ROLE OF CT SCAN OF PARANASAL AIR SINUSES FOR DIAGNOSTIC EVALUATION OF SINONASAL PATHOLOGY IN A TERTIARY CARE HOSPITAL IN EASTERN INDIA.

2021 ◽  
pp. 17-19
Author(s):  
Sk. Jishan Shine Alam ◽  
Swadha Priya Basu ◽  
Sayantan Roy ◽  
Md. Sajid

This study aims to evaluate the sensitivity and specicity of CT in diagnosis of sinonasal diseases along with the spectrum of Paranasal sinus diseases oncomputerized tomography (CT) and correlate their clinical and histopathological ndings. 40patients who have undergone endoscopic sinus surgery, their relevant histopathological and surgical reports are included in Radiodiagnosis department of Nil Ratan Sircar Medical College. Chronic sinusitis has 100% sensitivity,94% specicity, 96% positive predictive value (PPV) and 100% negative predictive value (NPV). For fungal sinusitis the sensitivity was 66%,specicity was 97.4%, PPV 66% and NPV 97.4%. Polyps have sensitivity of 90.9%, specicity of 94%, PPV 90% and NPV 100% Benign neoplasms have sensitivity of 100%, specicity of 100%, PPV 100% and NPV 100%. CT may be used as gold standardimaging modality for evaluating the PNS diseases.

Author(s):  
Prafulla Songara ◽  
Gaurav Saxena ◽  
Ramesh Agrawal

Chronic Rhinosinusitis is a common disorder, and its prevalence vary from 1-20% globally. The incidence of fungal sinusitis has increased to such extent in recent years that fungal infection is a common diagnosis in patients with Chronic Rhinosinusitis. The objectives of this current research were objectives of estimating the prevalence of Fungal aetiology in chronic sinusitis patients and their drug sensitivity pattern with common antifungal drugs. A total of 61 Cases present with Chronic Rhinosinusitis (CRS), visited in a tertiary care hospital based in Central Delhi, were included in our study. Excision of sinus tissue, including polyps and masses, were collected in the operation theatre during Functional Endoscopic Sinus Surgery (FESS) procedure in a sterile manner. All the tissues brought in sterile normal saline were processed for bacteriological and mycological examination. Tissues, obtained in 10% formalin were processed for histopathological and cytological analysis. A total of 14 (22.9%) cases of Chronic Rhinosinusitis were affected by fungal etiologies. By E test, the MIC range for isolates of Rhizopus arrhizus after 24 hr of incubation was 1-2 μg/mL, and the mean was 1.5 μg/Ml. Similarly, the MIC range for isolates of Aspergillus flavus after 48 hr of incubation was 0.5-16 μg/mL, and the mean was 4.09μg/mL. By the M38-A broth dilution method, the MIC range for the isolates of Rhizopus arrhizus after 24 hr of incubation was 0.5-2 μg/mL, and the mean was 1.25 μg/ml. Similarly, the MIC range for isolates of Aspergillus flavus after 48 hr of incubation was 0.5-4 μg/mL, and the mean was 1.95 μg/mL.


Author(s):  
Raghunath Shanbag ◽  
Santosh S. Garag ◽  
J. S. Arunkumar

<p class="abstract"><strong>Background:</strong> The objective of the study was to assess the role of corticosteroid given preoperatively in decreasing intraoperative bleeding during functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis.</p><p class="abstract"><strong>Methods:</strong> This is a retrospective study conducted in a tertiary care hospital for patients undergoing FESS for chronic rhinosinusitis from January 2016 to December 2016. In this study 120 patients of FESS were enrolled. Their data was analyzed for preoperative corticosteroid given and intraoperative grade of bleeding.  </p><p class="abstract"><strong>Results:</strong> There were 62 patients out of 120 who received preoperative corticosteroid. Among these 41 had grade 0-1 bleeding and 21 had grade 2-5 bleeding. Similarly in non-corticosteroid group 30 had grade 0-1 bleeding and 28 had grade 2-5 bleeding. Based on these p values was calculated using fisher exact test which showed that to be non-significant.</p><p class="abstract"><strong>Conclusions:</strong> Preoperative corticosteroids do not have control on intraoperative bleeding during FESS. They help in reducing the size of polyp and thus more effective in cases of CRSwNP.</p>


