scholarly journals Autosegmentation of Prostate Zones and Cancer Regions from Biparametric Magnetic Resonance Images by Using Deep-Learning-Based Neural Networks

Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2709
Author(s):  
Chih-Ching Lai ◽  
Hsin-Kai Wang ◽  
Fu-Nien Wang ◽  
Yu-Ching Peng ◽  
Tzu-Ping Lin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Deep Learning ◽  
Magnetic Resonance ◽  
Peripheral Zone ◽  
Magnetic Resonance Images ◽  
Dice Similarity Coefficient ◽  
Resonance Imaging ◽  
Prostate Mri ◽  
Diffusion Weighted Images ◽  
Apparent Diffusion

The accuracy in diagnosing prostate cancer (PCa) has increased with the development of multiparametric magnetic resonance imaging (mpMRI). Biparametric magnetic resonance imaging (bpMRI) was found to have a diagnostic accuracy comparable to mpMRI in detecting PCa. However, prostate MRI assessment relies on human experts and specialized training with considerable inter-reader variability. Deep learning may be a more robust approach for prostate MRI assessment. Here we present a method for autosegmenting the prostate zone and cancer region by using SegNet, a deep convolution neural network (DCNN) model. We used PROSTATEx dataset to train the model and combined different sequences into three channels of a single image. For each subject, all slices that contained the transition zone (TZ), peripheral zone (PZ), and PCa region were selected. The datasets were produced using different combinations of images, including T2-weighted (T2W) images, diffusion-weighted images (DWI) and apparent diffusion coefficient (ADC) images. Among these groups, the T2W + DWI + ADC images exhibited the best performance with a dice similarity coefficient of 90.45% for the TZ, 70.04% for the PZ, and 52.73% for the PCa region. Image sequence analysis with a DCNN model has the potential to assist PCa diagnosis.

scholarly journals Deep Learning-Based Methods for Prostate Segmentation in Magnetic Resonance Imaging

2021 ◽  
Vol 11 (2) ◽  
pp. 782 ◽  
Author(s):  
Albert Comelli ◽  
Navdeep Dahiya ◽  
Alessandro Stefano ◽  
Federica Vernuccio ◽  
Marzia Portoghese ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Deep Learning ◽  
Magnetic Resonance ◽  
Prostate Gland ◽  
Dice Similarity Coefficient ◽  
Processing Unit ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Central Processing ◽  
Prostate Segmentation

Magnetic Resonance Imaging-based prostate segmentation is an essential task for adaptive radiotherapy and for radiomics studies whose purpose is to identify associations between imaging features and patient outcomes. Because manual delineation is a time-consuming task, we present three deep-learning (DL) approaches, namely UNet, efficient neural network (ENet), and efficient residual factorized convNet (ERFNet), whose aim is to tackle the fully-automated, real-time, and 3D delineation process of the prostate gland on T2-weighted MRI. While UNet is used in many biomedical image delineation applications, ENet and ERFNet are mainly applied in self-driving cars to compensate for limited hardware availability while still achieving accurate segmentation. We apply these models to a limited set of 85 manual prostate segmentations using the k-fold validation strategy and the Tversky loss function and we compare their results. We find that ENet and UNet are more accurate than ERFNet, with ENet much faster than UNet. Specifically, ENet obtains a dice similarity coefficient of 90.89% and a segmentation time of about 6 s using central processing unit (CPU) hardware to simulate real clinical conditions where graphics processing unit (GPU) is not always available. In conclusion, ENet could be efficiently applied for prostate delineation even in small image training datasets with potential benefit for patient management personalization.

scholarly journals Tumor Segmentation in Contrast-Enhanced Magnetic Resonance Imaging for Nasopharyngeal Carcinoma: Deep Learning with Convolutional Neural Network

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Qiaoliang Li ◽  
Yuzhen Xu ◽  
Zhewei Chen ◽  
Dexiang Liu ◽  
Shi-Ting Feng ◽  
...  
Keyword(s):  
Neural Network ◽  
Magnetic Resonance Imaging ◽  
Deep Learning ◽  
Magnetic Resonance ◽  
Nasopharyngeal Carcinoma ◽  
Convolutional Neural Network ◽  
Tumor Segmentation ◽  
Dice Similarity Coefficient ◽  
Resonance Imaging ◽  
Contrast Enhanced

Objectives. To evaluate the application of a deep learning architecture, based on the convolutional neural network (CNN) technique, to perform automatic tumor segmentation of magnetic resonance imaging (MRI) for nasopharyngeal carcinoma (NPC). Materials and Methods. In this prospective study, 87 MRI containing tumor regions were acquired from newly diagnosed NPC patients. These 87 MRI were augmented to >60,000 images. The proposed CNN network is composed of two phases: feature representation and scores map reconstruction. We designed a stepwise scheme to train our CNN network. To evaluate the performance of our method, we used case-by-case leave-one-out cross-validation (LOOCV). The ground truth of tumor contouring was acquired by the consensus of two experienced radiologists. Results. The mean values of dice similarity coefficient, percent match, and their corresponding ratio with our method were 0.89±0.05, 0.90±0.04, and 0.84±0.06, respectively, all of which were better than reported values in the similar studies. Conclusions. We successfully established a segmentation method for NPC based on deep learning in contrast-enhanced magnetic resonance imaging. Further clinical trials with dedicated algorithms are warranted.

Functional information from magnetic resonance imaging

1995 ◽  
Vol 53 ◽  
pp. 84-85
Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Cancer Biology ◽  
Imaging Modality ◽  
Magnetic Resonance Images ◽  
Great Success ◽  
Functional Information ◽  
Resonance Imaging ◽  
High Resolution Mri

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.

scholarly journals Imaging findings of cerebral fat embolism syndrome: a case report

2020 ◽  
Vol 48 (9) ◽  
pp. 030006052095055
Author(s):  
Yali Wang ◽  
Zhihua Si ◽  
Jingzhe Han ◽  
Shuangqing Cao
Keyword(s):  
Magnetic Resonance ◽  
Fat Embolism ◽  
Magnetic Resonance Images ◽  
Resonance Imaging ◽  
Diffusion Weighted Images ◽  
Embolism Syndrome ◽  
Imaging Characteristics ◽  
Fluid Attenuated Inversion Recovery ◽  
Cerebral Fat Embolism Syndrome ◽  
Head Computed Tomography

Cerebral fat embolism (CFE) syndrome is relatively rare in clinical practice. Currently, there is no uniform standard of magnetic resonance imaging for the diagnosis of the disease. In this report, we present head computed tomography and magnetic resonance images (T2-weighted images, fluid-attenuated inversion recovery images, diffusion-weighted images, and susceptibility-weighted images) in a case of CFE. This report explains the imaging characteristics of CFE and improves the clinician’s understanding of this disease and its etiology.

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