scholarly journals A Study Validating the Estimation of Anterior Chamber Depth and Iridocorneal Angle with Portable and Non-Portable Slit-Lamp Microscopy

Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1436
Author(s):  
Eisuke Shimizu ◽  
Hiroyuki Yazu ◽  
Naohiko Aketa ◽  
Ryota Yokoiwa ◽  
Shinri Sato ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Strong Correlation ◽  
Objective Assessment ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Japanese Patients ◽  
Slit Lamp ◽  
Retrospective Case ◽  
Iridocorneal Angle ◽  
Kappa Value

This study assessed the anterior chamber depth (ACD) and iridocorneal angle using a portable smart eye camera (SEC) compared to the conventional slit-lamp microscope and anterior-segment optical coherence tomography (AS-OCT). This retrospective case-control study included 170 eyes from 85 Japanese patients. The correlation between the ACD evaluations conducted with the SEC and conventional slit-lamp was high (r = 0.814). The correlation between the Van-Herick Plus grade obtained using two devices was also high (r = 0.919). A high kappa value was observed for the Van-Herick Plus grading (Kappa = 0.757). A moderate correlation was observed between the ACD measured using AS-OCT and the slit-lamp image acquired with the conventional slit-lamp microscope and SEC (r = 0.609 and 0.641). A strong correlation was observed between the trabecular-iris angle (TIA) measured using AS-OCT and Van-Herick Plus grade obtained with the conventional slit-lamp microscope and SEC (r = 0.702 and 0.764). Strong correlations of ACD evaluation and high kappa value of the Van-Herick Plus grading indicated the adequate subjective assessment function of the SEC. Moderate correlations between the ACD objective measurement and evaluation and strong correlation between the TIA and Van-Herick Plus grade suggested the good objective assessment function of the SEC. The SEC demonstrated adequate performance for ACD evaluation and angle estimation.

scholarly journals Evaluation the Acute Effects of Hyperbaric Oxygen Therapy on Eye Anterior Segment Morphology and on İntraocular Pressure

2021 ◽  
Author(s):  
Fatih Akıncı ◽  
Abdullah Arslan ◽  
Muammer Özcimen
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Central Corneal Thickness ◽  
Oxygen Therapy ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Iridocorneal Angle

Abstract Purpose: In this study the acute effects of 1 session of hyperbaric oxygen therapy on eye anterior segment morphology and on intraocular pressure was evaluated.Materials and methods: 30 patients taking hyperbaric oxygen therapy for different indications were included in this prospective study. Only the right eye per patient was included in the study. The refractive errors were measured with autorefractometry, intraocular pressures were measured with pneumatic tonometry; anterior segment parameters pachymetry, keratometry, anterior chamber depth and iridocorneal angle values were measured with corneal topography prior to and 24 hours after 1 session of hyperbaric oxygen therapy.Results: In this study 30 eyes from a total of 30 patients were evaluated; 19 men (% 64) and 11 women (% 36). Median age was 44.33 ±16.12 (Age range 18-80 years). Mean intraocular pressure was 13.7 ±4,16 mmHg (milimetermercuries), mean central corneal thickness was 531.9 ±28.24 μm, mean anterior chamber depth was 3.30 ±0.375 mm, mean iridocorneal angle value was 35.3± 6.61 degrees before hyperbaric oxygen therapy. The mean intraocular pressure was 12.66±4,54 mmHg, mean central corneal thickness was 529.43± 26.68 μm, mean anterior chamber depth was 3.28±0.372 mm, mean iridocorneal angle value was 34.5±6.42 degrees after HBOT. A statistically significant decrease in these values were recorded. No statistically significant changes were found in spheric equivalent and keratometry values of the patients before and after HBOT.Conclusions: After one session of HBOT a decrease in intraocular pressure, central corneal thickness, anterior chamber depth and iridocorneal angles of patients were observed; keratometry and spheric equivalent values remained unchanged. More studies are needed in order to use the effects of HBOT on anterior segment morphology and on intraocular pressure for situations like glaucoma, corneal edema etc.

scholarly journals Machine Learning-Guided Prediction of Central Anterior Chamber Depth Using Slit Lamp Images from a Portable Smartphone Device

Biosensors ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 182
Author(s):  
David Chen ◽  
Yvonne Ho ◽  
Yuki Sasa ◽  
Jieying Lee ◽  
Ching Chiuan Yen ◽  
...  
Keyword(s):  
Machine Learning ◽  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Training Data ◽  
Portable Devices ◽  
Anatomical Landmarks ◽  
Strong Positive Correlation ◽  
Slit Lamp ◽  
History Of