2013 ◽  
Vol 1 (1) ◽  
pp. 14-20
Author(s):  
O Bajracharya ◽  
PR Shankar ◽  
N Jha ◽  
A Banstola ◽  
R Shrestha ◽  
...  

Background and Objectives: Patient needs specific guidelines from their pharmacist in support of better compliance of their medicine used. Counseling of the patient and patient representative is important for improving the therapeutic out comes. Counseling patients can improve their understanding regarding medication, disease and life style modifications which in turn improves compliance. Material and Methods: Patients and/or patient party were counseled as per the Omnibus Budget Reconciliation Act-1990 guidelines. The data was collected as per OBRA-90 during the period of eighteen month and was analyzed using statistical software SPSS version 17. Results: Three hundred and fifty patients were counseled during the study period. Majority of the counseled patients were females [75.9%]. Mean counseling time taken by the pharmacist was 7.43 minute. Minimum time taken to counsel the patient was 6-10 minutes in 58.41% of the counseled, followed by less than 5 minutes in 19.68% and 11-15 minutes in 8.89%. About 10.47% were counseled for more than 15 minutes by the pharmacist. Greater numbers of the patients referred to the Medicine Counseling Center (MCC) were from Obstetrics and Gynecology departments and most of them were directed by doctors [50.47%]. Conclusion: This study highlights that role of doctor is important to encourage patient to attend counseling services. Counseling is the integral part that not only help patient to understand the use of their medicine but also to improve their therapeutic out comes. The effect of counseling on compliance should be studied in future. DOI: http://dx.doi.org/10.3126/jmcjms.v1i1.7881 Janaki Medical College Journal of Medical Sciences (2013) Vol. 1 (1):14-20


Author(s):  
Nikita Gandotra ◽  
Nivedita Prashar ◽  
Abhinav Sharma

Background: Infertility  has  always  been  one  of  the  most  elusive  symptom  complexes  that  perplex  the best gynecologists.  Amongst female factors, tubal factors are responsible for 25-30% of infertility. Hysterosalpingography and diagnostic laparoscopy with chromopertubation are widely used in the evaluation of tubal factors of infertility. Aim of the study was to compare hysterosalpingography and laparoscopy in the diagnosis of tubal patency in infertile patients.Methods: In this study 50 patients of infertility were evaluated prospectively in the Department of Obstetrics and Gynecology, Government Medical College, Jammu from April 2019 to March 2020. The findings of HSG and laparoscopy were compared.Results: Mean age at presentation for primary infertility was 28.6±4.20 years and for secondary infertility it was 32.1±3.84 years. Majority of patients of primary (77.6%) and secondary infertility (54.5%) had duration of infertility of 1-5 years in our study. The sensitivity of HSG was 90.91% and specificity was 77.78 % with positive predictive value of 83.33% and negative predictive value of 87.50%, when tubal pathology was defined as any form of tubal occlusion detected at laparoscopy, either one sided or two sided.Conclusions: HSG demonstrates high sensitivity in our study. So, it should be used as the initial investigation for identifying tubal patency. As the specificity is less, we suggest that laparoscopy is necessary to recognize those cases of tubal block which were unrecognized or wrongly recognized on HSG. In addition, the patients who were found to have tubal block on HSG, laparoscopy helps in finding the cause of infertility like existence of peritubal adhesions and endometriosis that can guide appropriate therapy.


Author(s):  
Vinod Kumar ◽  
Bhupen Songra ◽  
Richa Jain ◽  
Deeksha Mehta

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.


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