scholarly journals Analysis, Simulation, and Development of a Low-Cost Fully Active-Electrode Bioimpedance Measurement Module

Technologies ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 59
Author(s):  
Christos Dimas ◽  
Vassilis Alimisis ◽  
Ioannis Georgakopoulos ◽  
Nikolaos Voudoukis ◽  
Nikolaos Uzunoglu ◽  
...  

A low-cost 1 kHz–400 kHz operating frequency fully-active electrode bioimpedance measurement module, based on Howland current source, is presented in this paper. It includes a buffered positive feedback Howland current source, implemented with operational amplifiers, as well as an AD8421 instrumentation amplifier, for the differential voltage measurements. Each active electrode module can be connected to others, assembling a wearable active electrode module array. From this array, 2 electrodes can be selected to be driven from a THS413 fully differential amplifier, activating a mirrored Howland current source. This work performs a complete circuit analysis, verified with MATLAB and SPICE simulations of the current source’s transconductance and output impedance over the frequency range between 1 kHz and 1 MHz. Resistors’ tolerances, possible mismatches, and the operational amplifiers’ non-idealities are considered in both the analysis and simulations. A comparison study between four selected operational amplifiers (ADA4622, OPA2210, AD8034, and AD8672) is additionally performed. The module is also hardware-implemented and tested in the lab for all four operational amplifiers and the transconductance is measured for load resistors of 150 Ω, 660 Ω, and 1200 Ω. Measurements showed that, using the AD8034 operational amplifier, the current source’s transconductance remains constant for frequencies up to 400 KHz for a 150 Ω load and 250 kHz for a 1200 Ω load, while lower performance is achieved with the other 3 operational amplifiers. Finally, transient simulations and measurements are performed at the AD8421 output for bipolar measurements on the 3 aforementioned load resistor values.

2019 ◽  
Vol 6 (1) ◽  
pp. 18-21
Author(s):  
F. J. Pettersen ◽  
J. O. Høgetveit

Abstract There is a need for isolated current sources for use in selected bioimpedance measurement circuits. The requirement for good isolation is particularly important in medical settings because of safety concerns. A new circuit for producing voltage-controlled current is presented. Measurements have been made on a prototype and simulations have been done on a SPICE model. The presented circuit is an H-bridge where the output devices are the output photodiodes of high-linearity optocouplers. Five operational amplifiers, four high linearity optocouplers, and passive components are used. Output current capability is ±35 μA with an output impedance that is more than 1 M Ω. It is possible to achieve bandwidths above 1 MHz for small load impedances. This circuit is well suited for medical applications thanks to the isolation in the optocouplers.


2018 ◽  
Vol 9 (1) ◽  
pp. 59-71
Author(s):  
Vinicius G Sirtoli ◽  
Kaue F Morcelles ◽  
Volney C Vincence

Abstract Bioimpedance measurement systems often use the Howland current sources to excite the biological material under study. Usually, difference or instrumentation amplifiers are used to measure the resulting voltage drop on this material. In these circuits, common mode voltage appears as artifacts in the measurement. Most researches on current sources are focused on improving the output impedance, letting other characteristics aside. In this paper, it is made a brief review on the load common mode voltage and output swing of various topologies of Howland current sources. Three circuits are proposed to reduce load common mode voltage and enhance load capability by using a fully differential amplifier as active component. These circuits are equated, simulated and implemented. The three proposed circuits were able to deliver an output current with cut-off frequency (-3dB) higher than 1 MHz for loads as big as 4.7 kΩ. The worst measured load common mode voltage was smaller than 24 mV for one of the circuits and smaller than 8 mV for the other two. Consequently, it could be obtained increases in the Common Mode Rejection Ratio (CMRR) up to 60 dB when compared to the Enhanced Howland Current Source (EHCS).


