scholarly journals Proof of Concept Novel Configurable Chipless RFID Strain Sensor

Sensors ◽  
2021 ◽  
Vol 21 (18) ◽  
pp. 6224
Author(s):  
Kevin Mc Gee ◽  
Prince Anandarajah ◽  
David Collins
Keyword(s):  
Real Life ◽  
Strain Sensor ◽  
The Other ◽  
Electromagnetic Response ◽  
Proof Of Concept ◽  
Strain Sensing ◽  
Substrate Type ◽  
Sensor Orientation ◽  
Chipless Rfid ◽  
Highly Sensitive

This paper contains two main areas of research: First, this work outlines a novel, highly sensitive strain sensor design that should support various levels of deformation, depending on the substrate type used. Physical implementations in this work have focused on proving its large deformation capabilities, and simulations have been used to assess its more general electromagnetic response. The other part of this paper focusses on exploring other effects that will impact the sensing of strain of resolutions below 10 με, which is a capability achieved by other aerospace-grade strain sensor technologies. These effects are limited to mechanical swelling and sensor orientation in the azimuth and elevation planes, as these appear to be unexplored and highly relevant issues to the topic of chipless RFID-based strain sensing. From this exploration, it is apparent that the effects of mechanical swelling and sensor orientation (amongst others) will need to be addressed in any real-life implementation of the sensor, requiring a strain resolution below 10 με.

Highly sensitive, durable and stretchable plastic strain sensors using sandwich structures of PEDOT:PSS and an elastomer

2018 ◽  
Vol 2 (2) ◽  
pp. 355-361 ◽  
Author(s):  
Xi Fan ◽  
Naixiang Wang ◽  
Jinzhao Wang ◽  
Bingang Xu ◽  
Feng Yan
Keyword(s):  
Plastic Strain ◽  
Sandwich Structures ◽  
Strain Sensor ◽  
High Sensitivity ◽  
Strain Sensors ◽  
Strain Sensing ◽  
Highly Sensitive

A stretchable plastic strain sensor was fabricated, showing high sensitivity and a broad strain-sensing region with good durability.

scholarly journals Development of Highly Sensitive Strain Sensor Using Area-Arrayed Graphene Nanoribbons

Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1701
Author(s):  
Ken Suzuki ◽  
Ryohei Nakagawa ◽  
Qinqiang Zhang ◽  
Hideo Miura
Keyword(s):  
Graphene Nanoribbons ◽  
Strain Sensor ◽  
Strain Sensors ◽  
Sensitive Strain ◽  
Bending Test ◽  
Gauge Factor ◽  
Four Point Bending ◽  
Current Voltage ◽  
Highly Sensitive ◽  
Current Voltage Relationship

In this study, a basic design of area-arrayed graphene nanoribbon (GNR) strain sensors was proposed to realize the next generation of strain sensors. To fabricate the area-arrayed GNRs, a top-down approach was employed, in which GNRs were cut out from a large graphene sheet using an electron beam lithography technique. GNRs with widths of 400 nm, 300 nm, 200 nm, and 50 nm were fabricated, and their current-voltage characteristics were evaluated. The current values of GNRs with widths of 200 nm and above increased linearly with increasing applied voltage, indicating that these GNRs were metallic conductors and a good ohmic junction was formed between graphene and the electrode. There were two types of GNRs with a width of 50 nm, one with a linear current–voltage relationship and the other with a nonlinear one. We evaluated the strain sensitivity of the 50 nm GNR exhibiting metallic conduction by applying a four-point bending test, and found that the gauge factor of this GNR was about 50. Thus, GNRs with a width of about 50 nm can be used to realize a highly sensitive strain sensor.

scholarly journals Chromatin Manipulation and Editing: Challenges, New Technologies and Their Use in Plants

2021 ◽  
Vol 22 (2) ◽  
pp. 512
Author(s):  
Kateryna Fal ◽  
Denisa Tomkova ◽  
Gilles Vachon ◽  
Marie-Edith Chabouté ◽  
Alexandre Berr ◽  
...  
Keyword(s):  
Cell Fate ◽  
Dna Sequence ◽  
Zinc Finger ◽  
Chromatin Structure ◽  
New Technologies ◽  
Dna Interaction ◽  
The Other ◽  
Proof Of Concept ◽  
Epigenetic Marks ◽  
Molecular Events

