scholarly journals Ionic Systems and Nanomaterials as Antiseptic and Disinfectant Agents for Surface Applications: A Review

Surfaces ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. 169-190
Author(s):  
Francisco Faísca ◽  
Luis Filipe ◽  
Zeljko Petrovski ◽  
Miguel M. Santos ◽  
Sandra Gago ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Ionic Liquids ◽  
Broad Spectrum ◽  
Mode Of Action ◽  
Test Method ◽  
Organic Load ◽  
Ionic Surfactants ◽  
Chemical Agents ◽  
Ionic Systems ◽  
Active Chemical

Antiseptics and disinfectants are extensively used for a variety of topical and hard-surface applications. A wide variety of biocides as active chemical agents is found in these products, including alcohols, phenols, iodine, and chlorine. Many of these active agents demonstrate broad-spectrum antimicrobial activity; however, the mode of action of these agents is not well-documented. This review is focused on several examples of ionic systems based on ionic surfactants and ionic liquids as well as nanomaterials and nanoparticles acting as antiseptics and disinfectants for surfaces. It is important to note that many of these biocides may be used singly or in combination in a variety of products, which vary considerably in activity against microorganisms. Antimicrobial activity can be influenced by several factors such as formulation effects, presence of an organic load, synergy, temperature, dilution, and test method. The most promissory compounds based on ionic systems and nanomaterials published in mainly the last decade is chronologically reported in this review.

scholarly journals Antiseptics and Disinfectants: Activity, Action, and Resistance

1999 ◽  
Vol 12 (1) ◽  
pp. 147-179 ◽  
Author(s):  
Gerald McDonnell ◽  
A. Denver Russell
Keyword(s):  
Health Care ◽  
Antimicrobial Activity ◽  
Antibiotic Resistance ◽  
Broad Spectrum ◽  
Mode Of Action ◽  
Clinical Implications ◽  
Microbial Resistance ◽  
Health Care Settings ◽  
Chemical Agents ◽  
Active Chemical

SUMMARY Antiseptics and disinfectants are extensively used in hospitals and other health care settings for a variety of topical and hard-surface applications. A wide variety of active chemical agents (biocides) are found in these products, many of which have been used for hundreds of years, including alcohols, phenols, iodine, and chlorine. Most of these active agents demonstrate broad-spectrum antimicrobial activity; however, little is known about the mode of action of these agents in comparison to antibiotics. This review considers what is known about the mode of action and spectrum of activity of antiseptics and disinfectants. The widespread use of these products has prompted some speculation on the development of microbial resistance, in particular whether antibiotic resistance is induced by antiseptics or disinfectants. Known mechanisms of microbial resistance (both intrinsic and acquired) to biocides are reviewed, with emphasis on the clinical implications of these reports.

The Study of Bacillus Subtils Antimicrobial Activity on Some of the Pathological Isolates

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Hussein A Kadhum ◽  
Thualfakar H Hasan2
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Bacterial Growth ◽  
Broad Spectrum ◽  
Inhibitory Activity ◽  
Bacterial Pathogens ◽  
Inhibitory Ability ◽  
Selection Of

The study involved the selection of two isolates from Bacillus subtilis to investigate their inhibitory activity against some bacterial pathogens. B sub-bacteria were found to have a broad spectrum against test bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. They were about 23-30 mm and less against Klebsiella sp. The sensitivity of some antibodies was tested on the test samples. The results showed that the inhibitory ability of bacterial growth in the test samples using B. subtilis extract was more effective than the antibiotics used.

scholarly journals Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity

RSC Advances ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 2673-2702 ◽  
Author(s):  
Anupam Roy ◽  
Onur Bulut ◽  
Sudip Some ◽  
Amit Kumar Mandal ◽  
M. Deniz Yilmaz
Keyword(s):  
Antimicrobial Activity ◽  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Mode Of Action ◽  
Antimicrobial Agents ◽  
Recent Advances

In this review, we discuss the recent advances in green synthesis of silver nanoparticles, their application as antimicrobial agents and mechanism of antimicrobial mode of action.

scholarly journals Decoupling manufacturing from application in additive manufactured antimicrobial materials

2021 ◽  
Author(s):  
Dominic James Wales ◽  
Sara Miralles-Comins ◽  
Isabel Franco Castillo ◽  
Jamie Cameron ◽  
Qun Cao ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Silver Nanoparticles ◽  
Ionic Liquids ◽  
Polymeric Ionic Liquids ◽  
Antimicrobial Materials

