Faculty Opinions recommendation of A preliminary study on the effects of exercising to maximum walking distance on platelet and endothelial function in patients with intermittent claudication.

2006 ◽  
Author(s):  
Lars Norgren
Keyword(s):  
Endothelial Function ◽  
Intermittent Claudication ◽  
Walking Distance ◽  
Preliminary Study

553 EFFECTS OF TREADMILL TRAINING ON WALKING DISTANCE AND ENDOTHELIAL FUNCTION IN PATIENTS WITH INTERMITTENT CLAUDICATION

2011 ◽  
Vol 12 (1) ◽  
pp. 117
Author(s):  
R.A. Januszek ◽  
P. Mika ◽  
A. Konik ◽  
R. Nowobilski ◽  
R. Niżankowski ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Intermittent Claudication ◽  
Treadmill Training ◽  
Walking Distance

Ventilatory threshold is related to walking tolerance in patients with intermittent claudication

VASA ◽  
2012 ◽  
Vol 41 (4) ◽  
pp. 275-281 ◽  
Author(s):  
da Rocha Chehuen ◽  
G. Cucato ◽  
P. dos Anjos Souza Barbosa ◽  
A. R. Costa ◽  
M. Ritti-Dias ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Uptake ◽  
Intermittent Claudication ◽  
Lower Limb ◽  
Ventilatory Threshold ◽  
Reactive Hyperemia ◽  
Ankle Brachial Index ◽  
Metabolic Parameters ◽  
Walking Distance ◽  
The Relationship

Background: This study assessed the relationship between lower limb hemodynamics and metabolic parameters with walking tolerance in patients with intermittent claudication (IC). Patients and methods: Resting ankle-brachial index (ABI), baseline blood flow (BF), BF response to reactive hyperemia (BFRH), oxygen uptake (VO2), initial claudication distance (ICD) and total walking distance (TWD) were measured in 28 IC patients. Pearson and Spearman correlations were calculated. Results: ABI, baseline BF and BF response to RH did not correlate with ICD or TWD. VO2 at first ventilatory threshold and VO2peak were significantly and positively correlated with ICD (r = 0.41 and 0.54, respectively) and TWD (r = 0.65 and 0.71, respectively). Conclusions: VO2peak and VO2 at first ventilatory threshold, but not ABI, baseline BF and BFHR were associated with walking tolerance in IC patients. These results suggest that VO2 at first ventilatory threshold may be useful to evaluate walking tolerance and improvements in IC patients.

Integrative therapy in patients with intermittent claudication

VASA ◽  
2015 ◽  
Vol 44 (2) ◽  
pp. 85-91
Author(s):  
Erich Minar
Keyword(s):  
Intermittent Claudication ◽  
Modern Technology ◽  
Walking Distance ◽  
Interventional Treatment ◽  
Therapeutic Concept ◽  
Integrative Therapy ◽  
Risk Factor Modification ◽  
Supervised Exercise ◽  
Main Challenge ◽  
Exercise Programmes

The generally accepted first-line treatment in patients with intermittent claudication is risk factor modification, medical treatment and exercise training. In an era of reduced resources, the benefit of any further invasive intervention must be weighted against best conservative therapy for patients with claudication. According to some recent trials an integrative therapeutic concept combining best conservative treatment - including (supervised) exercise therapy - with endovascular therapy gives the best midterm results concerning walking distance and health-related quality of life. The improved mid- and long-term patency rate with use of modern technology further supports this concept. The conservative and interventional treatment strategy are more complimentary than competitive. The current main challenge is to overcome the economic barriers concerning the availability of exercise programmes.

