scholarly journals Short- and Long-Term Effects of a Scapular-Focused Exercise Protocol for Patients with Shoulder Dysfunctions—A Prospective Cohort

Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2888
Author(s):  
Cristina dos Santos ◽  
Mark A. Jones ◽  
Ricardo Matias
Keyword(s):  
Rating Scale ◽  
Pain Syndrome ◽  
Anterior Shoulder Instability ◽  
Scapular Dyskinesis ◽  
Long Term Effects ◽  
Exercise Protocol ◽  
Short And Long Term ◽  
And Function

Current clinical practice lacks consistent evidence in the management of scapular dyskinesis. This study aims to determine the short- and long-term effects of a scapular-focused exercise protocol facilitated by real-time electromyographic biofeedback (EMGBF) on pain and function, in individuals with rotator cuff related pain syndrome (RCS) and anterior shoulder instability (ASI). One-hundred and eighty-three patients were divided into two groups (n = 117 RCS and n = 66 ASI) and guided through a structured exercise protocol, focusing on scapular dynamic control. Values of pain and function (shoulder pain and disability index (SPADI) questionnaire, complemented by the numeric pain rating scale (NPRS) and disabilities of the arm, shoulder, and hand (DASH) questionnaire) were assessed at the initial, 4-week, and 2-year follow-up and compared within and between. There were significant differences in pain and function improvement between the initial and 4-week assessments. There were no differences in the values of DASH 1st part and SPADI between the 4-week and 2-year follow-up. There were no differences between groups at the baseline and long-term, except for DASH 1st part and SPADI (p < 0.05). Only 29 patients (15.8%) had a recurrence episode at follow-up. These results provide valuable information on the positive results of the protocol in the short- and long-term.

scholarly journals Long-Term Effects of the Treatment of Depressive Female Inpatients in a Naturalistic Study: Is Early Improvement a Valid Predictor of Outcome?

2014 ◽  
Vol 2014 ◽  
pp. 1-8
Author(s):  
Elian Zuercher-Huerlimann ◽  
Martin grosse Holtforth ◽  
Ernst Hermann
Keyword(s):  
Binary Logistic Regression ◽  
Inpatient Setting ◽  
Long Term Effects ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Early Improvement ◽  
Valid Predictor ◽  
Short And Long Term

Objectives.To examine the predictive value of early improvement for short- and long-term outcome in the treatment of depressive female inpatients and to explore the influence of comorbid disorders (CD).Methods.Archival data of a naturalistic sample of 277 female inpatients diagnosed with a depressive disorder was analyzed assessing the BDI at baseline, after 20 days and 30 days, posttreatment, and after 3 to 6 months at follow-up. Early improvement, defined as a decrease in the BDI score of at least 30% after 20 and after 30 days, and CD were analyzed using binary logistic regression.Results.Both early improvement definitions were predictive of remission at posttreatment. Early improvement after 30 days showed a sustained treatment effect in the follow-up phase, whereas early improvement after 20 days failed to show a persistent effect regarding remission at follow-up. CD were not significantly related neither at posttreatment nor at follow-up. At no time point CD moderated the prediction by early improvement.Conclusions.We show that early improvement is a valid predictor for short-term remission and at follow-up in an inpatient setting. CD did not predict outcome. Further studies are needed to identify patient subgroups amenable to more tailored treatments.

scholarly journals Emotional Reactivity and Wellbeing of Adolescents During the COVID-19 Pandemic: Short and Long Term Effects and The Impact of Social and Socioeconomic Stressors

2021 ◽  
Author(s):  
Kayla Green ◽  
Suzanne van de Groep ◽  
Sophie Sweijen ◽  
Andrik Becht ◽  
Moniek Buijzen ◽  
...  
Keyword(s):  
Young Adults ◽  
Emotional Reactivity ◽  
Formative Period ◽  
Long Term Effects ◽  
Daily Diary Study ◽  
Adolescent Sample ◽  
Short And Long Term ◽  
The Impact

