Winter-sports equipment. Test devices for the setting of the functional unit ski/boot/binding. Requirements and tests

Background: The systematic surveillance of injuries and illness in young athletes is important to reduce the loss of training and competition time and enable continuing sports participation. However, the risk and incidence of injury and illness in tropical country athletes competing in winter sports remains unclear. Objective: To identify the incidence, severity, and causes of injuries and illness in the Thailand National Youth Team during the 10-day First Winter Children of Asia Games. Materials and Methods: In the present observational prospective cohort study, the authors used the International Olympic Committee (IOC) injury and illness surveillance system for multisport events. The injuries and illnesses of 18 Thailand athletes were collected daily by the team physician over a 10-day competition period. Results: Eight injuries and nine illnesses were reported, equating to 44.4% of the athletes sustaining at least one injury and 50% at least one illness, an incidence rate of 2.6 injuries and 7.3 illnesses per 100 athletes, respectively. The risk of sustaining an injury was highest during cross country skiing while the most common type of injury was a sprain. The upper respiratory tract was the site most affected by illness with females reporting a greater illness rate. Conclusion: The presented data constitute the basis for future analyses of injury and illness associated risk factors in winter sports, which are essential to develop and implement effective preventative strategies in tropical winter sport athletes. Keywords: Surveillance, Injury and illness, Winter sport

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Nationalism in Winter Sports Judging and Its Lessons for Organizational Decision Making

SSRN Electronic Journal ◽

10.2139/ssrn.319801 ◽

2002 ◽

Cited By ~ 1

Author(s):

Eric Zitzewitz

Keyword(s):

Decision Making ◽

Organizational Decision Making ◽

Winter Sports

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Head trauma in young recreational sledders: helmets are not compulsory in Italian law (Preprint)

10.2196/preprints.12012 ◽

2018 ◽

Author(s):

Stefania Barbieri ◽

Elisa Bertoldi ◽

Giulia Maria Cillo ◽

Rosa Maria Gaudio ◽

Rossella Snenghi ◽

...

Keyword(s):

Head Trauma ◽

Emergency Departments ◽

Emergency Services ◽

Mountain Biking ◽

Hospital Emergency ◽

Descriptive Data ◽

Winter Sports ◽

Helmet Use ◽

Italian Law ◽

Almost All

BACKGROUND Helmet use is now viewed as an essential safety measure in almost all sports involving a high risk of impact and head trauma, from horseback riding to mountain biking, rock climbing and winter sports such as skiing and snowboarding. For young skiers and snowboarders under the age of 14, the use of certified helmets is compulsory in Italian law, although no defined regulations exist for recreational sledding OBJECTIVE To review past and current regulations covering winter sports, to explore potential legal discrepancies in appraising factors related to helmet use in recreational activities by children under the age of 14, and to identify hazards connected with various types of sledding accidents METHODS Descriptive data of the cases of 16-year-old or younger adolescents injured while sledding without helmets were gathered from injury reports collected by ski patrols, pre-hospital emergency services and emergency departments, and compared with 53 cases of adolescents and children who went skiing and snowboarding wearing certified helmets, over two winter seasons (December to April, 2011-12 and 2012-13). Sledges were grouped into three categories:1) traditional wooden toboggans (hereafter called ‘traditional sleds’); 2) plastic sleds; 3) newly designed sleds (with inner tubes, plastic and hard foam sleds, snowskates, boardslides, runslides, snowblades, foam slides, etc.) RESULTS Descriptive data of the cases of 16-year-old or younger adolescents injured while sledding without helmets were gathered from injury reports collected by ski patrols, pre-hospital emergency services and emergency departments, and compared with 53 cases of adolescents and children who went skiing and snowboarding wearing certified helmets, over two winter seasons (December to April, 2011-12 and 2012-13). Sledges were grouped into three categories:1) traditional wooden toboggans (hereafter called ‘traditional sleds’); 2) plastic sleds; 3) newly designed sleds (with inner tubes, plastic and hard foam sleds, snowskates, boardslides, runslides, snowblades, foam slides, etc.) CONCLUSIONS Additional investigation of the actual dynamics of the accident, together with information on the sitting position and sled speed are required. Regulations should compel ski slope operators to improve the current level of control on sledding slopes.

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B0AT1 amino acid transporter complexed with SARS-CoV-2 receptor ACE2 forms a heterodimer functional unit: in situ conformation using radiation inactivation analysis

Function ◽

10.1093/function/zqab027 ◽

2021 ◽

Author(s):

Bruce R Stevens ◽

J Clive Ellory ◽

Robert L Preston

Keyword(s):

Amino Acid ◽

Membrane Trafficking ◽

Functional Unit ◽

Membrane Vesicles ◽

High Energy ◽

Amino Acid Transporter ◽

Neutral Amino Acid ◽

Transport Activity ◽

Acid Transporter

Abstract The SARS-CoV-2 receptor, Angiotensin Converting Enzyme-2 (ACE2), is expressed at levels of greatest magnitude in the small intestine as compared to all other human tissues. Enterocyte ACE2 is co-expressed as the apical membrane trafficking partner obligatory for expression and activity of the B0AT1 sodium-dependent neutral amino acid transporter. These components are assembled as an [ACE2: B0AT1]2 dimer-of-heterodimers quaternary complex that putatively steers SARS-CoV-2 tropism in the gastrointestinal (GI) tract. GI clinical symptomology is reported in about half of COVID-19 patients, and can be accompanied by gut shedding of virion particles. We hypothesized that within this 4-mer structural complex, each [ACE2: B0AT1] heterodimer pair constitutes a physiological “functional unit.” This was confirmed experimentally by employing purified lyophilized enterocyte brush border membrane vesicles that were exposed to increasing doses of high-energy electron radiation from a 16 MeV linear accelerator. Based on established target theory, the results indicated the presence of Na+-dependent neutral amino acid influx transport activity functional unit with target size mw = 183.7 ± 16.8 kDa in situ in intact apical membranes. Each thermodynamically stabilized [ACE2: B0AT1] heterodimer functional unit manifests the transport activity within the whole ∼345 kDa [ACE2: B0AT1]2 dimer-of-heterodimers quaternary structural complex. The results are consistent with our prior molecular docking modeling and gut-lung axis approaches to understanding COVID-19. These findings advance the understanding of the physiology of B0AT1 interaction with ACE2 in the gut, and thereby potentially contribute to translational developments designed to treat or mitigate COVID-19 variant outbreaks and/or GI symptom persistence in long-haul Post-Acute Sequelae of SARS-CoV-2 (PASC).

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