Mobile health technologies to improve walking distance in people with intermittent claudication

2021 ◽  
Vol 2021 (8) ◽  
Author(s):  
Marah Elfghi ◽  
Denise Dunne ◽  
Jennifer Jones ◽  
Irene Gibson ◽  
Gerard Flaherty ◽  
...  
Keyword(s):  
Intermittent Claudication ◽  
Mobile Health ◽  
Walking Distance ◽  
Health Technologies

Improvement of Walking Distance in Patients with Intermittent Claudication by Chronic Local Therapy with Isosorbide Dinitrate Ointment

Angiology ◽  
1988 ◽  
Vol 39 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Roberto Testa ◽  
Andrea Biagini ◽  
Claudio Michelassi ◽  
Michele Emdin ◽  
Maria Giovanna Mazzei ◽  
...  
Keyword(s):  
Intermittent Claudication ◽  
Isosorbide Dinitrate ◽  
Local Therapy ◽  
Walking Distance

Abstract 319: Effects of Muscle Stretching on Flow-Mediated Dilation of Popliteal Artery in Patients With Peripheral Artery Disease

2017 ◽  
Vol 37 (suppl_1) ◽  
Author(s):  
Kazuki Hotta ◽  
Wayne B Batchelor ◽  
James Graven ◽  
Vishal Dahya ◽  
Thomas E Noel ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Popliteal Artery ◽  
Calf Muscle ◽  
Walking Distance ◽  
Flow Mediated Dilation ◽  
Vascular Endothelial ◽  
Vascular Endothelial Function ◽  
Peripheral Artery ◽  
Muscle Stretching ◽  
Artery Disease

Patients with peripheral artery disease (PAD) frequently have walking impairment due to lower extremity claudication. Our preliminary results in a rat model of aging indicate that a program of daily calf muscle stretching improves endothelium-dependent dilation of soleus muscle arterioles and increases soleus muscle blood flow during exercise. However, the effects of muscle stretching on the function of arteries supplying the legs of PAD patients is unknown. We hypothesized that daily calf muscle stretching improves vascular endothelial function and walking distance in PAD patients. To test our hypothesis, a randomized, non-blinded, crossover study was performed. Four weeks of muscle stretching (30 min/d, 5 days/wk) and 4 weeks of sedentary lifestyle (no stretching) were performed in random order. Thirteen patients with PAD participated in this study (71 ± 2 years old; 7 males and 6 females). During the stretching intervention both ankle joints were maintained at 15o of dorsiflexion using ankle dorsiflexion splints to stretch their calf muscles at home. Flow-mediated dilation (FMD; dilation to post-occlusion reactive hyperemia) and nitroglycerin-induced dilation (dilation to sublingual 0.4 mg nitroglycerin) of the popliteal artery were measured after 4 weeks of muscle stretching and after the no stretching period using ultrasound. A six-minute walk test was also performed to obtain walking distance. After 4 weeks of muscle stretching, FMD and 6-minute walking distance significantly improved as compared to the values measured after 4 weeks of no stretching (FMD: 5.2 ± 0.6 % vs. 3.7 ± 0.4 %, P=0.003 stretching vs. no stretching, 6-minute walking distance: 355 ± 32 m vs. 311 ± 31 m, P=0.007, stretching vs. no stretching; mean ± SE). No difference in nitroglycerin-induced dilation was found between groups (10.9 ± 1.4 vs. 9.9 ± 1.1 %, P=0.54, stretching vs. no stretching). Percentage change of walking distance (%change = [(stretching - no stretching) / no stretching] x 100) significantly correlated with the %change of FMD (R 2 =0.65, P=0.03). These results indicate that static calf muscle stretching enhances vascular endothelial function of the popliteal artery, contributing to improvement of walking tolerance in PAD patients.

Change of walking distance in intermittent claudication: impact on inflammation, oxidative stress and mononuclear cells: a pilot study

2015 ◽  
Vol 104 (9) ◽  
pp. 751-763 ◽  
Author(s):  
Jörn F. Dopheide ◽  
Martin Scheer ◽  
Christopher Doppler ◽  
Viviane Obst ◽  
Pamela Stein ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Pilot Study ◽  
Intermittent Claudication ◽  
Mononuclear Cells ◽  
Walking Distance

Effect of Propionylcarnitine on Changes in Endothelial Function and Plasma Levels of Adhesion Molecules Induced by Acute Exercise in Patients with Intermittent Claudication

Angiology ◽  
2006 ◽  
Vol 57 (2) ◽  
pp. 145-154 ◽  
Author(s):  
Antonio Silvestro ◽  
Vittorio Schiano ◽  
Roxana Bucur ◽  
Gregorio Brevetti ◽  
Francesco Scopacasa ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Adhesion Molecules ◽  
Intermittent Claudication ◽  
Plasma Levels ◽  
Acute Exercise
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