scholarly journals Erratum: Mohammad Shibli Kaysar and Mohammad Ibrahim Khan A Modified Median String Algorithm for Gene Regulatory Motif Classification Symmetry 2020, 12, 8

Symmetry ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 1433
Author(s):  
Mohammad Shibli Kaysar ◽  
Mohammad Ibrahim Khan

The authors wish to make the following corrections to their paper: [...]

Symmetry ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 1363
Author(s):  
Mohammad Shibli Kaysar ◽  
Mohammad Ibrahim Khan

Consensus string is a significant feature of a deoxyribonucleic acid (DNA) sequence. The median string is one of the most popular exact algorithms to find DNA consensus. A DNA sequence is represented using the alphabet Σ= {a, c, g, t}. The algorithm generates a set of all the 4l possible motifs or l-mers from the alphabet to search a motif of length l. Out of all possible l-mers, it finds the consensus. This algorithm guarantees to return the consensus but this is NP-complete and runtime increases with the increase in l-mer size. Using transitional probability from the Markov chain, the proposed algorithm symmetrically generates four subsets of l-mers. Each of the subsets contains a few l-mers starting with a particular letter. We used these reduced sets of l-mers instead of using 4ll-mers. The experimental result shows that the proposed algorithm produces a much lower number of l-mers and takes less time to execute. In the case of l-mer of length 7, the proposed system is 48 times faster than the median string algorithm. For l-mer of size 7, the proposed algorithm produces only 2.5% l-mer in comparison with the median string algorithm. While compared with the recently proposed voting algorithm, our proposed algorithm is found to be 4.4 times faster for a longer l-mer size like 9.


2015 ◽  
Vol 8 (4) ◽  
pp. 463-476 ◽  
Author(s):  
Dennis Kostka ◽  
Tara Friedrich ◽  
Alisha K. Holloway ◽  
Katherine S. Pollard

2018 ◽  
Vol 445 ◽  
pp. 103-109 ◽  
Author(s):  
Fernando Antoneli ◽  
Martin Golubitsky ◽  
Ian Stewart

Gene ◽  
1995 ◽  
Vol 154 (1) ◽  
pp. 131-132 ◽  
Author(s):  
JoséL. Vizmanos ◽  
Javier I. Jauregui ◽  
Arturo Gullón ◽  
Carlos J. González ◽  
Maria P. Civeira ◽  
...  

Author(s):  
Leonardo Mariño-Ramírez ◽  
Kannan Tharakaraman ◽  
John L. Spouge ◽  
David Landsman

2020 ◽  
Vol 48 (3) ◽  
pp. 1019-1034 ◽  
Author(s):  
Rachel M. Woodhouse ◽  
Alyson Ashe

Gene regulatory information can be inherited between generations in a phenomenon termed transgenerational epigenetic inheritance (TEI). While examples of TEI in many animals accumulate, the nematode Caenorhabditis elegans has proven particularly useful in investigating the underlying molecular mechanisms of this phenomenon. In C. elegans and other animals, the modification of histone proteins has emerged as a potential carrier and effector of transgenerational epigenetic information. In this review, we explore the contribution of histone modifications to TEI in C. elegans. We describe the role of repressive histone marks, histone methyltransferases, and associated chromatin factors in heritable gene silencing, and discuss recent developments and unanswered questions in how these factors integrate with other known TEI mechanisms. We also review the transgenerational effects of the manipulation of histone modifications on germline health and longevity.


2009 ◽  
Vol 138 (1) ◽  
pp. 172-185
Author(s):  
Ben Emery ◽  
Dritan Agalliu ◽  
John D. Cahoy ◽  
Trent A. Watkins ◽  
Jason C. Dugas ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2061-P
Author(s):  
NATHAN LAWLOR ◽  
ROMY KURSAWE ◽  
MICHAEL L. STITZEL

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