scholarly journals ASSESSMENT OF DRUG USAGE PATTERN IN PATIENTS OF ASTHMA: A CROSSSECTIONAL STUDY IN A TERTIARY CARE TEACHING HOSPITAL IN EASTERN INDIA

2020 ◽  
pp. 1-4
Author(s):  
Shambo Samrat Samajdar ◽  
Ritabrata Mitra ◽  
Manotosh Sutradhar ◽  
Debasish Ghosh ◽  
Mrinal Pal ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Usage Pattern ◽  
Utilization Pattern ◽  
Eastern India ◽  
Essential Drug ◽  
Drug Usage ◽  
Essential Drug List ◽  
Drug List ◽  
Rational Drug ◽  
Gina Guidelines

Background: In India, asthma imposes a substantial burden; though the disease still remains under-recognized, underestimated and under-treated in masses.With a global need of promoting rational drug use in healthcare, drug utilization pattern studies could provide feedback to prescribers and help in fostering rational drug usage. The present study was planned to study the drug utilization pattern in patients of asthma in a tertiary care set-up in eastern India and to evaluate it with respect to GINA guidelines. Materials and Methods: The study was carried out over a period of one year where cases with confirmed diagnosis of asthma, who gave informed consent to participate were included.Drug usage pattern was determined in the light of drugs prescribed, mean drugs per prescription, percentage of drugs prescribed in generic name and having conformation to national essential drug list. Percentage of inhalational, injectable, fixed dose combination and antibiotics per prescription were noted. Data were checked for completeness and statistically analysed. Results: The present study included 370 participants. A total of 1514 drugs were prescribed, with 4.09 drugs per prescription. 12.55% of drugs prescribed were from national essential drug list. A total of 1031 anti-asthma drugs were prescribed with 2.8 anti-asthma drugs per prescription. Among the various classes of anti-asthma drugs, maximum prescribed were inhalational corticosteroids, followed by long acting inhalational beta 2 agonist and anti-leukotriene drugs. 96.5% of total patients were on inhalational drugs, with budesonide and formeterol being majorly prescribed. Conclusion: The usage pattern as assessed in our study was in conformation to GINA guidelines. Guidelines like GINA have enlightened physicians about the rational prescribing in asthmatic patients.

scholarly journals Study of drug utilization pattern in emergency medicine ward at a tertiary care teaching hospital

2017 ◽  
Vol 6 (4) ◽  
pp. 868 ◽  
Author(s):  
Mamatha V. ◽  
Parashivamurthy B. M. ◽  
Suneetha D. K.
Keyword(s):  
Emergency Medicine ◽  
Drug Utilization ◽  
Wide Spectrum ◽  
Tertiary Care ◽  
Utilization Pattern ◽  
Essential Drug ◽  
Essential Drug List ◽  
Drug List ◽  
Drug Utilization Studies ◽  
Emergency Medicine Ward

Background: The emergency department represents an important platform for conducting drug utilization studies as patients present with a wide spectrum of diseases in acute form. An irrational prescription adversely affects the prognosis and recovery of patients. Hence, the objective of our study was to evaluate the drug utilization pattern and to determine the rationality of prescription using WHO prescribing indicators in emergency medicine ward.Methods: After obtaining Institutional Ethical Committee approval, a prospective observational study was conducted over 2 months. The case records of 150 patients admitted to the emergency medicine ward, with a hospital stay of more than 24hrs were reviewed to analyze the prescription pattern during the initial 48hrs of admission. Case records of patients irrespective of age, sex and diagnosis were included in the study. Descriptive statistics were used to analyze the results (SPSS version 20).Results: A total of 1014 drugs were prescribed from 150 case records with a mean age of 47±18 years. An average of 6.76 drugs was prescribed per prescription; percentage of encounters with at least an antimicrobial was 115 (76.66%). Injections were prescribed in all patients (100%) and only 416 (41.02%) drugs were prescribed by generic name and 657 (64.79%) drugs abided to the WHO essential drug list. Majority of patients received anti-ulcerogenic drugs followed by antimicrobials.Conclusions: There was a tendency of polypharmacy with overuse of PPIs and antimicrobials. There is need to rationalize the drug therapy in terms of increasing prescription of drugs from essential drug list by generic name.

