scholarly journals Incidence of Urinary Tract Infections among Adolescent and Adult Women

2019 ◽  
pp. 34-41
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Age Groups ◽  
Personal Hygiene ◽  
P Value ◽  
Adult Women ◽  
Adolescent Women ◽  
Tract Infections

This study was to determine the bacteria that are prevalent in Urinary tract infections and the sensitivity of organisms isolated from the urine of adolescent and adult women of 8- 52 years old in Ogbete Coal camp in Enugu metropolis, south east Nigeria. A total of 218 individuals, both in and out patients were investigated, 197 (90.3%) women were diagnosed for Urinary tract infections. Therefore, incidence of UTI were prevalent in the age groups of 13-17 and 18-22, with P value (p=0.047 and S.D of ± 5.6). The microorganisms implicated in infection were bacteria, fungi, yeast and protozoa. Among the bacteria, two were identified as Gram positive cocci i.e. Staphylococcus aureus and Staphylococcus saprophyticus, while Gram negative bacilli were Escherichia coli, Klebsiella, Proteus, Pseudomonas areuginosa. Yeast like fungus Candida albican, protozoan (Trichomonasvaginalis) was also identified. The isolated organism which was prevalent was Staphylococcus aureus (48.2%); followed by Escherichia coli (34.5%). Also, Pseudomonas aureuginosa, Proteus and Klebsiella were isolated. Factors responsible for frequent cases of Urinary tract infections among diagnosed women include shortness of urethra among the females, lack of personal hygiene, sexual intercourse, socio economic challenges in various homes and others. Sensitivity profiles revealed that Augumentin was highly susceptible to Staphylococcus aureus (65%) while Escherichia coli were highly resistant to commonly used drugs such as Ampicillin, and Cloxacillin while Gentamycin was the most active against bacteria isolates. Keywords: Urinary Tract Infection, Adolescent Women, Antimicrobial Sensitivity, Staphylococcus aureus, Escherichia coli

scholarly journals Urinary Excretion and Bactericidal Activities of Gemifloxacin and Ofloxacin after a Single Oral Dose in Healthy Volunteers

2001 ◽  
Vol 45 (12) ◽  
pp. 3524-3530 ◽  
Author(s):  
Christoph K. Naber ◽  
Michaela Hammer ◽  
Martina Kinzig-Schippers ◽  
Christian Sauber ◽  
Fritz Sörgel ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Urinary Tract ◽  
Urinary Excretion ◽  
Enterococcus Faecalis ◽  
Urinary Tract Infections ◽  
Parent Drug ◽  
Oral Dosage ◽  
Tract Infections ◽  
Cumulative Excretion

ABSTRACT In a randomized crossover study, 16 volunteers (8 men, 8 women) received single oral doses of 320 mg of gemifloxacin and 400 mg of ofloxacin on two separate occasions in the fasting state to assess the urinary excretion and urinary bactericidal titers (UBTs) at intervals for up to 144 h. Ofloxacin showed higher concentrations in urine compared with those of gemifloxacin. The median (range) cumulative excretion of gemifloxacin was 29.7% (8.4 to 48.7%) of the parent drug administered, and median (range) cumulative excretion of ofloxacin was 84.3% (46.5 to 95.2%) of the parent drug administered. The UBTs, i.e., the highest twofold dilutions (with antibiotic-free urine as the diluent) of urine that were still bactericidal, were determined for a reference strain and nine uropathogens for which the MICs of gemifloxacin and ofloxacin were as follows:Escherichia coli ATCC 25922, 0.016 and 0.06 μg/ml, respectively; Klebsiella pneumoniae, 0.03 and 0.06 μg/ml, respectively; Proteus mirabilis, 0.125 and 0.125 μg/ml, respectively; Escherichia coli, 0.06 and 0.5 μg/ml, respectively; Pseudomonas aeruginosa, 1 and 4 μg/ml, respectively; Staphylococcus aureus, 0.008 and 0.25 μg/ml, respectively; Enterococcus faecalis, 0.06 and 2 μg/ml, respectively;Staphylococcus aureus, 0.25 and 4 μg/ml, respectively;Enterococcus faecalis, 0.5 and 32 μg/ml, respectively; and Staphylococcus aureus, 2 and 32 μg/ml, respectively. Generally, the UBTs for gram-positive uropathogens were higher for gemifloxacin than for ofloxacin and the UBTs for gram-negative uropathogens were higher for ofloxacin than for gemifloxacin. According to the UBTs, ofloxacin-resistant uropathogens (MICs, ≥4 mg/liter) should also be considered gemifloxacin resistant. Although clinical trials have shown that gemifloxacin is effective for the treatment of uncomplicated urinary tract infections, whether an oral dosage of 320 mg of gemifloxacin once daily is also adequate for the treatment of complicated urinary tract infections has yet to be confirmed.

