scholarly journals The Genetic Component of Seagrass Restoration: What We Know and the Way Forwards

Water ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 829
Author(s):  
Jessica Pazzaglia ◽  
Hung Manh Nguyen ◽  
Alex Santillán-Sarmiento ◽  
Miriam Ruocco ◽  
Emanuela Dattolo ◽  
...  
Keyword(s):  
Genetic Information ◽  
Environmental Changes ◽  
Ethical Issues ◽  
Genetic Research ◽  
Gene Pools ◽  
Natural Habitats ◽  
The Face ◽  
Donor Population ◽  
Seagrass Restoration

Seagrasses are marine flowering plants providing key ecological services and functions in coasts and estuaries across the globe. Increased environmental changes fueled by human activities are affecting their existence, compromising natural habitats and ecosystems’ biodiversity and functioning. In this context, restoration of disturbed seagrass environments has become a worldwide priority to reverse ecosystem degradation and to recover ecosystem functionality and associated services. Despite the proven importance of genetic research to perform successful restoration projects, this aspect has often been overlooked in seagrass restoration. Here, we aimed to provide a comprehensive perspective of genetic aspects related to seagrass restoration. To this end, we first reviewed the importance of studying the genetic diversity and population structure of target seagrass populations; then, we discussed the pros and cons of different approaches used to restore and/or reinforce degraded populations. In general, the collection of genetic information and the development of connectivity maps are critical steps for any seagrass restoration activity. Traditionally, the selection of donor population preferred the use of local gene pools, thought to be the best adapted to current conditions. However, in the face of rapid ocean changes, alternative approaches such as the use of climate-adjusted or admixture genotypes might provide more sustainable options to secure the survival of restored meadows. Also, we discussed different transplantation strategies applied in seagrasses and emphasized the importance of long-term seagrass monitoring in restoration. The newly developed information on epigenetics as well as the application of assisted evolution strategies were also explored. Finally, a view of legal and ethical issues related to national and international restoration management is included, highlighting improvements and potential new directions to integrate with the genetic assessment. We concluded that a good restoration effort should incorporate: (1) a good understanding of the genetic structure of both donors and populations being restored; (2) the analysis of local environmental conditions and disturbances that affect the site to be restored; (3) the analysis of local adaptation constraints influencing the performances of donor populations and native plants; (4) the integration of distribution/connectivity maps with genetic information and environmental factors relative to the target seagrass populations; (5) the planning of long-term monitoring programs to assess the performance of the restored populations. The inclusion of epigenetic knowledge and the development of assisted evolution programs are strongly hoped for the future.

scholarly journals Epigenetic adaptations of the masticatory mucosa to periodontal inflammation

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Gesa M. Richter ◽  
Jochen Kruppa ◽  
H. Gencay Keceli ◽  
Emel Tuğba Ataman-Duruel ◽  
Christian Graetz ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Genetic Information ◽  
Environmental Changes ◽  
Immune Defense ◽  
Innate Immune ◽  
Fine Tuning ◽  
Mucosal Barrier ◽  
Epigenetic Changes ◽  
Periodontal Inflammation

