scholarly journals Critics on Policy of Soy-Based Infant Formula in Indonesia: Compared to Australian and New Zealand Food Standards

2019 ◽  
Vol 3 (3) ◽  
pp. 152
Author(s):  
Agnescia Clarissa Sera
Keyword(s):  
New Zealand ◽  
Infant Formula ◽  
Aluminum Content ◽  
Epidemiological Studies ◽  
World Health ◽  
Infant Food ◽  
Infant Formulas ◽  
Food Standards ◽  
World Health Organiza

Background: World Health Organiza on (WHO) recommends breast milk as sole and the most complete infant food during the first 6 months. However, in certain circumstances, when breas eeding is not possible, not de- sired or not advised, infant formulas like those are made of soy can be given to newborns. However, the safety of long-term use soy-based formula has been argued due to the possible adverse effects of phytoestrogen, phytates and aluminum in human body as well as the consequences of agrochemicals residue. Therefore, those problems should be taken into account while developing, reviewing or amending policy of infant formulas. This ar cle re- views the adequacy of soy-based infant formula policy in Indonesia to an cipate issues in SIF consump on. Methods: Australian and New Zealand Food Standards Code was used to compared to the decree of Indonesian NADFC. The results were described narra vely and analyzed from the perspec ve of the author. Results: Accordingly, only small aspects of SIF are regulated in Indonesian policy. The use of SPI for SIF in In- donesia is not a compulsory though scien fically another source may trigger diarrhea in newborn baby. No clause related to aluminum content, zinc to copper ra o, isoflavone level, GM soy and pes cide residue found in In- donesian policy. Conclusion: Apparently, very limited provision regarding SIF has been covered by Indonesian policy. The regu- la on of SIF marketed and manufactured in Indonesia should be more specific and developed based on recent clinical and epidemiological studies. On the other hand, Indonesia needs a comprehensive system where society may par cipate in reviewing the laws.

scholarly journals Evaluation of Heavy Metals Profile in Different Brands of Infant Food Nutrition

2019 ◽  
pp. 1-9
Author(s):  
Ogochukwu Augustina Onuorah ◽  
Rufus Sha'ato ◽  
Fina Okeke ◽  
Adekola Omololu Atanda ◽  
Agbele Idowu Elijah ◽  
...  
Keyword(s):  
Trace Metals ◽  
Infant Formula ◽  
Daily Intake ◽  
World Health ◽  
Infant Food ◽  
Formula Milk ◽  
Infant Formulae ◽  
Infant Formula Milk ◽  
Significant Difference ◽  
Toxic Trace Metals

The concentrations of five essential metals in six selected (NAN, Cowbell, MY BOY, CERELAC, FRISO GOLD and NUTREND) infant formulae sold in Makurdi metropolis, were determined using Atomic Absorption Spectrophotometer. Data collected were subjected to Analysis of Variance using SPSS 24 statistical software package. Significant differences in means were separated using Duncan Multiple Range Test. There was significant difference in the levels of the trace metals in the different brands of infant formula milk. The results of the toxic trace metals show that Cr has the highest concentration of 6.175 ±0.001 mg/kg (Cowbell), when compared to other toxic trace metals analyzed. Milk based infant formula showed copper concentration ranged from 2.55±0.001– 6.357±0.001mg/kg, which was higher than the provisional tolerable daily intake of copper that is 3 mg/kg. Chromium, Copper, Manganese and lead were detected in the six brands of infant formula milk but they were below the limits set by World Health Organization (WHO). However, the intake levels of Cd in this study from these concentrations were below the WHO limits. These results validate and in some cases counter earlier reports on the composition of infant formula found in our local markets. Therefore, the concentrations of the studied elements were within the safe limits recommended by National Industrial Standard and the Institute of Medicine for foods but higher concentrations of trace metals in some brands of infant formulae above the recommended limit pose a risk of bioaccumulation.

scholarly journals Effects of infant formula composition on long-term metabolic health

2018 ◽  
Vol 9 (6) ◽  
pp. 573-589 ◽  
Author(s):  
M. Lemaire ◽  
I. Le Huërou-Luron ◽  
S. Blat
Keyword(s):  
Gut Microbiota ◽  
Infant Formula ◽  
Gold Standard ◽  
Metabolic Health ◽  
Infant Formulas ◽  
Lipid Matrix ◽  
Early Nutrition ◽  
Formula Composition ◽  
Host Metabolism

