scholarly journals Update on the Transmission of Zika Virus Through Breast Milk and Breastfeeding: A Systematic Review of the Evidence

Viruses ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 123
Author(s):  
Elizabeth Centeno-Tablante ◽  
Melisa Medina-Rivera ◽  
Julia L. Finkelstein ◽  
Heather S. Herman ◽  
Pura Rayco-Solon ◽  
...  
Keyword(s):  
Breast Milk ◽  
Zika Virus ◽  
Mother To Child Transmission ◽  
Inclusion Criteria ◽  
Rt Pcr ◽  
Child Transmission ◽  
Zikv Infection ◽  
Milk Samples ◽  
Clinical Complications ◽  
Mother To Child

We systematically searched regional and international databases and screened 1658 non-duplicate records describing women with suspected or confirmed ZIKV infection, intending to breastfeed or give breast milk to an infant to examine the potential of mother-to-child transmission of Zika virus (ZIKV) through breast milk or breastfeeding-related practices. Fourteen studies met our inclusion criteria and inform this analysis. These studies reported on 97 mother–children pairs who provided breast milk for ZIKV assessment. Seventeen breast milk samples from different women were found positive for ZIKV via RT-PCR, and ZIKV replication was found in cell cultures from five out of seven breast milk samples from different women. Only three out of six infants who had ZIKV infection were breastfed, no evidence of clinical complications was found to be associated with ZIKV RNA in breast milk. This review updates our previous report by including 12 new articles, in which we found no evidence of ZIKV mother-to-child transmission through breast milk intake or breastfeeding. As the certainty of the present evidence is low, additional studies are still warranted to determine if ZIKV can be transmitted through breastfeeding.

scholarly journals Update on the Transmission of Zika Virus Through Breast Milk and Breastfeeding: A Systematic Review of the Evidence

2020 ◽  
Author(s):  
Elizabeth Centeno-Tablante ◽  
Melisa Medina-Rivera ◽  
Julia L Finkelstein ◽  
Heather Herman ◽  
Pura Rayco-Solon ◽  
...  
Keyword(s):  
Breast Milk ◽  
Zika Virus ◽  
Mother To Child Transmission ◽  
Inclusion Criteria ◽  
Child Transmission ◽  
Zikv Infection ◽  
Milk Samples ◽  
Clinical Complications ◽  
Breastfeeding Practices ◽  
Mother To Child

To gain new insights into the potential of mother-to-child transmission of Zika virus (ZIKV) through breast milk or breastfeeding practices, we systematically searched regional and international databases and screened 1,658 non-duplicate records describing women with suspected or confirmed ZIKV infection, intending to breastfeed or give breast milk to an infant. Fourteen studies met our inclusion criteria and inform this analysis. These studies reported on 97 mother-children pairs who provided breast milk for ZIKV assessment. Seventeen breast milk samples from different women were found positive for ZIKV via RT-PCR, and ZIKV replication was found in cell cultures from five out of seven breast milk samples from different women. Only three out of six infants who had ZIKV infection were breastfed, no evidence of clinical complications were found to be associated with ZIKV RNA in breast milk. This review updates our previous report by synthesizing the evidence from 12 new articles and we find no evidence of mother-to-child transmission through breast milk intake or breastfeeding. As the certainty of the present evidence is low, additional studies are still warranted to completely understand any potential of transmission of ZIKV through breastfeeding.

scholarly journals Evidence for Mother-to-Child Transmission of Zika Virus Through Breast Milk

2017 ◽  
Vol 66 (7) ◽  
pp. 1120-1121 ◽  
Author(s):  
Gabriela M Blohm ◽  
John A Lednicky ◽  
Marilianna Márquez ◽  
Sarah K White ◽  
Julia C Loeb ◽  
...  
Keyword(s):  
Breast Milk ◽  
Zika Virus ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Mother To Child

scholarly journals HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission

AIDS ◽  
2008 ◽  
Vol 22 (12) ◽  
pp. 1475-1485 ◽  
Author(s):  
Dara A Lehman ◽  
Michael H Chung ◽  
Grace C John-Stewart ◽  
Barbra A Richardson ◽  
James Kiarie ◽  
...  
Keyword(s):  
Breast Milk ◽  
Antiretroviral Treatment ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Mother To Child ◽  
Hiv 1

scholarly journals Presence of Ebola Virus in Breast Milk and Its Risk of Transmission to Breastfeeding Infants: Synthesis of Evidence

