel-Grabowska ◽  
Joanna Streb ◽  
Dawid Murawa
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cancer Metastasis ◽  
Subcutaneous Tissue ◽  
Cancer Recurrence ◽  
Breast Cancer Metastasis ◽  
Locoregional Therapy ◽  
Non Invasive ◽  
Chest Wall Recurrence ◽  
Complete Clinical Remission

Background: Chest wall recurrence (CWR) from breast cancer after mastectomy is a difficult to treat disease. Electrochemotherapy (ECT) provides a safe, efficient, and non-invasive locoregional treatment approach in this setting. Case Report: A 61-year-old woman presented with unresectable breast cancer recurrence to the skin and subcutaneous tissue for which numerous lines of treatment were unsuccessful. Between February 2015 and May 2015, the patient underwent 3 courses of ECT after which a spectacular regression of the cutaneous metastatic foci was observed. After an overall observation period of 12 weeks, complete clinical remission was achieved. Conclusion: ECT can be proposed as an effective and safe locoregional therapy for breast cancer CWR and provides an alternative treatment modality to conventional therapies, especially in the case of multiple cutaneous and subcutaneous lesions.

scholarly journals A Case of 10-Year Survival after Adrenalectomy for Isolated Adrenal Metastasis of Breast Cancer

Reports ◽  
2020 ◽  
Vol 3 (3) ◽  
pp. 22
Author(s):  
Tsuyoshi Nakagawa ◽  
Goshi Oda ◽  
Akihiro Yano ◽  
Hiroshi Kawachi ◽  
Hiroyuki Uetake
Keyword(s):  
Breast Cancer ◽  
Hormone Therapy ◽  
Cancer Metastasis ◽  
Ductal Carcinoma ◽  
Radical Mastectomy ◽  
Breast Cancer Metastasis ◽  
Adrenal Metastasis ◽  
Pathological Examination ◽  
Endoscopic Adrenalectomy ◽  
Axillary Lymphadenectomy

Isolated adrenal metastasis of breast cancer is very rare, so adrenalectomy for breast cancer metastasis is rarely performed. The case of a breast cancer patient with five-year survival after resection of a left isolated adrenal metastasis is presented. A 70-year-old woman underwent left modified radical mastectomy and axillary lymphadenectomy for invasive ductal carcinoma (T2N1M0) 9 years earlier. At regular follow-up, a left adrenal mass, 4 cm in diameter, was seen on ultrasound examination and computed tomography (CT). Endoscopic adrenalectomy was performed. Pathological examination confirmed isolated adrenal metastasis of breast cancer. After surgery, hormone therapy was given for 5 years. Ten years after adrenalectomy, no metastatic lesions in other organs have been found on CT. Adrenalectomy for a metastatic adrenal tumor of breast cancer may provide survival benefits when combined with systemic hormone therapy and chemotherapy, particularly in patients with disease confined to the adrenal glands.

Sign in / Sign up

Export Citation Format

Share Document