An ongoing challenge in functional epigenomics is to develop tools for precise manipulation of epigenetic marks. These tools would allow moving from correlation-based to causal-based findings, a necessary step to reach conclusions on mechanistic principles. In this review, we describe and discuss the advantages and limits of tools and technologies developed to impact epigenetic marks, and which could be employed to study their direct effect on nuclear and chromatin structure, on transcription, and their further genuine role in plant cell fate and development. On one hand, epigenome-wide approaches include drug inhibitors for chromatin modifiers or readers, nanobodies against histone marks or lines expressing modified histones or mutant chromatin effectors. On the other hand, locus-specific approaches consist in targeting precise regions on the chromatin, with engineered proteins able to modify epigenetic marks. Early systems use effectors in fusion with protein domains that recognize a specific DNA sequence (Zinc Finger or TALEs), while the more recent dCas9 approach operates through RNA-DNA interaction, thereby providing more flexibility and modularity for tool designs. Current developments of “second generation”, chimeric dCas9 systems, aiming at better targeting efficiency and modifier capacity have recently been tested in plants and provided promising results. Finally, recent proof-of-concept studies forecast even finer tools, such as inducible/switchable systems, that will allow temporal analyses of the molecular events that follow a change in a specific chromatin mark.

Comments on the Market Crash: Six Months After

1988 ◽  
Vol 2 (3) ◽  
pp. 45-50 ◽  
Author(s):  
Hayne Leland ◽  
Mark Rubinstein
Keyword(s):  
Standard Model ◽  
Real Life ◽  
The Other ◽  
Financial Equilibrium ◽  
The Standard Model ◽  
Trading Mechanisms

Six months after the market crash of October 1987, we are still sifting through the debris searching for its cause. Two theories of the crash sound plausible -- one based on a market panic and the other based on large trader transactions -- though there is other evidence that is difficult to reconcile. If we are to believe the market panic theory or the Brady Commission's theory that the crash was primarily caused by a few large traders, we must strongly reject the standard model. We need to build models of financial equilibrium which are more sensitive to real life trading mechanisms, which account more realistically for the formation of expectations, and which recognize that, at any one time, there is a limited pool of investors available with the ability to evaluate stocks and take appropriate action in the market.

NO, CO and H2S based pharmaceuticals in the mission of vision (eye health): a comprehensive review

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Jan Mohammad Mir ◽  
Ram Charitra Maurya ◽  
Mohd Washid Khan
Keyword(s):  
Nitric Oxide ◽  
Carbon Monoxide ◽  
Human Physiology ◽  
Hydrogen Sulfide ◽  
The Other ◽  
Normal Functioning ◽  
Comprehensive Review ◽  
Molecular Systems ◽  
Eye Health ◽  
Highly Sensitive

Abstract A set of well defined signaling molecules responsible for normal functioning of human physiology including nitric oxide along with carbon monoxide and hydrogen sulphide are referred as “gasotransmitters”. Due to their involvement in almost every system of a human body, the care of highly sensitive organs using these molecules as drugs represents highly fascinating area of research. In connection with these interesting aspects, the applied aspects of these gaseous molecules in maintaining healthy eye and vision have been targeted in this review. Several examples of eye-droppers including NORMs like latanoprost and nipradiol, CORMs like CORM-3 and CORM-A1, and Hydrogen sulfide releasing system like GYY4137 have been discussed in this context. Therefore the relation of these trio-gasotransmitters with the ophthalmic homeostasis on one hand, and de-infecting role on the other hand has been mainly highlighted. Some molecular systems capable of mimicking gasotransmitter action have also been introduced in connection with the titled theme.

