scholarly journals Gambaran kelainan katup jantung pada pasien infark miokard di RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari 2015-31 Desember 2015

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Mawarni I.S. Tumbel ◽  
Agnes L. Panda ◽  
Janry Pangemanan
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Retrospective Study ◽  
Heart Valve ◽  
St Elevation Myocardial Infarction ◽  
Papillary Muscles ◽  
Age Group ◽  
Cross Sectional ◽  
St Elevation ◽  
Cross Sectional Design

Abstract: Myocardial infarction is divided into STEMI (ST elevation myocardial infarction) and NSTEMI (Non ST elevation myocardial Infarction). According to location, infarction consists of inferior, lateral, and aortal. Inferior infarction often causes mitral valve and aortal abnormality due to papillary muscles rupture. This study was aimed to obtain the description of heart valve abnormality in myocardial infarction patients at Prof. Dr. R. D Kandou Hospital Manado from January 2015 to December 2015. This was a retrospective study with a cross sectional design. The results showed that there were 20 cases (90.9%) of NSTEMI and 2 cases (9.1%) of STEMI. The most location of infarction was inferior accounted for 10 cases (45.5%). The most heart valve abnormalities were combination abnormality accounted for 16 cases (72.7%); most were mild MR (5 cases; 55.6%), mild PR (5 cases; 55.6%), and mild TR (3 cases; 33.3%) in NSTEMI cases dominated by male cases (54.5%) and age group 56-66 years (40.9%), and combination of 4 major risk factors (59.1%).Keywords: description, heart valve abnormality, myocardial infarction Abstrak: Infark miokard terbagi menjadi STEMI (ST elevation myocardial infarction) dan NSTEMI (Non ST elevation myocardial infarction). Infark berdasarkan lokasi terdiri atas inferior, lateral, anterior dan aorta. Infark inferior sering menyebabkan kelainan katup mitral dan aorta akibat ruptur muskulus papilaris. Penelitian ini bertujuan untuk mengetahui gambaran kelainan katup jantung pada pasien infark miokard di RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari 2015 - 31 Desember 2015. Jenis penelitian ialah retrospektif dengan desain potong lintang. Hasil penelitian mendapatkan 20 kasus (90,9%) NSTEMI dan 2 kasus (9,1%) STEMI. Lokasi infark terbanyak yaitu inferior sebanyak 10 kasus (45,5%), didapati kelainan katup terbanyak yaitu kombinasi sebanyak 16 kasus (72,7%), dengan derajat terbanyak yaitu MR mild 5 kasus (55,6%), PR mild 5 kasus (55,6%) dan TR mild sebanyak 3 kasus (33,3%) pada pasien NSTEMI, yang didominasi oleh pasien laki-laki (54,5%), usia 56 – 66 tahun (40,9%), yang memiliki 4 faktor resiko mayor (59,1%). Kata kunci: gambaran, kelainan katup, infark miokard.

scholarly journals Pattern of Dyslipidemia in different type of Myocardial Infarction

2017 ◽  
Vol 5 (2) ◽  
pp. 106-109
Author(s):  
Md Zahid Alam ◽  
Aparna Rahman ◽  
Shabnam Jahan Hoque ◽  
SM Rezaul Irfan ◽  
Md Babul Miah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Prognostic Significance ◽  
Density Lipoprotein ◽  
St Elevation Myocardial Infarction ◽  
Coronary Risk Factors ◽  
Cross Sectional ◽  
Coronary Syndrome ◽  
Lipid Status ◽  
St Elevation

Background: Dyslipidemia is one of the main risk factors with prognostic significance in relation to coronary heart disease. Aggressive treatment has been recommended in acute coronary syndrome (ACS). We examined pattern of dyslipidemia in ST Elevation myocardial infarction (STEMI) and Non- ST elevation myocardial infarction (NSTEMI). We also compare the lipid status in between two types of myocardial infarction (MI).Methods: This cross sectional observational study was carried out enrolling 100 subjects with ST elevation and Non ST elevation Myocardial Infarction, in the Department of Cardiology, BIRDEM General Hospital, Shahbag, Dhaka, over a period of six months from January 2012 to June 2012. Fasting lipid profile was done in next morning of admission in both type of MI.Results: Mean age and gender difference was significant between STEMI and NSTEMI. Mean Cholesterol (chol), Triglyceride (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL) were not statistically significant between male and female groups. All mean cholesterol, TG, HDL, LDL were significantly high in older age group. The Mean cholesterol (220.7±28.1Vs208.4±20.9), triglyceride (182.8±34.4 Vs 147.4±28.9), HDL (35.14±5.7 Vs 41.65±3.8) and LDL (160.7±26.2 Vs148.3±16.8)were also statistically significant between STEMI and NSTEMI groups (p<0.05).Conclusion: Dyslipidemia is the dominating coronary risk factors. It could be concluded that significant differences are observed between two types of MI. Lipid status is relatively more uncontrolled in ST elevated MI and must be managed with all possible therapeutic modules to minimize further complications.Bangladesh Crit Care J September 2017; 5(2): 106-109

