The effect of high intensity interval training on SIRT1 and PGC1-α gene expression in soleus muscle of type 2 diabetes in male rat

2020 ◽  
Vol 42 (4) ◽  
pp. 447-455
Author(s):  
mahsa mohsenzadeh ◽  
fariba aghaei ◽  
farah nameni
Keyword(s):  
Gene Expression ◽  
Type 2 Diabetes ◽  
Soleus Muscle ◽  
High Intensity ◽  
Interval Training ◽  
Male Rat ◽  
High Intensity Interval Training ◽  
High Intensity Interval

553-P: Differential Effects of High-Intensity Interval Training on Somatosensory and Autonomic Nerve Function in Patients with Type 2 Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 553-P
Author(s):  
GIDON J. BÖNHOF ◽  
ALEXANDER STROM ◽  
MARIA APOSTOLOPOULOU ◽  
DOMINIK PESTA ◽  
MICHAEL RODEN ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
High Intensity ◽  
Interval Training ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
High Intensity Interval Training ◽  
Differential Effects ◽  
Autonomic Nerve Function ◽  
High Intensity Interval

scholarly journals Anthropometric, Cardiopulmonary and Metabolic Benefits of the High-Intensity Interval Training Versus Moderate, Low-Intensity or Control for Type 2 Diabetes: Systematic Review and Meta-Analysis

2019 ◽  
Vol 16 (22) ◽  
pp. 4524 ◽  
Author(s):  
Lora-Pozo ◽  
Lucena-Anton ◽  
Salazar ◽  
Galán-Mercant ◽  
Moral-Munoz
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Body Mass ◽  
High Intensity ◽  
Meta Analysis ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval ◽  
Intensity Training

Abstract: This study aims to evaluate the effectiveness of high-intensity interval training compared with no intervention and other types of training interventions for people with Type 2 Diabetes. A systematic review and meta-analysis of randomized controlled trials that used high-interval intensity training to improve anthropometric, cardiopulmonary and metabolic conditions were conducted. The search was performed during October–December 2017 using the databases PubMed, Web of Science and Physiotherapy Evidence Database (PEDro). The methodological quality of the studies was evaluated using the PEDro scale. A total of 10 articles were included in this meta-analysis. After statistical analysis, favorable results were obtained for high-Intensity Interval Training compared with control (non-intervention): [Weight: Standardized mean difference (SMD) = −2.09; confidence interval (CI) 95%: (−3.41; −0.78); body-mass index: SMD = −3.73; CI 95%: (−5.53; −1.93); systolic blood pressure: SMD = −4.55; CI 95%: (−8.44; −0.65); VO2max: SMD = 12.20; CI 95%: (0.26; 24.14); HbA1c: SMD = −3.72; CI 95%: (−7.34; −0.10)], moderate intensity continuous training: [body-mass index: SMD = −0.41; CI 95%: (−0.80; −0.03); VO2max: SMD = 1.91; CI 95%: (0.18; 3.64)], and low intensity training: [Weight: SMD = −2.06; CI 95%: (−2.80; −1.31); body-mass index: SMD = −3.04; CI 95%: (−5.16; −0.92); systolic blood pressure: SMD = −2.17; CI 95%: (−3.93; −0.41); HbA1c: SMD = −1.58; CI 95%: (−1.84; −1.33)]. The results show that high-intensity interval training can be a useful strategy in order to improve anthropometric, cardiopulmonary and metabolic parameters in people with Type 2 diabetes. Despite this, it could be essential to clarify and unify criteria in the intervention protocols, being necessary new lines of research.

Effects of one‐legged high‐intensity interval training on insulin‐mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes

2019 ◽  
Vol 226 (2) ◽  
pp. e13245 ◽  
Author(s):  
Flemming Dela ◽  
Arthur Ingersen ◽  
Nynne B. Andersen ◽  
Maria B. Nielsen ◽  
Helga H. H. Petersen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Skeletal Muscle ◽  
Glucose Homeostasis ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

scholarly journals Timing of Exercise Affects Glycemic Control in Type 2 Diabetes Patients Treated with Metformin

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Tao Huang ◽  
Chunyan Lu ◽  
Moritz Schumann ◽  
Shenglong Le ◽  
Yifan Yang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Superoxide Dismutase ◽  
Glycemic Control ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Acute Effects ◽  
Sod Activity ◽  
High Intensity Interval

