STUDY ON PRE-HYPERTENSION PREVALENCE AND RELATIONSHIP WITH DYSLIPIDEMIA IN ADULTS AT QUANG NAM PROVINCE

2019 ◽  
pp. 51-57
Author(s):  
Muoi To ◽  
Khanh Hoang ◽  
Van Minh Huynh

Objectives: To investigate the prevalence, risk factors of prehypertension in QuangNam province of Vietnam. Methods: A case-control study of 3.237 adults (aged ≥ 25 years) was conducted in Quang Nam province, Vietnam in 2017, using questionnaire interviews, clinical examinations, and laboratory tests. Blood pressure, anthropometry, plasma glucose and lipids were measured. The variables contributing significantly to pre-hypertension were analyzed by multiple logistic regression analysis. Results: The prevalence of prehypertension, hypertension and normal blood pressure was 30.7%, 31.6% and 37.7%, respectively. Cardiovascular risk factors such as overweight and obesity, family history of hypertension, alcohol abuse, smoking, diabetes, high total cholesterol levels, high triglyceride levels, high LDL-C levels were significantly greater in prehypertensive compared to optimal blood pressure (BP). Multivariable logistic regression analysis revealed strong positive associations of pre-hypertension with alcohol abuse (OR = 1.68; CI 95%: 1.29-2.20; p < 0.001), diabetes (OR = 3.39; CI 95%: 1.32 - 8.65; p=0.011); high triglyceride levels (OR = 1.41, CI 95%: 1.13 - 1.75, p = 0.002); high LDL-C levels (OR = 1.42; CI 95%: 1.03 - 1.97; p=0.034). There was a positive correlation of cardiovascular risk factors such as BMI, abdominal circumference, blood glucose, blood cholesterol, blood triglyceride, blood LDL-C with changes in systolic BP, diastolic BP, and average BP. Conclusions: The prevalence of prehypertension in Quang Nam province of Vietnam was 30.7%. Risk factors such as alcohol abuse, diabetes, high triglycerides, high LDL-C were significantly associated with prehypertension. Key words: cardiovascular risk factors - hypertension – prehypertension

2019 ◽  
pp. 71-77
Author(s):  
Muoi To ◽  
Khanh Hoang ◽  
Van Minh Huynh

Objectives: To investigate the prevalence, risk factors of prehypertension in QuangNam province of Vietnam. Methods: A case-control study of 3,237 adults (aged ≥ 25 years) was conducted in Quang Nam province, Vietnam in 2017, using questionnaire interviews, clinical examinations, and laboratory tests. Blood pressure, anthropometry, plasma glucose and lipids were measured. The variables contributing significantly to pre-hypertension were analyzed by multiple logistic regression analysis. Results: The prevalence of prehypertension was 30.7%, hypertension 31.6% and normal blood pressure was 37.7%. Lipid disorders such as high total cholesterol levels, high triglyceride levels, high LDL-C levels were significantly higher in prehypertensive than optimal blood pressure (BP). Multivariable logistic regression analysis revealed strong positive associations of pre-hypertension with high triglyceride levels (OR = 1.41, CI 95%: 1.13 - 1.75, p = 0.002); high LDL-C levels (OR = 1.42; CI 95%: 1.03 - 1.97; p = 0,034). The area under the ROC curve of triglyceride, cholesterol, LDL-C was 0.578; 0.566; 0.549, respectively. There was a positive correlation of blood cholesterol, blood triglyceride, blood LDL-C with changes in systolic BP, diastolic BP, and average BP. Conclusions: The prevalence of prehypertension in Quang Nam province of Vietnam was 30.7%. High cholesterol, high triglycerides, high LDL-C level were significantly associated with prehypertension. Key words: Lipid – prehypertension


2018 ◽  
Vol 3 (3) ◽  
pp. 134-140
Author(s):  
Victoria Ancuța Rus ◽  
Florina Ruța ◽  
Maria Sălcudean ◽  
Monica Tarcea ◽  
Costela Șerban ◽  
...  

