scholarly journals Extraction of the Structural Properties of Skin Tissue via Diffuse Reflectance Spectroscopy: An Inverse Methodology

Sensors ◽  
2021 ◽  
Vol 21 (11) ◽  
pp. 3745
Author(s):  
Bin Chen ◽  
Yong Zhang ◽  
Shang Gao ◽  
Dong Li

For the laser treatment of vascular dermatosis, the blood vessel morphology and depth in skin tissue is essential to achieve personalized intelligent therapy. The morphology can be obtained from the laser speckle imaging, and vessel depth was extracted by an inverse methodology based on diffuse reflectance spectrum. With optimized spot size of 0.5 mm and known optical properties, the proposed method was experimentally validated via the spectral measurement of microcapillary with known size and depth embedded in an epoxy resin-based skin phantom. Results prove that vessel depth can be extracted with an average relative error of 5%, thereby providing the foundation for a personalized, precise, and intelligent laser treatment of vascular dermatosis.

2002 ◽  
Vol 56 (10) ◽  
pp. 1329-1336 ◽  
Author(s):  
Guillaume Dupuis ◽  
Mady Elias ◽  
Lionel Simonot

Fiber-optics reflectance spectroscopy is used to identify pigments in pictorial layers of works of art thanks to a spectra database of dry powdered mineral pigments. Measurements are noninvasive, without any contact, and can be implemented in situ, without moving the work of art under investigation from its conservation place. The experimental device, using the special back-scattering configuration, is briefly presented. The protocol leading to the constitution of the spectra database of dry mineral pigments is described. Unlike other studies, this protocol has been developed to emphasize multiple scattering of light by elementary pigments in comparison with specular reflection on the surface of the sample. In these conditions, the diffuse reflectance spectrum is the label of the mineral pigment. The numerical processing of pigment identification is detailed. Both the influences of the roughness of the studied surface and of a possible varnish layer are taken into account when numerical identification is implemented. Several applications on patrimonial works of art are reported.


2019 ◽  
Vol 25 (3) ◽  
pp. 141-147 ◽  
Author(s):  
Kawthar Shurrab ◽  
Nabil Kochaji ◽  
Wesam Bachir

Abstract Today, to establish a diagnosis, the patient must undergo a biopsy followed by histopathological diagnosis, which causes unnecessary cost, patient trauma, and time delay to obtain a diagnosis. However, the metastases can be discovered by diffuse reflectance spectroscopy, which is a simple method that investigates the light distribution within tissue. The theme of this paper is the use of diffuse reflectance spectroscopy (DRS) to determine the optical spectrum of hamster specimen’s tissue and to differentiate biological changes due to laser irradiation (scattering, and cell changes) under the skin. DRS measurements were made on healthy and malignant tissue to diagnose the stages of cancer formation using a fiber-optic probe. The results show that malignant tissue is characterized by a significant decrease in diffuse reflectance spectrum compared to normal tissue.


2014 ◽  
Vol 44 (1) ◽  
pp. 69-75 ◽  
Author(s):  
S A Lisenko ◽  
M M Kugeiko ◽  
V A Firago ◽  
A N Sobchuk

2006 ◽  
Vol 39 (18) ◽  
pp. 41-46
Author(s):  
Emilie Péry ◽  
Walter C.P.M. Blondel ◽  
Cédric Thomas ◽  
Jacques Didelon ◽  
François Guillemin

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