scholarly journals What’s New with Flu? An Overview

Viruses ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 433 ◽  
Author(s):  
Seema S. Lakdawala ◽  
Christopher B. Brooke

One hundred years have passed since the 1918 H1N1 pandemic, and influenza viruses continue to pose an enormous and unpredictable global public health threat [...]

Vaccine ◽  
2020 ◽  
Vol 38 (24) ◽  
pp. 3989-3994 ◽  
Author(s):  
Marc Girard ◽  
Christopher B. Nelson ◽  
Valentina Picot ◽  
Duane J. Gubler

Author(s):  
Elizabeth M Batty ◽  
Theerarat Kochakarn ◽  
Bhakbhoom Panthan ◽  
Krittikorn Kümpornsin ◽  
Poramate Jiaranai ◽  
...  

AbstractCoronavirus Disease 2019 (COVID-19) is a global public health threat. Genomic surveillance of SARS-CoV-2 was implemented during March 2020 at a major diagnostic hub in Bangkok, Thailand. Several virus lineages supposedly originated in many countries were found, and a Thai-specific lineage, designated A/Thai-1, has expanded to be predominant in Thailand. A virus sample in the SARS-CoV-2 A/Thai-1 lineage contains a frame-shift deletion at ORF7a, encoding a putative host antagonizing factor of the virus.


2020 ◽  
Author(s):  
Huajun Bai ◽  
Xiaolong Cai ◽  
Xiaoyan Zhang

The outbreak of COVID-19, caused by 2019 novel coronavirus (2019-nCoV), has been a global public health threat and caught the worldwide concern. Scientists throughout the world are sparing all efforts to explore strategies for the determination of the 2019-nCoV virus and diagnosis of COVID-19 rapidly. Several assays are developed for COVID-19 test , including RT-PCR, coronavirus antigens-based immunoassays, and CRISPR-based strategies (Cas13a or Cas12a), etc. Different assays have their advantages and drawbacks, and people should choose the most suitable assay according to their demands. Here, we make a brief introduction about these assays and give a simple overview of them, hoping to help doctors and researchers to select the most suitable assay for the Coronavirus Disease 2019 test (COVID-19 test) .


2007 ◽  
Vol 18 (5) ◽  
pp. 289-291 ◽  
Author(s):  
Paul E Alexander ◽  
Prithwish De

Resistance to anti-tuberculosis (TB) drugs continues to present a major challenge to global public health. Resistance usually develops due to inadequate TB management, including improper use of medications, improper treatment regimens and failure to complete the treatment course. This may be due to an erratic supply or a lack of access to treatment, as well as to patient noncompliance. However, the emergence and transmission of drug-resistant TB, including the recently detected extensively drug resistant TB (XDR-TB), is driven, in part, by the synergistic relationship between TB and HIV (TB/HIV coinfection). There is evidence that persons infected with HIV are more likely to experience XDR-TB. XDR-TB is virtually untreatable with available TB medications. XDR-TB presents a grave global public health threat, particularly in high HIV prevalence settings. The present commentary discusses the current status of XDR-TB and draws attention to the urgency in addressing this problem, for both the global and Canadian public health networks. XDR-TB and the apparent XDR-TB and HIV association warrants further study.


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