Faculty Opinions recommendation of Topical application of honey in the management of radiation mucositis: a preliminary study.

2005 ◽  
Author(s):  
Carla Ripamonti
Keyword(s):  
Topical Application ◽  
Preliminary Study ◽  
Radiation Mucositis

Topical application of honey in the management of radiation mucositis. A Preliminary study

2003 ◽  
Vol 11 (4) ◽  
pp. 242-248 ◽  
Author(s):  
Biswa Mohan Biswal ◽  
Ahmad Zakaria ◽  
Nik Min Ahmad
Keyword(s):  
Topical Application ◽  
Preliminary Study ◽  
Radiation Mucositis

scholarly journals Preliminary study of therapeutic effect of parecoxib on severe radiation mucositis and dermatitis

2020 ◽  
Vol 4 ◽  
pp. 25-25
Author(s):  
Wei-Hsuan Huang ◽  
Shih-Hua Liu ◽  
Gwo-Che Huang ◽  
Che-Wei Su ◽  
Wan-Ju Lee ◽  
...  
Keyword(s):  
Therapeutic Effect ◽  
Preliminary Study ◽  
Radiation Mucositis

scholarly journals Topical application of adipose tissue-derived mesenchymal stem cells (ADMSCs) reduced cerebral edema in experimental traumatic brain injury (TBI)—a preliminary study

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Hui Ma ◽  
Lian Xu Cui ◽  
Ping Kuen Lam ◽  
Cindy S. W. Tong ◽  
Kin K. Y. Lo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Brain Injury ◽  
Topical Application ◽  
Cerebral Edema ◽  
Therapeutic Effects ◽  
Edema Formation ◽  
Hypoxic Precondition ◽  
Preliminary Study

Abstract Background Our previous studies showed that topical application of mesenchymal stem cells (MSCs) improved functional recovery in rat traumatic brain injury (TBI) model, and hypoxic precondition further enhanced the therapeutic effects of MSCs. There was no previous study on the attenuation of cerebral edema by MSCs. We investigated whether topical application of normoxic and hypoxic MSCs could reduce cerebral edema in an experimental TBI model. Methods Two million normoxic (N = 24) and hypoxic (N = 24) MSCs were applied topically to exposed the cerebral cortex in a controlled cortical impact (CCI) model. The MSCs were fixed in position with fibrin glue. No treatment was given to control animals (TBI only: n = 24). After surgery, four animals in each group were sacrificed daily (day 1 to day 6) for edema evaluation. Normal animals without TBI were used as reference (n = 4). The expressions of GFAP, AQP4, and MMP9 were also investigated by immunofluorescence staining and RT-PCR at day 3. Results The edema peaked within 3 days after TBI. Compared with the control, hypoxic MSCs reduced brain water content significantly (p < 0.05). Both hypoxic and normoxic MSCs downregulated the expression of MMP9 and normalized AQP4 distribution to astrocyte end feet. Conclusion Our preliminary study showed that topical application of hypoxic MSCs suppressed both vasogenic and cytotoxic edema formation.

scholarly journals Topical application of adipose tissue derived mesenchymal stem cells (ADMSCs) reduced cerebral edema in experimental traumatic brain injury (TBI)- a preliminary study

2020 ◽  
Author(s):  
Hui MA ◽  
Lian Xu Cui ◽  
Ping Kuen Lam ◽  
Cindy SW Tong ◽  
Kin KY Lo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Brain Injury ◽  
Topical Application ◽  
Cerebral Edema ◽  
Therapeutic Effects ◽  
Edema Formation ◽  
Hypoxic Precondition ◽  
Preliminary Study

