STUDY OF RIGHT VENTRICULAR DP/DT INDEX IN PATIENT WITH MITRAL STENOSIS BY DOPPLER ECHOCARDIOGRAPHY

2018 ◽  
Vol 8 (3) ◽  
pp. 19-30
Author(s):  
Thai Nguyen Quoc ◽  
Vu Nguyen Anh

Objectives: To use echocardiographic dP/dt to assess the right ventricular function in patients with mitral stenosis. Subjects and methods: 48 patients with pulmonary hypertension due to mitral stenosis with everage age of 52.75 ± 13.09 years, were hospitalized in Department of Internal Cardiology and Cardiothoracic Department of Hue Central Hospital about time 3/2015 to 7/2017. All of patients had been measured right ventricular dP/dt index by Doppler echocardiograph. The method of research is a cross sectional study. Result: DP/dt should be reduced to the severity of pulmonary hypertension in patients with mitral stenosis. There was a statistically significant difference between right ventricular dP/dt of patients with mild to moderate systolic pulmonary hypertension with severe systolic pulmonary hypertension patients. There was a very negative correlation between right ventricular dP/dt rate and NYHA heart failure classification (r = -0.524 and p<0.0001), the negative correlation between right ventricular dP/dt and systolic pulmonary artery pressure (r = - 0.599 and p<0.0001). Positive correlation between right ventricular dP/dt and mitral valve area (r = 0.341 and p<0.05) and positive correlation between right ventricular dP/dt and TAPSE (r = 0.538 and p <0.001). Conclusion: dP/dt may be used to evaluate right ventricular function in patients with pulmonary hypertension due to mitral stenosis. Key words: Tricuspid Annular Plane Systolic Excursion (TAPSE), right ventrical dP/dt

2019 ◽  
Vol 113 (8) ◽  
pp. 489-496
Author(s):  
Igoche D Peter ◽  
Mustafa O Asani ◽  
Shehu U Abdullahi ◽  
Ibrahim Aliyu ◽  
Stephen K Obaro ◽  
...  

Abstract Background Pulmonary hypertension (PH), a complication of sickle cell anaemia (SCA), results in considerable morbidity. This study aims to determine the prevalence and associations of echocardiography-suggested PH in children with SCA. Methods We performed a cross-sectional comparative study involving 100 systematically sampled SCA subjects 3–14 y of age in their steady state with matched haemoglobin AA phenotype controls. Clinical, laboratory and echocardiography data (including tricuspid regurgitation velocity [TRV], mean pulmonary arterial pressure [mPAP] and tricuspid annular plane systolic excursion [TAPSE]) were obtained from all patients. Statistical analyses were performed using SPSS version 22 (IBM, Armonk, NY, USA). A p-value <0.05 was considered statistically significant. Results Of the 100 SCA subjects studied, 22 (22%) had echocardiographic findings suggestive of PH compared with none in the controls. The median TAPSE was significantly lower in the PH group (2.55 cm [interquartile range {IQR} 2.2–2.8]) compared with the no PH group (2.77 cm [IQR 2.4–3.2]) (p=0.03). No significant correlation existed between mPAP and age, nor any laboratory parameters studied. The odds ratio (OR) suggested PH significantly increased with an increase in the frequency of hospitalizations for vaso-occlusive crises within a 12-month period (OR 15.15 [95% CI 1.57 to 146.35], p=0.02) and a lifetime history of blood transfusion (OR 5.44 [95% CI 1.09 to 27.24], p=0.04). Conclusions Echocardiography-suggested PH is common in children with SCA and is associated with poorer right ventricular function, frequent vaso-occlusive crises and blood transfusions.


Diagnostics ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1110
Author(s):  
Ekkehard Grünig ◽  
Christina A. Eichstaedt ◽  
Rebekka Seeger ◽  
Nicola Benjamin

Various parameters reflecting right heart size, right ventricular function and capacitance have been shown to be prognostically important in patients with pulmonary hypertension (PH). In the advanced disease, patients suffer from right heart failure, which is a main reason for an impaired prognosis. Right heart size has shown to be associated with right ventricular function and reserve and is correlated with prognosis in patients with PH. Right ventricular reserve, defined as the ability of the ventricle to adjust to exercise or pharmacologic stress, is expressed by various parameters, which may be determined invasively by right heart catheterization or by stress-Doppler-echocardiography as a noninvasive approach. As the term “right ventricular contractile reserve” may be misleading, “right ventricular output reserve” seems desirable as a preferred term of increase in cardiac output during exercise. Both right heart size and right ventricular reserve have been shown to be of prognostic importance and may therefore be useful for risk assessment in patients with pulmonary hypertension. In this article we aim to display different aspects of right heart size and right ventricular reserve and their prognostic role in PH.


1991 ◽  
Vol 21 (1) ◽  
pp. 24
Author(s):  
Yang Soo Jang ◽  
Seung Yun Cho ◽  
Nam Sik Chung ◽  
Han Soo Kim ◽  
Sung Oh Whang ◽  
...  

2014 ◽  
Vol 05 (12) ◽  
pp. 674-680 ◽  
Author(s):  
V. S. Bharathi ◽  
Adikesava Naidu Otikunta ◽  
Y. V. Subbareddy ◽  
K. Laxman Rao ◽  
Syed Imamuddin ◽  
...  

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