Abstract Background: Adopting a healthy lifestyle, including a healthy diet, weight control, regular exercise, smoking cessation, and alcohol limitation, plays an important role in treating high blood pressure and cardiovascular and chronic diseases. Aim: This study aimed to investigate adherence to the DASH diet in relation to the occurrence of high blood pressure and chronic disease risk factors, in a group of people from Tîrgu Mureș. Material and methods: This was a cross-sectional study based on a food frequency and lifestyle questionnaire applied to a group of 2,010 people aged 15–92 years from Tîrgu Mureș. Results: Individuals over the age of 45 had higher DASH scores (Q4, Q5) compared to subjects younger than 40 years (Q1 and Q2, p <0.001). An important percentage (19.3%) of subjects who preferred a meat-based diet (Q3) had significantly larger abdominal circumference (mean 92.2 ± 0.91 cm, p <0.001). An association between pure alcohol intake (mean 5.6 ± 0.43 g) and an unhealthy diet (Q1) was observed, compared to the average 1.7 ± 19 g of alcohol consumed by subjects with a healthy diet (Q5), alcohol consumption decreasing with an increasing DASH score (p <0.001). Conclusion: This study shows that individuals diagnosed with at least one cardiovascular risk factor had a higher adherence to the DASH diet than individuals with no cardiovascular risk factors, most likely due to the fact that diagnosed individuals had changed their eating behavior and lifestyle from the time of diagnosis, with a positive impact on treatment outcomes and quality of life.


2019 ◽  
Vol 8 (4) ◽  
Author(s):  
Anna V. Pogodina ◽  
Larisa R. Kolesnikova ◽  
Olga V. Valyavskaya ◽  
Liliya V. Zurbanova ◽  
Lyubov V. Rychkova

Objective — To establish significant associations between periodontium status, circadian blood pressure (BP) profile and cardiovascular risk factors in adolescents with high BP. Material and Methods — The cross-sectional study involved 113 adolescents (78 boys) aged 10 to 17 years, with a BP level (during repeated office measurements) of ≥95 percentile for age, height and sex, or ≥140/90 mmHg in adolescents older than 16 years. All adolescents were subjected to 24-hour blood pressure monitoring, anthropometric measurements, laboratory blood tests (lipids, uric acid, alanine aminotransferase, aspartate aminotransferase, fasting glucose), echocardiography (left ventricular myocardial mass index, relative wall thickness), assessment of the stage of puberty, dental examination (complex periodontal index (CPI), oral hygiene index). The association between the periodontium status and cardiovascular risk factors was assessed using univariant and multiple regression analysis, adjusted by sex, age, Tanner stage, body mass index, and oral hygiene index. Results — Clinical features of periodontitis were found in 32.7% of adolescents. Multiple regression analysis showed the presence of significant associations of CPI with the levels of systolic, mean and pulse BP during 24 hours (β=0.42, р=0.0001; β=0.31, р=0.003 and β=0.26, р=0.018, respectively), diastolic BP in the daytime (β=0.23, р=0.019), as well as the indices of load with high systolic BP within 24 hours (β=0.42, р=0.0001) and diastolic BP in the daytime (β=0.25, р=0.006). None of the other cardiovascular risk factors showed meaningful relationships with periodontium status in the multivariate analysis. Conclusion — The relationship between periodontium status and blood pressure level exists already in adolescence. That may, on the one hand, justify assessment of periodontium status and (if necessary) timely implementation of prophylactic measures in adolescents with high blood pressure and, on the other hand, recommend BP assessment in adolescents with diagnosed periodontitis.