Adolescence is a formative period for socio-emotional development which is threatened by the COVID-19 pandemic. The current longitudinal study examined the impact of the pandemic on young people’s mood, emotional reactivity, and wellbeing (i.e., operationalized as balancing needs of self and others). Hence, we conducted an online two-week daily diary study among 462 Dutch adolescents (Mage = 15.27 years, 64% females) and 371 young adults (Mage = 21.49 years, 81% females) in May 2020, with a follow-up to study long-term effects in November 2020 (N = 238 and 231, respectively adolescents and young adults). In May 2020, young adults and older relative to younger adolescents showed higher levels and more fluctuations in tension and depression and lower levels of vigor. Vigor levels decreased and tension and depression levels increased between May 2020 and November 2020, especially for younger adolescents. A closer examination in the adolescent sample, revealed positive associations between instability of negative emotions (i.e. tension and depression fluctuations) and the exposure to social and socioeconomic stressors (i.e. family stress and inequality of online homeschooling). Together, this study demonstrates vulnerability regarding young people’s mood and emotional reactivity during the COVID-19 pandemic, especially for adolescents who experience more stressors.

Management and Surveillance of Short- and Long-Term Sequelae of Radiation Therapy for the Treatment of Pediatric Brain Tumors

2020 ◽  
Vol 18 (06) ◽  
pp. 307-312
Author(s):  
Fred Chiu-Lai Lam ◽  
Ekkehard M Kasper ◽  
Anand Mahadevan
Keyword(s):  
Radiation Therapy ◽  
Brain Tumors ◽  
Pediatric Brain Tumors ◽  
Special Edition ◽  
Long Term Effects ◽  
Transition Into Adulthood ◽  
Short And Long Term ◽  
Pediatric Brain

AbstractRadiation therapy (RT) is a mainstay for the treatment of pediatric brain tumors. As improvements in and sophistication of this modality continue to increase the survival of patients, the long-term sequelae of RT pose significant challenges in the clinical management of this patient population as they transition into adulthood. In this special edition, we review the short- and long-term effects of RT for the treatment of pediatric brain tumors and the necessary surveillance required for follow-up.

scholarly journals Short- and Long-Term Effects of DBS on Gait in Parkinson's Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Hana Brozova ◽  
Isabelle Barnaure ◽  
Evzen Ruzicka ◽  
Jan Stochl ◽  
Ron Alterman ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Repeated Measures ◽  
Rating Scale ◽  
Long Term Effects ◽  
Short Term ◽  
Short And Long Term ◽  
Mean Time ◽  
Stn Dbs

The aim was to compare the short and long-term effects of subthalamic nucleus (STN) deep brain stimulation (DBS) on gait dysfunction and other cardinal symptoms of Parkinson's disease (PD). Two groups of patients were studied. The first group (short-term DBS, n = 8) included patients recently implanted with STN DBS (mean time since DBS 15.8 months, mean age 58.8 years, PD duration 13 years); the second group (long-term DBS, n = 10) included patients with at least 5 years of DBS therapy (mean time since DBS 67.6 months, mean age 61.7 years, PD duration 17.1 years). Both groups were examined using the Unified Parkinson's Disease Rating Scale (UPDRS) and Gait and Balance scale (GABS) during four stimulation/medication states (ON/OFF; OFF/OFF; OFF/ON; ON/ON). Data were analyzed using repeated measures ANOVA with time since implantation (years) between groups and medication or DBS effect (ON, OFF) within groups. In the short-term DBS group, stimulation improved all UPDRS subscores similar to dopaminergic medications. In particular, average gait improvement was over 40% (p = 0.01), as measured by the UPDRS item 29 and GABS II. In the long-term DBS group, stimulation consistently improved all clinical subscores with the exception of gait and postural instability. In these patients, the effect of levodopa on gait was partially preserved. Short-term improvement of gait abnormalities appears to significantly decline after 5 years of STN DBS in PD patients, while effectiveness for other symptoms remains stable. Progressive non-dopaminergic (non-DBS responsive) mechanisms or deleterious effects of high frequency STN stimulation on gait function may play a role.

scholarly journals Subthalamic Nucleus Stimulation in Pediatric Isolated Dystonia: A 10-Year Follow-up