Essential Drug List in a Rural Hospital

1987 ◽  
Vol 17 (4) ◽  
pp. 151-155 ◽  
Author(s):  
Bernt Lindtjørn
Keyword(s):  
Drug Prescription ◽  
Essential Drug ◽  
Drug Usage ◽  
Oral Rehydration ◽  
Essential Drug List ◽  
Southwestern Ethiopia ◽  
Drug List ◽  
Rational Drug ◽  
Rehydration Solution ◽  
One Year

An essential drug list was introduced to Gidole Hospital (Gamu Gofa Region, southwestern Ethiopia) in 1980. This study considers whether the introduction of the essential drug list improved drug prescription. Drug usage by admitted patients was examined retrospectively by drawing samples from two one-year periods (1979 and 1983/84). This study demonstrates that a change in drug prescription occurred: a significant decrease of non-essential and placebo drugs as well as vitamin injection was achieved. Oral rehydration solution (ORS) became the main treatment for diarrhoeal diseases, while other “diarrhoeal drugs” (8-hydroxyquinolines, bismuth opium and sulphaguanidine) were no longer used. Multidrug use was significantly reduced. It is concluded that the introduction of local drug lists creates an increased awareness of rational drug prescription.

scholarly journals Study on assessment of awareness about concepts in undergraduate pharmacology curriculum among clinicians in a tertiary care teaching hospital

2017 ◽  
Vol 6 (3) ◽  
pp. 633
Author(s):  
Rekha M. B. ◽  
Hemamalini M. B. ◽  
Basavaraj Bhandare
Keyword(s):  
Drug Use ◽  
Tertiary Care ◽  
Successful Implementation ◽  
Essential Drug ◽  
Text Book ◽  
Rational Drug Use ◽  
Essential Drugs ◽  
Essential Drug List ◽  
Drug List ◽  
Rational Drug

Background: Rational prescribing forms the corner stone of successful implementation of rational drug use. To boost the cause of rational use of Medicine, the P-drug concept was given in late nineties. The idea was to make Physicians familiar with few personal drugs chosen from National Essential drug list based on efficacy, safety, suitability and cost. The present study was conducted to assess the awareness of clinicians about basic pharmacological concepts.Methods: It is a cross sectional study with a study population of 100, conducted in RRMCH for a period of one month. It is a questionnaire based study involving clinicians and post graduates working in this hospital. Descriptive statistical analysis has been carried out in the present study.Results: In our study, 38% of physicians were aware of the term Essential drugs and 26% of doctors prescribed drugs from National Essential drug list. 56% of respondents were aware of term rational drug use but only 1/3 of them were aware of adverse effects, drug interactions of the drugs they prescribed. Majority of physicians (85%) used standard text book as the source of drug information.Conclusions: Lack of knowledge among physicians about new concepts like p-drug, rational drug use and essential drugs points towards need for having more CMEs on basic pharmacological concepts.

scholarly journals Drug Utilization Pattern by Using WHO Core Prescribing Indicators in Orthopedics and Obstetrics / Gynecology Departments of a Tertiary Care Hospital

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Naresh Karki ◽  
Ruban Raj Joshi ◽  
Buddhi Kumar Shrestha ◽  
Pravin Prasad
Keyword(s):  
Drug Utilization ◽  
Low Income ◽  
Tertiary Care ◽  
Care Hospital ◽  
Utilization Pattern ◽  
Essential Drug ◽  
Prescribing Indicators ◽  
Essential Drug List ◽  
Drug List ◽  
Prescription Form

Introduction: Drug utilization research is an important tool to facilitate rational use of drugs. In low income countries irrational use of drugs is a common problem like overuse of drugs and inappropriate use of antibiotics, leading to poor treatment outcome and increased burden of treatment. This study was conducted to provide understanding of drug utilization pattern by using WHO Core Prescribing Indicator. Methods: This study was conducted in Orthopedics and Obstetrics / Gynecology departments. Patients visiting these Out Patient Departments with at least one drug on prescription form were included in the study. Further, information related to WHO Core Prescribing Indicators were collected in pre-designed proforma. Results: Average number of drugs prescribed per prescription was 2.6. Means of number of drugs prescribed in Orthopedics and Obstetrics / Gynecology departments were 2.9 and 2.3 respectively (p < 0.001). Drugs prescribed in generic name and from essential drug list was 41.4% and 34.3% respectively. Prescription forms with generic name in Orthopedics department were significantly more compared to Obstetrics / Gynecology department (p = 0.00002). However, there was an increased tendency to prescribe drugs from essential drug list in Obstetrics / Gynecology department compared to Orthopedics department (p < 0.001). Conclusion: Drugs were prescribed by generic name and from essential drug list, but this was not sufficient to meet the ideal values of WHO Core Prescribing Indicator. Therefore, prioritization on prescribing drugs by generic name and from essential drug list by respective departments to achieve the standards of WHO needs to be encouraged.