scholarly journals GAMBARAN PASIEN INFARK MIOKARD DENGAN ELEVASI ST (STEMI) YANG DIRAWAT DI BLU RSUP PROF. DR. R. D. KANDOU MANADO PERIODE JANUARI 2010 SAMPAI DESEMBER 2010

e-CliniC ◽  
2013 ◽  
Vol 1 (3) ◽  
Author(s):  
Edward August Wagyu
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Developing Countries ◽  
Risk Factor ◽  
Medical Records ◽  
Descriptive Study ◽  
Skin Tumor ◽  
St Elevation Myocardial Infarction ◽  
Age Group ◽  
St Elevation

Abstract :Introduction : ST Elevation Myocardial Infarction disease is the leading cause of death in some advance and developing countries. This disease caused by several risk factor, including unhealthy life style, have diabetic history before, uncontrol hypertension, ages, genders and stress.Objective: This study aims to determine how the image of patients with ST elevation myocardial infarction (STEMI) who were treated in the department of Prof.. DR. R.D. Kandou Manado for 1 year (1st January 2010 - 31st December 2010). A descriptive study of benign skin tumor of the medical records of new patients based on gender, age, location of the occurrence of myocardial infarction, myocardial infarction risk factors, onset of an attack, myocardial infarction complications occurring levels and TIMI risk stratification based on TIMI Risk Score.Results: There were 83 patients of ST Elevation Myocardial Infarction in this hospital. Highest age group is 60-69 years. This disease was almost found in men patients than women. Most risk factor was found in this study is uncontrolled hypertension.Conclusion: ST Elevation Myocardial Infarction is the most dangerous diseases in world that found in Heart and Cardiovascular department Dr Prof Dr. R. D. Kandou Manado. Highest age group is 60-69 years. ST Elevation Myocardial Infarction was more common in men. Most risk factor for this disease is uncontrol hypertension.Keyword: ST Elevation Myocardial Infarction disease, HeartAbstrak :Pendahuluan : ST Elevation Myocardial Infarction penyakit adalah penyebab utama kematian di beberapa muka dan negara-negara berkembang . Penyakit ini disebabkan oleh beberapa faktor risiko , termasuk gaya hidup yang tidak sehat , memiliki sejarah diabetes sebelumnya , hipertensi terkendali , usia , jenis kelamin dan stres Tujuan: Penelitian ini bertujuan untuk mengetahui bagaimana gambaran pasien dengan ST elevasi miokard infark ( STEMI ) yang dirawat di departemen Prof . DR . RD Kandou Manado selama 1 tahun ( 1 Januari 2010 - 31 Desember 2010) .Sebuah penelitian deskritif dari rekam medis pasien baru berdasarkan jenis kelamin, usia , lokasi terjadinya infark miokard , faktor risiko infark miokard , timbulnya serangan , komplikasi infark miokard terjadi tingkat dan TIMI stratifikasi risiko berdasarkan TIMI Skor Risiko.Hasil: Ada 83 pasien dari ST Elevation Myocardial Infarction di rumah sakit ini . Kelompok umur tertinggi adalah 60-69 tahun . Penyakit ini hampir ditemukan pada pria daripada wanita pasien . Kebanyakan faktor risiko ditemukan dalam penelitian ini adalah hipertensi yang tidak terkontrol .Kesimpulan : ST Elevation Myocardial Infarction adalah penyakit yang paling berbahaya di dunia yang ditemukan di Jantung dan Kardiovaskular departemen Dr Prof Dr RD Kandou Manado . Kelompok umur tertinggi adalah 60-69 tahun . ST Elevation Myocardial Infarction lebih sering terjadi pada pria . Kebanyakan faktor risiko untuk penyakit ini adalah hipertensi terkendali .Kata kunci : Penyakit Infark Miokard dengan Elevasi segmen ST, Jantung

scholarly journals Study of the Relationship Between Mean Platelet Volume and LAD as a Culprit Vessel in NSTEMI