THE HORMONAL COMPOSITION OF MILK IN PRODUCTIVE ANIMALS AND ITS SAFETY FOR HUMANS

2020 ◽  
Vol 1 (3) ◽  
pp. 313-321
Author(s):  
P.A. Popov ◽  
◽  
V.S. Babunova ◽  
Keyword(s):  
Trace Elements ◽  
Growth Factor ◽  
Dairy Products ◽  
The Body ◽  
The Other ◽  
Raw Material ◽  
Important Food ◽  
The Past ◽  
Highly Sensitive ◽  
And Control

Hormones are an integral part of milk and throughout lactation, the content of certain hormones is unstable. Hormones regulate the process of starting lactation of animals, the lactation process itself, and also the other functions of the body. Milk is of great importance for the growth of young animals and the formation of immunity. Milk is a special product in the diet and is an important food and raw material for the production of dairy products for people. It contains a large amount of protein, fat, carbohydrates, vitamins and trace elements in biologically available form. But at the same time, over the past few years, more and more evidence has emerged that hormones in dairy products can impact on human health. Thus, some estrogens and insulin-like growth factor IGF-1 are involved in the initiation and provocation of breast, prostate and endometrial tumors. That’s why, it is necessary to normalize and control the content of certain hormones in milk with highly sensitive methods.

scholarly journals Transferrin-Conjugated SNALPs Encapsulating 2′-O-Methylated miR-34a for the Treatment of Multiple Myeloma

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Immacolata Scognamiglio ◽  
Maria Teresa Di Martino ◽  
Virginia Campani ◽  
Antonella Virgilio ◽  
Aldo Galeone ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Zeta Potential ◽  
Lipid Vesicles ◽  
Significant Inhibition ◽  
The Other ◽  
Transferrin Receptors ◽  
Proof Of Concept ◽  
Wild Type ◽  
Chemical Conjugation ◽  
Mean Size

Stable nucleic acid lipid vesicles (SNALPs) encapsulating miR-34a to treat multiple myeloma (MM) were developed. Wild type or completely 2′-O-methylated (OMet) MiR-34a was used in this study. Moreover, SNALPs were conjugated with transferrin (Tf) in order to target MM cells overexpressing transferrin receptors (TfRs). The type of miR-34a chemical backbone did not significantly affect the characteristics of SNALPs in terms of mean size, polydispersity index, and zeta potential, while the encapsulation of an OMet miR-34a resulted in a significant increase of miRNA encapsulation into the SNALPs. On the other hand, the chemical conjugation of SNALPs with Tf resulted in a significant decrease of the zeta potential, while size characteristics and miR-34a encapsulation into SNALPs were not significantly affected. In an experimental model of MM, all the animals treated with SNALPs encapsulating miR-34a showed a significant inhibition of the tumor growth. However, the use of SNALPs conjugated with Tf and encapsulating OMet miR-34a resulted in the highest increase of mice survival. These results may represent the proof of concept for the use of SNALPs encapsulating miR-34a for the treatment of MM.

Stability Analysis of Supply Chain Cooperation Contract under Asymmetric Information

2010 ◽  
Vol 44-47 ◽  
pp. 794-798 ◽  
Author(s):  
Xin Ma
Keyword(s):  
Game Theory ◽  
Supply Chain ◽  
Repeated Games ◽  
Information Structure ◽  
Transition Period ◽  
Information Economics ◽  
Real Life ◽  
The Other ◽  
Game Equilibrium ◽  
The Stability

The stability of cooperation contract is the result of abandon opportunistic behavior in the process of repeated games among the enterprise and the other subjects in the supply chain from long-term interests, and is also the foundation of healthy development for the whole supply chain. But in real life cooperation contract instability everywhere for a variety of reasons, such as ethical considerations, institutional factors, cultural factors and special reasons during the transition period and so on. From the perspective of information economics and game theory, the main game process of cooperation between enterprise and the other subjects in supply chain is not only the game of information, but also the game of interests. Information structure and the interesting structure are the important factors for the subjects of the game of the implementation of decisions and the basic contractual constraints for cooperative game equilibrium. Cooperation behaviors among the enterprise and the other subjects in the supply chain were studied on the basis of game theory, and the stability of cooperation contract is also being discussed in this paper.

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