Abstract Background In mucosal barrier interfaces, flexible responses of gene expression to long-term environmental changes allow adaptation and fine-tuning for the balance of host defense and uncontrolled not-resolving inflammation. Epigenetic modifications of the chromatin confer plasticity to the genetic information and give insight into how tissues use the genetic information to adapt to environmental factors. The oral mucosa is particularly exposed to environmental stressors such as a variable microbiota. Likewise, persistent oral inflammation is the most important intrinsic risk factor for the oral inflammatory disease periodontitis and has strong potential to alter DNA-methylation patterns. The aim of the current study was to identify epigenetic changes of the oral masticatory mucosa in response to long-term inflammation that resulted in periodontitis. Methods and results Genome-wide CpG methylation of both inflamed and clinically uninflamed solid gingival tissue biopsies of 60 periodontitis cases was analyzed using the Infinium MethylationEPIC BeadChip. We validated and performed cell-type deconvolution for infiltrated immune cells using the EpiDish algorithm. Effect sizes of DMPs in gingival epithelial and fibroblast cells were estimated and adjusted for confounding factors using our recently developed “intercept-method”. In the current EWAS, we identified various genes that showed significantly different methylation between periodontitis-inflamed and uninflamed oral mucosa in periodontitis patients. The strongest differences were observed for genes with roles in wound healing (ROBO2, PTP4A3), cell adhesion (LPXN) and innate immune response (CCL26, DNAJC1, BPI). Enrichment analyses implied a role of epigenetic changes for vesicle trafficking gene sets. Conclusions Our results imply specific adaptations of the oral mucosa to a persistent inflammatory environment that involve wound repair, barrier integrity, and innate immune defense.

scholarly journals Conservation Challenge of Dispersive Fauna

2007 ◽  
Vol 13 (2) ◽  
pp. 81 ◽  
Author(s):  
Harry F. Recher
Keyword(s):  
Environmental Changes ◽  
Full Range ◽  
Fire Regimes ◽  
Absolute Minimum ◽  
Ecological Society ◽  
The Face ◽  
Feral Animals ◽  
Fixed System ◽  
Reserve System

The six papers in this theme issue of Pacific Conservation Biology were presented at a symposium organized by the WildCountry Science Council (see Recher 2003 for an account of WildCountry) at the Adelaide meeting of the Ecological Society of Australia in 2004. The symposium theme of ?dispersive fauna? is central to the philosophy and principles of WildCountry. The WildCountry philosophy is based on the argument that the long-term conservation of continental biodiversity is not possible with a system of spatially static conservation reserves by itself. Reserves form the core of WildCountry, but cannot fully sample continental biodiversity, nor allow for the full range of movements characteristic of the biota unless the total area set aside from development far exceeds what society would see as economically or politically acceptable. Because of these limits, a static and spatially limited reserve system cannot meet the challenge of ensuring the evolutionary viability of populations and species. A challenge that becomes increasingly difficult and urgent to resolve in the face of accelerating climate change and the loss and modification of habitat through land clearing, pastoralism, changed fire regimes, and the spread of weeds and feral animals among a myriad of environmental changes driven by human endeavour across the landscape. In my view, probably greater than 50% of the continent is the absolute minimum for a fixed system of reserves to meet the needs of biodiversity conservation, but see Archer (2002) who suggests a minimum of 20% may be required simply to meet the most basic evolutionary criteria.

scholarly journals As relações entre a ecoinovação, consciência sustentável, estratégia ambiental, performance organizacional e impacto ambiental no nordeste do Brasil

2021 ◽  
Vol 20 (1) ◽  
pp. e18380
Author(s):  
Eliana Andréa Severo ◽  
Evandro Tavares de Lima ◽  
Josias Salvador dos Anjos ◽  
Silvaneide Moreira de Almeida ◽  
Sandra Regina dos Santos ◽  
...  
Keyword(s):  
Environmental Impact ◽  
Organizational Performance ◽  
Statistical Tests ◽  
Environmental Strategy ◽  
Natural Habitats ◽  
Descriptive Research ◽  
Important Relationship ◽  
The Face

Objective: This article aims to analyze the relationship between eco-innovation, sustainable awareness, environmental strategy, organizational performance and environmental impact, in the face of 210 respondents from Northeast Brazil.Methodology: The methodology used was a quantitative and descriptive research, through a survey applied to 210 respondents, analyzed using descriptive statistics, statistical tests and multiple linear regression.Originality: Original with respect to the constructs developed for the research, where three constructs (eco-innovation, sustainable awareness and organizational performance) were adapted from the literature and two (environmental strategy and environmental impact) were developed by the researchers, as it is a model that has no empirical validation in the studied environment (Northeast Brazil). Understanding the relationships between the constructs is relevant, which are paramount for companies, for reducing the environmental impact and consequently improving the quality of life of people and the planet.Results: The results show that the most important relationship occurred with the factors that influence the reduction of the environmental impact, which presents as predictors, issues associated with the environmental strategy to reduce the degradation of natural habitats and long-term sustainability.Theoretical Contributions: The study statistically validated the Constructs and scales of research, so this Framework can be used by other researchers, as well as contributing to the advancement of academic studies related to the researched themes.

