Exposure to dim light at night hastens human breast cancer tumor cells' growth

2019 ◽  
Author(s):  
Editage Insights
Neoplasia ◽  
2009 ◽  
Vol 11 (10) ◽  
pp. 1106-1115 ◽  
Author(s):  
Francesca Margheri ◽  
Simona Serratì ◽  
Andrea Lapucci ◽  
Chillà Anastasia ◽  
Betti Giusti ◽  
...  

2012 ◽  
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Antonia Patsialou ◽  
Yarong Wang ◽  
Juan Lin ◽  
Kathleen Whitney ◽  
Sumanta Goswami ◽  
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Vol 103 (1) ◽  
pp. 129-129
Author(s):  
Yingchao Zhang ◽  
Yu Wang ◽  
Wenxin Gao ◽  
Ruhui Zhang ◽  
Xichun Han ◽  
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2011 ◽  
Vol 71 (7) ◽  
pp. 2622-2631 ◽  
Author(s):  
Jinghai Wu ◽  
Robert T. Dauchy ◽  
Paul C. Tirrell ◽  
Steven S. Wu ◽  
Darin T. Lynch ◽  
...  

2021 ◽  
Author(s):  
Shahan Mamoor

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). Between the brain and the breast resides the secondary lymphoid organ, the lymph nodes. We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with metastasis to the lymph nodes in human breast cancer. We found that the SP140 nuclear body protein like, encoded by SP140L, was among the genes whose expression was most different in the lymph nodes metastases of patients with metastatic breast cancer as compared to primary tumors of the breast (4). SP140L was also differentially expressed in the tumor cells of patients with triple negative breast cancer (5). SP140L mRNA was present at increased quantities in lymph node metastatic tissues as compared to primary tumors of the breast. Importantly, expression of SP140L in primary tumors was significantly correlated with patient overall survival, in lymph node positive patients but not in lymph node negative patients. Modulation of SP140L expression may be relevant to the biology by which tumor cells metastasize from the breast to the lymph node and to the brain in humans with metastatic breast cancer.


2021 ◽  
Author(s):  
Shahan Mamoor

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). Between the brain and the breast resides the secondary lymphoid organ, the lymph nodes. We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with metastasis to the lymph nodes in human breast cancer. We found that the coiled-coil domain containing 155, encoded by CCDC155, was among the genes whose expression was most different in the lymph nodes metastases of patients with metastatic breast cancer as compared to primary tumors of the breast (4). CCDC155 was also differentially expressed in the tumor cells of patients with triple negative breast cancer (5). CCDC155 mRNA was present at increased quantities in lymph node metastatic tissues as compared to primary tumors of the breast. Importantly, expression of CCDC155 in primary tumors was significantly correlated with patient recurrence-free survival, in lymph node positive patients but in lymph node negative patients. Modulation of CCDC155 expression may be relevant to the biology by which tumor cells metastasize from the breast to the lymph node and to the brain in humans with metastatic breast cancer.


2000 ◽  
Vol 157 (5) ◽  
pp. 1713-1725 ◽  
Author(s):  
Benedetta Bussolati ◽  
Luigi Biancone ◽  
Paola Cassoni ◽  
Simona Russo ◽  
Marek Rola-Pleszczynski ◽  
...  

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