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1036-1036
Author(s):  
Melisa Medina-Rivera ◽  
Elizabeth Centeno-Tablante ◽  
Julia Finkelstein ◽  
Juan Pablo Peña-Rosas ◽  
Maria Nieves Garcia-Casal ◽  
...  
Keyword(s):  
Breast Milk ◽  
Ebola Virus ◽  
Case Reports ◽  
Data Extraction ◽  
Inclusion Criteria ◽  
Rt Pcr ◽  
Breastfed Infants ◽  
Milk Samples ◽  
Funding Sources ◽  
Ebov Infection

Abstract Objectives This study aimed to synthesize evidence related to the presence in and transmission of the Ebola virus (EBOV) through breast milk to help inform global guidelines on infant feeding. Methods We conducted a comprehensive systematic search in international and regional databases to identify original studies describing women with suspected or confirmed EBOV infection intending to breastfeed or give breast milk to an infant. Studies documenting any breastfeeding woman who has been vaccinated or is suspected or confirmed of viral infection at any time during or after pregnancy were identified. Records were independently screened by two authors and after duplicate records were removed, studies that met the inclusion criteria were selected for data extraction. Results From a total of 24,473 non-duplicate studies, we found six case reports that included seven breastfeeding mothers with suspected or confirmed EBOV infection and their eight children (one mother with twins). EBOV was detected via RT-PCR and/or by culture in five out of six breast milk samples that were collected from the mothers. Five out of the seven breastfed infants were found positive for EBOV infection and all of the identified cases led to death. Conclusions Ebola virus was detected in 5 out of 6 breast milk samples analyzed. Since the virus has also been detected in tears, saliva, and sweat, it is not possible to conclude with certainty that the transmission was through breast milk. Prospective studies are needed in order to define the safety of feeding infants with breast milk from mothers infected with EBOV. Funding Sources Department of Nutrition and Food Safety, WHO.

scholarly journals Provirus Load in Breast Milk and Risk of Mother‐to‐Child Transmission of Human T Lymphotropic Virus Type I

2004 ◽  
Vol 190 (7) ◽  
pp. 1275-1278 ◽  
Author(s):  
Hong‐Chuan Li ◽  
Robert J. Biggar ◽  
Wendell J. Miley ◽  
Elizabeth M. Maloney ◽  
Beverley Cranston ◽  
...  
Keyword(s):  
Breast Milk ◽  
Virus Type ◽  
Type I ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
T Lymphotropic Virus ◽  
Provirus Load ◽  
Mother To Child

Acceptability of Heat Treating Breast Milk to Prevent Mother-to-Child Transmission of Human Immunodeficiency Virus in Zimbabwe: A Qualitative Study

2006 ◽  
Vol 22 (1) ◽  
pp. 48-60 ◽  
Author(s):  
Kiersten A. Israel-Ballard ◽  
M. Catherine Maternowska ◽  
Barbara F. Abrams ◽  
Pamela Morrison ◽  
Livona Chitibura ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Breast Milk ◽  
Qualitative Study ◽  
Heat Treating ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Immunodeficiency Virus ◽  
Mother To Child

Interventions to decrease the risk of mother-to-child transmission of HIV-1 through breast milk

2009 ◽  
Author(s):  
Maya Tholandi ◽  
David Wilkinson ◽  
Francois Dabis ◽  
Gail E Kennedy ◽  
Banyana C Madi ◽  
...  
Keyword(s):  
Breast Milk ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Mother To Child ◽  
Hiv 1
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