scholarly journals Genetic information and insurance: some ethical issues

1997 ◽  
Vol 352 (1357) ◽  
pp. 1087-1093 ◽  
Author(s):  
Onora O'neill
Keyword(s):  
Unemployment Insurance ◽  
Genetic Information ◽  
Ethical Issues ◽  
Risk Level ◽  
Commercial Insurance ◽  
Risk Levels ◽  
The Face ◽  
It Support ◽  
And Gender ◽  
The Way

Life is risky, and insurance provides one of the best developed ways of controlling risks. By pooling, and so transferring risks, those who turn out to suffer antecedently uncertain harms can be assured in advance that they will be helped if those harms arise; they can then plan their lives and activities with confidence that they are less at the mercy of ill fortune. Both publicly organized and commercial insurance can organize the pooling of risk in ways that are beneficial for all concerned. They provide standard ways of securing fundamental ethical values such as solidarity and mutuality. Although policy holders do not know or contract with one another, each benefits from the contribution of others to a shared scheme for pooling and so controlling risk. Although there is a limit to the degree to which commercially–based insurance, where premiums depend on risk level, can go beyond mutuality towards solidarity, in practice it too often achieves a measure of solidarity by taking a broad brush approach to pooling risk However, the ordinary practices of insurance, and in particular of commercial insurance, also raise ethical questions. These may be put in simple terms by contrasting the way in which an insurance market discriminates between different people, on the basis of characteristics that (supposedly) determine their risk level, and our frequent abhorrence of discrimination, in particular on the basis on religious, racial and gender grounds. Are the discriminations on which insurance practice relies upon as standard acceptable or not? The increasing availability of genetic information, which testing (of individuals) and screening (of populations) may provide, could lend urgency to these questions. Genetic information may provide a way of obtaining more accurate assessment of individual risks to health and life. This information could be used to discriminate more finely between the risk levels of different individuals, and then to alter the availability and the costs of health, life and unemployment insurance to them. Since all of these forms of insurance bear very directly on the way most people live, it will matter to them how (if at all) insurers take account of genetic information. Will use of this information improve or damage the capacity of insurance to provide confidence in the face of uncertain harms, and help if they happen? Will it discriminate in acceptable or in unacceptable ways? Will it support or damage the sorts of mutuality and solidarity various sorts of insurance schemes have successfully institutionalized?

Challenges, Concerns, and Perspectives for Poland's Energy Transition during Global COVID-19 Pandemic

2020 ◽  
Vol 1 (2) ◽  
pp. 169-173
Author(s):  
Andrzej Lorkowski ◽  
Robert Jeszke
Keyword(s):  
Internal Energy ◽  
Energy Transition ◽  
Energy Transformation ◽  
Modern Times ◽  
Current Discussion ◽  
The Face ◽  
National Governments ◽  
The Eu ◽  
At Home

The whole world is currently struggling with one of the most disastrous pandemics to hit in modern times – Covid-19. Individual national governments, the WHO and worldwide media organisations are appealing for humanity to universally stay at home, to limit contact and to stay safe in the ongoing fight against this unseen threat. Economists are concerned about the devastating effect this will have on the markets and possible outcomes. One of the countries suffering from potential destruction of this situation is Poland. In this article we will explain how difficult internal energy transformation is, considering the long-term crisis associated with the extraction and usage of coal, the European Green Deal and current discussion on increasing the EU 2030 climate ambitions. In the face of an ongoing pandemic, the situation becomes even more challenging with each passing day.