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Ahmad Separham ◽  
Alireza Shahsavani ◽  
Ali Heidari Sarvestani
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Mean Platelet Volume ◽  
Complete Blood Count ◽  
St Elevation Myocardial Infarction ◽  
Platelet Volume ◽  
Good Tool ◽  
Cross Sectional ◽  
Significant Difference ◽  
St Elevation

Background: Among acute coronary patients, the ratio of non ST-elevation myocardial infarction (NSTEMI) is increasing and according to recent studies, less than 30% of myocardial infarctions (MIs) are due to ST-elevation myocardial infarction (STEMI). Unlike STEMI, in NSTEMI the ECG is not able to identify the culprit vessel. Objectives: In this study, we aimed to evaluate the association of mean platelet volume (MPV) and NSTEMI due to left anterior descending lesion. Methods: In this cross sectional study 349 patients with NSTEMI were included. Major cardiac risk factors (cigarette, diabetes mellitus (DM), hypertension (HTN), hyperlipidemia (HLP), angiographic findings, and drug history of patients were extracted from patients’ medical files. Then the MPV in complete blood count results and angiography findings were analyzed for any association. According to culprit lesions patients were divided into left anterior descending (LAD) and non-LAD groups. Results: There was a significant difference between the two groups (LAD vs. non-LAD) according to platelet count (P = 0.014), MPV (P = 0.001), HLP (0.024) and DM (0.048). Multivariate regression model has shown the MPV (OR = 0.46, 95%CI = 0.27 - 0.78) and DM (OR = 0.18, 95%CI = 0.06 - 0.54) as independent risk factors for NSTEMI due to LAD lesion. The significant positive correlation was also seen between MPV and left ventricle ejection fraction (LVEF) (r = 0.22, P = 0.006). The area under the curve (AUC) of MPV for predicting LAD culprit lesion was calculated as 69% (P < 0.0001). At cut off point of 9.15, has sensitivity and specificity of MPV for predicting LAD as culprit vessel was 100% and 30% respectively. Conclusions: In NSTEMI patients MPV might be a good tool to differentiate patients with LAD as culprit vessel.

scholarly journals Gambaran Derajat Hipertensi Pada Pasien Sindrom Koroner Akut (SKA) di RSUP PROF. R. D. Kandou Manado Periode Januari - Desember 2014

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Agus Mawardy ◽  
Janry A. Pangemanan ◽  
Dewi Utari Djafar
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Life Style ◽  
St Elevation Myocardial Infarction ◽  
Modifiable Risk Factors ◽  
Cross Sectional ◽  
Coronary Syndrome ◽  
St Elevation

