Heavy commercial vehicles and buses � Vehicle dynamics simulation and validation � Lateral dynamic stability of vehicle combinations

Background: The STE20/SPS1-related proline/alanine-rich kinase (SPAK) is a component of WNKSPAK/OSR1 signaling pathway that plays an essential role in blood pressure regulation. The function of SPAK is mediated by its highly conserved C-terminal domain (CTD) that interacts with RFXV/I motifs of upstream activators, WNK kinases, and downstream substrate, cation-chloride cotransporters. Objective: To determine and validate the three-dimensional structure of the CTD of SPAK and to study and analyze its interaction with the RFXV/I motifs. Methods: A homology model of SPAK CTD was generated and validated through multiple approaches. The model was based on utilizing the OSR1 protein kinase as a template. This model was subjected to 100 ns molecular dynamic (MD) simulation to evaluate its dynamic stability. The final equilibrated model was used to dock the RFQV-peptide derived from WNK4 into the primary pocket that was determined based on the homology sequence between human SPAK and OSR1 CTDs. The mechanism of interaction, conformational rearrangement and dynamic stability of the binding of RFQV-peptide to SPAK CTD were characterized by molecular docking and molecular dynamic simulation. Results: The MD simulation suggested that the binding of RFQV induces a large conformational change due to the distribution of salt bridge within the loop regions. These results may help in understanding the relation between the structure and function of SPAK CTD and to support drug design of potential SPAK kinase inhibitors as antihypertensive agents. Conclusion: This study provides deep insight into SPAK CTD structure and function relationship.

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Lane Departure Warning Estimation Using Yaw Acceleration

Open Engineering ◽

10.1515/eng-2021-0008 ◽

2020 ◽

Vol 11 (1) ◽

pp. 102-111

Author(s):

Em Poh Ping ◽

J. Hossen ◽

Wong Eng Kiong

Keyword(s):

Vehicle Dynamics ◽

Dynamic Responses ◽

Dynamics Simulation ◽

Steering Wheel ◽

Mathematical Representation ◽

Vehicle Speed ◽

Lane Departure Warning ◽

Model Based ◽

Lane Departure ◽

Proposed Model

AbstractLane departure collisions have contributed to the traffic accidents that cause millions of injuries and tens of thousands of casualties per year worldwide. Due to vision-based lane departure warning limitation from environmental conditions that affecting system performance, a model-based vehicle dynamics framework is proposed for estimating the lane departure event by using vehicle dynamics responses. The model-based vehicle dynamics framework mainly consists of a mathematical representation of 9-degree of freedom system, which permitted to pitch, roll, and yaw as well as to move in lateral and longitudinal directions with each tire allowed to rotate on its axle axis. The proposed model-based vehicle dynamics framework is created with a ride model, Calspan tire model, handling model, slip angle, and longitudinal slip subsystems. The vehicle speed and steering wheel angle datasets are used as the input in vehicle dynamics simulation for predicting lane departure event. Among the simulated vehicle dynamic responses, the yaw acceleration response is observed to provide earlier insight in predicting the future lane departure event compared to other vehicle dynamics responses. The proposed model-based vehicle dynamics framework had shown the effectiveness in estimating lane departure using steering wheel angle and vehicle speed inputs.

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Construction of a Rational Tire Model for High Fidelity Vehicle Dynamics Simulation Under Extreme Driving and Environmental Conditions

ASME 2010 10th Biennial Conference on Engineering Systems Design and Analysis, Volume 3 ◽

10.1115/esda2010-24487 ◽

2010 ◽

Cited By ~ 1

Author(s):

S. C¸ag˘lar Bas¸lamıs¸lı ◽

Selim Solmaz

Keyword(s):

Vehicle Dynamics ◽

Dynamics Simulation ◽

High Fidelity ◽

Tire Model ◽

Dynamics Model ◽

Vehicle Model ◽

Prospective Design ◽

Magic Formula ◽

Rational Models ◽

Simulation Results

In this paper, a control oriented rational tire model is developed and incorporated in a two-track vehicle dynamics model for the prospective design of vehicle dynamics controllers. The tire model proposed in this paper is an enhancement over previous rational models which have taken into account only the peaking and saturation behavior disregarding all other force generation characteristics. Simulation results have been conducted to compare the dynamics of a vehicle model equipped with a Magic Formula tire model, a rational tire model available in the literature and the present rational tire model. It has been observed that the proposed tire model results in vehicle responses that closely follow those obtained with the Magic Formula even for extreme driving scenarios conducted on roads with low adhesion coefficient.

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Behavioral applications of vehicle-dynamics simulation

Behavior Research Methods & Instrumentation ◽

10.3758/bf03200141 ◽

1973 ◽

Vol 5 (2) ◽

pp. 114-116

Author(s):

Kurt J. Snapper ◽

David A. Seaver

Keyword(s):

Vehicle Dynamics ◽

Dynamics Simulation

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Pension Payment as A Critical Infrastructure

Műszaki Tudományos Közlemények ◽

10.33894/mtk-2018.09.50 ◽

2018 ◽

Vol 9 (1) ◽

pp. 219-222

Author(s):

Attila Szántó ◽

Gusztáv Áron Szíki ◽

Sándor Hajdu ◽

András Gábora ◽

Kristóf Balázs Sipos

Keyword(s):

Vehicle Dynamics ◽

Critical Infrastructure ◽

Dynamics Simulation ◽

Simulation Program ◽

Technical Data ◽

The University ◽

Race Cars ◽

Pension Payment

Abstract In the following the role and contribution of vehicle dynamics simulation to the development of race cars at the Faculty of Engineering of the University of Debrecen is presented. The application of the developed simulation program for the optimization of the car’s technical data, together with the principle and method of optimization, is also described here.

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