Antiretroviral Treatment-Associated Labia Majora Lipohypertrophy: A Rare Case and Plastic Surgical Treatment Options

2017 ◽  
Vol 2 (1) ◽  
pp. 43
Author(s):  
Akmal Hisham ◽  
Devananthan Ilenghoven ◽  
Wan Syazli Wan Ahmad Kamal ◽  
Salina Ibrahim ◽  
Shah Jumaat Mohd Yussof
Keyword(s):  
Highly Active Antiretroviral Therapy ◽  
Daily Living ◽  
Treatment Options ◽  
Hiv Positive ◽  
Highly Active ◽  
Labia Majora ◽  
The Face ◽  
Central Fat

The emergence of highly active antiretroviral therapy (HAART) has revolutionized the prognosis of HIV-infected patients. However, the extended use of HAART is associated with a disfiguring complication termed lipodystrophy, a disorder of body fat maldistribution causing peripheral fat loss (lipoatrophy) and central fat accumulation (lipohypertrophy). Lipoatrophy commonly affects the face, legs, buttocks and arm, whilst lipohypertrophy frequently favours the abdomen, breast and dorsocervical region. To our knowledge, we present only the second documented case in the literature of a labia majora lipohypertrophy in a HIV-positive patient receiving long-term HAART. The severity of labial abnormality caused significant physical and functional morbidities. Labiaplasty with dermolipectomy of the labia majora and excisional lipectomy of the mons pubis was successfully performed. At a 6-month follow-up, patient had no recurrence with resolution of symptoms and resumption of normal activities of daily living (ADL).

Populist Parties in Lithuania: Curious Case of Party Order and Justice and its Leadership

2019 ◽  
Vol 7 (1) ◽  
pp. 120-137 ◽  
Author(s):  
Mindaugas Jurkynas
Keyword(s):  
Party System ◽  
Leadership Selection ◽  
Political Careers ◽  
New Parties ◽  
Selection Rules ◽  
Electoral Support ◽  
The Face

AbstractThe article discusses conceptualisation of populism, Lithuania’s party system and electoral dynamics and their relation to the sustainability of populist parties. Special attention is given to Party Order and Justice, a former populist and protest party, and its leadership, namely to the issues related to scope and competencies of a leader’s intra-partisan power, leadership selection rules and history, development of leaders’ political careers and their electoral activity. The L ithuanian party system now exhibits moderate fragmentation without centrifugal tendencies. Voter volatility is still relatively high, yet the share of new parties has dropped to zero. The protest and populist parties in Lithuania went into the margins of political establishment. Popularity of the Order and Justice party has long been connected to the formerly impeached president Rolandas Paksas. His long-term leadership in the face of plummeting electoral support and an emphasis on his political martyrdom resulted in poor electoral performances, ensuing internal squabbles and his departure. Party Order and Justice’s internal regulations, however, remained favourable to strong leadership.

Utilising Indigenous Knowledge or Crime against Humanity?: A Critical Engagement with the Debate Generated by Alick Macheso’s Use of Manhood to Treat Nhova (Sunken Fontanelle)

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Charles Tembo ◽  
Allan Maganga ◽  
Peterson Dewah
Keyword(s):  
Ethical Issues ◽  
General Tendency ◽  
Ethical Values ◽  
Ethical Considerations ◽  
Lower Back ◽  
African Ethics ◽  
Cultural Grounding ◽  
The Face ◽  
Left And Right ◽  
Points Of View

