A STUDY ON HUMAN CADAVERIC PANCREAS: VARIATIONS IN DIAMETERS OF ISLETS OF LANGERHANS IN DIFFERENT AGE GROUP

2021 ◽  
pp. 18-21
Author(s):  
Baro Baneswar ◽  
Rabha Gunamani ◽  
Sarma Usha ◽  
Talukdar KL ◽  
Dutta BC ◽  
...  
Keyword(s):  
Islets Of Langerhans ◽  
Body Part ◽  
Cross Sectional Study ◽  
Head Part ◽  
Human Pancreas ◽  
Tail Region ◽  
Cross Sectional ◽  
Medical College ◽  
Tail Part ◽  
C 30

INTRODUCTION: The islets of Langerhans may contain a few cells or many hundreds of polygonal cells arranged in short irregular cords that are abundantly invested with a network of fenestrated capillaries to produce a hormone with glucose-lowering effect. MATERIALS AND METHODS: The descriptive and cross-sectional study was done in the Department of Anatomy, Forensic Medicine& Pathology of Gauhati Medical College, Guwahati based on collection of 103 human pancreas aging from 13 to 78 years of both sexes.The collected samples were divided into group A (10-19 years),B (20-29 years),C (30-39 years),D (40-49 years),E (50-59 years),F (60-69 years) and G (≥70 years).Measurement of five slides selected from head, body and tail region were examined under 400 magnification. RESULTS AND OBSERVATION:The differences between the diameter of pancreatic islets for head part were statistically significant in A vs B,A vs D,A vs E,A vs F,A vs G,B vs D,B vs E,B vs F,B vs G, C vs E,C vs F,C vs G,F vs G in body part A vs B,A vs C,A vs F, A vs G,B vs C,B vs D,B vs E,B vs F,B vs G,C vs G,D vs G,E vs G and F vs G.and in tail part between A vs B,A vs C,A vs D,A vs E, A vs F, A vs G, B vs C, B vs D, B vs E, B vs G, C vs E, C vs F, C vs G, D vs F, D vs G, E vs F , E vs G and F vs G region. CONCLUSIONS:In the 3 region it was found that in the both extremities of life the diameter of islets of Langerhans was gradually decreased as age increases. Larger samples and advanced procedures in case of normal and abnormal population like people with diabetes disease for further studies may recommended.

scholarly journals A MORPHOMETRIC STUDY ON HUMAN CADAVERIC PANCREAS IN ASSAMESE POPULATION

2020 ◽  
pp. 15-18
Author(s):  
Baro Baneswar ◽  
Sarma Usha ◽  
Talukdar KL ◽  
Dutta BC ◽  
Sarma Tapan ◽  
...  
Keyword(s):  
Correct Diagnosis ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Morphometric Study ◽  
Clinical Settings ◽  
Human Pancreas ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
C 30

The seriousness of pancreatic diseases and the utmost importance of its correct diagnosis and treatment are expected to be helpful in correlating the functional capacity for further study in basic science and in decision making in clinical settings especially in transplant surgery of pancreas. Knowledge of normal morphometry of pancreas in living subjects is essential for understanding the segmental resection of pancreas as well as pancreatic imaging. A descriptive and cross-sectional study was conducted in the Department of Anatomy, Forensic Medicine & Pathology of Gauhati Medical College, Guwahati from May, 2016 to December 2019 on 103 specimens of human pancreas from 13 to 78 years age of both sexes. The collected samples were divided into seven age groups: A (10-19 years), B (20-29 years), C (30-39 years), D (40-49 years), E (50-59 years), F (60-69 years) and G (≥70 years), for convenient description. The differences between length of pancreas were statistically significant in A vs C, A vs D, A vs E, A vs F, A vs G, B vs C, B vs D, B vs E, B vs F and B vs G. The differences between weight of pancreas were statistically significant in A vs F, B vs C, B vs G, C vs D, C vs F, D vs F, E vs F, E vs G and F vs G. The present study is expected to standardize the morphology of pancreas in Assamese population.

scholarly journals Histomorphometric Changes of Pancreatic Islets with Advancing Age – A Postmortem Study in A Bangladeshi Male Population

2014 ◽  
Vol 3 (1) ◽  
pp. 63-67
Author(s):  
S Shahriah ◽  
ASM Nurunnabi ◽  
GN Begum ◽  
R Kabir
Keyword(s):  
Pancreatic Islets ◽  
Islets Of Langerhans ◽  
Unit Area ◽  
Age Groups ◽  
The Body ◽  
Human Pancreas ◽  
Tail Region ◽  
Male Population ◽  
Cross Sectional ◽  
Group A