scholarly journals Evaluation of rational drug use pattern using WHO prescribing indicators in a medical intensive care unit of a tertiary teaching hospital in Kerala, India

2017 ◽  
Vol 6 (6) ◽  
pp. 1328
Author(s):  
Shobha P. ◽  
Messaline Sunitha
Keyword(s):  
Tertiary Care ◽  
Care Hospital ◽  
Prescribing Practices ◽  
Essential Drug ◽  
Prescribing Pattern ◽  
Respiratory Problems ◽  
Essential Drug List ◽  
Drug List ◽  
Tertiary Teaching ◽  
Set Up

Background: ICU patients are exposed to more number of life saving drugs and face drug related problems like therapeutic failure, drug interactions and frequent adverse drug reactions. The cost of ICU hospitalisation and money spent on medicines is also a huge burden on these patients. A study of prescribing pattern in an ICU set up will serve as a medical audit to monitor and evaluate the prescribing practices to make it more rational and cost effective.Methods: A prospective observational study was carried out in a medical ICU of a tertiary care hospital. All the inpatients admitted in the medical ICU during the study period of 2 months were included in the study. The data obtained from the case sheets were used to assess the prescribing pattern and rationality of drug use.Results: A total of 101 patients were admitted in 2 months. The most common illness for which the patients (22) were admitted was respiratory problems. Average number of drugs per prescription was 6.9. Cardiovascular system (23.9%) drugs were the most frequently prescribed. Pantoprazole (77) was the single most commonly prescribed drug. 40% of the drugs were prescribed from the essential drug list. The average cost of medicines incurred per person in our study was 5126.33 in INR.Conclusions: Polypharmacy and unwanted prescription of proton pump inhibitors can be avoided by prescribing more generics and drugs from essential drug list.

scholarly journals The Assessment of Drug Utilization Study of Anticancer Drugs Using WHO Prescribing Indicators in a Government Tertiary Care Hospital of the Hyderabad - Karnataka Region of India

2019 ◽  
Vol 7 (7) ◽  
pp. 1203-1208 ◽  
Author(s):  
Asmatanzeem Bepari ◽  
Nayana Sakre ◽  
Ishrat Rahman ◽  
Shaik Kalimulla Niazi ◽  
Asmabi M. Dervesh
Keyword(s):  
Anticancer Drugs ◽  
Anticancer Agents ◽  
Tertiary Care ◽  
Inappropriate Drug ◽  
Care Hospital ◽  
Essential Drug ◽  
Prescribing Indicators ◽  
Rational Use ◽  
Essential Drug List ◽  
Drug List

BACKGROUND: Cancer is a major burden and threat to global society. A wide range of chemotherapeutic agents is extensively used to treat cancer at different stages. Inappropriate drug use may also lead to the raised cost of medical care, adverse drug effects, and patient mortality. Hence, in recent years, drug utilisation studies have become a potential tool to be used in the evaluation of different health care systems including cancer. AIMS: The objectives of the study were to identify the various types of cancer, the commonly prescribed drugs, rational use of anticancer drugs, and analyse the prescribing indicators in a tertiary care government hospital of India. MATERIAL AND METHODS: Newly diagnosed cancer and/or known case of carcinoma of either sex which required treatment/on treatment with chemotherapy aged > 18 yrs admitted in Radiotherapy Department from April 2016 to September 2016 were included in the study and analysed for prescribing indicators. RESULTS: The head & neck cancers were the prevalent cancers observed with more preponderance among males. Most of the patients were prescribed with a single anticancer drug. Cisplatin was the most commonly used cytotoxic drug followed by carboplatin, and antimetabolites. The most commonly used adjuvant drugs in our study were anti-emetics and anti-peptic ulcer drugs. Over 82% of anticancer agents were taken from the essential drug list and were prescribed in generic names, indicating rational use. CONCLUSION: Over 82% of anticancer agents were taken from the essential drug list and were prescribed in generic names, indicating rational use.