scholarly journals Role of Urinary Cathelicidin LL-37 and Human β-Defensin 1 in Uncomplicated Escherichia coli Urinary Tract Infections

2014 ◽  
Vol 82 (4) ◽  
pp. 1572-1578 ◽  
Author(s):  
Karen L. Nielsen ◽  
Pia Dynesen ◽  
Preben Larsen ◽  
Lotte Jakobsen ◽  
Paal S. Andersen ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Adult Women ◽  
Content Type ◽  
E Coli ◽  
Innate Defense ◽  
High Level ◽  
Tract Infections

ABSTRACTCathelicidin (LL-37) and human β-defensin 1 (hBD-1) are important components of the innate defense in the urinary tract. The aim of this study was to characterize whether these peptides are important for developing uncomplicatedEscherichia coliurinary tract infections (UTIs). This was investigated by comparing urinary peptide levels of UTI patients during and after infection to those of controls, as well as characterizing the fecal flora of participants with respect to susceptibility to LL-37 andin vivovirulence. Forty-seven UTI patients and 50 controls who had never had a UTI were included. Participants were otherwise healthy, premenopausal, adult women. LL-37 MIC levels were compared for fecalE. coliclones from patients and controls and were also compared based on phylotypes (A, B1, B2, and D).In vivovirulence was investigated in the murine UTI model by use of selected fecal isolates from patients and controls. On average, UTI patients had significantly more LL-37 in urine during infection than postinfection, and patient LL-37 levels postinfection were significantly lower than those of controls. hBD-1 showed similar urine levels for UTI patients and controls. FecalE. coliisolates from controls had higher LL-37 susceptibility than fecal and UTIE. coliisolates from UTI patients.In vivostudies showed a high level of virulence of fecalE. coliisolates from both patients and controls and showed no difference in virulence correlated with the LL-37 MIC level. The results indicate that the concentration of LL-37 in the urinary tract and low susceptibility to LL-37 may increase the likelihood of UTI in a complex interplay between host and pathogen attributes.

Quantitative and bacteriological studies of urine specimens from canine and feline urinary tract infections

1976 ◽  
Vol 4 (4) ◽  
pp. 326-329
Author(s):  
R E Wooley ◽  
J L Blue
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Antibacterial Agents ◽  
Clinical Signs ◽  
Tract Infections ◽  
And Staphylococcus Aureus ◽  
Urine Specimens

The most prevalent microorganisms isolated from urine specimens of dogs (385) and cats (132) with clinical signs of urinary tract infections were Escherichia coli, Proteus spp., and Staphylococcus aureus. The results of quantitative urine-culturing methods showed 48.6% of the canine and 12.1% of the feline specimens had more than 10(5) organisms per ml of urine. The bacteria isolated appear to have a greater resistance to antibacterial agents than previously reported.

scholarly journals ASSOCIATION BETWEEN AGE, BODY MASS INDEX, WAIST CIRCUMFERENCE, LIPID PROFILE PARAMETERS, AND SYMPTOMATIC BACTERIAL URINARY TRACT INFECTION IN IRAQI ADULT WOMEN

2016 ◽  
Vol 9 (9) ◽  
pp. 57
Author(s):  
Sundus Fadhil Hantoosh ◽  
Haider K Al-rubai ◽  
Dheaa Sh Zageer ◽  
Ibtisam Hammood Naser Al-musawi
Keyword(s):  
Body Mass Index ◽  
Urinary Tract ◽  
Waist Circumference ◽  
Lipid Profile ◽  
Body Mass ◽  
Urinary Tract Infections ◽  
Age Groups ◽  
Control Group ◽  
Adult Women ◽  
Tract Infections

