THE VALUE OF NARROW BAND IMAGING ENDOSCOPY IN DIAGNOSIS OF HYPOPHARYNGEAL AND LARYNGEAL CANCER AND FOLLOWING - UP POST TREATMENT

2018 ◽  
Vol 8 (6) ◽  
pp. 114-122
Author(s):  
Thong Le Chi ◽  
Thanh Dang ◽  
Nam Tran Phuong

Background: To evaluate the value of narrow band imaging (NBI) endosocopy in diagnosis of hypopharyngeal and laryngeal cancer and following – up post treatment. Material and methods: A total of 75 patients included 36 patients with hypopharyngeal cancer and 39 patients with laryngeal cancer who had diagnosed at Department of Otoloryngology – Hue Central Hospital from 5/2017 to 5/2018. A prospective cohort study was conducted. Results: The age group 51 - 60 years occurred most often, 33.3%, the mean age was 62.1 ± 13.4. The UICC stage III was 65.3%. Tumor was in ulcerlarative and infiltrate form (89.4%), edema and inflammation of magrin tumor (41.3%), invasive (58.7%). Intrapapillary capillary loops – IPCL - type V was predominant, type V-n was 46.7%. The tumor with IPCL type V-n had strong enhancement (51.3%) and moderate enhancement (44.4%) after contrast medium injection on CT scan. One month after treatment, there were 33.3% of tumor – free, 53.7% of mucosal edema and 13% tumor size-decreasing on NBI image. Conclusion: NBI endoscopy is an useful tool for diagnosing of hypopharyngeal and laryngeal cancer and following – up post treatment. Key words: narrow band imaging endoscopy, hypopharyngeal cancer, laryngeal cancer

2010 ◽  
Vol 125 (3) ◽  
pp. 288-296 ◽  
Author(s):  
X-G Ni ◽  
S He ◽  
Z-G Xu ◽  
L Gao ◽  
N Lu ◽  
...  

AbstractObjective:To investigate the characteristics of the laryngeal mucosal microvascular network in suspected laryngeal cancer patients, using narrow band imaging, and to evaluate the value of narrow band imaging endoscopy in the early diagnosis of laryngeal precancerous and cancerous lesions.Patients and methods:Eighty-five consecutive patients with suspected precancerous or cancerous laryngeal lesions were enrolled in the study. Endoscopic narrow band imaging findings were classified into five types (I to V) according to the features of the mucosal intraepithelial papillary capillary loops assessed.Results:A total of 104 lesions (45 malignancies and 59 nonmalignancies) was detected under white light and narrow band imaging modes. The sensitivity and specificity of narrow band imaging in detecting malignant lesions were 88.9 and 93.2 per cent, respectively. The intraepithelial papillary capillary loop classification, as determined by narrow band imaging, was closely associated with the laryngeal lesions' histological findings. Type I to IV lesions were considered nonmalignant and type V lesions malignant. For type Va lesions, the sensitivity and specificity of narrow band imaging in detecting severe dysplasia or carcinoma in situ were 100 and 79.5 per cent, respectively. In patients with type Vb and Vc lesions, the sensitivity and specificity of narrow band imaging in detecting invasive carcinoma were 83.8 and 100 per cent, respectively.Conclusion:Narrow band imaging is a promising approach enabling in vivo differentiation of nonmalignant from malignant laryngeal lesions by evaluating the morphology of mucosal capillaries. These results suggest endoscopic narrow band imaging may be useful in the early detection of laryngeal cancer and precancerous lesions.


2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P252-P141
Author(s):  
Masahiko Higashikawa

Objectives The Narrow Band Imaging (NBI) is an illumination method for medical endoscopes that can visualize the micro-vascular structure of the organ surface. The effectiveness of NBI has been reported in detecting the oropharyngeal and hypopharyngeal neoplasm lesion. The aim of this study is to identify the usefulness of NBI in laryngeal lesion, especially in observing cases of post-operated or post-irradiated early laryngeal cancers. Methods 16 patients of early laryngeal cancer after treatment for at least 6 months were entered in this study: 1 case of T1s, 8 cases of T1a, 3 cases of T1b, and 4 cases of T2. 3 cases of T1a underwent cordectomy under direct laryngoscope using KTP laser. 13 cases were treated with irradiation. Results The cases for which NBI was suggested to be useful were: T1b, undergoing laser surgery, supra-glottic carcinoma, appearing hyper-adduction of the false vocal fold during phonating, and causing severe mucosal edema after irradiation. Conclusions NBI system may play an important role in the observation of post-therapy of early laryngeal cancer.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Taro Iwatsubo ◽  
Ryu Ishihara ◽  
Yasushi Yamasaki ◽  
Yusuke Tonai ◽  
Kenta Hamada ◽  
...  

