Studies on bacterial mutation using streptomycin-dependent tubercle bacilli

1958 ◽  
Vol 13 (3) ◽  
pp. 201-203
Author(s):  
Koomi KANAI ◽  
Shigeru KATSUYAMA ◽  
Makoto NAKAJIMA
Keyword(s):  
Bacterial Mutation

The use of tissues other than the liver for metabolic activation in bacterial mutation assays

1981 ◽  
Vol 85 (4) ◽  
pp. 269
Author(s):  
S.A. Hubbard ◽  
J. Knight ◽  
S. Moloney ◽  
D.J. Benford ◽  
J.W. Bridges
Keyword(s):  
Metabolic Activation ◽  
Bacterial Mutation

scholarly journals The evolution of bacterial mutation rates under simultaneous selection by interspecific and social parasitism

2013 ◽  
Vol 280 (1773) ◽  
pp. 20131913 ◽  
Author(s):  
Siobhán O'Brien ◽  
Antonio M. M. Rodrigues ◽  
Angus Buckling
Keyword(s):  
Mutation Rate ◽  
Social Parasitism ◽  
Mutation Rates ◽  
Bacterial Populations ◽  
Simultaneous Selection ◽  
Bacterial Mutation ◽  
Selection For ◽  
Intraspecific Parasitism ◽  
Theory And Experiments ◽  
Mutation Rate Evolution

Many bacterial populations harbour substantial numbers of hypermutable bacteria, in spite of hypermutation being associated with deleterious mutations. One reason for the persistence of hypermutators is the provision of novel mutations, enabling rapid adaptation to continually changing environments, for example coevolving virulent parasites. However, hypermutation also increases the rate at which intraspecific parasites (social cheats) are generated. Interspecific and intraspecific parasitism are therefore likely to impose conflicting selection pressure on mutation rate. Here, we combine theory and experiments to investigate how simultaneous selection from inter- and intraspecific parasitism affects the evolution of bacterial mutation rates in the plant-colonizing bacterium Pseudomonas fluorescens. Both our theoretical and experimental results suggest that phage presence increases and selection for public goods cooperation (the production of iron-scavenging siderophores) decreases selection for mutator bacteria. Moreover, phages imposed a much greater growth cost than social cheating, and when both selection pressures were imposed simultaneously, selection for cooperation did not affect mutation rate evolution. Given the ubiquity of infectious phages in the natural environment and clinical infections, our results suggest that phages are likely to be more important than social interactions in determining mutation rate evolution.

Anthracene-9,10-diones as Potential Anticancer Agents:  Bacterial Mutation Studies of Amido-Substituted Derivatives Reveal an Unexpected Lack of Mutagenicity

1998 ◽  
Vol 41 (19) ◽  
pp. 3748-3752 ◽  
Author(s):  
Stanley Venitt ◽  
Christopher Crofton-Sleigh ◽  
Mavis Agbandje ◽  
Terence C. Jenkins ◽  
Stephen Neidle
Keyword(s):  
Anticancer Agents ◽  
Bacterial Mutation

Coevolution with viruses drives the evolution of bacterial mutation rates

Nature ◽  
2007 ◽  
Vol 450 (7172) ◽  
pp. 1079-1081 ◽  
Author(s):  
Csaba Pal ◽  
María D. Maciá ◽  
Antonio Oliver ◽  
Ira Schachar ◽  
Angus Buckling
Keyword(s):  
Mutation Rates ◽  
Bacterial Mutation

Role of the Host Cell in Bacteriophage Morphogenesis: Effects of a Bacterial Mutation on T4 Head Assembly

1972 ◽  
Vol 239 (89) ◽  
pp. 38-41 ◽  
Author(s):  
C. P. GEORGOPOULOS ◽  
ROGER W. HENDRIX ◽  
A. D. KAISER ◽  
WILLIAM B. WOOD
Keyword(s):  
Host Cell ◽  
Head Assembly ◽  
Bacterial Mutation

Activity of 4CMB and 4HMB in bacterial mutation assays

1982 ◽  
Vol 100 (1-4) ◽  
pp. 33-34 ◽  
Author(s):  
D.C. Lodge ◽  
J. Bootman ◽  
K. May
Keyword(s):  
Bacterial Mutation
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