scholarly journals Segmental Zoster Paresis: A Literature Review

2021 ◽  
pp. 253-261
Author(s):  
Buwei Yu
Keyword(s):  
Clinical Trials ◽  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Case Reports ◽  
Motor Nerve ◽  
Clinical Manifestations ◽  
Diagnostic Methods ◽  
Sensory Nerves ◽  
Varicella Zoster Virus Infection ◽  
Varicella Zoster

Background: Herpes zoster is an acute infectious skin disease that is induced by the re-activation of the virus incubated in nerve ganglions following initial infection with varicella-zoster virus in childhood. Herpes zoster mainly affects sensory nerves, resulting in severe acute pain, which is also the most common reason for medical intervention in this patient group. The concurrent involvement of motor nerves could induce the symptoms of segmental zoster paresis, which is manifested by localized asymmetric myasthenia, whose range generally follows the distribution of myomere with skin rashes. Due to the low incidence and unspecific clinical manifestations, segmental zoster paresis has not been sufficiently recognized by clinicians, and can easily be misdiagnosed. Objective: To summarize the previous studies on segmental zoster paresis and analyze the pathogeneses, diagnosis, and treatment of this disease, as well as stress the challenges in current treatment, which could provide useful evidence for the clinical diagnosis and better the treatment of patients with segmental zoster paresis in the future. Study Design: We conducted a narrative review. Setting: Hospitals, neurology departments, pain departments, and private practices. Methods: We searched PubMed and Chinese CNKI libraries using the terms “herpes zoster,” “muscle paresis,” “segmental zoster paresis,” and “motor nerve.” Clinical trials, reviews, and case reports were collected and reviewed. Results: As a rare complication following varicella-zoster virus infection, segmental zoster paresis has not been sufficiently recognized by clinicians, and there are still no guidelines available to guide the clinical treatments. The exact mechanism of segmental zoster paresis is still unclear. Electromyographic and magnetic resonance imaging examinations could be used as auxiliary diagnostic methods for segmental zoster paresis. Early regular anti-viral therapy could substantially decrease the risk of herpes zoster related complications. Combined application of glucocorticoids and some other physical therapy may also be useful in certain patients. The general prognosis of segmental zoster paresis is relatively good, with 67% patients achieving complete or almost complete recovery of the muscle function. Limitations: More clinical trials are needed to clarify the exact mechanisms and best treating methods. Conclusion: As the symptom in most segmental zoster paresis patients is self-limited, and the patients’ prognosis is generally good, early diagnosis of the disease is especially important, due to the avoidance of unnecessary diagnostic procedures and incorrect treatments. Standard treatment guidelines regarding the functional rehabilitation are still needed for patients with refractory segmental zoster paresis. Key words: Herpes zoster, postherpetic neuralgia, segmental zoster paresis, muscle strength, motor nerve, spinal dorsal ganglion, zoster infection, muscle paresis

scholarly journals Herpes zoster recurrence within 1 month: A case report

2021 ◽  
Vol 19 ◽  
pp. 205873922110212
Author(s):  
Nan Zhao ◽  
Yulan Geng ◽  
Yexian Li ◽  
Lijuan Liu ◽  
Yanjia Li ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Case Report ◽  
Herpes Zoster ◽  
B Cells ◽  
Varicella Zoster Virus ◽  
Lower Limit ◽  
Skin Disease ◽  
Clinical Manifestations ◽  
Varicella Zoster ◽  
Humoral Immune

Herpes zoster (HZ), caused by the varicella-zoster virus, is an infectious skin disease that rarely recurs after initial presentation. The mechanism underlying HZ recurrence is currently under investigation. In this article, we report a case of HZ relapse within 1 month. Analysis of patient’s clinical manifestations, histopathological features, and flow cytometry results indicated that the absolute and percentage values of B cells were below the lower limit. We hypothesized that the patient had abnormal humoral immune function, which may be one reason leading to the HZ relapse within 1 month. The findings of this case will serve as useful reference for HZ recurrence for clinicians. This case was impactful and added to the literature on HZ recurrence.