Author(s):  
Renata Aparecida Rodrigues de Oliveira ◽  
Osvaldo Costa Moreira ◽  
Rômulo José Mota Júnior ◽  
João Carlos Bouzas Marins

Abstract Body adiposity index (BAI) is a relatively recent evaluation method for the diagnosis of overweight and obesity, which takes into account simple measures. The aim of this study was to verify the association between BAI and cardiovascular risk factors in teachers. A cross-sectional study was conducted with 495 teachers from the city of Viçosa-MG. BAI, body mass index (BMI), abdominal circumference (AC), waist-to-hip ratio (WtHR), body fat percentage (%BF), systolic and diastolic blood pressure, fasting glucose, total cholesterol and triglycerides were evaluated. Associations between BAI (independent variable) and other variables (dependent variable) were evaluated through simple linear regression. Of the total participants, 32.12% presented high BAI and higher anthropometric, blood pressure and biochemical values (p<0.05). Higher percentage of high BAI was observed among men and with advancing age. Linear regression analysis showed positive association between BAI and other anthropometric measurements (p<0.001), with glucose (R²=0.024; p=0.001) and total cholesterol (R²=0.028; p<0.001). BAI was positively associated with the other anthropometric measures (BMI, %BF, AC and WtHR), and with the glucose and total cholesterol of evaluated teachers. Higher BAI was observed among men and with advancing age.


1994 ◽  
Vol 72 (01) ◽  
pp. 058-064 ◽  
Author(s):  
Goya Wannamethee ◽  
A Gerald Shaper

SummaryThe relationship between haematocrit and cardiovascular risk factors, particularly blood pressure and blood lipids, has been examined in detail in a large prospective study of 7735 middle-aged men drawn from general practices in 24 British towns. The analyses are restricted to the 5494 men free of any evidence of ischaemic heart disease at screening.Smoking, body mass index, physical activity, alcohol intake and lung function (FEV1) were factors strongly associated with haematocrit levels independent of each other. Age showed a significant but small independent association with haematocrit. Non-manual workers had slightly higher haematocrit levels than manual workers; this difference increased considerably and became significant after adjustment for the other risk factors. Diabetics showed significantly lower levels of haematocrit than non-diabetics. In the univariate analysis, haematocrit was significantly associated with total serum protein (r = 0*18), cholesterol (r = 0.16), triglyceride (r = 0.15), diastolic blood pressure (r = 0.17) and heart rate (r = 0.14); all at p <0.0001. A weaker but significant association was seen with systolic blood pressure (r = 0.09, p <0.001). These relationships remained significant even after adjustment for age, smoking, body mass index, physical activity, alcohol intake, lung function, presence of diabetes, social class and for each of the other biological variables; the relationship with systolic blood pressure was considerably weakened. No association was seen with blood glucose and HDL-cholesterol. This study has shown significant associations between several lifestyle characteristics and the haematocrit and supports the findings of a significant relationship between the haematocrit and blood lipids and blood pressure. It emphasises the role of the haematocrit in assessing the risk of ischaemic heart disease and stroke in individuals, and the need to take haematocrit levels into account in determining the importance of other cardiovascular risk factors.


2020 ◽  
Vol 16 ◽  
Author(s):  
Rahil Taheri ◽  
Shahram Molavynejad ◽  
Parvin Abedi ◽  
Elham Rajaei ◽  
Mohammad Hosein Haghighizadeh

Aim: The aim of this study was to investigate the effect of dietary education on cardiovascular risk factors in patients with rheumatoid arthritis. Method: In this randomized clinical trial, 112 patients with rheumatoid arthritis were randomly assigned into two groups, intervention and control. Dietary education was provided for the intervention group in 4 sessions; anthropometric measurements, serum levels of RF, triglycerides, cholesterol, HDL, LDL, and fasting blood sugar were measured before and three months after intervention. Data was analyzed using SPSS software and appropriate statistical tests. Results: The mean of total cholesterol (p <0.001), triglycerides (p = 0.004), LDL (p <0.001), systolic blood pressure (p = 0.001), diastolic blood pressure (p = 0.003), FBS and BMI (p <0.001) were decreased significantly in the intervention group after education compared the control group. Conclusion: Traditional care for rheumatoid arthritis patients is not enough. Patients need more education in order to improve their situation.