Objective. The purpose of the study was to examine the acute effects of the timing of exercise on the glycemic control during and after exercise in T2D. Methods. This study included 26 T2D patients (14 women and 12 men) who were treated with metformin. All patients were tested on four occasions: metformin administration alone (Metf), high-intensity interval training (HIIT) performed at 30 minutes (EX30), 60 minutes (EX60), and 90 minutes (EX90) postbreakfast, respectively. Glucose, insulin, and superoxide dismutase (SOD) activity were examined. Results. Glucose decreased significantly after the exercise in EX30, EX60, and EX90. Compared with Metf, the decline in glucose immediately after the exercise was larger in EX30 (−2.58 mmol/L; 95% CI, −3.36 to −1.79 mmol/L; p<0.001), EX60 (−2.13 mmol/L; 95% CI, −2.91 to −1.34 mmol/L; p<0.001), and EX90 (−1.87 mmol/L; 95% CI, −2.65 to −1.08 mmol/L; p<0.001), respectively. Compared with Metf, the decrease in insulin was larger in EX30 and EX60 (both p<0.001). Conclusions. Timing of exercise is a factor to consider when prescribing exercise for T2D patients treated with metformin. This trial is registered with ChiCTR-IOR-16008469 on 13 May 2016.

High-intensity interval training reduces abdominal fat mass in postmenopausal women with type 2 diabetes

2016 ◽  
Vol 42 (6) ◽  
pp. 433-441 ◽  
Author(s):  
F. Maillard ◽  
S. Rousset ◽  
B. Pereira ◽  
A. Traore ◽  
P. de Pradel Del Amaze ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Postmenopausal Women ◽  
Fat Mass ◽  
High Intensity ◽  
Interval Training ◽  
Abdominal Fat ◽  
High Intensity Interval Training ◽  
High Intensity Interval

It's Not Too Hard! Perceived Enjoyment for High-intensity Interval Training in Type 2 Diabetes

2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 20 ◽  
Author(s):  
Mary E. Jung ◽  
Jonathan P. Little ◽  
Jenna Gillen ◽  
Zubin Punthakee ◽  
Martin J. Gibala
Keyword(s):  
Type 2 Diabetes ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Perceived Enjoyment ◽  
High Intensity Interval

scholarly journals High-Intensity Interval Training Improves Cardiac Autonomic Function in Patients with Type 2 Diabetes: A Randomized Controlled Trial

Biology ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 66
Author(s):  
Lucas Raphael Bento Silva ◽  
Paulo Gentil ◽  
Camila Simões Seguro ◽  
Jordana Campos Martins de Oliveira ◽  
Maria Sebastiana Silva ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
High Intensity ◽  
Interval Training ◽  
Moderate Intensity ◽  
Autonomic Modulation ◽  
High Intensity Interval Training ◽  
Passive Recovery ◽  
Group Time ◽  
High Intensity Interval

Different exercise models have been used in patients with type 2 diabetes mellitus (T2D), like moderate intensity continuous training (MICT) and high intensity interval training (HIIT); however, their effects on autonomic modulation are unknown. The present study aimed to compare the effects of different exercise modes on autonomic modulation in patients with T2D. In total, 44 adults with >5 years of T2D diagnosis were recruited and stratified into three groups: HIIT-30:30 (n = 15, age 59.13 ± 5.57 years) that performed 20 repetitions of 30 s at 100% of VO2peak with passive recovery, HIIT-2:2 (n = 14, age 61.20 ± 2.88) that performed 5 repetitions of 2 min at 100% of VO2peak with passive recovery, and MICT (n = 15, age 58.50 ± 5.26) that performed 14 min of continuous exercise at 70% of VO2peak. All participants underwent anamnesis and evaluation of cardiorespiratory fitness and cardiac autonomic modulation. All protocols were equated by total distance and were performed two times per week for 8 weeks. Group × time interactions were observed for resting heart rate (HRrest) [F(2.82) = 3.641; p = 0.031] and SDNN [F(2.82) = 3.462; p = 0.036]. Only the HIIT-30:30 group significantly reduced SDNN (p = 0.002 and 0.025, respectively). HRrest reduced more in the HIIT-30:30 group compared with the MICT group (p = 0.038). Group × time interactions were also observed for offTAU [F(2.82) = 3.146; p = 0.048] and offTMR [F(2.82) = 4.424; p = 0.015]. The MICT group presented increased values of offTAU compared with the HIIT-30:30 and HIIT-2:2 groups (p = 0.001 and 0.013, respectively), representing a slower HR response after eight weeks of intervention. HIIT, specially HIIT-30:30, represents a promising measure for improving autonomic modulation in patients with T2D.

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