Early nutrition may have long-lasting metabolic impacts in adulthood. Even though breast milk is the gold standard, most infants are at least partly formula-fed. Despite obvious improvements, infant formulas remain perfectible to reduce the gap between breastfed and formula-fed infants. Improvements such as reducing the protein content, modulating the lipid matrix and adding prebiotics, probiotics and synbiotics, are discussed regarding metabolic health. Numerous questions remain to be answered on how impacting the infant formula composition may modulate the host metabolism and exert long-term benefits. Interactions between early nutrition (composition of human milk and infant formula) and the gut microbiota profile, as well as mechanisms connecting gut microbiota to metabolic health, are highlighted. Gut microbiota stands as a key actor in the nutritional programming but additional well-designed longitudinal human studies are needed.

scholarly journals Dietary Protein, Kidney Function and Mortality: Review of the Evidence from Epidemiological Studies

Nutrients ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 196 ◽  
Author(s):  
Giancarlo Bilancio ◽  
Pierpaolo Cavallo ◽  
Carolina Ciacci ◽  
Massimo Cirillo
Keyword(s):  
Kidney Function ◽  
Protein Intake ◽  
Substantial Reduction ◽  
Epidemiological Studies ◽  
World Health ◽  
Normal Kidney ◽  
Ideal Weight ◽  
Normal Kidney Function ◽  
Kidney Function Decline

The World Health Organization recommends a minimum requirement of 0.8 g/day protein/kg ideal weight. Low protein diets are used against kidney failure progression. Efficacy and safety of these diets are uncertain. This paper reviews epidemiological studies about associations of protein intake with kidney function decline and mortality. Three studies investigated these associations; two reported data on mortality. Protein intake averaged >60 g/day and 1.2 g/day/kg ideal weight. An association of baseline protein intake with long-term kidney function decline was absent in the general population and/or persons with normal kidney function but was significantly positive in persons with below-normal kidney function. Independent of kidney function and other confounders, a J-curve relationship was found between baseline protein intake and mortality due to ≈35% mortality excess for non-cardiovascular disease in the lowest quintile of protein intake, a quintile where protein intake averaged <0.8 g/day/kg ideal weight. Altogether, epidemiological evidence suggests that, in patients with reduced kidney function, protein intakes of ≈0.8 g/d/kg ideal weight could limit kidney function decline without adding non-renal risks. Long-term lower protein intake could increase mortality. In most patients, an intake of ≈0.8 g/day/kg would represent a substantial reduction of habitual intake considering that average intake is largely higher.

Developmental Effects and Health Aspects of Soy Protein Isolate, Casein, and Whey in Male and Female Rats

2001 ◽  
Vol 20 (3) ◽  
pp. 165-174 ◽  
Author(s):  
Thomas M. Badger ◽  
Martin J. J. Ronis ◽  
Reza Hakkak
Keyword(s):  
Infant Formula ◽  
Soy Protein ◽  
Soy Protein Isolate ◽  
Protein Isolate ◽  
Female Rats ◽  
Male Rats ◽  
Infant Formulas ◽  
Developmental Effects ◽  
17Β Estradiol

Dietary factors other than the traditional nutrients are found in the so-called functional foods. They are becoming increasingly recognized as potentially important for maintaining good health. Soybeans are rich in such factors thought to help prevent certain chronic diseases. Soy protein isolate (SPI) is one of the three major proteins used in infant formulas sold in the United States, with casein (CAS) and whey (WPH) proteins being the others. We have been studying the health effects of these proteins. Safety concerns have developed over the consumption of soy-based infant formula, partly because of the high circulating levels of the total isoflavones (phytoestrogens) during “critical periods of infant development.” There is a paucity of data on developmental, physiological, neurophysiological, behavioral, metabolic, or molecular effects of soy phytochemicals in humans, especially during pregnancy and infancy. We have studied the effects of CAS, SPI, and WPH in short-term, long-term, and multigenerational studies in rats. Aside from minor differences in body weight gain profiles, CAS-, SPI-or WPH-fed rats did not differ in development, organ weights, in vitro hepatic metabolism of testosterone (T), or reproductive performance. However, some endocrine-related functions differed between rats fed these proteins. We found that SPI accelerated puberty in female rats ( p <.05) and WPH delayed puberty in males and females, as compared with CAS ( p <.05). Gender differences were also found in gonadectomy-induced steroid responses. Male rats had normal serum T levels, but female rats fed SPI had reduced serum 17β-estradiol concentrations and a blunted 17β-estradiol response to ovariectomy, as compared to rats fed CAS or WHP ( p <.05). Female rats fed SPI or WHP or treated with genistein had reduced incidence of chemically induced mammary cancers ( p <.05) compared to CAS controls, with WHP reducing tumor incidence by as much as 50%, findings that replicate previous results from our laboratory. Together, these results suggest gender-specific differences in development and certain endocrine responses among rats fed diets composed of a single protein source such as those used in infant formulas. Whether similar developmental effects occur in human infants is unknown, but unlikely because (1) most infants do not consume such diets throughout life as these rats did, and (2) no such effects have been reported in millions of American infants fed infant formula containing these proteins. The long-term health consequence implications of early diet exposure to SPI and WPH, such as reduced breast cancer incidence, are likely to be very positive.