2010 ◽  
Vol 50 (4) ◽  
pp. 220
Author(s):  
Nadia Dwi Insani ◽  
Sukman Tulus Putra ◽  
Agus Firmansyah

Background Cardiovascular diseases remain the leading cause of death worldwide. Atherosclerotic process increases rapidly during adolescence. Physical activity is considered important in this period to modify cardiovascular risk factors, thus preventing disease in the future.Objective To determine whether different physical activity status in adolescence can influence body mass index (BMBMI), waist-to-hip ratio, blood pressure (BP), and blood lipid profile.Methods This was a cross-sectional descriptive study, conducted from December 2009 to January 2010. Adolescents who fulfilled the study criteria were classified into high and low physical activity category. Further examination including body mass index, waist-to-hip ratio, blood pressure, and blood lipid profile were performed.Results Adolescents with high physical activity had higher, but statistically insignificant, BMBMI compared to adolescents in the P=0.493] and significantly lower waist-to-hip ratio [0.80 (range 0.73-0.9) vs.. 0.82 (range 0.7-0.9), P=0.019]. Difference in BP was not statistically significant between both groups [diastolic BP (70 (range 60-90) mmHg vs. 70 (range 60-90) mmHg, P=0.148; systolic BP 100 (range 90-130) mmHg vs. 100 (range 90-140) mmHg, P=0.228)]. Blood lipid examination in the high activity group showed significantly higher HDL cholesterol and lower triglyceride compared to the low activity group [HDL 59.8 (SD 11.8) mg/dL vs. 54.7 (SD 8.9) mg/dL; p=0.044; triglyceride: 60 (range 32-203) mmHg vs. 82 (range 37-198) mmHg, P=0.014]. Total and LDL cholesterol [total cholesterol 169.8 (SD 28.6) mmHg vs. 181.2 (SD 30.8) mmHg, P=0.107; LDL 103.6 (SD 26.8) mmHg vs. 114.1 (SD 27.3) mmHg, P=0.100] were lower in the high activity group but not statistically different in both groups.Conclusions Adolescents with high physical activity show less cardiovascular risk factors compared to those in the low physical activity group.


BMC Medicine ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Jessica Gong ◽  
Katie Harris ◽  
Sanne A. E. Peters ◽  
Mark Woodward

Abstract Background Sex differences in major cardiovascular risk factors for incident (fatal or non-fatal) all-cause dementia were assessed in the UK Biobank. The effects of these risk factors on all-cause dementia were explored by age and socioeconomic status (SES). Methods Cox proportional hazards models were used to estimate hazard ratios (HRs) and women-to-men ratio of HRs (RHR) with 95% confidence intervals (CIs) for systolic blood pressure (SBP) and diastolic blood pressure (DBP), smoking, diabetes, adiposity, stroke, SES and lipids with dementia. Poisson regression was used to estimate the sex-specific incidence rate of dementia for these risk factors. Results 502,226 individuals in midlife (54.4% women, mean age 56.5 years) with no prevalent dementia were included in the analyses. Over 11.8 years (median), 4068 participants (45.9% women) developed dementia. The crude incidence rates were 5.88 [95% CI 5.62–6.16] for women and 8.42 [8.07–8.78] for men, per 10,000 person-years. Sex was associated with the risk of dementia, where the risk was lower in women than men (HR = 0.83 [0.77–0.89]). Current smoking, diabetes, high adiposity, prior stroke and low SES were associated with a greater risk of dementia, similarly in women and men. The relationship between blood pressure (BP) and dementia was U-shaped in men but had a dose-response relationship in women: the HR for SBP per 20 mmHg was 1.08 [1.02–1.13] in women and 0.98 [0.93–1.03] in men. This sex difference was not affected by the use of antihypertensive medication at baseline. The sex difference in the effect of raised BP was consistent for dementia subtypes (vascular dementia and Alzheimer’s disease). Conclusions Several mid-life cardiovascular risk factors were associated with dementia similarly in women and men, but not raised BP. Future bespoke BP-lowering trials are necessary to understand its role in restricting cognitive decline and to clarify any sex difference.


