STUDY ON CLINICAL CHARACTERISTICS OF HAND FOOT AND MOUTH DISEASE IN HUE CENTRAL HOSPITAL

2014 ◽  
pp. 37-40
Author(s):  
Nu Van Anh Ton ◽  
Din Rmah
Keyword(s):  
Clinical Characteristics ◽  
Clinical Manifestations ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Test Method ◽  
Central Hospital ◽  
Cross Sectional ◽  
Study Results ◽  
Foot And Mouth

Objectives: Hand, foot and mouth disease (HFMD) caused by enterovirus, is a common infection in children. HFMD caused by enterovirus 71 can cause some serious complications, such as encephalitis-meningitis, myocarditis, pulmonary edema. The early detection of clinical manifestations of severe contribute to reducing mortality. So aim of this study to describe the clinical characteristics of hand foot and mouth disease in the Department of Pediatrics at Hue Central Hospital. Methods: Random sampling of all hospitalized patients from 1/2/2012 to 31/1/2013 diagnosed HFMD accompanied EV71 serum test. Method of cross-sectional descriptive study. Results and conclusions: with 441 patients admitted Hue Pediatrics Centre, 41,0% cause by EV71 and 59,0% cause by other enterovirus. 97,5% are under 5 years, male/female is 1,15/1. 68,5% coutryside. Almost patients admitted in 2rd and 3rd day (57.1%). Hospitalized reasons are fever (95,5%) and erythema rash. Majority of patients are grade 1 and 2a (87.3%). Grade 3 and 4 only (4.5%). Erythema higher proportion of vesicle, rash on foot is common.

scholarly journals The different symptoms determining management of hand foot and mouth disease and primary varicella zoster infection

2019 ◽  
Vol 52 (1) ◽  
pp. 32
Author(s):  
Maharani Laillyza Apriasari
Keyword(s):  
Clinical Manifestations ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
The Body ◽  
Upper Lip ◽  
Varicella Zoster ◽  
Foot And Mouth ◽  
Hands And Feet ◽  
Varicella Zoster Infection

Background: Hand, foot and mouth disease (HFMD) is a medical condition endemic among children in South-East Asia, including Indonesia and, more specifically, Banjarmasin – the capital of South Sulawesi. The disease is mediated by Enterovirus 71 and Coxsackievirus 16 which attack the oral cavity, hands, feet, buttocks and genital areas. One differential diagnosis of this disease is Primary Varicella Zoster infection. Both diseases have similar clinical symptoms but different etiologies which can precipitate errors in the administration of therapy Purpose: To elucidate the distinction between HFMD and Primary varicella zoster infection. Case: An 8 year-old male sought treatment complaining of ulcers on the upper maxillary gingiva followed by the appearance of itchy and painful lesions affecting the nose, upper lip, hands and feet. The patient’s mother reported his history of 39oC fever followed by the development of red spots and ulcers on the face, hands and feet which caused itching. Clinically, it is similar to Primary varicella zoster infection which can affect any part of the body. The patient only used an immunomodulator once a day and was actively seeking available healthcare. Case management: Extraoral examination confirmed the presence of multiple erythematous vesicles and ulcers, 2 mm in diameter, which caused a sensation of itching around the nose and upper lip region. Multiple painful and itchy red macules and vesicles, 3-6 mm in diameter, appeared not only on the patient’s palms, back of the hands and feet. Intraoral examination of the right maxillary gingiva revealed multiple painful ulcers, 1-2 mm in diameter and yellowish in appearance, surrounded by erythema. The results of history-taking implied that no lesions appeared on other parts of the body. Conclusion: While these conditions share similar clinical manifestations, their contrasting etiologies require different treatments. The ultimate diagnosis can be determined clinically by the dentist, thereby preventing errors in the administration of therapy.

scholarly journals Awareness Of Hand, Foot And Mouth Disease Among Dental Students

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 952-955
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy
Keyword(s):  
College Students ◽  
Large Scale ◽  
Clinical Manifestations ◽  
Foot And Mouth Disease ◽  
Professional Associations ◽  
Dental Students ◽  
Mouth Disease ◽  
Cross Sectional ◽  
Foot And Mouth ◽  
Treatment Measures