scholarly journals Quantification of health effects of exposure to air pollution (PM10) in Tabriz, Iran

2016 ◽  
Vol 18 (4) ◽  
pp. 708-720 ◽  
Keyword(s):  
Respiratory Diseases ◽  
Epidemiological Studies ◽  
World Health ◽  
Health Impacts ◽  
Respiratory Mortality ◽  
Increased Risk ◽  
Health Organization ◽  
Risk Of Cancer ◽  
The City

<div> <p>Epidemiological studies show that long-term exposure to PM is associated with an increased risk of cancer or cardiovascular and respiratory diseases. The main objective of the present study was the assessment of health outcomes related to PM<sub>10</sub> (particulate matter (PM) of aerodynamic diameter &le; 10 &micro;m) exposure in Tabriz, Iran. Related health impacts (relative risk and baselineincidence) due to exposure to PM<sub>10 </sub>in the city of Tabriz were assessed by using the well-established AirQ2.2.3 model by the World Health Organization European Center for Environment Health. We estimated that out of 15,651 total deaths in the city, 7679 and 1020 people died due to cardiovascular and respiratory related deaths respectively. Among the 19,467 people admitted to hospital due to respiratory disease, 1114 diseases could be attributed to PM<sub>10</sub>. According to this model, cases of natural mortality, cardiovascular deaths and respiratory mortality caused by PM<sub>10 </sub>were about 832, 439, and 85, respectively.</p> </div> <p>&nbsp;</p>

scholarly journals Uncertainty around the Long-Term Implications of COVID-19

Pathogens ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1267
Author(s):  
Marc Desforges ◽  
Deepti Gurdasani ◽  
Adam Hamdy ◽  
Anthony J. Leonardi
Keyword(s):  
New Zealand ◽  
Acute Infection ◽  
Viral Persistence ◽  
Immune Dysregulation ◽  
Mitigation Strategies ◽  
World Health ◽  
Infection Rates ◽  
The World ◽  
Health Organization

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 231 million people globally, with more than 4.7 million deaths recorded by the World Health Organization as of 26 September 2021. In response to the pandemic, some countries (New Zealand, Vietnam, Taiwan, South Korea and others) have pursued suppression strategies, so-called Zero COVID policies, to drive and maintain infection rates as close to zero as possible and respond aggressively to new cases. In comparison, European countries and North America have adopted mitigation strategies (of varying intensity and effectiveness) that aim primarily to prevent health systems from being overwhelmed. With recent advances in our understanding of SARS-CoV-2 and its biology, and the increasing recognition there is more to COVID-19 beyond the acute infection, we offer a perspective on some of the long-term risks of mutational escape, viral persistence, reinfection, immune dysregulation and neurological and multi-system complications (Long COVID).

Plant mortality and seedling recruitment responses to flupropanate in grassland populations of Nassella trichotoma

2017 ◽  
Vol 70 ◽  
pp. 160-164 ◽  
Author(s):  
G.W. Bourdôt ◽  
S. Jackman ◽  
D.J. Saville
Keyword(s):  
New Zealand ◽  
Dose Response ◽  
Sodium Salt ◽  
Seedling Recruitment ◽  
Residual Activity ◽  
Application Rate ◽  
Plant Mortality ◽  
Complete Control ◽  
Bio Synthesis

