scholarly journals Association of urinary triclosan and methyl-triclosan levels with predictive indicators of cardiovascular disease and obesity in children and adolescents in 2020 (case study: Kerman, Iran)

2021 ◽  
Vol 8 (3) ◽  
pp. 187-195
Author(s):  
Habibeh Nasab ◽  
Moghaddameh Mirzaee ◽  
Karim Ebrahimpour ◽  
Majid Hashemi
Keyword(s):  
Children And Adolescents ◽  
Significant Relationship ◽  
Endocrine Disrupting Chemicals ◽  
Anthropometric Parameters ◽  
Methyl Triclosan ◽  
Endocrine Disrupting ◽  
Unit Increase ◽  
Background Exposure ◽  
Study Population ◽  
Predictive Indicators

Background: Exposure of children and adolescents to endocrine disrupting chemicals (EDCs) causes the development of non-communicable diseases. Triclosan (TCS) is a fat-soluble antimicrobial agent, and methyl-triclosan (MTCS) is the predominant metabolite of TCS. The increasing use of consumables TCS (toothpaste, mouthwash, personal care products) in human has raised concerns about human health. Methods: The urinary concentrations of TCS and MTCS were measured by GC/MS. Lipid profiles (TG, TC, LDL, and HDL), anthropometric parameters (WC, BMI z-score, and BMI), FBS, SBP, and DBP tests were performed on 79 children and adolescents. Results: Of 79 people included as the study population, 42 subjects (53.16%) were males. Most of the study population as 32 subjects (40.50%) were obese. The mean concentrations of TCS and MTCS in the obese population were 5.47 ± 2.99 and 2.32 ± 1.04 µg/L, respectively. After adjusting for possible confounding factors, the results showed that a one-unit increase in DBP caused a 0.03 units increase in TCS levels in male subjects (P=0.01). A one-unit increase in DBP also caused a 0.02 units increase in MTCS (P=0.001). There was a significant relationship between TCS and HDL (OR=0.90, P=0.005), LDL (OR=1.13, P=0.01), and TG (OR =1.05, P<0.0001). There was also a significant relationship between MTCS and HDL (OR=0.88, P=0.001), LDL (OR=1.03, P=0.009), and TG (OR=1.04, P < 0.0001). Conclusion: According to the results, there is a relationship between TCS, MTCS, and predictive indicators of cardiovascular diseases and obesity.

scholarly journals Endocrine-Disrupting Chemicals and Insulin Resistance in Children

Biomedicines ◽  
2020 ◽  
Vol 8 (6) ◽  
pp. 137 ◽  
Author(s):  
Eleonora Rotondo ◽  
Francesco Chiarelli
Keyword(s):  
Insulin Resistance ◽  
Bisphenol A ◽  
Prospective Studies ◽  
Endocrine Disrupting Chemicals ◽  
Experimental Studies ◽  
Epidemiological Studies ◽  
Cross Sectional ◽  
Obesity And Diabetes ◽  
Endocrine Disrupting ◽  
Background Exposure

The purpose of this article is to review the evidence linking background exposure to endocrine-disrupting chemicals (EDCs) with insulin resistance in children. Although evidence in children is scarce since very few prospective studies exist even in adults, evidence that EDCs might be involved in the development of insulin resistance and related diseases such as obesity and diabetes is accumulating. We reviewed the literature on both cross-sectional and prospective studies in humans and experimental studies. Epidemiological studies show a statistical link between exposure to pesticides, polychlorinated bisphenyls, bisphenol A, phthalates, aromatic polycyclic hydrocarbides, or dioxins and insulin resistance.

Effect of Polyphosphate on Removal of Endocrine-Disrupting Chemicals of Nonylphenol and Bisphenol-A by Activated Carbons

2005 ◽  
Vol 40 (4) ◽  
pp. 484-490 ◽  
Author(s):  
Keun J. Choi ◽  
Sang G. Kim ◽  
Chang W. Kim ◽  
Seung H. Kim
Keyword(s):  
Activated Carbon ◽  
Bisphenol A ◽  
Surface Charge ◽  
Activated Carbons ◽  
Endocrine Disrupting Chemicals ◽  
Dipole Interaction ◽  
High Affinity ◽  
Calcium Polyphosphate ◽  
Endocrine Disrupting ◽  
Positively Charged

Abstract This study examined the effect of polyphosphate on removal of endocrine-disrupting chemicals (EDCs) such as nonylphenol and bisphenol-A by activated carbons. It was found that polyphosphate aided in the removal of nonylphenol and bisphenol- A. Polyphosphate reacted with nonylphenol, likely through dipole-dipole interaction, which then improved the nonylphenol removal. Calcium interfered with this reaction by causing competition. It was found that polyphosphate could accumulate on carbon while treating a river. The accumulated polyphosphate then aided nonylphenol removal. The extent of accumulation was dependent on the type of carbon. The accumulation occurred more extensively with the wood-based used carbon than with the coal-based used carbon due to the surface charge of the carbon. The negatively charged wood-based carbon attracted the positively charged calcium-polyphosphate complex more strongly than the uncharged coal-based carbon. The polyphosphate-coated activated carbon was also effective in nonylphenol removal. The effect was different depending on the type of carbon. Polyphosphate readily attached onto the wood-based carbon due to its high affinity for polyphosphate. The attached polyphosphate then improved the nonylphenol removal. However, the coating failed to attach polyphosphate onto the coal-based carbon. The nonylphenol removal performance of the coal-based carbon remained unchanged after the polyphosphate coating.

scholarly journals Endocrine disrupting chemicals mixture and pregnancy glucose levels among women from a fertility clinic

2019 ◽  
Vol 3 ◽  
pp. 27
Author(s):  
Bellavia A ◽  
Mínguez-Alarcón L ◽  
Ford J ◽  
Keller M ◽  
Petrozza J ◽  
...  
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Glucose Levels ◽  
Endocrine Disrupting ◽  
Fertility Clinic

Endocrine disrupting chemicals and reproductive disorders in women, men, and animal models

2021 ◽  
Author(s):  
Mary Jo Laws ◽  
Alison M. Neff ◽  
Emily Brehm ◽  
Genoa R. Warner ◽  
Jodi A. Flaws
Keyword(s):  
Animal Models ◽  
Endocrine Disrupting Chemicals ◽  
Reproductive Disorders ◽  
Endocrine Disrupting
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