scholarly journals INFLUENCE OF KINESITHERAPY ON PATIENTS WITH DIABETIC POLYNEUROPATHY

2019 ◽  
Vol 34 (4) ◽  
pp. 1015-1021
Author(s):  
Antonija Jakimovska ◽  
Danche Vasileva
Keyword(s):  
Diabetic Polyneuropathy ◽  
Test Methods ◽  
Diagnostic Methods ◽  
Motor Neuropathy ◽  
High Prevalence ◽  
Sensory Motor ◽  
Balance Deficits ◽  
Vibrational Sensitivity ◽  
Major Factors ◽  
Chronic Hyperglycaemia

Diabetes tends to increase steadily, and is one of the most common endocrinological diseases. This disease has a high prevalence, and the incidence is increasing every year both in the world and in our country. There are several risk factors for DMD, but the main risk factor is low glycemic control (chronic hyperglycaemia). With each increase in glycated hemoglobin by 1%, the chances of developing DMD are increased. Age is also one of the major factors (the longer the DM lasts, the greater the chances of developing diabetic polyneuropathy).The causes of diabetic polyneuropathy may be known, hereditary or non-hereditary, but sometimes the causes remain unknown. The aim is to study the effectiveness of a kinesiotherapy method, based on modern principles of neurorehabilitation in improving the functional status of patients with diabetic polyneuropathy. Patients were selected according to several criteria in order to have homogeneity of the study: to be between 40 and 60 years of age; have type 2 diabetes diagnosed; have diagnosed diabetic polyneuropathy - distal symmetric sensory motor neuropathy of the lower extremities; not have severe cardiovascular and respiratory insufficiency as well as severe cognitive impairment; have stable hemodynamics, and arterial pressure is below 160/95; to move without auxiliary means. The subjects were treated with a specialized kinesiotherapy method based on the modern principles of neurorehabilitation in DPN. For the purposes of the study, a complex set of diagnostic methods is applied, and the results from which are evaluated on day 1, day 10, and month 1 of treatment are shown in a worksheet. For the purpose of the study, a complex set of diagnostic methods is applied, and the results from which are evaluated on day 1, day 10 and month 1 of treatment are shown in a worksheet.Assessed: sensory capabilities with peripheral sensitivity test (pain) and deep sensitivity (discriminatory and vibrational sensitivity) motor capabilities with manual muscle test (MMT) and centimeter and equilibrium abilities with single leg test. Results and Discussion: The presented results provide an opportunity to analyze the effect of applied kinesiotherapy. For this purpose, follow-up of various evaluated parameters was performed at baseline, on day 10 and on month 1 of treatment. This design is respected in all patients with PDD included in the study. The specialized kinesiology method stabilizes the permanently functional motor revascularization and equilibration potential of patients with PDD. Conclusion: This is a complex study of the potential of kinesiotherapy to overcome sensory, motor, and balance deficits in continued outpatient treatment of patients with PDD. It has been carried out with modern test methods, which give the opportunity to evaluate the changes in the parameters examined, in terms of sensory, motor and equilibrium possibilities after specialized kinesiotherapy. The presence of positive change in all functional parameters was observed after the administration of specialized kinesiotherapy in all subjects.

scholarly journals Non-invasive diagnostic methods of the liver fibrosis in patients with overweigh and obesity

2021 ◽  
Vol 11 (3) ◽  
pp. 239-245
Author(s):  
Nadiia Gavryliuk ◽  
Ihor Hospodarskyy ◽  
Oksana Prokopchuk ◽  
Olga Namisniak ◽  
Mykhailo Havrylyuk
Keyword(s):  
Liver Fibrosis ◽  
Wide Distribution ◽  
Modern Medicine ◽  
Overweight And Obesity ◽  
Hcv Infection ◽  
Diagnostic Methods ◽  
Non Invasive ◽  
Number Of Patients ◽  
High Prevalence ◽  
Rate Of Progression

One of the biggest problems of modern medicine is the difficulty in early diagnostic and effective treatment of HCV infection due to its wide distribution, latent form and terrible consequences as a formation of liver cirrhosis (CP) and hepatocellular carcinoma (HCC). It is important to mention, that the rate of progression of liver fibrosis. It is an important medical and social problem that the number of patients with NAFLD, overweight and obesity is constantly increases [9]. Due to the high prevalence of NAFLD and CHC, these two pathologies will progress and contribute to the progression of fibrosis, and depending on the genome of the virus and metabolic syndrome. There is a high risk of developing CP and HCC even after achieving a stable virological response.The main aim of our investigation was to assess the stages of fibrosis by using non-invasive methods for patients with overweight and obesity who being treated for HCV infection (with posthepatic fibrosis).