There is currently no objective portable screening modality for narrow angles in the community. In this prospective, single-centre image validation study, we used machine learning on slit lamp images taken with a portable smartphone device (MIDAS) to predict the central anterior chamber depth (ACD) of phakic patients with undilated pupils. Patients 60 years or older with no history of laser or intraocular surgery were recruited. Slit lamp images were taken with MIDAS, followed by anterior segment optical coherence tomography (ASOCT; Casia SS-1000, Tomey, Nagoya, Japan). After manual annotation of the anatomical landmarks of the slit lamp photos, machine learning was applied after image processing and feature extraction to predict the ACD. These values were then compared with those acquired from the ASOCT. Sixty-six eyes (right = 39, 59.1%) were included for analysis. The predicted ACD values formed a strong positive correlation with the measured ACD values from ASOCT (R2 = 0.91 for training data and R2 = 0.73 for test data). This study suggests the possibility of estimating central ACD using slit lamp images taken from portable devices.

scholarly journals Precise geometry of the anterior chamber of the eye by means of OCT imaging.

2018 ◽  
Vol 10 (3) ◽  
pp. 67
Author(s):  
Marta Katarzyna Skrok ◽  
Damian Siedlecki ◽  
David Alonso-Caneiro
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Distortion Correction ◽  
Diagnostic Methods ◽  
Optical Distortion ◽  
Optical Coherence ◽  
Refractive Index Measurement ◽  
Iridocorneal Angle

Nowadays medicine highly relies on non-invasive optical diagnostic methods. The likewise situation is in the case of ophthalmology, especially in diagnosis of anterior segment eye diseases, where optical coherence tomography (OCT) plays inestimable role. OCT devices can do fast, painless measurements of the anterior segment of the eye. Nonetheless it should be remembered that the OCT images are burdened with an optical distortion and they doesn’t reflect the true geometry of the eye. This study presents an algorithm for correcting the distortion in OCT images and reflecting true parameters of the anterior segment of the eye. Full Text: PDF ReferencesA. Podoleanu, I. Charalambous, L. Plesea, A. Dogariu, R. Rosen, "Correction of distortions in optical coherence tomography imaging of the eye", Phys. Med. Biol. 49(7), 1277 (2004). CrossRef S. Ortiz, D. Siedlecki, I. Grulkowski, L. Remon, D. Pascual, M. Wojtkowski, S. Marcos, "Optical distortion correction in Optical Coherence Tomography for quantitative ocular anterior segment by three-dimensional imaging", Opt. Express 18, 2782 (2010). CrossRef F. LaRocca, S.J. Chiu, R.P. McNabb, A.N. Kuo, J.A. Izatt, S. Farsiu, "Robust automatic segmentation of corneal layer boundaries in SDOCT images using graph theory and dynamic programming", Biom. Opt. Express 2(6), 1524 (2011). CrossRef S.A. Read et al., "Anterior eye tissue morphology: Scleral and conjunctival thickness in children and young adults", Sci. Rep. 6, 33796 (2016). CrossRef S.R. Uhlhorn, D. Borja, F. Manns, J.-M. Parel, "Refractive index measurement of the isolated crystalline lens using optical coherence tomography", Vision Res., 48(27), 2732 (2008). CrossRef R. Koprowski, Z. Wróbel, S. Wilczyński, A. Nowińska, E. Wylęgała, "Methods of measuring the iridocorneal angle in tomographic images of the anterior segment of the eye", Biomed. Eng. Online, 12, 40 (2013). CrossRef D.P. Pinero, A.B. Plaza Puche, J.L. Alio, "Corneal diameter measurements by corneal topography and angle-to-angle measurements by optical coherence tomography: Evaluation of equivalence", J. Cataract Refract. Surg. 34, 126 (2008). CrossRef B. Urban, M. Krętowska, M. Szumiński, A. Bakunowicz-Łazarczyk, " Evaluation of anterior chamber depth measurements in emmetropic, hypermetropic and myopic eyes in children and adolescents using OCT Visante", Klinika Oczna 114(1), 18 (2012). DirectLink L. Chen, D. Chernyak, "Pupil Changes under Scotopic and Photopic illumination", Invest. Ophthalmol. Vis. Sci. 54, 1524 (2013). DirectLink D. Monsalvez-Romin, A.J. del Aguila-Carrasco, T. Ferrer-Blasco, J.J. Esteve-Taboada, R Montes-Mico, Evaluation of the iridocorneal angle with accommodation using optical coherence tomography", Int. J. Ophthalmol. 10(10), 1614 (2017). CrossRef

scholarly journals Changes in Iridocorneal Angle Configuration and Intraocular Pressure during Smartphone Use under Room Light

2021 ◽  
Vol 62 (9) ◽  
pp. 1252-1258
Author(s):  
Seong Taik Lee ◽  
Su Jin Park ◽  
Yong Koo Kang ◽  
Jae Pil Shin ◽  
Dai Woo Kim ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Iridocorneal Angle ◽  
Room Light ◽  
Reading Text ◽  
Iop Measurement ◽  
Smartphone Use ◽  
Patient At Risk