2020 ◽  
Vol 47 (3) ◽  
pp. 328-335
Author(s):  
Wenying Xu ◽  
Hongxia Li ◽  
Chencheng Zhang ◽  
Bomin Sun ◽  
Yiwen Wu ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Subthalamic Nucleus ◽  
Rating Scale ◽  
Motor Score ◽  
Age At Surgery ◽  
Short And Long Term ◽  
The Mean ◽  
Stn Dbs

ABSTRACT:Objective:To evaluate the short-term and long-term clinical effectiveness and safety of subthalamic nucleus deep brain stimulation (STN-DBS) for medically intractable pediatric isolated dystonia.Methods:Using a longitudinal retrospective design, we assessed the clinical outcomes of nine patients who underwent STN-DBS for treatment-refractory pediatric isolated dystonia one decade ago (mean age at surgery: 15.9 ± 4.5 years). The primary clinical outcome used was assessed by retrospective video analyses of patients’ dystonia symptoms using the Burke–Fahn–Marsden Dystonia Rating Scale (BFMDRS). Clinical assessments were performed at baseline, 1-year follow-up (1-yr FU), and 10-year follow-up (10-yr FU). Adverse side effects, including surgery-related, device-related, and stimulation-related effects, were also documented.Results:After STN-DBS surgery, the mean improvement in the BFMDRS motor score was 77.1 ± 26.6% at 1-yr FU and 90.4 ± 10.4% at 10-yr FU. Similarly, the mean BFMDRS disability score was improved by 69.5 ± 13.6% at 1-yr FU and by 86.5 ± 13.9% at 10-yr FU. The clinical improvements gained at 10-yr FU were significantly larger than those observed at 1-yr FU. Negative correlations were found between the duration of disease to age at surgery ratio (DD/AS) and the improvements in the BFMDRS motor score and total score at 1-yr FU and 10-yr FU.Conclusion:To our knowledge, this study provides the first clinical evidence for the short- and long-term effectiveness and safety of STN-DBS for pediatric isolated dystonia. Additionally, putative evidence is provided that earlier STN-DBS intervention in patients with refractory pediatric isolated dystonia may improve short- and long-term clinical outcomes.

scholarly journals Citicoline and COVID-19-Related Cognitive and Other Neurologic Complications

2021 ◽  
Vol 12 (1) ◽  
pp. 59
Author(s):  
Yuda Turana ◽  
Michael Nathaniel ◽  
Robert Shen ◽  
Soegianto Ali ◽  
Rajender R. Aparasu
Keyword(s):  
Neurological Diseases ◽  
Treatment Options ◽  
Neurological Complications ◽  
Neurologic Complications ◽  
Long Term Effects ◽  
Short And Long Term ◽  
And Function ◽  
Natural Metabolite ◽  
Anti Inflammation

With growing concerns about COVID-19’s hyperinflammatory condition and its potentially damaging impact on the neurovascular system, there is a need to consider potential treatment options for managing short- and long-term effects on neurological complications, especially cognitive function. While maintaining adequate structure and function of phospholipid in brain cells, citicoline, identical to the natural metabolite phospholipid phosphatidylcholine precursor, can contribute to a variety of neurological diseases and hypothetically toward post-COVID-19 cognitive effects. In this review, we comprehensively describe in detail the potential citicoline mechanisms as adjunctive therapy and prevention of COVID-19-related cognitive decline and other neurologic complications through citicoline properties of anti-inflammation, anti-viral, neuroprotection, neurorestorative, and acetylcholine neurotransmitter synthesis, and provide a recommendation for future clinical trials.

Treatment of Sleep-maintenance Insomnia: A Case Study Using Time-series Analysis

1986 ◽  
Vol 14 (4) ◽  
pp. 326-333 ◽  
Author(s):  
E. Hohenberger-Sieber ◽  
G. Mueller ◽  
L. Schindler
Keyword(s):  
Time Series ◽  
Time Series Analysis ◽  
Therapeutic Approach ◽  
Treatment Programme ◽  
Long Term Effects ◽  
Sleep Maintenance ◽  
Short And Long Term

A behaviour-therapeutic approach in a case of chronic insomnia is illustrated. Based on research reported in the literature the treatment programme consists of sleep-related interventions as well as of training in coping with conditions which influence sleep negatively. Data on the short- and long-term effects of therapy, especially during the follow-up period of two years, are discussed.

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