scholarly journals A Study of drug utilization pattern in gynaecology out-patient department of a tertiary care hospital

2019 ◽  
Vol 7 (11) ◽  
pp. 4280
Author(s):  
Manish B. Nandeshwar ◽  
Ashish D. Chakravorty
Keyword(s):  
Drug Utilization ◽  
Rural Areas ◽  
Demographic Data ◽  
Tertiary Care ◽  
Brand Names ◽  
Care Hospital ◽  
Essential Drug ◽  
Essential Drug List ◽  
Drug List ◽  
Patient Department

Background: Gynaecological diseases are common in India because of socioeconomic, hygienic and literacy problems. Gynaecological drugs are one of the strong selling drugs in pharmaceutical market. Drug utilization research facilitate appropriate use of drugs in patient, minimize the adverse event and lead to better patient outcome. So, the present study was carried out to examine the patterns of drug prescription.Methods: A retrospective, observational study was done by collecting the prescriptions of the patients who attended the Gynaecology out-patient department in our institute for the period of six months. Total 300 prescription were collected and analysed. Patient’s demographic data, total number and category of drugs prescribed, percentage of individual drug and their dosage forms, drugs prescribed by generic name, brand names and percentage of drugs prescribed from essential drug list were analysed.Results: The mean age of presentation was 36.6±10.98 years. Among infective group breast abscess were common and among non-infective cases dysmenorrhea was most common. Out of 754 drugs prescribed, minerals were most commonly prescribed (42.70%) followed by antimicrobials (24.53%). Tablet form were prescribed more commonly (96.02%) followed by capsules (2%) and injections (1.06%). The average no. of drugs per prescription was 2.51±1.26 SD. Percentage of drugs prescribed by generic name were 98.01% and drugs prescribed from essential drug list were 85.41%.Conclusions: The overall drug use pattern in our study correlates with various gynaecological diseases. Majority of the women from rural background depend on primary health services for gynaecological diseases in their areas so, strengthening of gynaecological health care services reduce the morbidity among the women from rural areas. 

scholarly journals Prescribing patterns in primary and secondary level government health facilities in a district of Assam: a cross sectional study

2019 ◽  
Vol 6 (5) ◽  
pp. 2077
Author(s):  
Dakshadhwari Upadhyay ◽  
Rashmi Ahmed ◽  
Rupali Baruah ◽  
Manjit Boruah
Keyword(s):  
Drug Use ◽  
Secondary Level ◽  
Cross Sectional Study ◽  
Prescribing Patterns ◽  
Essential Drug ◽  
Cross Sectional ◽  
Essential Drug List ◽  
Drug List ◽  
Rational Drug ◽  
Level Government

Background: Indian markets are flooded with more than 100,000 formulations, compared to approximately 350 formulations listed in the World Health Organization (WHO) essential drug list. To promote rational drug use in developing countries, assessment of drug use patterns with the WHO drug use indicators is becoming increasingly necessary. This study was conducted to study the prescribing patterns using WHO prescribing indicators in government healthcare facilities in a district of Assam.Methods: This was a cross sectional study carried out from July to September 2017. Out of total 4 blocks in Tinsukia district one (Ketetong) was randomly selected. All the primary and secondary level government health facilities were included and visited one by one. All the prescriptions on that day of visit were digitally photographed at the pharmacy of the health institution after taking written informed consent from the patient. A total of 353 prescriptions were scrutinized and analyzed using appropriate statistical tests.Results: Out of total 353 prescriptions collected, 11 were illegible and excluded from the analysis. The average number of drugs per encounter was 3.8. In 62.3% of encounters antibiotics were prescribed and injections were prescribed in 30.1% encounters. 71.8% drugs were prescribed by generic name and 56.2% drugs were prescribed from the essential drug list (EDL).Conclusions: The average number of drugs, percentage of injections and antibiotics per encounter was higher than recommended whereas prescription by generic name and from EDL or formulary was lower than recommended. Training of healthcare workers on rational drug use is need of the hour.

scholarly journals Prescribing Practices in the Outpatient Department in a Tertiary Care Teaching Hospital in Bangladesh

