scholarly journals BURST(able): A Retrospective, Multicenter Study Examining the Impact of Spinal Cord Stimulation with Burst on Pain and Opioid Consumption in the Setting of Salvage Treatment and “Upgrade”

2020 ◽  
Vol 6;23 (11;6) ◽  
pp. E643-E658
Keyword(s):  
Spinal Cord ◽  
Multicenter Study ◽  
Spinal Cord Stimulation ◽  
Salvage Treatment ◽  
Opioid Consumption ◽  
The Impact ◽  
Retrospective Multicenter Study

Retrospective analysis on the effect of spinal cord stimulation on opioid consumption

2020 ◽  
Author(s):  
Awinita Barpujari ◽  
Michael A Erdek
Keyword(s):  
Spinal Cord ◽  
Chronic Pain ◽  
Retrospective Analysis ◽  
Spinal Cord Stimulation ◽  
Alternative Therapy ◽  
Opioid Consumption ◽  
Opioid Use ◽  
Number Of Patients ◽  
Chronic Pain Conditions ◽  
Post Trial

Aim: Spinal cord stimulation (SCS) is used to clinically manage and/or treat several chronic pain etiologies. A limited amount is known about the influence on patients' use of opioid pain medication. This retrospective analysis evaluated SCS effect on opioid consumption in patients presenting with chronic pain conditions. Materials & methods: Sixty-seven patients underwent a temporary trial device, permanent implant or both. Patients were divided for assessment based on the nature of their procedure(s). Primary outcome was change in morphine equivalent dose (MED), ascertained from preoperative and postoperative medication reports. Results: Postoperative MED was significantly lower in patients who received some form of neuromodulation therapy. Pretrial patients reported an average MED of 41.01 ± 10.23 mg per day while post-trial patients reported an average of 13.30 ± 5.34 mg per day (p < 0.001). Pre-implant patients reported an average MED of 39.14 ± 13.52 mg per day while post-implant patients reported an average MED of 20.23 ± 9.01 mg per day (p < 0.001). There were no significant differences between pre-trial and pre-implant MED, nor between post-trial and post-implant MED. Of the 42 study subjects who reported some amount of pre-intervention opioid use, 78.57% indicated a lower MED (n = 33; p < 0.001), 16.67% indicated no change (n = 7) and 4.76% (n = 2) indicated a higher MED, following intervention. Moreover, SCS therapy resulted in a 26.83% reduction (p < 0.001) in the number of patients with MED >50 mg per day. Conclusion: Spinal cord stimulation may reduce opioid use when implemented appropriately. Neuromodulation may represent alternative therapy for alleviating chronic pain which may avoid a number of deleterious side effects commonly associated with opioid consumption.

scholarly journals Pain relief and opioid usage in upper limb and neck pain patients after 10-kHz spinal cord stimulation treatment: subanalysis of USA studies

2020 ◽  
Author(s):  
Kasra Amirdelfan ◽  
Ricardo Vallejo ◽  
Ramsin Benyamin ◽  
Steven Rosen ◽  
Peter Kosek ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Pain Relief ◽  
Neck Pain ◽  
Spinal Cord Stimulation ◽  
Opioid Consumption ◽  
Upper Limbs ◽  
Opioid Use ◽  
Scale Scores ◽  
Post Hoc ◽  
Pain Patients

Aim: It is argued that chronic pain patients who reduce/eliminate their opioids may have compromised pain relief. This study therefore aimed to analyze if reduced opioid consumption associated with 10-kHz spinal cord stimulation adversely affected pain relief. Methods: Post hoc analysis was performed on data from two prospective studies in subjects with upper limbs and neck pain conducted in USA. Results & conclusion: A 10-kHz spinal cord stimulation treatment was associated with reduction in mean visual analog scale scores for upper limbs and neck pain and mean daily opioid consumption. Pain scores decreased in subjects who decreased opioid use and in those who maintained/increased use. Opioid reduction and pain relief was also achieved in subjects taking >90 mg morphine equivalents of opioids at baseline.

A Prospective, Open-Label, Multicenter Study to Assess the Efficacy of Spinal Cord Stimulation and Identify Patients Who Would Benefit

2012 ◽  
Vol 15 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Kazuhide Moriyama ◽  
Kazushige Murakawa ◽  
Takeshi Uno ◽  
Kiyoshige Oseto ◽  
Minoru Kawanishi ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Multicenter Study ◽  
Spinal Cord Stimulation ◽  
Open Label

The impact of obesity on the effectiveness of spinal cord stimulation in chronic spine-related pain patients

2019 ◽  
Vol 19 (3) ◽  
pp. 476-486 ◽  
Author(s):  
Nagy Mekhail ◽  
Diana Mehanny ◽  
Sherif Armanyous ◽  
Youssef Saweris ◽  
Shrif Costandi
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Stimulation ◽  
The Impact ◽  
Pain Patients

scholarly journals Effects of Relaxed Lockdown on Pediatric ER Visits during SARS-CoV-2 Pandemic in Italy

