scholarly journals Validation study of Bekaert's age estimation model based on DNA methylation rate and development of novel models using Japanese blood samples

2021 ◽  
Author(s):  
Yuya Hamano ◽  
Ken Watanabe ◽  
Kochi Toyomane ◽  
Chie Morimoto ◽  
Keiji Tamaki ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Validation Study ◽  
Age Estimation ◽  
Estimation Model ◽  
Blood Samples ◽  
Methylation Rate ◽  
Model Based

Age Estimation Based on DNA Methylation Using Blood Samples From Deceased Individuals

2019 ◽  
Vol 65 (2) ◽  
pp. 465-470 ◽  
Author(s):  
Helena Correia Dias ◽  
Cristina Cordeiro ◽  
Francisco Corte Real ◽  
Eugénia Cunha ◽  
Licínio Manco
Keyword(s):  
Dna Methylation ◽  
Age Estimation ◽  
Blood Samples

DNA methylation age estimation in blood samples of living and deceased individuals using a multiplex SNaPshot assay

2020 ◽  
Vol 311 ◽  
pp. 110267 ◽  
Author(s):  
Helena Correia Dias ◽  
Cristina Cordeiro ◽  
Janet Pereira ◽  
Catarina Pinto ◽  
Francisco Corte Real ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Age Estimation ◽  
Blood Samples ◽  
Dna Methylation Age

Age estimation by DNA methylation levels in Iraqi subjects

Gene Reports ◽  
2021 ◽  
Vol 23 ◽  
pp. 101022
Author(s):  
Hiba S.G. Al-Ghanmy ◽  
Nihad A.M. Al-Rashedi ◽  
Asaad Y. Ayied
Keyword(s):  
Dna Methylation ◽  
Age Estimation

scholarly journals Multi-species and multi-tissue methylation clocks for age estimation in toothed whales and dolphins

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Todd R. Robeck ◽  
Zhe Fei ◽  
Ake T. Lu ◽  
Amin Haghani ◽  
Eve Jourdain ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Age Estimation ◽  
Species Conservation ◽  
Genome Wide ◽  
Epigenetic Aging ◽  
Highly Correlated ◽  
Methylation Patterns ◽  
Cg Dinucleotides ◽  
Free Ranging ◽  
Unique Species

AbstractThe development of a precise blood or skin tissue DNA Epigenetic Aging Clock for Odontocete (OEAC) would solve current age estimation inaccuracies for wild odontocetes. Therefore, we determined genome-wide DNA methylation profiles using a custom array (HorvathMammalMethyl40) across skin and blood samples (n = 446) from known age animals representing nine odontocete species within 4 phylogenetic families to identify age associated CG dinucleotides (CpGs). The top CpGs were used to create a cross-validated OEAC clock which was highly correlated for individuals (r = 0.94) and for unique species (median r = 0.93). Finally, we applied the OEAC for estimating the age and sex of 22 wild Norwegian killer whales. DNA methylation patterns of age associated CpGs are highly conserved across odontocetes. These similarities allowed us to develop an odontocete epigenetic aging clock (OEAC) which can be used for species conservation efforts by provide a mechanism for estimating the age of free ranging odontocetes from either blood or skin samples.

scholarly journals Author Correction: Artificial neural network, predictor variables and sensitivity threshold for DNA methylation-based age prediction using blood samples

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zhonghui Thong ◽  
Jolena Ying Ying Tan ◽  
Eileen Shuzhen Loo ◽  
Yu Wei Phua ◽  
Xavier Liang Shun Chan ◽  
...  
Keyword(s):  
Neural Network ◽  
Dna Methylation ◽  
Artificial Neural Network ◽  
Predictor Variables ◽  
Sensitivity Threshold ◽  
Blood Samples ◽  
Artificial Neural ◽  
Age Prediction

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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