2013 ◽  
Vol 2 (2) ◽  
pp. 13-17
Author(s):  
Mohammad Afsan ◽  
Muhammad Mahbubul Alam ◽  
Nushrat Noor ◽  
AH Hamid Ahmed
Keyword(s):  
Intervention Program ◽  
Generic Drugs ◽  
Tertiary Care ◽  
Inappropriate Prescribing ◽  
World Health ◽  
Prescribing Practices ◽  
Essential Drug ◽  
College Hospital ◽  
Essential Drug List ◽  
Drug List

A cross-sectional descriptive study was carried out among individuals attending the Out Patient Department (OPD) of Medicine, Paediatrics, Dermatology & Venerology, ENT, Orthopaedics and Gynaecology & Obstetrics from December 2011 to March 2012 in East-West Medical College Hospital, Dhaka, Bangladesh, to see the patterns of prescriptions using World Health Organization (WHO) core prescribing indicators and some additional indices. A total of 300 prescriptions were collected and analyzed by the 3rd year MBBS students in this study. The average number of drugs per encounter was 3.22 and 5.33% drugs were prescribed by generic name. Use of antibiotic (48.67% of encounters) was frequent, but injection use (6.67% of encounters) was within the recommendation of WHO. Only 26.09% drugs were prescribed from national essential drug list. Percentage of encounters with a NSAID, an anti-ulcerant, an antihistamine, a calcium preparation and a multivitamin & multimineral prescribed were 44.33%, 43.33%, 22.33%, 19.33% and 15.67% respectively. So, the findings from current study showed a trend towards inappropriate prescribing, particularly the over-prescribing of antibiotics and under-prescribing of generic drugs and also most of the drugs were prescribed out of national essential drug list. Hence, there would be needed for effective intervention program to encourage the physicians and healthcare providers in promoting more appropriate drug use. DOI: http://dx.doi.org/10.3329/updcj.v2i2.15483 Update Dent. Coll. j: 2012; 2 (2): 13-17

scholarly journals Pattern of drug prescription for the treatment of falciparum malaria in a medical college in Eastern India

2016 ◽  
Vol 7 (4) ◽  
pp. 80-83
Author(s):  
Pratyay Pratim Datta ◽  
Anju Prasad ◽  
Chaitali Pattanayak ◽  
Ashok Singh Chouhan ◽  
Parbaty Panda
Keyword(s):  
Falciparum Malaria ◽  
Drug Cost ◽  
Drug Prescription ◽  
Tertiary Care ◽  
Essential Drug ◽  
Prescription Pattern ◽  
Medical College ◽  
Essential Drug List ◽  
Drug List ◽  
Sizable Proportion

Background: Drug prescription pattern for the treatment of falciparum malaria differs widely from place to place; but there is also some intra organizational variation of prescription pattern of anti-malarial drugs for the treatment of falciparum malaria.Aims and Objectives: The present study was planned to study the drug utilization pattern for the treatment of falciparum malaria in a tertiary care teaching hospital in eastern India.Materials and Methods: It was a hospital based study conducted in the department of medicine among the patients admitted with confirmed diagnosis of falciparum malaria. Drugs prescribed, average number of drugs per prescription, percentage of drugs prescribed in generic name, percentage of prescription with co-prescription of antibiotics, percentage of prescription having at least an injection prescribed, percentage of drugs prescribed from essential drug list or formulary and average drug cost per prescription are the parameters studied in this study.Results: Average number of drugs per prescription in the present study was 3.96. Artesunate and Mefloquine were the most common anti-malarial drugs prescribed among study subjects. 22.9% patients received oral Chloroquine as anti-malarial drug. 43.3% prescriptions had antibiotics co-prescribed. Only 16.9% drugs were prescribed in generic name. 85.4% of the prescribed drugs were from essential drug list. Average drug cost per patient was Rs. 282/- with minimum of Rs. 55/- and maximum of Rs. 1750/-.Conclusion: Though Artesunate combination therapy is getting popularized gradually but a sizable proportion of patients (22.9%) were prescribed with oral Chloroquine therapy. Generic prescription of drugs should be encouraged among the physicians. Multi-centric study regarding drug prescription can give a broader picture in changing scenario.Asian Journal of Medical Sciences Vol.7(4) 2016 80-83

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