Background: We proposed this study to see the difference in number and diameter of the islets of Langerhans of the pancreas with increasing age in Bangladeshi males, as male population is more prone to diabetes mellitus than female. Methods: This cross-sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from August 2005 to December 2006, based on collection of 75 postmortem male human pancreas. The collected samples were divided into seven age groups: A (10-19 years), B (20-29 years), C (30-39 years), D (40-49years), E (50-59 years), F (60-69 years) and G (≥70 years). In histological slides, number of islets of Langerhans was measured by point counting technique per unit area of microscopic field and diameter by using ocular and stage micrometer. Results: The number of islets per unit area of the head of the pancreas were 1.40±0.55, 1.80±0.45, 1.40±0.55, 1.00±0.00, 1.80±0.45, 1.00±0.00and 1.20±0.45; in the body 1.20±0.45, 2.40±0.45, 2.00±0.00, 2.50±0.55,2.40±8.90, 2.20±0.45 and 2.00±0.00; in the tail region 2.40±0.55,3.00±1.22, 2.40±1.34, 2.80±0.84, 3.00±1.22, 2.80±0.84 and 3.20±0.45 in group A, B, C, D, E, F and G respectively. The diameter of pancreatic islets were found 82.64±0.73μm, 96.32±0.91μm, 108.52±8.76μm,135.20±8.38μm, 134.36±4.46μm, 102.40±0.89μm and 97.20±2.00μm in group A, B, C, D, E, F and G respectively. Conclusion: The number of the islets was much higher in tail than that of other regions. However, the diameter of the islets was found to increase up to 49 years and later decreased. Nepal Journal of Medical Sciences | Volume 03 | Number 01 | January-June 2014 | Page 63-37 DOI: http://dx.doi.org/10.3126/njms.v3i1.10361

Side Effects of Chemotherapy and Cancer Treatment in Tertiary Care Teaching Hospital

2016 ◽  
Vol 2 (1) ◽  
pp. 62-78
Author(s):  
. Hemraj ◽  
Raj Kumar ◽  
Sourabh Kosey ◽  
Amit Sharma ◽  
Nalini Negi
Keyword(s):  
Side Effects ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Informational Needs ◽  
Cross Sectional ◽  
Clinical Pharmacists ◽  
Medical College ◽  
Related Information ◽  
The Common ◽  
Chemotherapy Patients

To determine the most common physical side effects experienced by local chemotherapy patients. Their perceptions of these side effects and informational needs from clinical pharmacists were also evaluated. This was a single center, observational cross-sectional study conducted at department of General Surgery, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab. A face to face interview was conducted. Information collected included chemotherapy related side effects after last chemotherapy experience, the most worrisome side effects, overlooked by healthcare professionals and the preferred method, amount and source of receiving related information. In this study, hundred patients were enrolled out of them 48 were male and 52 were female. When differential calculations was done, common side effects or adverse effects of chemotherapy in the patients of breast, lung cancer, Ovarian Cancer, Colon cancer, Prostate cancer, Lymphoma Cancer, Cervix cancer where there is much irregular medicine intake 57.4% may be due to common problem of joint pain reported by all the patients under study, with the consecutive problem of nausea and vomiting. The high prevalence of chemotherapy related side effects among local patients is a major concern and findings of their perceptions and informational needs may serve as a valuable guide for clinical pharmacists and physicians to help in side effect management. This study shows the common problems reported by the patients when they are suffering from cancer condition, according to their incidence perceptions as experienced by the patient, this will allow the physician and clinical pharmacist to effectively counsel and manage the common symptoms as reported prior to its occurrence in the patient, so that withdrawal can be checked.

Rapid detection of Rotavirus antigen in stool sample of acute diarrheic children

2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun
Keyword(s):  
Stool Sample ◽  
Rapid Detection ◽  
Cross Sectional Study ◽  
Rapid Diagnosis ◽  
Age Group ◽  
College Hospital ◽  
Cross Sectional ◽  
Rotavirus Infection ◽  
Medical College ◽  
Stool Samples

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13

Suicidal Death Autopsy Analysis at Dhaka Medical College

1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter
Keyword(s):  
Forensic Medicine ◽  
Causes Of Death ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Autopsy Report ◽  
Common Causes ◽  
Suicidal Death

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21

Comparison of Heffner Criteria and Light Criteria in Differentiating Exudative and Transudative Pleural Effusion

2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta
Keyword(s):  
Pleural Effusion ◽  
Cross Sectional Study ◽  
Pleural Space ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
The Common ◽  
The Mean ◽  
Exudative Pleural Effusion

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.

Perceptions of Final Year Medical Students about Family Medicine as A Career Choice in Pakistan

2020 ◽  
Author(s):  
Dur-e- Nishat
Keyword(s):  
Medical Students ◽  
Family Medicine ◽  
Medical Profession ◽  
Healthcare Services ◽  
Developed Countries ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Medical College ◽  
Chi Square Test

Background: Family medicine is a field in which complete and detailed set of healthcare services are provided to the patients and their families. In developed countries, freshly graduated students choose family medicine as a priority for their career. However, in Pakistan it is not the case. The present study is undertaken to determine the perceptions of final year medical students’ about Family Medicine as a viable career. Methods: A total number of 504 students participated in the study. This was a cross-sectional study. The study participants were in their final year of medical college. Data was collected using a preapproved questionnaire. Data was entered and analyzed via SPSS version 17 and Chi-Square test was used post-stratification. Results: Only 14.3% (n=72) medical students had heard about Family Medicine. Only 18% (n=92) would select family medicine as a profession. The most frequent rationale for choosing the field of Family Medicine was the variety of patients seen in general practice (55.4% n=51). Conclusion: There is a dire need to focus on increasing awareness about the field of family medicine among medical students. The students should be counseled on the advantages along with the disadvantages of choosing this field as a medical profession.