ABSTRACTObjective: This study was conducted to investigate the association between age, body mass index (BMI), waist circumference (WC), and incidence ofsymptomatic bacterial urinary tract infections in adult women and to study the impact of infection on lipid profile.Methods: A total of 30 women enrolled with symptomatic bacterial urinary tract infections and 10 healthy women as control group. Mid-stream urinesamples were submitted. BMI, WC, and lipid profile were measured. Both leukocyte esterase and nitrite tests were used to diagnose the urinary tractinfection, and viable quantification was done as confirmatory for the diagnosis.Results: Revealed that there was a significant relationship between the incidence of symptomatic bacterial urinary tract infections and age groups(p=0.04) as age group (21-30) years recorded the highest percentage (33.33%) followed by the age group (31-40) which recorded 30%. No significantassociation was found between BMI, WC and incidence of symptomatic bacterial urinary tract infections (p=0.08, p=0.14) respectively. Comparedto healthy control group, there was a significant decrease in the levels of total cholesterol, triglycerides, high-density-lipoprotein, very-low-densitylipoprotein,and low-density-lipoprotein (p=0.0001, p=0.006, p=0.001, p=0.006, and p=0.0001), respectively.Conclusion: The young women were significantly susceptible to symptomatic bacterial urinary tract infections than other age groups. Both BMI andWC were not significant indicators for the incidence of symptomatic bacterial urinary tract infections in adult women. Adult women with symptomaticbacterial urinary tract infections showed a significant decrease in lipid profile parameters when compared with the control healthy adult women.Keywords: Age, Body mass index, Waist circumference, Lipid profile, Urinary tract infections.

scholarly journals Waterborne Urinary Tract Infections: Have We Overlooked an Important Source of Exposure?

2021 ◽  
Author(s):  
Jay P. Graham ◽  
Heather Amato ◽  
Renata Mendizabal-Cabrera ◽  
Danilo Alvarez ◽  
Brooke Ramay
Keyword(s):  
Escherichia Coli ◽  
Drinking Water ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Scientific Literature ◽  
Adult Women ◽  
Water Supplies ◽  
E Coli ◽  
Tract Infections

The presence of intestinal pathogenic Escherichia coli in drinking water is well recognized as a risk for diarrhea. The role of drinking water in extraintestinal infections caused by E. coli—such as urinary tract infections (UTIs)—remains poorly understood. Urinary tract infections are a leading cause of outpatient infections globally, with a lifetime incidence of 50–60% in adult women. We reviewed the scientific literature on the occurrence of uropathogenic E. coli (UPEC) in water supplies to determine whether the waterborne route may be an important, overlooked, source of UPEC. A limited number of studies have assessed whether UPEC isolates are present in drinking water supplies, but no studies have measured whether their presence in water may increase UPEC colonization or the risk of UTIs in humans. Given the prevalence of drinking water supplies contaminated with E. coli across the globe, efforts should be made to characterize UTI-related risks associated with drinking water, as well as other pathways of exposure.

Molecular Analysis of Uropathogenic E.coli Isolates from Urinary Tract Infections

2019 ◽  
Vol 19 (3) ◽  
pp. 322-326 ◽  
Author(s):  
Hassan Valadbeigi ◽  
Elham Esmaeeli ◽  
Sobhan Ghafourian ◽  
Abbas Maleki ◽  
Nourkhoda Sadeghifard
Keyword(s):  
Escherichia Coli ◽  
Polymerase Chain Reaction ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Multiplex Polymerase Chain Reaction ◽  
Virulence Genes ◽  
Uropathogenic Escherichia Coli ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Tract Infections

Introduction: The aim of the current study was to investigate the prevalence of virulence genes in uropathogenic Escherichia coli (UPEC) isolates in Ilam. Materials and Methods: For this purpose, a total of 80 UPEC isolates were collected for patients with UTIs during a 6 months period. The multiplex polymerase chain reaction (multiplex PCR) was used to detect the papEF, fimH, iucD, hlyA, fyuA, and ompT genes. Results: The prevalence of fimH, papEF, iucD, fyuA, hlyA, hlyA, and ompT genes were 87.5%, 47.5%, 60%, 67.5%, 27.5%, 47.5% and 71.2%, respectively. Among all of the isolates, 27 profiles were obtained. Conclusion: Our findings demonstrated that the most prevalence was found for fimH, and different distribution of virulence genes suggested different ability of pathogenicity.

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