scholarly journals Determination of hydrogen sulfide in whole blood by headspace-gas chromatography/mass spectrometry

2020 ◽  
Vol 25 (2) ◽  
pp. 151-158
Author(s):  
Yoshiaki Iwamuro ◽  
Takaya Murakami ◽  
Reiko Ishimaru ◽  
Yuki Sakamoto ◽  
Satoshi Chinaka
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Hydrogen Sulfide ◽  
Whole Blood ◽  
Gas Chromatography Mass Spectrometry ◽  
Headspace Gas Chromatography ◽  
Chromatography Mass Spectrometry ◽  
Headspace Gas

scholarly journals Simultaneous Determination of Four Aldehydes in Gas Phase of Mainstream Smoke by Headspace Gas Chromatography-Mass Spectrometry

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Xiaotao Zhang ◽  
Ruoning Wang ◽  
Li Zhang ◽  
Jianke Wei ◽  
Yibin Ruan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Gas Phase ◽  
Gas Chromatography Mass Spectrometry ◽  
Headspace Gas Chromatography ◽  
Mainstream Smoke ◽  
Chromatography Mass Spectrometry ◽  
Headspace Gas ◽  
Cigarette Mainstream Smoke

A method for simultaneous determination of acetaldehyde, propionaldehyde, acrolein, and crotonaldehyde in gas phase of cigarette mainstream smoke by headspace gas chromatography-mass spectrometry was developed and validated. Gas phase components of mainstream cigarette smoke were extracted with methanol, and then the samples were separated on a DB 624 (60 m, 0.32 mm x 1.8 mm) column, analyzed with headspace gas chromatography-mass spectrometry, and quantified by isotope internal standard. The linearities of acetaldehyde, propionaldehyde, acrolein, and crotonaldehyde were good (R2>0.992). The recoveries of acetaldehyde, propionaldehyde, acrolein, and crotonaldehyde were between 78.5% and 115%. The relative standard deviations were less than 10%. The limits of detection and limits of quantitation were 0.014 μg/cigarette ~0.12 μg/cigarette and 0.045 μg/cigarette ~0.38 μg/cigarette, respectively. The method had advantage of high sensitivity, it did not require derivatization of 2,4-dinitrophenylhydrazine and avoided a large number of adverse reactions during the process of derivation to improve the accuracy of result, and it was suitable for quantitative analysis of four aldehydes in gas phase of cigarette mainstream smoke.

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