2021 ◽  
Vol 18 (18) ◽  
pp. 9547
Author(s):  
Luigi Matera ◽  
Raffaella Nenna ◽  
Francesca Ardenti Morini ◽  
Giuseppe Banderali ◽  
Mauro Calvani ◽  
...  
Keyword(s):  
Emergency Room ◽  
Multicenter Study ◽  
Preventive Measures ◽  
Pediatric Emergency ◽  
Communicable Diseases ◽  
Social Activities ◽  
Triage Category ◽  
The Impact ◽  
Retrospective Multicenter Study

Previously, we demonstrated an 81% reduction in pediatric Emergency Room (ER) visits in Italy during the strict lockdown due to the SARS-CoV-2 pandemic. Since May 2020, lockdown measures were relaxed until 6 November 2020, when a strict lockdown was patchily reintroduced. Our aim was to evaluate the impact of the relaxed lockdown on pediatric ER visits in Italy. We performed a retrospective multicenter study involving 14 Italian pediatric ERs. We compared total ER visits from 24 September 2020 to 6 November 2020 with those during the corresponding timeframe in 2019. We evaluated 17 ER specific diagnoses grouped in air communicable and non-air communicable diseases. We recognized four different triage categories: white, green, yellow and red. In 2020 total ER visits were reduced by 51% compared to 2019 (16,088 vs. 32,568, respectively). The decrease in air communicable diseases was significantly higher if compared to non-air communicable diseases (−64% vs. −42%, respectively). ER visits in each triage category decreased in 2020 compared to 2019, but in percentage, white and red codes remained stable, while yellow codes slightly increased and green codes slightly decreased. Our results suggest that preventive measures drastically reduced the circulation of air communicable diseases even during the reopening of social activities but to a lesser extent with regard to the strict lockdown period (March–May 2020).

scholarly journals Spinal Cord Stimulation for Complex Regional Pain Syndrome: A Case Study of a Pregnant Female

2016 ◽  
Vol 3;19 (3;3) ◽  
pp. E487-E493
Author(s):  
Shaik Ahmed
Keyword(s):  
Spinal Cord ◽  
Complex Regional Pain Syndrome ◽  
Spinal Cord Stimulation ◽  
Treatment Options ◽  
Pain Syndrome ◽  
Conclusive Evidence ◽  
Treatment Modalities ◽  
Child Bearing ◽  
The Impact

Background: Spinal cord stimulation (SCS) is a form of neuromodulation, used to treat chronic neuropathic pain refractory to conventional medical management. Spinal cord stimulators are treatment options when intractable chronic pain has not responded to more conventional treatment modalities. Currently, the use of SCS is contraindicated in pregnancy. Nevertheless, many SCS/ neuromodulation recipients are women of child bearing age who may become pregnant. There are no published reports that focus on the possible side effects of SCS or neuromodulation therapy on human fertility, fetal development, pregnancy, delivery, or lactation. Objectives: The purpose of this current report is to present a case study on the use of SCS/ neuromodulation during pregnancy. Study Design: Presentation of the case of a 24 year old female who became pregnant after receiving an SCS implantation for pain control secondary to complex regional pain syndrome (CRPS). The SCS was in use at the time of conception but deactivated when patient became aware of her pregnancy and intermittently reactivated for five minute intervals throughout the entire pregnancy. Results: Currently very little documented evidence is available regarding the safety of using a SCS/ neuromodulator during pregnancy; therefore its use during pregnancy is contraindicated. Available literature suggests that, women who have chosen to keep the SCS/neuromodulator activated during pregnancy have delivered healthy babies without any life threatening complications. Limitations: Case presentations do not provide conclusive evidence of treatment effectiveness. This data is only preliminary and future studies should be used to assess outcomes and measures to provide quantification of the SCS implantation during pregnancy. Conclusions: Women of child bearing age who are recipients of SCS/neuromodulation implantation should be informed of the limited knowledge available regarding the impact of SCS/ neuromodulation use during pregnancy. For current recipients, decisions about ongoing use during pregnancy should be an individual decision based on the potential risks and benefits. Key words: Pregnancy and complex regional pain syndrome, pregnancy and reflex sympathetic dystrophy, pregnancy and spinal cord stimulators, pregnancy and electromagnetic fields, and pregnancy and neuromodulator.

Prospective, Multicenter Study of Spinal Cord Stimulation for Relief of Chronic Back and Extremity Pain

Spine ◽  
1996 ◽  
Vol 21 (23) ◽  
pp. 2786-2794 ◽  
Author(s):  
Kim J. Burchiel ◽  
Valerie C. Anderson ◽  
Frederick D. Brown ◽  
Richard G. Fessler ◽  
William A. Friedman ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Multicenter Study ◽  
Spinal Cord Stimulation ◽  
Prospective Multicenter Study

scholarly journals 10‐kHz Spinal Cord Stimulation for Chronic Postsurgical Pain: Results From a 12‐Month Prospective, Multicenter Study

Pain Practice ◽  
2020 ◽  
Vol 20 (8) ◽  
pp. 908-918 ◽  
Author(s):  
Mayank Gupta ◽  
James Scowcroft ◽  
Daniel Kloster ◽  
Maged Guirguis ◽  
Jonathan Carlson ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Multicenter Study ◽  
Spinal Cord Stimulation ◽  
Prospective Multicenter Study ◽  
Postsurgical Pain ◽  
Chronic Postsurgical Pain
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