2020 ◽  
Vol 12 (3) ◽  
pp. 168-174
Author(s):  
Rashmi Sahu ◽  
Maitraiyee Konar ◽  
Sudip Kundu

Background: Sensing of biomedical signals is crucial for monitoring of various health conditions. These signals have a very low amplitude (in μV) and a small frequency range (<500 Hz). In the presence of various common-mode interferences, biomedical signals are difficult to detect. Instrumentation amplifiers (INAs) are usually preferred to detect these signals due to their high commonmode rejection ratio (CMRR). Gain accuracy and CMRR are two important parameters associated with any INA. This article, therefore, focuses on the improvement of the gain accuracy and CMRR of a low power INA topology. Objective: The objective of this article is to achieve high gain accuracy and CMRR of low power INA by having high gain operational amplifiers (Op-Amps), which are the building blocks of the INAs. Methods: For the implementation of the Op-Amps and the INAs, the Cadence Virtuoso tool was used. All the designs and implementation were realized in 0.18 μm CMOS technology. Results: Three different Op-Amp topologies namely single-stage differential Op-Amp, folded cascode Op-Amp, and multi-stage Op-Amp were implemented. Using these Op-Amp topologies separately, three Op-Amp-based INAs were realized and compared. The INA designed using the high gain multistage Op-Amp topology of low-frequency gain of 123.89 dB achieves a CMRR of 164.1 dB, with the INA’s gain accuracy as good as 99%, which is the best when compared to the other two INAs realized using the other two Op-Amp topologies implemented. Conclusion: Using very high gain Op-Amps as the building blocks of the INA improves the gain accuracy of the INA and enhances the CMRR of the INA. The three Op-Amp-based INA designed with the multi-stage Op-Amps shows state-of-the-art characteristics as its gain accuracy is 99% and CMRR is as high as 164.1 dB. The power consumed by this INA is 29.25 μW by operating on a power supply of ±0.9V. This makes this INA highly suitable for low power measurement applications.


Micromachines ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 461 ◽  
Author(s):  
Chenchen Xie ◽  
Xi Li ◽  
Houpeng Chen ◽  
Yang Li ◽  
Yuanguang Liu ◽  
...  

Multi-level cell (MLC) phase change memory (PCM) can not only effectively multiply the memory capacity while maintaining the cell area, but also has infinite potential in the application of the artificial neural network. The write and verify scheme is usually adopted to reduce the impact of device-to-device variability at the expense of a greater operation time and more power consumption. This paper proposes a novel write operation for multi-level cell phase change memory: Programmable ramp-down current pulses are utilized to program the RESET initialized memory cells to the expected resistance levels. In addition, a fully differential read circuit with an optional reference current source is employed to complete the readout operation. Eventually, a 2-bit/cell phase change memory chip is presented with a more efficient write operation of a single current pulse and a read access time of 65 ns. Some experiments are implemented to demonstrate the resistance distribution and the drift.


2020 ◽  
Vol 87 (s1) ◽  
pp. s79-s84
Author(s):  
Qummar Zaman ◽  
Senan Alraho ◽  
Andreas König

AbstractThe conventional method for testing the performance of reconfigurable sensory electronics of industry 4.0 relies on the direct measurement methods. This approach gives higher accuracy but at the price of extremely high testing cost and does not utilize the new degrees of freedom for measurement methods enabled by industry 4.0. In order to reduce the test cost and use available resources more efficiently, a primary approach, called indirect measurements or alternative testing has been proposed using a non-intrusive sensor. Its basic principle consists in using the indirect measurements, in order to estimate the sensory electronics performance parameters without measuring directly. The non-intrusive property of the proposed method offers better performance of the sensing electronics and virtually applicable to any sensing electronics. Efficiency is evaluated in terms of model accuracy by using six different classical metrics. It uses an indirect current-feedback instrumentation amplifier (InAmp) as a test vehicle to evaluate the performance parameters of the circuit. The device is implemented using CMOS 0.35 μm technology. The achieved maximum value of average expected error metrics is 0.24, and the lowest value of correlation performance metrics is 0.91, which represent an excellent efficiency of InAmp performance predictor.


2014 ◽  
Vol 945-949 ◽  
pp. 1924-1931
Author(s):  
Hai Qing Yao ◽  
Heng Cao ◽  
Fei Jiang ◽  
Bo Sun

Based on the excellent performance of Pt100, a portable low-cost precision temperature sensor has been designed, whose core chips are REF03, AD8603, AD7788 and precision resistors. Constant current source (CCS) for 4-wire Pt100 is constituted by REF03, AD8603 and precision resistors. AD7788 measures the differential signal on Pt100 and suppresses the common mode interference signal. Analysis software running on the micro control unit (MCU) filters the digital code from AD7788, and then calculates the current temperature value according to the resistance-temperature mathematical model of Pt100. Analysis and experimental results show that the temperature measurement accuracy of the sensor can reach ±1°C within the range of 0°C-650°C.


Sign in / Sign up

Export Citation Format

Share Document