Guidance for assessing the validity of physical fire models for obtaining fire effluent toxicity data for fire hazard and risk assessment

2021 ◽  
Keyword(s):  
Risk Assessment ◽  
Fire Hazard ◽  
Toxicity Data ◽  
Fire Models ◽  
Effluent Toxicity ◽  
Hazard And Risk ◽  
Hazard And Risk Assessment

Smoke Toxicity Data for Fire Hazard and Risk Assessment of Cable Products

2006 ◽  
Vol 3 (2) ◽  
pp. 12852
Author(s):  
RG Gann ◽  
RD Peacock ◽  
JD Averill ◽  
MR Nyden
Keyword(s):  
Risk Assessment ◽  
Fire Hazard ◽  
Toxicity Data ◽  
Smoke Toxicity ◽  
Hazard And Risk ◽  
Hazard And Risk Assessment

scholarly journals Development of the SciRAP Approach for Evaluating the Reliability and Relevance of in vitro Toxicity Data

2021 ◽  
Vol 3 ◽  
Author(s):  
Nicolas Roth ◽  
Johanna Zilliacus ◽  
Anna Beronius
Keyword(s):  
Risk Assessment ◽  
Methodological Quality ◽  
Online Survey ◽  
Human Health Risk ◽  
Reporting Quality ◽  
Test System ◽  
Toxicity Data ◽  
Hazard And Risk ◽  
Hazard And Risk Assessment

Efficient and successful integration of data generated from non-animal test methods must rely on reliable and relevant data. It is important therefore to develop tools and criteria that facilitate scientifically sound, structured, and transparent evaluation of reliability and relevance of in vitro toxicity data to efficiently inform regulatory hazard and risk assessment. The Science in Risk Assessment and Policy (SciRAP) initiative aims to promote such overarching goals. We present the work to develop and refine the SciRAP tool for evaluation of reliability and relevance of in vitro studies for incorporation on the SciRAP web-based platform (www.scirap.org). In the SciRAP approach, reliability evaluation is based on criteria for reporting quality and methodological quality, and is explicitly separated from relevance evaluation. The SciRAP in vitro tool (version 1.0) was tested and evaluated during an expert test round (April 2019-September 2020) on three in vitro studies by thirty-one experts from regulatory authorities, industry and academia from different geographical areas and with various degree of experience in in vitro research and/or human health risk assessment. In addition, the experts answered an online survey to collect their feedback about the general features and desired characteristics of the tool for further refinement. The SciRAP in vitro tool (version 2.0) was revised based on the outcome of the expert test round (study evaluation and online survey) and consists of 24 criteria for evaluating “reporting quality” (reliability), 16 criteria for “methodological quality” (reliability), and 4 items for evaluating relevance of in vitro studies. Participants were generally positive about the adequacy, flexibility, and user-friendliness of the tool. The expert test round outlined the need to (i) revise the formulation of certain criteria; (ii) provide new or revised accompanying guidance for reporting quality and methodological quality criteria in the “test compounds and controls,” “test system,” and “data collection and analysis” domains; and (iii) provide revised guidance for relevance items, as general measures to reduce inter-expert variability. The SciRAP in vitro tool allows for a structured and transparent evaluation of in vitro studies for use in regulatory hazard and risk assessment of chemicals.

scholarly journals Definitions and Concepts for Quantitative Rockfall Hazard and Risk Analysis

Geosciences ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 158
Author(s):  
Didier Hantz ◽  
Jordi Corominas ◽  
Giovanni B. Crosta ◽  
Michel Jaboyedoff
Keyword(s):  
Risk Assessment ◽  
At Risk ◽  
Failure Probability ◽  
Rockfall Hazard ◽  
Process Failure ◽  
Failure Propagation ◽  
Element At Risk ◽  
Hazard And Risk ◽  
Hazard And Risk Assessment ◽  
Definition Of

There is an increasing need for quantitative rockfall hazard and risk assessment that requires a precise definition of the terms and concepts used for this particular type of landslide. This paper suggests using terms that appear to be the most logic and explicit as possible and describes methods to derive some of the main hazards and risk descriptors. The terms and concepts presented concern the rockfall process (failure, propagation, fragmentation, modelling) and the hazard and risk descriptors, distinguishing the cases of localized and diffuse hazards. For a localized hazard, the failure probability of the considered rock compartment in a given period of time has to be assessed, and the probability for a given element at risk to be impacted with a given energy must be derived combining the failure probability, the reach probability, and the exposure of the element. For a diffuse hazard that is characterized by a failure frequency, the number of rockfalls reaching the element at risk per unit of time and with a given energy (passage frequency) can be derived. This frequency is relevant for risk assessment when the element at risk can be damaged several times. If it is not replaced, the probability that it is impacted by at least one rockfall is more relevant.

STUDY ON BISPHENOL F, A BISPHENOL A ANALOGUE, AT A DAIRY COMPANY: HEALTH HAZARD AND RISK ASSESSMENT

2021 ◽  
pp. 112334
Author(s):  
Serena Santonicola ◽  
Stefania Albrizio ◽  
Maria Carmela Ferrante ◽  
Mercogliano Raffaelina
Keyword(s):  
Risk Assessment ◽  
Bisphenol A ◽  
Health Hazard ◽  
Bisphenol F ◽  
Hazard And Risk ◽  
Hazard And Risk Assessment

Aquatic hazard and risk assessment of two selected substances produced in high volumes in the Slovak Republic

Chemosphere ◽  
1997 ◽  
Vol 34 (1) ◽  
pp. 179-190 ◽  
Author(s):  
Martin Murín ◽  
Juraj Gavora ◽  
Iveta Drastichová ◽  
Elena Dušková ◽  
Torben Madsen ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Slovak Republic ◽  
Hazard And Risk ◽  
Hazard And Risk Assessment
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