Flupropanate (sodium 2,2,3,3 tetrafluoropropanate), a slow-acting lipid bio- synthesis-inhibiting herbicide, was recently registered in New Zealand as Taskforce (745 g/L flupropanate as the sodium salt) for the selective and long-term control of Nassella trichotoma (nassella tussock) in pastures. In five dose-response experiments in permanent hill pastures in Canterbury, conducted between 2012 and 2016, we measured the efficacy of the herbicide against established plants of N. trichotoma and its residual activity against recruiting seedlings. Mortality, as an average across the five sites, was 93% 1.5 years after applying 1.49 kg flupropanate/ha (the label-recommended rate), and 100% at 2.98 kg/ha. This indicates that an application rate higher than the label rate will be necessary for complete control of a N. trichotoma infestation. The presence of 1,000 and 6,250 visible seedlings of N. trichotoma/ha in the autumn 3.2 and 2.1 years after applying 1.49 kg flupropanate/ha (at a Greta Valley and Scargill site respectively) indicates that the herbicide’s soil residues had decayed within 12 months to a concentration lower than necessary to kill the germinating seedlings of N. trichotoma.

STEVIA PLANT - ALTERNATIVE SWEETNER IN FOOD TECHNOLOGY

2018 ◽  
Vol 28 (4) ◽  
pp. 1213-1217
Author(s):  
Jovana Džoljić ◽  
Ljiljana Đorđević
Keyword(s):  
Food Additives ◽  
Functional Class ◽  
World Health ◽  
Food Technology ◽  
Food Standards ◽  
Safety Studies ◽  
Negative Side Effects ◽  
Health Organization ◽  
Almost All ◽  
Agricultural Organization

Food and Agricultural Organization as a “sweeteners” consider products used for sweetening derived from sugar crops, cereals, fruits or milk, or that are produced by insects. Sweeteners, as an additive, have important role for technological functions of food, especially in providing texture, bulk and color, and also as preservative agents. Regardless the numerous sweeteners, alternative sweeteners to sucrose are in main focus for implementation in food industry. Nowadays Food and Agricultural Organization and World Health Organization Food standards, Codex Alimentarius Commission (2018) accepted list of 27 food additives that have the functional class “sweetener”. Nowadays, alternative sweeteners and their application in food technology are in main focus of scientist. Stevia plant stands for one of the most important natural intense sweetener, since stevia glycosides are almost 400 times sweeter than sucrose. Extracts of stevia represents a powerful tool for reducing sugars in food and beverages, which can be acceptable substitutes to full sugar versions of this products. Regarding the data of Euromonitor international, new food products containing stevia grew 10% from 2016 to 2017. The biggest increment in stevia use was noticed in categories of snacks, juice drinks, dairy, carbonated soft drinks and confectionery. Barriocanal et al. (2008) highlighted that safety studies reported no negative side effects of stevia use. Can be expected that in recent future use of S. rebaudiana as sweetener would be extended to almost all the world’s countries, regarding all discovered beneficial health effects.

Enterococci in the New Zealand environment: implications for water quality monitoring

1997 ◽  
Vol 35 (11-12) ◽  
pp. 325-331 ◽  
Author(s):  
S. A. Anderson ◽  
S. J. Turner ◽  
G. D. Lewis
Keyword(s):  
Water Quality ◽  
New Zealand ◽  
Water Quality Monitoring ◽  
Epidemiological Studies ◽  
High Ratio ◽  
Quality Data ◽  
Considerable Proportion ◽  
Multiple Sources ◽  
Water Quality Data ◽  
Bathing Water Quality

Faecal enterococci ecology outside the host is of great relevance when using these organisms as indicators of water quality. As a complement to New Zealand epidemiological studies of bathing water quality and health risk, a study of the environmental occurrence of these organisms has been undertaken. Specific concerns over the use of enterococci derive from the unique situation in New Zealand which has few chlorinated sewage effluents, a high ratio of grazing animals to humans, and significant inputs of animal processing effluents into the environment. Human and animal faecal wastes are the main sources, with 106–107cfu/100ml found in human sewage. Analysis of domestic and feral animal faeces found enterococci in the range of 101–106cfu/g with considerable variation between species. The latter observations support the notion that a considerable proportion of the load in urban/rural catchments and waterways (typically 102–103 enterococci cfu/100ml) is derived from non-human sources. Previous studies of enterococci quiescence in marine/fresh waters indicate that they enter a non-growth phase, exposure to sunlight markedly reducing culturability on selective and non-selective media. Enterococci were also found to survive/multiply within specific non-faecal environments. Enterococci on degrading drift seaweed at recreational beaches exceeded seawater levels by 2–4 orders of magnitude, suggesting that expansion had occurred in this permissive environment with resultant potential to contaminate adjacent sand and water. These studies suggest that multiple sources, environmental persistence, and environmental expansion of enterococci within selected niches add considerable complexity to the interpretation of water quality data.

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