ROLE OF DOXYCYCLINE IN COVID-19- A REVIEW

2021 ◽  
pp. 7-8
Author(s):  
Jayasheela. J ◽  
Aqsa Qureshi.AF ◽  
Somasundaram. G
Keyword(s):  
Lung Cancer ◽  
Health Hazard ◽  
Antiviral Agents ◽  
Autoimmune Disorders ◽  
The Novel ◽  
Pulmonary Infections ◽  
Potential Threat ◽  
Infection Treatment ◽  
Timely Treatment

The novel SARS-coV-2 is a potential threat and health hazard mostly for people already suffering from pulmonary infections such as lung cancer, any autoimmune disorders, etc. This poses a threat in every phase of the infection. Treatment with some antiviral agents such as remdesivir may prove to be useful but their increased level of toxicity makes them quite unfavourable. Use of drugs like doxycycline which have gone through the process of providing timely treatment and better results in diseases such as chikungunya and dengue, than resorting to only anti-viral drugs, has proven to be more helpful

SARS-COV2 virus and Coronavirus disease (COVID-19)

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 977-982
Author(s):  
Mohamed J. Saadh ◽  
Bashar Haj Rashid M ◽  
Roa’a Matar ◽  
Sajeda Riyad Aldibs ◽  
Hala Sbaih ◽  
...  
Keyword(s):  
Close Contact ◽  
Antiviral Agents ◽  
Health Concern ◽  
The Novel ◽  
Global Public Health ◽  
Fatal Disease ◽  
Mild Disease ◽  
Life Threatening ◽  
Novel Coronavirus

SARS-COV2 virus causes Coronavirus disease (COVID-19) and represents the causative agent of a potentially fatal disease that is of great global public health concern. The novel coronavirus (2019) was discovered in 2019 in Wuhan, the market of the wet animal, China with viral pneumonia cases and is life-threatening. Today, WHO announces COVID-19 outbreak as a pandemic. COVID-19 is likely to be zoonotic. It is transmitted from bats as intermediary animals to human. Also, the virus is transmitted from human to human who is in close contact with others. The computerized tomographic chest scan is usually abnormal even in those with no symptoms or mild disease. Treatment is nearly supportive; the role of antiviral agents is yet to be established. The SARS-COV2 virus spreads faster than its two ancestors, the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower fatality. In this article, we aimed to summarize the transmission, symptoms, pathogenesis, diagnosis, treatment, and vaccine to control the spread of this fatal disease.

scholarly journals The role of radiation therapy in the management of small cell lung cancer

Breathe ◽  
2017 ◽  
Vol 13 (4) ◽  
pp. e87-e94 ◽  
Author(s):  
Markus Glatzer ◽  
Sabine Schmid ◽  
Marco Radovic ◽  
Martin Früh ◽  
Paul Martin Putora
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Aggressive Form ◽  
Palliative Setting ◽  
Timely Treatment

Small cell lung cancer (SCLC) is a very aggressive form of lung cancer. SCLC treatment requires multidisciplinary management and timely treatment. Radiation therapy is an important part of management of all stages of SCLC, in the curative as well as in the palliative setting. The role of radiation therapy in all stages of SCLC has changed in recent years; this article describes these changes and highlights the role of radiation therapy in the management of SCLC.

scholarly journals The Novel Role of the Mu Opioid Receptor in Lung Cancer Progression

2011 ◽  
Vol 112 (3) ◽  
pp. 558-567 ◽  
Author(s):  
Biji Mathew ◽  
Frances E. Lennon ◽  
Jessica Siegler ◽  
Tamara Mirzapoiazova ◽  
Nurbek Mambetsariev ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Opioid Receptor ◽  
Cancer Progression ◽  
Mu Opioid Receptor ◽  
The Novel ◽  
Mu Opioid

scholarly journals Novel Corona Virus (COVID-19): Current Strategies and Future Aspects

2021 ◽  
Vol 11 (4) ◽  
pp. 4201-4212
Keyword(s):  
Efficient Solutions ◽  
Current Therapy ◽  
Clinical Aspects ◽  
Human Society ◽  
The Novel ◽  
Potential Threat ◽  
Virus Structure ◽  
Novel Coronavirus ◽  
Improve Patient

Novel coronavirus (COVID-19) recently emerged as a new pandemic disease that affects millions of people worldwide. This disease considers as a potential threat to human society. Researchers are continuously working to identify virus structure, the pathophysiology of the disease, and possible treatment of the disease. Currently, to fight against the coronavirus, two major strategies have been adopted throughout the world; one is to target virus-cell machinery, and the second is to improve patient immunity. In this review, we have described detailed information about the structure and life cycle of the novel coronavirus, current therapy, and future strategies to fight against this pandemic disease. Computational methods are useful for understanding virus structure, disease pathology, and discovering novel anti-COVID agents. These methods can provide fast and efficient solutions to fight against this disease. We also highlighted the potential role of robotic technology and its importance in various clinical aspects. These robotic technologies may also play an important role in fighting COVID-19.

scholarly journals Molecular Mode of Action and Role of TP53 in the Sensitivity to the Novel Epothilone Sagopilone (ZK-EPO) in A549 Non-Small Cell Lung Cancer Cells

PLoS ONE ◽  
2011 ◽  
Vol 6 (4) ◽  
pp. e19273 ◽  
Author(s):  
Sebastian Winsel ◽  
Anette Sommer ◽  
Julia Eschenbrenner ◽  
Kevin Mittelstaedt ◽  
Ulrich Klar ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Mode Of Action ◽  
Small Cell ◽  
The Novel ◽  
Small Cell Lung ◽  
Molecular Mode

scholarly journals Prolonged Nitric Oxide Exposure Enhances Anoikis Resistance and Migration through Epithelial-Mesenchymal Transition and Caveolin-1 Upregulation

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Pithi Chanvorachote ◽  
Varisa Pongrakhananon ◽  
Preedakorn Chunhacha
Keyword(s):  
Nitric Oxide ◽  
Lung Cancer ◽  
Cancer Cells ◽  
Epithelial Mesenchymal Transition ◽  
The Novel ◽  
Anoikis Resistance ◽  
Mesenchymal Transition ◽  
Caveolin 1 ◽  
And Migration

Nitric oxide (NO) in tumor microenvironment may have a significant impact on metastatic behaviors of cancer. Noncytotoxic doses of NO enhanced anoikis resistance and migration in lung cancer H23 cells via an increase in lamellipodia, epithelial-mesenchymal transition (EMT) markers including vimentin and snail, and caveolin-1 (Cav-1). However, the induction of EMT was found in Cav-1-knock down cells treated with NO, suggesting that EMT was through Cav-1-independent pathway. These effects of NO were consistently observed in other lung cancer cells including H292 and H460 cells. These findings highlight the novel role of NO on EMT and metastatic behaviors of cancer cells.

The role of surgery in the cure of lung cancer

1967 ◽  
Vol 120 (2) ◽  
pp. 168-175 ◽  
Author(s):  
K. R. Boucot
Keyword(s):  
Lung Cancer
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