scholarly journals Innovative medicine of Kuban

2019 ◽  
Keyword(s):  
2017 ◽  
Vol 20 (9) ◽  
pp. A691
Author(s):  
G Kockaya ◽  
FB Yenilmez ◽  
A Sharaf ◽  
H Ammar
Keyword(s):  

2017 ◽  
Vol 158 (6) ◽  
pp. 220-228
Author(s):  
Viktória Fésüs ◽  
Dóra Marosvári ◽  
Béla Kajtár ◽  
Péter Attila Király ◽  
Judit Demeter ◽  
...  

Abstract: Introduction: In recent years much progress has been made in the therapy of chronic lymphocytic leukaemia, as the new innovative medicine proved to be effective in managing patients carrying TP53 abnormalities. To identify all these patients, it is essential to screen for both forms of TP53 defects, including both 17p deletions and TP53 mutations. Aim: The aim of this study was to determine the frequency of TP53 mutations and their association with 17p deletions in a large Hungarian cohort of 196 patients suffering from chronic lymphocytic leukaemia. Method: We performed mutation analysis of TP53 (exons 3–10) using Sanger sequencing. Results: TP53 mutations were present in 15.8% of patients, half of which were associated with 17p deletion. By analysing both forms, TP53 defect was identified in 25.4% of the patients. Conclusions: Our study demonstrates that by performing a TP53 mutation analysis, an additional 10% of high-risk patients can be detected. Orv. Hetil., 2017, 158(6), 220–228.


2013 ◽  
Vol 1 (1) ◽  
pp. 13-18
Author(s):  
Maryline Margueritte

For several years, health networks have developed devices enabling coordinated care of patients in France, regarding both medical plans as well as medico-psycho-social and human care. Some have developed computerized health records for sharing useful information for the coordination and continuity of care. Since the 2009 hospital reform, cooperative operating modes between health system professionals and users are being installed. The implementation of a health information system permits, on one hand, to ensure the transversality of the business process with the patient and, on the other hand, to measure the results of the medical and economic evolution of a complex system of information. The possibilities offered by new technologies of information and communication enable the development of applications supporting increased "on line" participation for citizens. The "ambulatory approach" exports healthcare outside hospital walls. This is an innovative medicine allowing the patient to stay at his home. In France, this re-engineering is based on four areas: a medical record, a collective ownership by the medical and paramedical professions, empowerment of patients and networking in the health sector.Keywords: Health; Networks; Information System; Innovation; Medicine; Patients; Science.


2017 ◽  
Vol 235 ◽  
pp. 1-6 ◽  
Author(s):  
Kristina Kristinaitytė ◽  
Laurynas Dagys ◽  
Jonas Kausteklis ◽  
Vytautas Klimavicius ◽  
Iryna Doroshenko ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document