scholarly journals Development of a DNA Sensor Based on Alkanethiol Self- Assembled Monolayer-Modified Electrodes

Sensors ◽  
2005 ◽  
Vol 5 (6) ◽  
pp. 344-363 ◽  
Author(s):  
Óscar Loaiza ◽  
Susana Campuzano ◽  
María López-Berlanga ◽  
María Pedrero ◽  
José Pingarrón
Keyword(s):  
Modified Electrodes ◽  
Dna Sensor ◽  
Self Assembled Monolayer ◽  
Self Assembled

Charge Transfer Property of Self-Assembled Viologen Derivative by Electrochemical Quartz Crystal Microbalance Response

2006 ◽  
Vol 6 (11) ◽  
pp. 3657-3660 ◽  
Author(s):  
Dong-Yun Lee ◽  
A. K. M. Kafi ◽  
Sang-Hyun Park ◽  
Young-Soo Kwon
Keyword(s):  
Charge Transfer ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Modified Electrodes ◽  
Electrochemical Quartz Crystal Microbalance ◽  
Frequency Change ◽  
Self Assembled Monolayer ◽  
Transfer Property ◽  
Redox Peak ◽  
Self Assembled

Viologen modified electrodes have been extensively investigated with quartz crystal microbalance (QCM), which has been known as a nano-gram order mass detector, because of their highly reversible electrochemical properties, especially the first reduction-oxidation cycle of V2+ ↔ V•+. The purpose of this work was to study the charge transfer characteristics of self-assembled monolayer (SAM) by changing electrolyte solutions where the cations and anions are different. The redox peak currents were nearly equal charges during redox processes and showed an excellent linear interrelation between the scan rates and second redox peak currents. The charge transfer of self-assembled viologen monolayer was determined by the mass change during the cyclic voltammetry (CV). The total frequency change was about 17.8 Hz, 19.6 Hz, 9.5 Hz, and 8.4 Hz. From this data, we could know the transferred mass was about 19.0 ng, 20.9 ng, 10.2 ng, and 9.0 ng. Finally, the electrochemical quartz crystal microbalance (EQCM) has been employed to monitor the electrochemically induced adsorption of self-assembled monolayer.

Development of amperometric biosensors using thiolated tetrathiafulvalene-derivatised self-assembled monolayer modified electrodes

2008 ◽  
Vol 134 (2) ◽  
pp. 974-980 ◽  
Author(s):  
Susana Campuzano ◽  
Vanessa Escamilla-Gómez ◽  
M. Ángeles Herranz ◽  
María Pedrero ◽  
José M. Pingarrón
Keyword(s):  
Modified Electrodes ◽  
Amperometric Biosensors ◽  
Self Assembled Monolayer ◽  
Self Assembled

An electro-active system of immuno-assay (EASI assay) utilising self assembled monolayer modified electrodes

2001 ◽  
Vol 16 (9-12) ◽  
pp. 875-885 ◽  
Author(s):  
Robert Porter ◽  
Paul van der Logt ◽  
Steven Howell ◽  
Marika Kyröläinen-Reay ◽  
Andy Badley
Keyword(s):  
Modified Electrodes ◽  
Active System ◽  
Self Assembled Monolayer ◽  
Self Assembled ◽  
Immuno Assay

Formation of Efficient Electron Transfer Pathways by Adsorbing Gold Nanoparticles to Self-Assembled Monolayer Modified Electrodes

Langmuir ◽  
2009 ◽  
Vol 25 (18) ◽  
pp. 11121-11128 ◽  
Author(s):  
Jarred B. Shein ◽  
Leo M. H. Lai ◽  
Paul K. Eggers ◽  
Michael N. Paddon-Row ◽  
J. Justin Gooding
Keyword(s):  
Gold Nanoparticles ◽  
Electron Transfer ◽  
Modified Electrodes ◽  
Self Assembled Monolayer ◽  
Electron Transfer Pathways ◽  
Self Assembled

scholarly journals Evaluation of Polytyramine Film and 6-Mercaptohexanol Self-Assembled Monolayers as the Immobilization Layers for a Capacitive DNA Sensor Chip: A Comparison

Sensors ◽  
2021 ◽  
Vol 21 (23) ◽  
pp. 8149
Author(s):  
Ally Mahadhy ◽  
Bo Mattiasson ◽  
Eva StåhlWernersson ◽  
Martin Hedström
Keyword(s):  
Atomic Force Microscopy ◽  
Cyclic Voltammetry ◽  
Sensor Chip ◽  
Dna Sensor ◽  
Self Assembled Monolayer ◽  
Single Stranded Dna ◽  
Force Microscopy ◽  
Atomic Force ◽  
Self Assembled ◽  
Modified Sensor

The performance of a biosensor is associated with the properties of an immobilization layer on a sensor chip. In this study, gold sensor chips were modified with two different immobilization layers, polytyramine film and 6-mercaptohexanol self-assembled monolayer. The physical, electrochemical and analytical properties of polytyramine film and mercaptohexanol self-assembled monolayer modified gold sensor chips were studied and compared. The study was conducted using atomic force microscopy, cyclic voltammetry and a capacitive DNA-sensor system (CapSenze™ Biosystem). The results obtained by atomic force microscopy and cyclic voltammetry indicate that polytyramine film on the sensor chip surface possesses better insulating properties and provides more spaces for the immobilization of the capture probe than a mercaptohexanol self-assembled monolayer. A capacitive DNA sensor hosting a polytyramine single-stranded DNA-modified sensor chip displayed higher sensitivity and larger signal amplitude than that of a mercaptohexanol single-stranded DNA-modified sensor chip. The linearity responses for polytyramine single-stranded DNA- and mercaptohexanol single-stranded DNA-modified sensor chips were obtained at log concentration ranges, equivalent to 10−12 to 10−8 M and 10−10 to 10−8 M, with detection limits of 4.0 × 10−13 M and 7.0 × 10−11 M of target complementary single-stranded DNA, respectively. Mercaptohexanol single-stranded DNA- and polytyramine single-stranded DNA-modified sensor chips exhibited a notable selectivity at an elevated hybridization temperature of 50 °C, albeit the signal amplitudes due to the hybridization of the target complementary single-stranded DNA were reduced by almost 20% and less than 5%, respectively.

Sign in / Sign up

Export Citation Format

Share Document