scholarly journals Faculty Opinions recommendation of A randomized clinical trial of peak flow versus symptom monitoring in older adults with asthma.

2007 ◽  
Author(s):  
Martyn R Partridge
Keyword(s):  
Older Adults ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Peak Flow ◽  
Symptom Monitoring

scholarly journals A Randomized Clinical Trial of Peak Flow versus Symptom Monitoring in Older Adults with Asthma

2006 ◽  
Vol 174 (10) ◽  
pp. 1077-1087 ◽  
Author(s):  
A. Sonia Buist ◽  
William M. Vollmer ◽  
Sandra R. Wilson ◽  
E. Ann Frazier ◽  
Arthur D. Hayward
Keyword(s):  
Older Adults ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Peak Flow ◽  
Symptom Monitoring

scholarly journals Effect of Aerobic Exercise Training and Essential Amino Acid Supplementation for 24 Weeks on Physical Function, Body Composition, and Muscle Metabolism in Healthy, Independent Older Adults: A Randomized Clinical Trial

2018 ◽  
Vol 74 (10) ◽  
pp. 1598-1604 ◽  
Author(s):  
Melissa M Markofski ◽  
Kristofer Jennings ◽  
Kyle L Timmerman ◽  
Jared M Dickinson ◽  
Christopher S Fry ◽  
...  
Keyword(s):  
Older Adults ◽  
Clinical Trial ◽  
Body Composition ◽  
Protein Synthesis ◽  
Muscle Strength ◽  
Randomized Clinical Trial ◽  
Walking Speed ◽  
Muscle Protein ◽  
Muscle Protein Synthesis ◽  
Before And After

Abstract Background Essential amino acids (EAA) and aerobic exercise (AE) acutely and independently stimulate skeletal muscle protein anabolism in older adults. Objective In this Phase 1, double-blind, placebo-controlled, randomized clinical trial, we determined if chronic EAA supplementation, AE training, or a combination of the two interventions could improve muscle mass and function by stimulating muscle protein synthesis. Methods We phone-screened 971, enrolled 109, and randomized 50 independent, low-active, nonfrail, and nondiabetic older adults (age 72 ± 1 years). We used a 2 × 2 factorial design. The interventions were: daily nutritional supplementation (15 g EAA or placebo) and physical activity (supervised AE training 3 days/week or monitored habitual activity) for 24 weeks. Muscle strength, physical function, body composition, and muscle protein synthesis were measured before and after the 24-week intervention. Results Forty-five subjects completed the 24-week intervention. VO2peak and walking speed increased (p < .05) in both AE groups, irrespective of supplementation type, but muscle strength increased only in the EAA + AE group (p < .05). EAA supplementation acutely increased (p < .05) muscle protein synthesis from basal both before and after the intervention, with a larger increase in the EAA + AE group after the intervention. Total and regional lean body mass did not change significantly with any intervention. Conclusions In nonfrail, independent, healthy older adults AE training increased walking speed and aerobic fitness, and, when combined with EAA supplementation, it also increased muscle strength and EAA-stimulated muscle protein synthesis. These increases occurred without improvements in muscle mass.

scholarly journals The Impact of Levothyroxine on Cardiac Function in Older Adults With Mild Subclinical Hypothyroidism: A Randomized Clinical Trial

2020 ◽  
Vol 133 (7) ◽  
pp. 848-856.e5 ◽  
Author(s):  
Baris Gencer ◽  
Elisavet Moutzouri ◽  
Manuel R. Blum ◽  
Martin Feller ◽  
Tinh-Hai Collet ◽  
...  
Keyword(s):  
Older Adults ◽  
Clinical Trial ◽  
Cardiac Function ◽  
Randomized Clinical Trial ◽  
Subclinical Hypothyroidism ◽  
The Impact

scholarly journals Keys to staying sharp: A randomized clinical trial of piano training among older adults with and without mild cognitive impairment

2019 ◽  
Vol 84 ◽  
pp. 105789 ◽  
Author(s):  
Elizabeth M. Hudak ◽  
Jennifer Bugos ◽  
Ross Andel ◽  
Jennifer J. Lister ◽  
Ming Ji ◽  
...  
Keyword(s):  
Older Adults ◽  
Clinical Trial ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Randomized Clinical Trial

scholarly journals Effects of short term elastic resistance training on muscle mass and strength in untrained older adults: a randomized clinical trial

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Wagner Rodrigues Martins ◽  
Marisete Peralta Safons ◽  
Martim Bottaro ◽  
Juscelino Castro Blasczyk ◽  
Leonardo Rios Diniz ◽  
...  
Keyword(s):  
Older Adults ◽  
Clinical Trial ◽  
Resistance Training ◽  
Randomized Clinical Trial ◽  
Muscle Mass ◽  
Short Term ◽  
Elastic Resistance
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