Abstract : Acute Coronary Syndrome (ACS) is an uncomfortable condition or other symptoms in the chest due to lack of oxygen consumption in myocardium. Risk factors of acute coronary syndrome divided to two are modifiable risk factors and non- modifiable risk factors. Modifiable risk factors like hypertension, cholesterol, smoke, obesity, diabetes mellitus, hyperuricemia, physical inactivity, stress and life style. Non- modifiable risk factors like ages, gender, and family history disease. The purpose of this research is to know degree of hypertension and prevalence of hypertension in patient with acute coronary syndrome on RSUP Prof. R. D. Kandou Manado. This research used the observational descriptive method with cross sectional approach. Total sample of this research are 86 patients. The data have been collected by see patient’s medical record. The result showed 86 patient acute coronary syndrome where total of unstable angina pectoris were 47 patients, total of non ST elevation myocardial infarction were 20 patients, and total of ST elevation myocardial infarction were 19 patients. 60 cases were man and 28 cases were woman. 34 cases were pre-hypertension, 43 cases were hypertension stage 1, and 9 cases were hypertension stage 2. The majority of acute coronary syndrome cases were 56-65 years old.Keywords : acute coronary syndrome, degree of hypertensionAbstrak : Sindrom Koroner Akut (SKA) adalah sebuah kondisi yang melibatkan ketidaknyamanan pada dada atau gejala lain yang disebabkan oleh kurangnya oksigen ke otot jantung (miokardium). Faktor risiko SKA dapat dibagi dua yaitu faktor risiko yang dapat bisa diubah (modifiable), yaitu: hipertensi, kolesterol, merokok, obesitas, diabetes mellitus, hiperurisemia, aktivitas fisik kurang, stress, dan gaya hidup (life style). Faktor risiko yang tidak dapat diperbaiki seperti usia, jenis kelamin, dan riwayat penyakit keluarga. Tujuan penelitian ini untuk mengetahui gambaran derajat hipertensi dan prevalensi hipertensi pada pasien Sindrom Koroner Akut (SKA) di RSUP Prof. Dr. R. D kandou Manado. Penelitian ini merupakan jenis penelitian retrospektif observasional, dengan pendekatan cross sectional. Sampel penelitian sebanyak 86 pasien. Pengambilan data dilakukan dengan melihat catatan rekam medik pasien. Hasil penelitian didapatkan 86 penderita sindrom koroner akut dimana jumlah penderita angina pektoris tidak stabil adalah 47 orang, jumlah penderita infark miokard akut tanpa elevasi segmen ST adalah 20 orang, dan jumlah penderita infark miokard akut dengan elevasi segmen ST adalah 19 orang. Penderita sindrom koroner akut yang berjenis kelamin laki-laki adalah 60 orang, sedangkan perempuan berjumlah 26 orang. Terdapat 34 orang yang termasuk didalam pre-hipertensi, 43 orang dengan Hipertensi derajat 1, dan 9 orang termasuk Hipertensi derjat 2. Kelompok usia terbanyak sindrom koroner akut adalah 56-65 tahun.Kata Kunci : Sindrom Koroner Akut, Derajat Hipertensi

scholarly journals Comparison of 25-Hydroxyvitamin D Levels in Acute Coronary Syndrome

2020 ◽  
Vol 26 (3) ◽  
Author(s):  
Mirna Rahmafindari ◽  
Leonita Anniwati ◽  
Muh. Aminuddin ◽  
Ferdy R. Marpaung
Keyword(s):  
Myocardial Infarction ◽  
Vitamin D ◽  
Acute Coronary Syndrome ◽  
St Elevation Myocardial Infarction ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
Coronary Syndrome ◽  
St Elevation ◽  
Cross Sectional Design ◽  
Healthy Persons

Vitamin D deficiency is associated with cardiovascular disease, one of, which is an Acute Coronary Syndrome (ACS). Some studies provide varying results, the 25 (OH)D levels, which can cause acute coronary syndrome is still controversial. This was an observational analytical study with a cross-sectional design. Samples were collected during April-September 2019 from the Dr. Soetomo Hospital, Surabaya. Patients with the acute coronary syndrome (70 persons) consisted of ST-Elevation Myocardial Infarction (STEMI), non-ST-Elevation Myocardial Infarction (NSTEMI), Unstable Angina (UA) were measured for 25 (OH)D and the differences in levels of 25 (OH)D between groups. Examination of 25 (OH)D used a competitive antibody method chemiluminescence immunoassay. There were different levels of 25 (OH)D patients with ACS versus healthy persons, p=0.0001. There was no difference in levels of 25 (OH)D in UA patients versus healthy persons, p=0.925. Acute coronary syndrome patients had higher 25 (OH)D levels than healthy persons, so it seemed that vitamin D did not play an essential role in the occurrence of ACS based on this study. This study showed that there were significant differences between 25 (OH)D levels in STEMI and healthy persons, NSTEMI and healthy persons, STEMI and NSTEMI, STEMI and UA, NSTEMI and UA. In the UA group and healthy persons, no statistically significant differences were found.