2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
H Bergum ◽  
I Sandven ◽  
TO Klemsdal

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): The Norwegian health department Background The evidence of the long-term effects of multiple lifestyle intervention on cardiovascular risk is uncertain. We aimed to summarize the evidence from randomized clinical trials examining the efficacy of lifestyle intervention on major cardiovascular risk factors in subjects at high cardiovascular risk. Methods  Eligible trials investigated the impact of lifestyle intervention versus usual care with minimum 24 months follow-up, reporting more than one major cardiovascular risk factor. A literature search updated April 15, 2020 identified 12 eligible studies. The results from individual trials were combined using fixed and random effect models, using the standardized mean difference (SMD) to estimate effect sizes. Small-study effect was evaluated, and heterogeneity between studies examined by subgroup and meta-regression analyses considering patient- and study-level variables. Results  Small-study effect was not identified. Lifestyle intervention reduced systolic blood pressure modestly with an estimated SMD of -0.13, 95% confidence interval (CI): -0.21 to -0.04, with moderate heterogeneity (I² = 59%), corresponding to a mean difference of approximately 2 mmHg (MD = -1.86, 95% CI: -3.14 to -0.57, p = 0.0046). This effect disappeared in the subgroup of trials judged at low risk of bias (SMD = 0.02, 95% CI: -0.08 to 0.11). For the outcome total cholesterol SMD was -0.06, 95% CI: -0.13 to 0.00, with no heterogeneity (I² = 0%), indicating no effect of the intervention. Conclusion  Lifestyle intervention resulted in only a modest effect on systolic blood pressure and no effect on total cholesterol after 24 months. Further lifestyle trials should consider the challenge of maintaining larger long-term benefits to ensure impact on cardiovascular outcomes.


2020 ◽  
Vol 8 ◽  
Author(s):  
Chen Dong ◽  
Minhui Zhu ◽  
Luguang Huang ◽  
Wei Liu ◽  
Hengxin Liu ◽  
...  

Abstract Background Tissue expansion is used for scar reconstruction owing to its excellent clinical outcomes; however, the complications that emerge from tissue expansion hinder repair. Infection is considered a major complication of tissue expansion. This study aimed to analyze the perioperative risk factors for expander infection. Methods A large, retrospective, single-institution observational study was carried out over a 10-year period. The study enrolled consecutive patients who had undergone tissue expansion for scar reconstruction. Demographics, etiological data, expander-related characteristics and postoperative infection were assessed. Univariate and multivariate logistic regression analysis were performed to identify risk factors for expander infection. In addition, we conducted a sensitivity analysis for treatment failure caused by infection as an outcome. Results A total of 2374 expanders and 148 cases of expander infection were assessed. Treatment failure caused by infection occurred in 14 expanders. Multivariate logistic regression analysis identified that disease duration of ≤1 year (odds ratio (OR), 2.07; p &lt; 0.001), larger volume of expander (200–400 ml vs &lt;200 ml; OR, 1.74; p = 0.032; &gt;400 ml vs &lt;200 ml; OR, 1.76; p = 0.049), limb location (OR, 2.22; p = 0.023) and hematoma evacuation (OR, 2.17; p = 0.049) were associated with a high likelihood of expander infection. Disease duration of ≤1 year (OR, 3.88; p = 0.015) and hematoma evacuation (OR, 10.35; p = 0.001) were so related to high risk of treatment failure. Conclusions The rate of expander infection in patients undergoing scar reconstruction was 6.2%. Disease duration of &lt;1 year, expander volume of &gt;200 ml, limb location and postoperative hematoma evacuation were independent risk factors for expander infection.


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