Abstract Background: Our previous studies showed that topical application of mesenchymal stem cells (MSCs) improved functional recovery in rat traumatic brain injury (TBI) model, and hypoxic precondition further enhanced the therapeutic effects of MSCs. There was no previous study on the attenuation of cerebral edema by MSCs. Objective: We investigated whether topical application of normoxic and hypoxic MSCs could reduce cerebral edema in an experimental TBI model. Methods: 2 million normoxic (N=24) and hypoxic (N=24) MSCs were applied topically to exposed cerebral cortex in a controlled cortical impact (CCI) model. The MSCs were fixed in position with fibrin glue. No treatment was given to control animals (TBI only: n=24). After surgery, four animals in each group were sacrificed daily (day 1 to day 6) for edema evaluation. Normal animals without TBI were used as reference (n=4). The expressions of GFAP, AQP4 and MMP9 were also investigated by immunofluorescence staining and RT-PCR at day 3. Results: The edema peaked within 3 days after TBI. Compared with the control, hypoxic MSCs reduced brain water content significantly (p<0.05). Both hypoxic and normoxic MSCs downregulated the expression of MMP9 and normalized AQP4 distribution to astrocytes end feet. Conclusion: Our preliminary study showed that topical application of hypoxic MSCs suppressed both vasogenic and cytotoxic edema formation.

scholarly journals Topical application of adipose tissue derived mesenchymal stem cells (ADMSCs) reduced cerebral edema in experimental traumatic brain injury (TBI)- a preliminary study

2020 ◽  
Author(s):  
Hui MA ◽  
Lian Xu Cui ◽  
Ping Kuen Lam ◽  
Cindy SW Tong ◽  
Kin KY Lo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Brain Injury ◽  
Topical Application ◽  
Cerebral Edema ◽  
Therapeutic Effects ◽  
Edema Formation ◽  
Hypoxic Precondition ◽  
Preliminary Study

Abstract Background: Our previous studies showed that topical application of mesenchymal stem cells (MSCs) improved functional recovery in rat traumatic brain injury (TBI) model, and hypoxic precondition further enhanced the therapeutic effects of MSCs. There was no previous study on the attenuation of cerebral edema by MSCs. Objective: We investigated whether topical application of normoxic and hypoxic MSCs could reduce cerebral edema in an experimental TBI model. Methods: 2 million normoxic (N=24) and hypoxic (N=24) MSCs were applied topically to exposed cerebral cortex in a controlled cortical impact (CCI) model. The MSCs were fixed in position with fibrin glue. No treatment was given to control animals (TBI only: n=24). After surgery, four animals in each group were sacrificed daily (day 1 to day 6) for edema evaluation. Normal animals without TBI were used as reference (n=4). The expressions of GFAP, AQP4 and MMP9 were also investigated by immunofluorescence staining and RT-PCR at day 3. Results: The edema peaked within 3 days after TBI. Compared with the control, hypoxic MSCs reduced brain water content significantly (p<0.05). Both hypoxic and normoxic MSCs downregulated the expression of MMP9 and normalized AQP4 distribution to astrocytes end feet. Conclusion: Our preliminary study showed that topical application of hypoxic MSCs suppressed both vasogenic and cytotoxic edema formation. Keywords: topical, MSCs, cerebral edema, TBI

Efficacy of garlic paste in oral candidiasis

2005 ◽  
Vol 35 (2) ◽  
pp. 99-99
Author(s):  
P Sabitha ◽  
Prabha M Adhikari ◽  
Shalini M Shenoy ◽  
Asha Kamath ◽  
Rampuram John ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Topical Application ◽  
Oral Candidiasis ◽  
Clinical Signs ◽  
Preliminary Study

In a randomized trial of 56 patients, topical application of garlic paste for 14 days was found to be as effective as that of clotrimazole solution in suppressing clinical signs of oral candidiasis. The results of this preliminary study explore the possible role of garlic paste in the treatment of oral candidiasis.

scholarly journals In vitro preliminary study of osteoblast response to surface roughness of titanium discs and topical application of melatonin

2015 ◽  
pp. e88-e93 ◽  
Author(s):  
MF. Sola-Ruiz ◽  
C. Perez-Martinez ◽  
JJ. Martin-del-Llano ◽  
C. Carda-Batalla ◽  
C. Labaig-Rueda
Keyword(s):  
Surface Roughness ◽  
Topical Application ◽  
Preliminary Study
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