3D printable materials based on polymeric ionic liquids (PILs) capable of controlling the synthesis and stabilization of silver nanoparticles (AgNPs) and their synergistic antimicrobial activity are reported. The interaction of...

scholarly journals Aggregation Behavior and Antimicrobial Activity of Ester-Functionalized Imidazolium- and Pyridinium-Based Ionic Liquids in Aqueous Solution

Langmuir ◽  
2013 ◽  
Vol 29 (8) ◽  
pp. 2536-2545 ◽  
Author(s):  
M. Teresa Garcia ◽  
Isabel Ribosa ◽  
Lourdes Perez ◽  
Angeles Manresa ◽  
Francesc Comelles
Keyword(s):  
Aqueous Solution ◽  
Antimicrobial Activity ◽  
Ionic Liquids ◽  
Aggregation Behavior

scholarly journals Insights into the Mode of Action of Chitosan as an Antibacterial Compound

2008 ◽  
Vol 74 (12) ◽  
pp. 3764-3773 ◽  
Author(s):  
Dina Raafat ◽  
Kristine von Bargen ◽  
Albert Haas ◽  
Hans-Georg Sahl
Keyword(s):  
Antimicrobial Activity ◽  
Cell Wall ◽  
Cell Membrane ◽  
Mode Of Action ◽  
Membrane Lipids ◽  
Expression Profiles ◽  
Transcriptional Response ◽  
Response Analysis ◽  
Sequence Of Events ◽  
Wide Range

ABSTRACT Chitosan is a polysaccharide biopolymer that combines a unique set of versatile physicochemical and biological characteristics which allow for a wide range of applications. Although its antimicrobial activity is well documented, its mode of action has hitherto remained only vaguely defined. In this work we investigated the antimicrobial mode of action of chitosan using a combination of approaches, including in vitro assays, killing kinetics, cellular leakage measurements, membrane potential estimations, and electron microscopy, in addition to transcriptional response analysis. Chitosan, whose antimicrobial activity was influenced by several factors, exhibited a dose-dependent growth-inhibitory effect. A simultaneous permeabilization of the cell membrane to small cellular components, coupled to a significant membrane depolarization, was detected. A concomitant interference with cell wall biosynthesis was not observed. Chitosan treatment of Staphylococcus simulans 22 cells did not give rise to cell wall lysis; the cell membrane also remained intact. Analysis of transcriptional response data revealed that chitosan treatment leads to multiple changes in the expression profiles of Staphylococcus aureus SG511 genes involved in the regulation of stress and autolysis, as well as genes associated with energy metabolism. Finally, a possible mechanism for chitosan's activity is postulated. Although we contend that there might not be a single classical target that would explain chitosan's antimicrobial action, we speculate that binding of chitosan to teichoic acids, coupled with a potential extraction of membrane lipids (predominantly lipoteichoic acid) results in a sequence of events, ultimately leading to bacterial death.

scholarly journals Antimicrobial activity of Paenibacillus peoriae strain NRRL BD-62 against a broad spectrum of phytopathogenic bacteria and fungi

2003 ◽  
Vol 95 (5) ◽  
pp. 1143-1151 ◽  
Author(s):  
I. Weid ◽  
D.S. Alviano ◽  
A.L.S. Santos ◽  
R.M.A. Soares ◽  
C.S. Alviano ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Broad Spectrum ◽  
Phytopathogenic Bacteria ◽  
Bacteria And Fungi

scholarly journals Draft Genome Sequence of Brevibacillus brevis DZQ7, a Plant Growth-Promoting Rhizobacterium with Broad-Spectrum Antimicrobial Activity

2015 ◽  
Vol 3 (4) ◽  
Author(s):  
Qihui Hou ◽  
Chengqiang Wang ◽  
Xiaoyang Hou ◽  
Zhilin Xia ◽  
Jiangping Ye ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Plant Growth ◽  
Genome Sequence ◽  
Broad Spectrum ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Functional Genes ◽  
Plant Growth Promoting ◽  
Brevibacillus Brevis ◽  
Growth Promoting

Brevibacillus brevis DZQ7 is a plant growth-promoting rhizobacterium (PGPR) isolated from tobacco rhizosphere. Here, we report the draft genome sequence of B. brevis DZQ7. Several functional genes related to antimicrobial activity were identified in the genome.

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