Abstract Background The current virtual chromoendoscopy equipment cannot completely detect superficial squamous cell carcinoma (SCC) in the esophagus, despite its development in the recent years. Thus, in this study, we aimed to elucidate the appropriate air volume during endoscopic observation to improve the visibility of esophageal SCC. Methods This retrospective study included a total of 101 flat type esophageal SCCs identified between April 2017 and January 2019 at the Department of Gastrointestinal Oncology, Osaka International Cancer Institute. Video images of narrow band imaging (NBI) under both less-air and standard-air conditions were recorded digitally. Videos were evaluated by five endoscopists. Relative visibility between less-air and standard-air conditions of the brownish area, brownish color change of the epithelium, and dilated intrapapillary capillary loop (IPCL) were graded as 5 (definitely better under less-air condition) to 1 (definitely worse under less-air condition), with 3 indicating average visibility (equivalent to standard-air observation). Results The mean (standard deviation) visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs under less-air condition were 3.94 (0.58), 3.73 (0.57), and 4.13 (0.60), respectively, which were significantly better than that under standard-air condition (p < 0.0001). Esophageal SCC evaluated as ≥ 4 in the mean visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs accounted for 50% (51/101 lesions), 34% (34/101 lesions), and 67% (68/101 lesions), respectively. Conclusions The present results suggested that NBI with less air might improve the visibility of flat type esophageal SCC compared with NBI with standard air. Less-air NBI observation may facilitate the detection of flat type esophageal SCC. Trial registration The present study is a non-intervention trial.


2009 ◽  
Vol 69 (5) ◽  
pp. AB256 ◽  
Author(s):  
Tamotsu Matsuhashi ◽  
Hirohide Ohnishi ◽  
Mario Jin ◽  
Hirosato Mashima ◽  
Yoshihiko Inaba ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Michal Zabrodsky ◽  
Petr Lukes ◽  
Eva Lukesova ◽  
Jan Boucek ◽  
Jan Plzak

Narrow band imaging is considered a significant improvement in the possibility of detecting early mucosal lesion of the upper aerodigestive tract. Early detection of mucosal neoplastic lesions is of utmost importance for patients survival. There is evidence that, especially in patients previously treated by means of curative radiotherapy or chemoradiotherapy, the early detection rate of recurrent disease is quite low. The aim of this study was to prove whether the videoendoscopy coupled with NBI might help detect recurrent or secondary tumors of the upper aerodigestive tract. 66 patients previously treated by means of RT or CRT with curative intent were enrolled in the study. All patients underwent transnasal flexible videoendoscopy with NBI mode under local anesthesia. When a suspicious lesion was identified in an ambulatory setting, its nature was proved histologically. Many of these changes were not identifiable by means of conventional white light (WL) endoscopy. The accuracy, sensitivity, specificity, and positive and negative predictive value of the method are very high (88%, 92%, 76%, 96%, and 91%, resp.). Results demonstrate that outpatient transnasal endoscopy with NBI is an excellent method for the follow-up of patients with carcinomas of the larynx and the hypopharynx primarily treated with radiotherapy.


2021 ◽  
Author(s):  
Muhammad Adeel Azam ◽  
Claudio Sampieri ◽  
Alessandro Ioppi ◽  
Stefano Africano ◽  
Alberto Vallin ◽  
...  

1986 ◽  
Vol 116 ◽  
pp. 231-232
Author(s):  
M.M. Shara ◽  
A.F.J. Moffat

We have completed a survey of the closest giant spiral galaxy beyond our own for Wolf-Rayet stars, using narrow band imaging techniques (cf. Moffat and Shara 1983, Ap. J., 273, 544). About 90% of the main body of M31 has been thoroughly searched to B ≅ 21.5 (MB ≅ −3.5) to a level of emission line equivalent width We(HeII 4686 A) ≳ 60 A. We do not expect interstellar extinction to be a limiting factor in the detection of WR stars, except possibly in the localized neighborhoods of massive HII regions. The mean extinction for stars in the disk is estimated to be AB ≲ 0.9 mag. Although some weak-line WN stars will have escaped detection, the survey should be complete for WC stars.


2015 ◽  
Vol 61 (3) ◽  
pp. 161-164
Author(s):  
Diac Andreea Raluca ◽  
Brusnic Olga ◽  
Gabos Gabriella ◽  
Onisor Danusia ◽  
Drasoveanu Silvia Cosmina ◽  
...  

Abstract Objective. Assessment of the histological and endoscopic features of the colo-rectal polyps is requered for the application of the new diagnostic and therapeutical strategies in the managment of the diminutive polyps. Methods. This paper is a descriptive retrospective study on 52 pacients reffered for colonoscopy in Gastroenterology Clinic – Clinical County Hospital Targu Mures from January until September 2014. 80 polyps were assessed. Narrow band imaging examination targeted on the protrusive lezions allowed NICE (Narrow Band Imaging International Colorectal Endoscopic) classification and corroboration of the histology prediction and pathological assessment. Results. Polyp detection rate was 48,58%, given the quality of bowel preparation in hospital fair in 84,5%. The predominant histological type was the tubular adenoma (46,25%), and 40% of the polyps were located in the sigmoid. Among the diminutive polyps, 58,33% were hyperplastic(p<0,0001), mainly in the recto-sigmoid (66,67%); the incidence of high grade displasia or cancer was 0. Real –time prediction of the histology of the colorectal polyps using NBI established: NICE 1: 19 polpyps, histology- 16 hyperplastic, (p<0,0001, sensitivity: 100%, specificity: 95%), NICE 2: 59 polyps, histology- 53 adenomatous, (p<0,0001, sensitivity: 96%, specificity: 76%), NICE 3: 2 polyps- histology-cancer. Conclusions. We did not observe any distribution pattern in the topography of the diminutive polyps. Histologicaly the predominant type was the hyperplastic type. NBI was accurate in real-time prediction of the histology of the colo-rectal polyps. The results are relevant for application of the new strategies in the managment of the diminutive polyps.


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