To Study the Clinical Profile and Management of Cellulitis of Lower Limb in Northern India

2021 ◽  
pp. 153473462098667
Author(s):  
Tripta S. Bhagat ◽  
Luv Kumar ◽  
Prakhar Garg ◽  
Apoorv Goel ◽  
Amit Aggarwal ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Lower Limb ◽  
Surgical Intervention ◽  
Significant Risk ◽  
Cross Sectional Study ◽  
Common Complication ◽  
Cross Sectional ◽  
Medical College ◽  
Northern India ◽  
Working Age

Cellulitis is a bacterial infection of the dermis and subcutaneous tissues occupying a large proportion of hospital beds. This study was conducted for analysis of patients with cellulitis according to their demographics and clinical presentation and to examine their comorbidities, complications, and its management. This observational cross-sectional study was conducted in the Department of Surgery at Santosh Medical College and Hospitals involving a total of 60 cases having cellulitis and other soft tissue infections of lower limb. Analysis of their demographic profile, management, and complications was done. Cellulitis is seen commonly in males, 46 (76.6%). The mean age of patients affected by cellulitis in the study was 36.4 ± 1.23 years. The most common site affected is leg involving more people in field jobs. The most common risk factor was trauma in 46.6%, and other factors were diabetes mellitus and smoking, while abscess formation was the most common complication observed in 36.6% of cases. A total of 56.6% cases were managed conservatively, while 43.3% cases required surgical intervention. Mean hospital stay in this study was 5.02 ± 0.23 days. It was concluded that cellulitis is subcutaneous, spreading bacterial infection is more common in males, and its incidence is highest in working age group population. Lower limb is commonly involved. Trauma, smoking, and diabetes are significant risk factors for development of cellulitis. Abscess is the most common complication. About 50% patients with cellulitis can be managed conservatively and the rest require surgical intervention.

scholarly journals Prevalence of Urinary Incontinence in Women

2020 ◽  
Vol 33 (1) ◽  
pp. 59-62
Author(s):  
Lubna Yasmin ◽  
Ferdousi Begum
Keyword(s):  
Urinary Incontinence ◽  
Stress Incontinence ◽  
Urge Incontinence ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mixed Incontinence ◽  
Medical College

Objective: The objectives of the study were to find out the prevalence of urinary incontinencein women. Materials and Methods: A cross sectional study was conducted on five hundred one (501)women older than 18 years of age who were admitted in department of obstetrics andgynaecology of Shaheed Suhrawardi Medical College and Hospital from April to December2009, answered a questionnaire about urinary incontinence. They were grouped accordingto presence or absence of urinary incontinence (incontinent and continent) and type ofincontinence present (urge, stress and mixed). Results: Urinary incontinence was found in 104(20.8%) women, out of which 25 (24%)suffered from stress incontinence only, 21 (20.2%) suffered from urge incontinence and58(55.8%) suffered mixed incontinence. Conclusions: One in five women older than 18 years of age suffer from one or other formof urinary Incontinence. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 59-62

Knowledge, Attitude and Practices of Pharmacovigilance among Doctors at a Tertiary Care Teaching Hospital Birgunj, Nepal

Med Phoenix ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 14-18
Author(s):  
Smita Singh ◽  
Deependra Prasad Sarraf ◽  
Prabin Singh ◽  
Pragati Poudyel
Keyword(s):  
Teaching Hospital ◽  
Health Care Professionals ◽  
Tertiary Care ◽  
College Teaching ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Medical College ◽  
National Medical

Introduction: Pharmacovigilance helps in the detection and prevention of adverse effects of drugs. For the effectiveness of this program, health care professionals should report adverse drug reactions (ADRs) considering it as their moral and professional obligation. The objective of the study was to assess the knowledge, attitude, and practices (KAP) of the doctors towards ADRs and pharmacovigilance in  National Medical College Teaching Hospital (NMCTH), a tertiary care teaching hospital situated in the Narayani zone. Materials and Methods: A cross-sectional study was carried out using a self-administered questionnaire consisting of four parts; first part included a demographic profile of participants, the second part consisted of ten questions for the assessment of the knowledge about pharmacovigilance, third part comprised of six questions on attitude and fourth part consisted of five questions on practice. The results were depicted in the form of percentages for each KAPs questionnaire.   Results: The response rate of participants was 85.16%. Pharmacovigilance was correctly defined by 52%. Department of drug administration was responsible for monitoring ADRs in Nepal was correctly given by 80%. Only 8% had reported ADRs, although 62% had encountered an ADR in their clinical practice. Conclusion: The doctors at NMCTH had a poor KAP towards pharmacovigilance and educational intervention is needed for the proper functioning of this program.

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