scholarly journals Novel mechanisms of neuronal and hormonal regulation of large intestinal electrolyte transport

2021 ◽  
Author(s):  
Andrew John Nickerson
Keyword(s):  
Hormonal Regulation ◽  
Electrolyte Transport ◽  
Intestinal Electrolyte Transport

scholarly journals Regulation of nephron water and electrolyte transport by adenylyl cyclases

2014 ◽  
Vol 306 (7) ◽  
pp. F701-F709 ◽  
Author(s):  
Timo Rieg ◽  
Donald E. Kohan
Keyword(s):  
Hormonal Regulation ◽  
Electrolyte Transport ◽  
Adenylyl Cyclases ◽  
Disease Pathogenesis ◽  
Membrane Bound ◽  
G Protein Coupled ◽  
Camp Formation ◽  
Distinct Membrane ◽  
Genetically Modified Animals

Adenylyl cyclases (AC) catalyze formation of cAMP, a critical component of G protein-coupled receptor signaling. So far, nine distinct membrane-bound AC isoforms (AC1-9) and one soluble AC (sAC) have been identified and, except for AC8, all of them are expressed in the kidney. While the role of ACs in renal cAMP formation is well established, we are just beginning to understand the function of individual AC isoforms, particularly with regard to hormonal regulation of transporter and channel phosphorylation, membrane abundance, and trafficking. This review focuses on the role of different AC isoforms in regulating renal water and electrolyte transport in health as well as potential pathological implications of disordered AC isoform function. In particular, we focus on modulation of transporter and channel abundance, activity, and phosphorylation, with an emphasis on studies employing genetically modified animals. As will be described, it is now evident that specific AC isoforms can exert unique effects in the kidney that may have important implications in our understanding of normal physiology as well as disease pathogenesis.

scholarly journals Effect of Senokot on rat intestinal electrolyte transport

1984 ◽  
Vol 87 (3) ◽  
pp. 503-512 ◽  
Author(s):  
M. Donowitz ◽  
J. Wicks ◽  
L. Battisti ◽  
G. Pike ◽  
R. DeLellis
Keyword(s):  
Electrolyte Transport ◽  
Intestinal Electrolyte Transport

Intestinal Electrolyte Transport and Diarrheal Disease

1989 ◽  
Vol 321 (13) ◽  
pp. 879-883 ◽  
Author(s):  
Franklin H. Epstein ◽  
Michael Field ◽  
Mrinalini C. Rao ◽  
Eugene B. Chang
Keyword(s):  
Diarrheal Disease ◽  
Electrolyte Transport ◽  
Intestinal Electrolyte Transport
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