Faculty Opinions recommendation of Impact of advanced age in lung transplantation: an analysis of United Network for Organ Sharing data.

2009 ◽  
Author(s):  
Paul Corris
Keyword(s):  
Lung Transplantation ◽  
Advanced Age ◽  
United Network

scholarly journals Feasibility of the Six-Minute Walk Test for Patients Who Have Cystic Fibrosis, Are Ambulatory, and Require Mechanical Ventilation Before Lung Transplantation

2016 ◽  
Vol 96 (9) ◽  
pp. 1468-1476 ◽  
Author(s):  
Amanda L. Malamud ◽  
Paul E.H. Ricard
Keyword(s):  
Cystic Fibrosis ◽  
Mechanical Ventilation ◽  
Lung Transplantation ◽  
Lung Transplant ◽  
Walk Test ◽  
Prolonged Intubation ◽  
Six Minute Walk Test ◽  
Medical Intensive Care ◽  
Minute Walk ◽  
United Network

Abstract Background and Purpose The Six-Minute Walk Test (6MWT) is a requirement for lung transplantation evaluation by the United Network for Organ Sharing. A subset of patients being evaluated for a lung transplantation require mechanical ventilation (MV) because of respiratory failure. The 6MWT has not been validated as an outcome measure for patients dependent on MV. Literature supports alternative forms of the 6MWT, including those with an oval track or treadmill, as valid for accommodating other populations. This case report describes the use of the 6MWT for 2 patients who had cystic fibrosis and required MV before a lung transplant. Case Description A 34-year-old woman and a 37-year-old woman were admitted to a medical intensive care unit for exacerbation of cystic fibrosis requiring prolonged intubation and a subsequent tracheostomy. Their hospital courses were characterized by participation in early rehabilitation and variable dependence on MV. Both patients performed the 6MWT for a lung transplantation workup while dependent on MV. Outcomes Both patients performed the 6MWT while using portable MV and achieved a distance greater than that required for transplantation consideration and approximately 50% of the reference-based expected distance for adults who are healthy. Confounding factors included external pacing and the use of an oval track. Discussion The use of the 6MWT for 2 patients receiving MV appeared to be feasible. Research regarding the validity of this outcome is warranted.

scholarly journals Impact of bilateral versus single lung transplantation on survival in recipients 60 years of age and older: Analysis of United Network for Organ Sharing database

2007 ◽  
Vol 133 (2) ◽  
pp. 541-547 ◽  
Author(s):  
Lois U. Nwakanma ◽  
Christopher E. Simpkins ◽  
Jason A. Williams ◽  
David C. Chang ◽  
Marvin C. Borja ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Single Lung Transplantation ◽  
United Network

scholarly journals Lessons learned from extracorporeal membrane oxygenation as a bridge to lung transplantation

2014 ◽  
Author(s):  
Vladimir Shumaster ◽  
Oliver Jawitz ◽  
David Yuh ◽  
Pramod Bonde
Keyword(s):  
Postoperative Complications ◽  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Survival Rates ◽  
Length Of Hospital Stay ◽  
Lessons Learned ◽  
Control Group ◽  
Membrane Oxygenation ◽  
Lung Transplants ◽  
United Network

Extracorporeal membrane oxygenation (ECMO) has been used infrequently as a bridge to lung transplantation due to lack of consensus and data regarding the benefits of such a strategy. We present data from the United Network of Organ Sharing (UNOS) database on the outcomes of patients bridged to lung transplantation with ECMO. We used the UNOS database to analyze data between January 1, 2000 and December 31, 2011. During this time 14,263 lung transplants were performed, of which 143 (1.0%) were bridged using ECMO. Patients on ECMO as a bridge to lung transplantation were compared to those transplanted without prior ECMO support. Demographics, survival rates, complications, and rejection episodes were compared between the two groups. The 30-day, 6-month, 1-year, 3-year, and 5-year survival rates were 69%, 56%, 48%, 26%, and 11%, respectively, for the ECMO bridge group and 95%, 88%, 81%, 58%, and 38% respectively, for the control group (p ≤ 0.01). The ECMO group incurred higher rate of postoperative complications, including airway dehiscence (4% vs. 1%, p ≤ 0.01), stroke (3% vs. 2%, p ≤ 0.01), infection (56% vs. 42%, p ≤ 0.01), and pulmonary embolism (10% vs. 0.6%, p ≤ 0.01). The length of hospital stay was longer for the ECMO group (41 vs. 25 days, p ≤ 0.01), and they were treated for rejection more often (49% vs. 36%, p = 0.02). The use of ECMO as a bridge to lung transplantation is associated with significantly worse survival and more frequent postoperative complications. Therefore, we advocate very careful patient selection and cautious use of ECMO.

Outcomes for Lung Transplantation for Lung Cancer in the United Network for Organ Sharing Registry

2012 ◽  
Vol 94 (3) ◽  
pp. 935-941 ◽  
Author(s):  
Usman Ahmad ◽  
Zuoheng Wang ◽  
Ayesha S. Bryant ◽  
Anthony W. Kim ◽  
Jasleen Kukreja ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lung Transplantation ◽  
United Network
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