High Incidence of Varicella Herpes Zoster with Use of Bortezomib in Chinese Patients.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 5114-5114
Author(s):  
Yin Tong ◽  
Jie Jing Qian ◽  
Ying Li ◽  
Hai Tao Meng ◽  
Jie Jin
Keyword(s):  
Multiple Myeloma ◽  
Herpes Zoster ◽  
Virus Infection ◽  
Varicella Zoster Virus ◽  
Cell Lymphoma ◽  
Acute Myeloblastic Leukemia ◽  
Chinese Patients ◽  
Varicella Zoster Virus Infection ◽  
Varicella Zoster ◽  
High Incidence

Abstract Bortezomib has been used for patients with refractory and relapsed multiple myeloma, non-Hodgkin lymphoma and leukemia in recent years. It has several complications. Here we report the complication of varicella herpes zoster after using bortezomib, which has higher incidence in Chinese patients. Ten patients were treated with bortezomib in our hematology centre. Among them, seven patients had refractory and relapsed multiple myeloma, two patients had refractory lymphoma (one of T cell lymphoma and one of mantle cell lymphoma) and one patient had refractory acute myeloblastic leukemia. All the patients received bortezomib (1.3 mg/m2) on days 1, 4, 8, and 11 of a 3-week cycle. Patients of multiple myeloma received dexamethasone simultaneously. The combination with liposomal doxorubicin was used on the patients of lymphoma. The patient of acute myeloblastic leukemia received bortezomib in combination with Amsacrine. After one cycle, 6 patients with multiple myeloma responded to treatment (four near complete remission, two partly remission). Two patients with lymphoma reached PR. The patient with leukemia had no response. A remarkable observation in our treatment was the high incidence of varicella herpes zoster. Six out of ten patients developed varicella herpes zoster. Among the six patients, two patients had previous infection of the zoster virus before. Most of the patients had the varicella herpes zoster infection after the complete of one cycle of bortezomib and were disappeared within one month by the use of antiviral treatment. The incidence of varicella hepers zoster after bortezomib was around 13% as reported. But the higher incidence of varicella herpes zoster were observed in our patients. Six of ten patients (60%) developed varicella zoster virus infection during treatment. We considered that the Chinese patients may be more liable to varicella zoster virus infection. And further observations should be made in the future. Prophylactic antiviral medication might be used in predisposed patients who receive bortezomib.

scholarly journals Acute Urinary Retention Following Primary VaricellaZoster Virus Infection

2021 ◽  
Vol 2 (2) ◽  
pp. 59-61
Author(s):  
Kamran Hassan Bhatti
Keyword(s):  
Herpes Zoster ◽  
Virus Infection ◽  
Varicella Zoster Virus ◽  
Urinary Retention ◽  
Acute Urinary Retention ◽  
Treatment Plan ◽  
Varicella Zoster Virus Infection ◽  
Lumbosacral Region ◽  
Varicella Zoster ◽  
Urological Symptoms

Background Acute urinary retention following primary varicella-zoster virus infection (chickenpox) is very rare. Case Presentation We present a case of 34 years old male patient presented with acute urinary retention following primary varicella-zoster virus infection (chickenpox), there was no lesion detected neither by MRI brain nor whole spinal cord imaging. There was a typical blistering rash over the face, trunk, back and upper limbs but sparing the perennial and perianal area. Conclusion Once herpes zoster is found in lumbar lumbosacral region be alert there is possibility of voiding dysfunction like acute retention of urine. The effective treatment plan includes antiviral therapy and urethral catheterization. Most of urological symptoms due to herpes zoster subsides in the very short duration with active guideline treatment. Keywords: Varicella-zoster virus infection; Blister-like rash; Acute urinary retention.

scholarly journals Prevention & Management of Herpes Zoster- an Update

2014 ◽  
Vol 41 (3) ◽  
pp. 53-56
Author(s):  
AKM Rejaul Haque ◽  
A Sultana ◽  
A Habib ◽  
ASM Zakaria
Keyword(s):  
Herpes Zoster ◽  
Virus Infection ◽  
Varicella Zoster Virus ◽  
Age Factors ◽  
Varicella Vaccine ◽  
Varicella Zoster Virus Infection ◽  
Post Herpetic Neuralgia ◽  
Varicella Zoster ◽  
Burning Pain ◽  
Chronic Corticosteroid