Hand, Foot and Mouth Disease (HFM) is often a potentially infectious condition primarily caused through enteroviruses. Clinical manifestations involve erythematous papules mostly on arms, legs, and even in the oral cavity, followed by prodromal effects such as myalgia, moderate fever, and abdominal distress. This survey was conducted to assess hand, foot, and mouth disease awareness among dental students. This was a questionnaire-based cross-sectional type of survey comprising 100 dental college students in Chennai. A self-designed questionnaire containing ten queries based on the knowledge and awareness about Hand, foot and mouth disease (HFMD) among dental college students. Questionnaires were distributed through an online website survey planet. After the responses were received from 100 participants, data were collected and analysed.47% are aware of HFMD. 34%are aware of the clinical manifestation of HFMD. 31%Are aware of the mode of transmission of HFMD. 26% are aware of the preventive measures against HFMD.18%. Are aware of the incubation period of HFMD. 24%aware of treatment measures for HFMD. This study found the dental students displayed less knowledge and understanding of HFMD. Even, there are few differences in knowledge and behaviours that require enhancement. Large-scale health awareness initiatives of HFMD should be implemented by professional associations in order to fill these gaps and improve awareness in order to positively impact their attitudes.

scholarly journals DNA methylation and SNP in IFITM3 are correlated with hand, foot and mouth disease caused by enterovirus 71

2021 ◽  
Vol 105 ◽  
pp. 199-208
Author(s):  
Mei Li ◽  
Ya-Ping Li ◽  
Hui-Ling Deng ◽  
Mu-Qi Wang ◽  
Yuan Chen ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Foot And Mouth

scholarly journals Advances in Antigenic Peptide-Based Vaccine and Neutralizing Antibodies against Viruses Causing Hand, Foot, and Mouth Disease

2019 ◽  
Vol 20 (6) ◽  
pp. 1256 ◽  
Author(s):  
Mohd Anasir ◽  
Chit Poh
Keyword(s):  
Neutralizing Antibodies ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Antigenic Peptide ◽  
Effective Vaccine ◽  
Inactivated Vaccine ◽  
Antigenic Peptides ◽  
Foot And Mouth ◽  
Etiological Agents

Hand, foot, and mouth disease (HFMD) commonly produces herpangina, but fatal neurological complications have been observed in children. Enterovirus 71 (EV-A71) and Coxsackievirus 16 (CV-A16) are the predominant viruses causing HFMD worldwide. With rising concern about HFMD outbreaks, there is a need for an effective vaccine against EV-A71 and CV-A16. Although an inactivated vaccine has been developed against EV-A71 in China, the inability of the inactivated vaccine to confer protection against CV-A16 infection and other HFMD etiological agents, such as CV-A6 and CV-A10, necessitates the exploration of other vaccine platforms. Thus, the antigenic peptide-based vaccines are promising platforms to develop safe and efficacious multivalent vaccines, while the monoclonal antibodies are viable therapeutic and prophylactic agents against HFMD etiological agents. This article reviews the available information related to the antigenic peptides of the etiological agents of HFMD and their neutralizing antibodies that can provide a basis for the design of future therapies against HFMD etiological agents.

scholarly journals Meteorological factors affect the hand, foot, and mouth disease epidemic in Qingdao, China, 2007–2014

2016 ◽  
Vol 144 (11) ◽  
pp. 2354-2362 ◽  
Author(s):  
F. C. JIANG ◽  
F. YANG ◽  
L. CHEN ◽  
J. JIA ◽  
Y. L. HAN ◽  
...  
Keyword(s):  
Meteorological Factors ◽  
Enterovirus 71 ◽  
Rank Correlation ◽  
Foot And Mouth Disease ◽  
Late Summer ◽  
Atmospheric Temperature ◽  
Early Spring ◽  
Mouth Disease ◽  
Foot And Mouth ◽  
Spearman Rank Correlation Analysis

SUMMARYHand, foot, and mouth disease (HFMD) has caused public health concerns worldwide. We aimed to investigate the effect of meteorological factors on the HFMD epidemic in Qingdao, a port city in China. A total of 78641 cases were reported in Qingdao between January 2007 and December 2014. Of those, 71084 (90·39%) occurred in children aged 0–5 years, with an incidence of 1691·2/100000. The incidence increased from early spring, peaked between spring and summer, and decreased in late summer. Aetiological agents in all severe cases and selected mild cases were characterized by examining throat swabs. Except for enterovirus 71 (EV71) and coxsackievirus A16 (CA16), other EVs caused >50% of the HFMD cases between 2011 and 2014. EV71 was more frequent in the off-peak months than in the peak months and prone to causing more severe cases compared to CA16 (χ2 = 46·3, P < 0·001). CA10 caused more severe HFMD than did CA6 (χ2 = 20·49, P < 0·001) and all non-CA10 EVs (χ2 = 41·01, P < 0·001). Community-derived HFMD cases accounted for 65·11%. Spearman rank correlation analysis showed that HFMD incidence in children aged 0–5 years was positively correlated with atmospheric temperature (rs = 0·77, P < 0·001), relative humidity (rs = 0·507, P < 0·001), and precipitation (rs = 0·328, P < 0·001). Climate changes and CA10 surveillance in communities should be integrated into the current prophylactic programme.

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