Safety and Immunogenicity of a Plant-Produced Recombinant Hemagglutinin-Based Influenza Vaccine (HAI-05) Derived from A/Indonesia/05/2005 (H5N1) Influenza Virus: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study in Healthy Adults

Jessica Chichester; R. Jones; Brian Green; Mark Stow; Fudu Miao; George Moonsammy; Stephen Streatfield; Vidadi Yusibov

doi:10.3390/v4113227

Safety and Immunogenicity of a Plant-Produced Recombinant Hemagglutinin-Based Influenza Vaccine (HAI-05) Derived from A/Indonesia/05/2005 (H5N1) Influenza Virus: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study in Healthy Adults

Viruses ◽

10.3390/v4113227 ◽

2012 ◽

Vol 4 (11) ◽

pp. 3227-3244 ◽

Cited By ~ 48

Author(s):

Jessica Chichester ◽

R. Jones ◽

Brian Green ◽

Mark Stow ◽

Fudu Miao ◽

...

Keyword(s):

Influenza Virus ◽

Influenza Vaccine ◽

Dose Escalation ◽

Phase 1 ◽

H5n1 Influenza Virus ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

H5n1 Influenza ◽

Recombinant Hemagglutinin

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Results of a Phase 1, Double-Blind, Placebo-Controlled, Dose-Escalation Study of the Safety, Tolerability, and Pharmacokinetics of ISIS 333611 Administered Intrathecally to Patients with Familial ALS Due to SOD1 Gene Mutations (S25.001)

Neurology ◽

10.1212/wnl.78.1_meetingabstracts.s25.001 ◽

2012 ◽

Vol 78 (Meeting Abstracts 1) ◽

pp. S25.001-S25.001

Author(s):

T. Miller ◽

R. Smith ◽

A. Pestronk ◽

W. David ◽

J. Rothstein ◽

...

Keyword(s):

Dose Escalation ◽

Phase 1 ◽

Gene Mutations ◽

Sod1 Gene ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

Familial Als

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LBP-25-a phase 1 clinical trial of therapeutic vaccine t101 in chronic hepatitis b (chb) patients: a randomized, double-blind, placebo-controlled, single and multiple injections, dose escalation study

Journal of Hepatology ◽

10.1016/s0618-8278(19)30271-3 ◽

2019 ◽

Vol 70 (1) ◽

pp. e153-e154 ◽

Cited By ~ 2

Author(s):

Yue Hu ◽

Xiaomin WANG ◽

zhiming wang ◽

dong gao ◽

lan zhang ◽

...

Keyword(s):

Clinical Trial ◽

Chronic Hepatitis ◽

Hepatitis B ◽

Dose Escalation ◽

Phase 1 ◽

Therapeutic Vaccine ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 1 Clinical Trial

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Faculty Opinions recommendation of A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13409136.14780164 ◽

2011 ◽

Author(s):

John Laffey ◽

Mairead Hayes

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Dose Escalation ◽

Human Mesenchymal Stem Cells ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

Adult Human

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A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction

Yearbook of Cardiology ◽

10.1016/s0145-4145(10)79814-2 ◽

2010 ◽

Vol 2010 ◽

pp. 389-391 ◽

Cited By ~ 3

Author(s):

B.J. Gersh

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Dose Escalation ◽

Human Mesenchymal Stem Cells ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

Adult Human

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First-In-Human, Double-Blind, Placebo-Controlled, Randomized, Dose-Escalation Study of BG00010, a Glial Cell Line-Derived Neurotrophic Factor Family Member, in Subjects with Unilateral Sciatica

PLoS ONE ◽

10.1371/journal.pone.0125034 ◽

2015 ◽

Vol 10 (5) ◽

pp. e0125034 ◽

Cited By ~ 16

Author(s):

Paul E. Rolan ◽

Gilmore O’Neill ◽

Eve Versage ◽

Jitesh Rana ◽

Yongqiang Tang ◽

...

Keyword(s):

Family Member ◽

Cell Line ◽

Glial Cell ◽

Dose Escalation ◽

Neurotrophic Factor ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo

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Safety and Pharmacokinetics of the Oral TYK2 Inhibitor PF‐06826647: A Phase I, Randomized, Double‐Blind, Placebo‐Controlled, Dose‐Escalation Study

Clinical and Translational Science ◽

10.1111/cts.12929 ◽

2020 ◽

Cited By ~ 1

Author(s):

Ravi Shankar P. Singh ◽

Vivek Pradhan ◽

Erika S. Roberts ◽

Matthew Scaramozza ◽

Elizabeth Kieras ◽

...

Keyword(s):

Phase I ◽

Dose Escalation ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo

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Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: a randomised, double-blind, placebo-controlled, phase 1 study

The Lancet Infectious Diseases ◽

10.1016/s1473-3099(12)70345-6 ◽

2013 ◽

Vol 13 (3) ◽

pp. 238-250 ◽

Cited By ~ 96

Author(s):

Marc Gurwith ◽

Michael Lock ◽

Eve M Taylor ◽

Glenn Ishioka ◽

Jeff Alexander ◽

...

Keyword(s):

Influenza A ◽

Phase 1 ◽

Phase 1 Study ◽

Double Blind ◽

Adenovirus Serotype ◽

Double Blind Placebo ◽

Vector Vaccine ◽

H5n1 Influenza

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Safety of the muscarinic receptor-antagonist (R,R)-penehyclidine fumarate in healthy subjects: A phase 1 randomized, double-blind, single-dose escalation study

International Journal of Clinical Pharmacology and Therapeutics ◽

10.5414/cp203535 ◽

2020 ◽

Vol 58 (03) ◽

pp. 155-165

Author(s):

Chengxiao Fu ◽

Xingfei Zhang ◽

Qi Pei ◽

Chengxian Guo ◽

Xiaoyan Yang ◽

...

Keyword(s):

Single Dose ◽

Receptor Antagonist ◽

Muscarinic Receptor ◽

Dose Escalation ◽

Healthy Subjects ◽

Phase 1 ◽

Dose Escalation Study ◽

Double Blind ◽

Muscarinic Receptor Antagonist

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Erratum: A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients

Molecular Psychiatry ◽

10.1038/mp.2016.140 ◽

2016 ◽

Vol 21 (10) ◽

pp. 1483-1484 ◽

Cited By ~ 5

Author(s):

M Fava ◽

K Johe ◽

L Ereshefsky ◽

L G Gertsik ◽

B A English ◽

...

Keyword(s):

Dose Escalation ◽

Multiple Dose ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

Depressed Patients ◽

Phase 1B

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Neuraminidase-Inhibiting Antibody Is a Correlate of Cross-Protection against Lethal H5N1 Influenza Virus in Ferrets Immunized with Seasonal Influenza Vaccine

Journal of Virology ◽

10.1128/jvi.02434-12 ◽

2013 ◽

Vol 87 (6) ◽

pp. 3053-3061 ◽

Cited By ~ 59

Author(s):

S. Rockman ◽

L. E. Brown ◽

I. G. Barr ◽

B. Gilbertson ◽

S. Lowther ◽

...

Keyword(s):

Influenza Virus ◽

Influenza Vaccine ◽

Seasonal Influenza ◽

Cross Protection ◽

H5n1 Influenza Virus ◽

Seasonal Influenza Vaccine ◽

H5n1 Influenza

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