Herpes zoster (commonly referred to as "shingles") results .from reactivation of the varicella-zoster virus infection, or chickenpox. Were as varicella is generally a disease of childhood, herpes zoster becomes more common with increasing age Factors that decrease immune function, such as human immunodeficiency virus infection, chemotherapv, malignancies and chronic corticosteroid use, may also increase the risk of developing herpes zoster. Reactivation of latent varicella-zoster virus from dorsal root ganglia is responsible.for lhe classic dermatomal rash and pain that occur with herpes zoster. Burning pain typically precedes the rash by several days and can persist for several months after the rash resolves. With post herpetic neuralgia, a complication of herpes zoster, pain may persist well after resolution of the rash and can be highly debilitating. Although the diagnosis of the conditions is generally straightforward, treatment can be frustrating for the patient and physician. Approaches to management include treatment of the herpes zoster infection and associated pain, prevention of post herpetic neuralgia, and control of the neuropathic pain until the condition resolves. Herpes zoster is contagious to those who have not had varicella or have not received the varicella vaccine. The role of the varicella vaccine in preventing herpes zoster is uncertain, but is being studied. The management of herpes zoster is challenging because many patients develop troublesome complication. So, appropriate management o/'herpes zoster is very important to avoid complication. On the other hand prevention is better than cure. Immunization with varicella zoster virus vaccine may boost humoral and cell mediated and decrease the incidence of zoster in population. So effectiveness of a vaccination program need to be evaluated. immunity DOI: http://dx.doi.org/10.3329/bmj.v41i3.18961 Bangladesh Medical Journal 2012 Vol.41(3): 53-56

scholarly journals Varicella Zoster Antibodies after Herpes Zoster, Varicella and Multiple Sclerosis

1997 ◽  
Vol 24 (2) ◽  
pp. 137-139 ◽  
Author(s):  
R.T. Ross ◽  
L.E. Nicolle ◽  
M.R. Dawood ◽  
Mary Cheang ◽  
C. Feschuk
Keyword(s):  
Herpes Zoster ◽  
Virus Infection ◽  
Varicella Zoster Virus ◽  
Population Group ◽  
Population Based ◽  
Postal Code ◽  
Enzyme Linked Immunosorbent Assay ◽  
Varicella Zoster Virus Infection ◽  
Varicella Zoster ◽  
Physician Care

ABSTRACT:Background:We previously showed that Manitoba Hutterites seek physician care for varicella zoster virus infection significantly less than non-Hutterites. The current study was undertaken to measure varicella zoster virus seroprevalence for Hutterite and non-Hutterite controls.Methods:Blood was obtained from 315 Hutterites and 259 similar age and sex controls at the time of blood donations to The Canadian Red Cross Society. The controls were from the same or a contiguous postal code area and were collected at the same time as the Hutterite samples. The immune status of the specimens was determined by the ELISA method (enzyme linked immunosorbent assay).Results:Twenty-eight per cent of 315 Hutterites had no immunity and an additional 25% had only marginal immunity. Among the 259 controls, 10% had no immunity and an additional 10% had only marginal immunity (p < .0001).Conclusions:Manitoba Hutterites have significantly decreased seroprevalence to varicella zoster virus infection. This study of serum varicella zoster virus antibodies verifies a previous population based study that demonstrated the relative rarity of varicella and herpes zoster among a particular population group.

scholarly journals The Skin and the Eye - Herpes Zoster Ophthalmicus in a Healthy 18-month-old Toddler

Folia Medica ◽  
2018 ◽  
Vol 60 (1) ◽  
pp. 170-174 ◽  
Author(s):  
Radka T. Komitova ◽  
Oliana B. Boykinova ◽  
Nina S. Stoyanova
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Late Pregnancy ◽  
Varicella Zoster Virus Infection ◽  
First Year ◽  
Healthy Children ◽  
Herpes Zoster Ophthalmicus ◽  
Varicella Zoster ◽  
First Year Of Life ◽  
Ophthalmic Branch

Abstract Herpes zoster, caused by reactivation of varicella-zoster virus, is uncommon in infancy. Even more uncommon is herpes zoster ophthalmicus, defined as herpes zoster of the ophthalmic branch of the fifth cranial nerve. Among healthy children, primary varicella-zoster virus infection during gestation as a result of maternal varicella or the first year of life is the major risk factor for development of herpes zoster in a relatively young age. Here we present an unusual case of herpes zoster ophthalmicus with dissemination in an immunocompetent toddler with favorable outcome. The child’s mother contracted chickenpox in late pregnancy and her son was very likely infected with varicella-zoster virus in utero. During a two-year follow-up the child vision was normal and there was no evidence of post herpetic neuralgia.

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