 This article presents various points of view regarding the treatment of sunken fontanelle by various communities as ignited by the controversial practice of kutara(a practice that involves the father of a child sliding his penis from the lower part of the left and right cheeks to the top of the head, as well as from the lower part of the face to the top of the head, and from the lower back part of the head to the top). The story of Alick Macheso’s use of his manhood to treat nhova (sunken fontanelle) opened a Pandora’s box. The story not only attracted the attention of critics from diverse cultural and ethical backgrounds, but revealed multi-ethnic positions. That is, reactions were steeped in a multiplicity of intellectual, religious and even cultural grounding. Reactions ranged from accusations of backwardness and absurdity, through to medical and Christian orientations toward the treatment of nhova. The overarching idea is that there is a general tendency to dismiss the age-old practice of kutara,coupled with an uncritical celebration of certain positions. The debate that ensued following publication of the story seemed to revolve around ethical considerations. The school of thought that dismisses kutara with disdain regards it as unethical and unimaginable in the present-day world—it is redolent with insinuations of absurdity on the part of those that live and celebrate it. We contend that the raging debate that followed the publication of the story can best be conceptualised within the context of African ethics. We note that kutara has relevance to the spirituality, ethical values, privacy, and protection of children’s rights, among other ethical issues. It is hoped that the article will stir further debate and encourage more research among information practitioners, scholars and researchers into the ethical issues surrounding the treatment of sunken fontanelle in various African communities. It argues for an Afrocentric conceptualisation of phenomena in order to contribute to debates on the renaissance of African cultures, and stresses that it is imperative to harness the life-furthering age-old traditions in African ontological existence.

Designing a CRM Framework for online & offline sports footwear retailers

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Rodrigo Cueva ◽  
Guillem Rufian ◽  
Maria Gabriela Valdes
Keyword(s):  
Environmental Changes ◽  
Customer Relationship ◽  
Business Strategies ◽  
Economic Sectors ◽  
Running Shoes ◽  
Brick And Mortar ◽  
Key Factor ◽  
On Line ◽  
The Impact

The use of Customer Relationship Managers to foster customers loyalty has become one of the most common business strategies in the past years.  However, CRM solutions do not fill the abundance of happily ever-after relationships that business needs, and each client’s perception is different in the buying process.  Therefore, the experience must be precise, in order to extend the loyalty period of a customer as much as possible. One of the economic sectors in which CRM’s have improved this experience is retailing, where the personalized attention to the customer is a key factor.  However, brick and mortar experiences are not enough to be aware in how environmental changes could affect the industry trends in the long term.  A base unified theoretical framework must be taken into consideration, in order to develop an adaptable model for constructing or implementing CRMs into companies. Thanks to this approximation, the information is complemented, and the outcome will increment the quality in any Marketing/Sales initiative. The goal of this article is to explore the different factors grouped by three main domains within the impact of service quality, from a consumer’s perspective, in both on-line and off-line retailing sector.  Secondly, we plan to go a step further and extract base guidelines about previous analysis for designing CRM’s solutions focused on the loyalty of the customers for a specific retailing sector and its product: Sports Running Shoes.

The Many Faces of Socioeconomic Change

2017 ◽  
Author(s):  
John Toye
Keyword(s):  
Socioeconomic Development ◽  
Adam Smith ◽  
First Century ◽  
Social Progress ◽  
Long Time ◽  
The Face ◽  
Scientific Expertise ◽  
The Many ◽  
Century Development

This book provides a survey of different ways in which economic sociocultural and political aspects of human progress have been studied since the time of Adam Smith. Inevitably, over such a long time span, it has been necessary to concentrate on highlighting the most significant contributions, rather than attempting an exhaustive treatment. The aim has been to bring into focus an outline of the main long-term changes in the way that socioeconomic development has been envisaged. The argument presented is that the idea of socioeconomic development emerged with the creation of grand evolutionary sequences of social progress that were the products of Enlightenment and mid-Victorian thinkers. By the middle of the twentieth century, when interest in the accelerating development gave the topic a new impetus, its scope narrowed to a set of economically based strategies. After 1960, however, faith in such strategies began to wane, in the face of indifferent results and general faltering of confidence in economists’ boasts of scientific expertise. In the twenty-first century, development research is being pursued using a research method that generates disconnected results. As a result, it seems unlikely that any grand narrative will be created in the future and that neo-liberalism will be the last of this particular kind of socioeconomic theory.

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