Risk factors of coronary microvascular obstruction (Preprint)

2020 ◽  
Author(s):  
Yong Li ◽  
Shuzheng Lyu
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Logistic Regression ◽  
Microvascular Obstruction ◽  
Coronary Intervention ◽  
St Elevation Myocardial Infarction ◽  
Neutrophil Percentage ◽  
Percutaneous Coronary ◽  
St Elevation

BACKGROUND Coronary microvascular obstruction /no-reflow(CMVO/NR) is a predictor of long-term mortality in survivors of ST elevation myocardial infarction (STEMI) underwent primary percutaneous coronary intervention (PPCI). OBJECTIVE To identify risk factors of CMVO/NR. METHODS Totally 2384 STEMI patients treated with PPCI were divided into two groups according to thrombolysis in myocardial infarction(TIMI) flow grade:CMVO/NR group(246cases,TIMI 0-2 grade) and control group(2138 cases,TIMI 3 grade). We used univariable and multivariable logistic regression to identify risk factors of CMVO/NR. RESULTS A frequency of CMVO/NR was 10.3%(246/2384). Logistic regression analysis showed that the differences between the two groups in age(unadjusted odds ratios [OR] 1.032; 95% CI, 1.02 to 1.045; adjusted OR 1.032; 95% CI, 1.02 to 1.046 ; P <0.001), periprocedural bradycardia (unadjusted OR 2.357 ; 95% CI, 1.752 to 3.171; adjusted OR1.818; 95% CI, 1.338 to 2.471 ; P <0.001),using thrombus aspirationdevices during operation (unadjusted OR 2.489 ; 95% CI, 1.815 to 3.414; adjusted OR1.835; 95% CI, 1.291 to 2.606 ; P =0.001),neutrophil percentage (unadjusted OR 1.028 ; 95% CI, 1.014 to 1.042; adjusted OR1.022; 95% CI, 1.008 to 1.036 ; P =0.002) , and completely block of culprit vessel (unadjusted OR 2.626; 95% CI, 1.85 to 3.728; adjusted-OR 1.656;95% CI, 1.119 to 2.45; P =0.012) were statistically significant ( P <0. 05). The area under the receiver operating characteristic curve was 0.6896 . CONCLUSIONS Age , periprocedural bradycardia, using thrombus aspirationdevices during operation, neutrophil percentage ,and completely block of culprit vessel may be independent risk factors for predicting CMVO/NR. We registered this study with WHO International Clinical Trials Registry Platform (ICTRP) (registration number: ChiCTR1900023213; registered date: 16 May 2019).http://www.chictr.org.cn/edit.aspx?pid=39057&htm=4. Key Words: Coronary disease ST elevation myocardial infarction No-reflow phenomenon Percutaneous coronary intervention

scholarly journals DIFFERENTIAL CELL COUNT AS DIAGNOSTIC AND PROGNOSTIC MARKER OF ACUTE MYOCARDIAL INFARCTION

2018 ◽  
Vol 24 (2) ◽  
pp. 175
Author(s):  
Sri Anita ◽  
Liong Boy Kurniawan ◽  
Darwati Muhadi
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cell Count ◽  
Inflammatory Marker ◽  
St Elevation Myocardial Infarction ◽  
Chi Square ◽  
Cross Sectional ◽  
Differential Cell Count ◽  
Differential Cell ◽  
St Elevation

Myocardial infarction is a necrosis of myocardial cells due to lack of blood and oxygen supply caused by obstruction of coronary arteries, mostly due to atherosclerosis processes. Increased inflammatory marker level is associated with poor cardiovascular prognosis. This study was aimed to know whether leukocytes count, differential cell count and the Ratio of Neutrophils-Lymphocytes (RNL) could distinguish between types of Acute Myocardial Infarction (AMI) and to evaluate its correlation with mortality. This was a cross-sectional retrospective study using medical records patients which were diagnosed as AMI by clinicians in Cardiac Centre of the Dr. Wahidin Sudirohusodo Hospital during the period of April 1st, 2015 - May 31st, 2016. Statistical analysis used the Mann-Whitney and Chi-Square test, p<0.05 was considered as significant. The total subjects were 435 patients divided into 289 ST- Elevation Myocardial Infarction (STEMI) and 146 Non-ST-Elevation Myocardial Infarction (NSTEMI). There were significant differences in that mean of leukocytes, neutrophils, lymphocytes, monocytes, eosinophils counts and RNL between STEMI and NSTEMI (p <0.05). Significant differences were also found in leukocyte, neutrophils, lymphocytes, eosinophils, basophils and RNL mean between those who died and survived (p <0.05) and a significant correlation between increased leukocytes, neutrophils, basophils counts with mortality (p <0.05). In conclusion, the number of leukocytes and leukocyte count can be used as diagnostic markers of AMI between STEMI and NSTEMI, as well as prognostic markers among patients who died and survived. Routine blood sampling cohort studies in patients with AMI can avoid the bias of the results obtained. 

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