Faculty Opinions recommendation of Unusual complication after radiotherapy for breast cancer bronchiolitis obliterans organizing pneumonia case report and review of the literature.

Author(s):  
Gary Epler
2005 ◽  
Vol 91 (5) ◽  
pp. 421-423 ◽  
Author(s):  
Gabriella Guerriero ◽  
Cleonice Battista ◽  
Marilena Montesano ◽  
Rita Carino ◽  
Angelo Primavera ◽  
...  

Breast-conserving surgery and postoperative radiotherapy play an important role in the treatment of early breast cancer. Bronchiolitis obliterans with organizing pneumonia (BOOP) is an uncommon syndrome reported to be one of the complications of adjuvant radiotherapy. We report the case of a 71-year-old woman who developed cough, dyspnea and fever three weeks after radiation therapy to the left breast for breast carcinoma. Chest X-ray and computed tomography scan demonstrated alveolar opacities within both lungs. Antibiotic therapy against any probable septic pathology did not improve the symptoms, while corticosteroid treatment resulted in rapid clinical improvement together with regression of the pulmonary opacities. Irradiation was thought to be the cause of the migratory pneumonitis, hence this case was clinically diagnosed as radiation-induced migratory pneumonitis similar to BOOP, without lung biopsy. The present case suggests that one should be mindful of this disease when treating patients with a history of irradiation to the breast. BOOP promptly responds to systemic corticosteroid therapy with rapid improvement of symptoms and regression of the pulmonary opacities.


2008 ◽  
Vol 19 ◽  
pp. S19
Author(s):  
Pierluigi Pompili ◽  
Maria Luisa Colloca ◽  
Federico Grifalchi ◽  
Claudio Santini

CHEST Journal ◽  
2017 ◽  
Vol 152 (4) ◽  
pp. A596
Author(s):  
Demet Polat ◽  
Eylem Ozgur ◽  
Sibel Atis Nayci ◽  
Tuba Kara ◽  
Feramuz Apaydin ◽  
...  

2015 ◽  
Vol 101 (3) ◽  
pp. 0-0 ◽  
Author(s):  
Lorenzo Falcinelli ◽  
Rita Bellavita ◽  
Alberto Rebonato ◽  
Rita Chiari ◽  
Jacopo Vannucci ◽  
...  

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