Juvenile Leigh syndrome with protracted course presenting as chronic sensory motor neuropathy, ataxia, deafness and retinitis pigmentosa: a clinicopathological report

1998 ◽  
Vol 155 (2) ◽  
pp. 218-221 ◽  
Author(s):  
Alessandro Malandrini ◽  
Silvia Palmeri ◽  
Gian Maria Fabrizi ◽  
Marcello Villanova ◽  
Gianna Berti ◽  
...  
Keyword(s):  
Retinitis Pigmentosa ◽  
Leigh Syndrome ◽  
Motor Neuropathy ◽  
Sensory Motor

Glycemic Control and Clinico-Electrophysiological Severity of Diabetic Polyneuropathy

2019 ◽  
Vol 5 (2) ◽  
pp. 177-184
Author(s):  
KM Nazmul Islam Joy ◽  
ATM Hasibul Hasan ◽  
Md Rafiqul Islam ◽  
Farhana Kalam ◽  
M Lutful Kabir ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Diabetic Neuropathy ◽  
Nerve Conduction ◽  
Scoring System ◽  
Diabetic Polyneuropathy ◽  
Nerve Conduction Studies ◽  
Clinical Severity ◽  
Diabetic Patients ◽  
Motor Neuropathy ◽  
Clinical Scoring

Background: Diabetic polyneuropathy (DPN) has a significant positive correlation with poor glycemic control (HbA1c ≥7%). The clinical, biochemical and electrophysiological parameters of DPN in Bangladeshi citizens have not yet been explored elaborately Objective: The purpose of the study was to detect and categorize status of glycemic control of Bangladeshi people and to analyze its impact on clinical severity of DPN using Toronto Clinical Scoring System (TCSS) and electrophysiological severity by modified Michigan diabetic neuropathy score (MDNS). Methodology: This observational study was carried out on diabetic patients having probable DPN by purposive sampling, attending Neurology OPD of Dhaka Medical College Hospital, Dhaka, Bangladesh and Bangladesh Institute of Research & Rehabilitation in Diabetes, Endocrine & Metabolic Disorder (BIRDEM) Hospital, Dhaka, Bangladesh from July 2014 to June 2016. Clinical parameters were recorded and DPN was graded as “no neuropathy”, “mild”, “moderate” and “severe” neuropathy by the Toronto Clinical Scoring System (TCSS). A standard nerve conduction study was performed on each patient and electrophysiological grading according to modified Michigan diabetic neuropathy score (MDNS) was done. Diabetic status of patients was classified into “controlled” (HbA1c <7.0%) and “uncontrolled” (HbA1c ≥7.0%) groups and HbA1c level and the clinical & electrophysiological severity scores were compared and were analyzed. Results: Mean age of the patients was 57.2±9.37 years. 51.0% cases were males and 49% cases were females. The mean HbA1c in the study population was 7.6±0.94% and 56.0% patients had HbA1c≥ 7% .Motor nerve conduction studies revealed that both CMAP amplitudes and MNCV in the ulnar, peroneal and tibial nerves were reduced significantly in patients of uncontrolled (HbA1c≥7%) DM (p<0.001). Sensory nerve conduction studies revealed significant reduction in SNAP amplitudes of median and ulnar sensory and sural nerves in the uncontrolled group (p<0.001). Electrophysiologically, 65.43% patients had mixed sensory-motor neuropathy (p<0.00001). Clinically severe DPN patients were higher (45.2%) within the uncontrolled (HbA1C ≥7%) group (p<0.00001). Similarly, severity in electrophysiological grading was more in patients with uncontrolled DM (48.8%) (p<0.00001). Conclusions: Neuropathic severity, either clinically or electrophysiologically, was associated with higher values of HbA1c. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 177-184

scholarly journals A recent update of the diagnostic methods for tuberculosis and their applicability in Indonesia: a narrative review

2019 ◽  
Vol 28 (3) ◽  
pp. 284-91
Author(s):  
Tri Nugraha Susilawati ◽  
Riska Larasati
Keyword(s):  
Delayed Diagnosis ◽  
Diagnostic Methods ◽  
World Health ◽  
Current State ◽  
Interferon Gamma Release Assays ◽  
High Prevalence ◽  
The World ◽  
Golden Standard ◽  
Tertiary Hospitals ◽  
Health Organization

Tuberculosis (TB) is a major global problem, especially with the high prevalence of HIV-TB co-infection. Delayed diagnosis and continual transmission contribute to high mortality in Indonesia, which has the third highest incidence of TB in the world, after China and India. Therefore, early diagnosis is needed to reduce the number of cases and to administer therapy to prevent the transmission of bacteria. The diagnosis of TB remains a challenge in clinical practice due to poor sensitivity and the requirement of skilled staff in microscopic tests, the slow growth Mycobacterium in culture, and the low number of bacilli present in extrapulmonary TB. Despite being the golden standard for TB diagnosis, cultures require 2–8 weeks to grow. Other methods for diagnosing TB include interferon-gamma release assays and serologic tests such as the tuberculin skin test. Recently, the World Health Organization recommended the GeneXpert MTB/RIF assay for diagnosing TB. This review presents the current state of TB epidemiology and various methods for TB diagnosis. In particular, the paper provides an in-depth discussion about the GeneXpert MTB/RIF assay that has been made available recently in selected tertiary hospitals in Indonesia.

Axonal sensory motor neuropathy in copper-deficient Wilson's disease

2009 ◽  
Vol 40 (2) ◽  
pp. 294-296 ◽  
Author(s):  
Alexandra Foubert-Samier ◽  
Annabelle Kazadi ◽  
Marie Rouanet ◽  
Anne Vital ◽  
Alain Lagueny ◽  
...  
Keyword(s):  
Wilson’S Disease ◽  
Wilson's Disease ◽  
Motor Neuropathy ◽  
Sensory Motor

scholarly journals The effects of isometric exercises and stretching on postural stability in Non–Insulin Dependent Diabetes Mellitus patients with diffuse symmetrical sensory motor neuropathy

2009 ◽  
Vol 65 (2) ◽  
Author(s):  
S. Nenkova ◽  
A. Stewart ◽  
J. Potterton ◽  
P. Becker
Keyword(s):  
Diabetes Mellitus ◽  
Postural Stability ◽  
Insulin Dependent Diabetes Mellitus ◽  
Dependent Diabetes Mellitus ◽  
Control Group ◽  
Motor Neuropathy ◽  
Sensory Motor ◽  
Insulin Dependent ◽  
Experimental Group ◽  
Niddm Patients

The purpose of this study was to explore the effects of isometric exercises and stretching on postural stability in Non – Insulin Dependent Diabetes Mellitus (NIDDM) patients with diffuse symmetrical sensory motor neuropathy. Patients were assigned to an experimental group and amatched control group. The experimental group received isometric exer-cises and stretching three times weekly for 12 weeks in addition to routine medication and dietary advice. A t the end of this period, this group wascompared with the control group, which received routine medication anddietary advice only. Measurements of muscle strength of quadriceps, ham-strings, ankle plantar and dorsiflexors, and Romberg’s test for postural sta-bility were carried out before and after the 12 weeks intervention. The study showed that isometric exercises and stretching for the lower extremities improved postural stability (p = 0.00)and strength of the quadriceps (p = 0.001) hamstrings (p = 0.001) dorsiflexors (p = 0.001) plantarflexors (p = 0.001)in NIDDM patients with diffuse symmetrical sensory motor neuropathy. This exercise regimen also had a loweringeffect on blood glucose level (p = 0.00).  In conclusion it seems that the simple exercise intervention described in thisstudy may be of benefit to these patients if incorporated into their management programmes.

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