Purpose: To investigate changes in intraocular pressure (IOP) and iridocorneal angle (ICA) configuration during smartphone use under room light. Methods: We included healthy adults aged 19-35 years with no ophthalmological abnormalities. All read text on a smartphone for 6 minutes under room light. IOP was measured via rebound tonometry at baseline and at 2, 4, and 6 minutes. ICA images were obtained via anterior segment optical coherence tomography after each IOP measurement. After 6 minutes, participants stopped reading text and rested for 2 minutes. IOP was then measured again. Results: The IOP significantly increased at 2, 4, and 6 minutes of reading compared to baseline (p < 0.001) but recovered to baseline after 2 minutes of rest (p = 1.000). The anterior chamber depth decreased significantly, and the anterior chamber angle width increased after 6 minutes of smartphone reading (both p < 0.05). Conclusions: IOP increased when reading smartphone text under room light but the ICA did not change. Prolonged smartphone reading is inappropriate for a patient at risk of glaucoma or glaucoma progression. Such patients should be cautioned.

Intraocular Pressure Spikes after Aflibercept Intravitreal Injections

2016 ◽  
Vol 236 (1) ◽  
pp. 43-47 ◽  
Author(s):  
Hussam El Chehab ◽  
Emilie Agard ◽  
Aurélie Russo ◽  
Ygal Boujnah ◽  
Corinne Dot
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Angle Closure ◽  
Iridocorneal Angle ◽  
Chamber Volume ◽  
Short Period ◽  
Anterior Chamber Volume ◽  
Acute Increase

The objective of this study was to assess the intraocular pressure (IOP) as well as the anatomical modifications of the anterior segment following an aflibercept injection. Patients underwent an aflibercept intravitreal injection (IVI) (0.05 ml) with a 30.5-gauge needle and an antireflux system. IOP was assessed before injection (T0), immediately after (T1), and 5 min (T5), 15 min (T15), and 45 min (T45) after the IVI. Before the IVI and immediately after the T1 measurement, a PENTACAM® acquisition was used to evaluate the anterior chamber parameters (anterior chamber volume, depth and measure of the iridocorneal angle). At T0, IOP was 12.9 ± 1.3 mm Hg. IOP significantly increased after IVI (42.7 ± 3 mm Hg, p < 0.001). IOP returned to baseline at T45 (13.0 ± 1.2 mm Hg, p = 0.877). Anterior chamber volume decreased after IVI (160.6 vs. 168.3 mm3, p = 0.002). No significant changes were found for iridocorneal angle and anterior chamber depth. Aflibercept IVI causes an acute increase in IOP over a short period without iridocorneal angle closure.

scholarly journals Polypharmacy-associated potential contraindications of drug prescriptions in patients with primary angle closure disease in a real-world setting

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Fumiaki Tanaka ◽  
Naoki Shibatani ◽  
Kazumi Fujita ◽  
Hiroaki Ikesue ◽  
Satoru Yoshimizu ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Anterior Chamber Depth ◽  
Japanese Patients ◽  
Median Number ◽  
Angle Closure ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Number Of Patients ◽  
Multiple Drugs

Abstract Background Primary angle closure disease (PACD) is a type of glaucoma in which the intraocular pressure (IOP) is increased because of the blockage of the anterior chamber angle. Medications contraindicated for patients with PACD, such as anticholinergics, cause mydriasis, and can elevate IOP. However, anticholinergics are currently contraindicated only for primary angle closure glaucoma (PACG) in Japanese package inserts. In this study, we investigated the prescription status of medications contraindicated for PACD, such as anticholinergics, in patients with PACD scheduled for eye surgeries. Methods Forty-three Japanese patients diagnosed with PACD at Kobe City Eye Hospital, Japan, and scheduled hospitalization for eye surgeries between December 2017 and July 2018, were included. Data, including sex, age, diagnosis, IOP, anterior chamber depth, and patients’ regular medications prior to hospitalization, were collected for each patient from the electronic medical records. Results The number of patients with chronic primary angle closure (CPAC) and acute primary angle closure (APAC) was 35 (81.4%) and 8 (18.6%), respectively. Among all the 43 patients with PACD, 8 (18.6%) received 15 medications that are potentially contraindicated for PACD by non-ophthalmologist. According to medication categories, benzodiazepine hypnotics were the most commonly prescribed. Among the 8 patients with APAC, 2 (25.0%) had routinely received medications contraindicated for PACD. The median number of all kinds of prescriptions on the day of hospitalization was significantly higher for patients who received medications contraindicated for PACD than for those who did not receive them (p = 0.010). Conclusions About 20% of patients with PACD received medications potentially contraindicated for PACD, such as anticholinergics. Attention should be paid to patients prescribed multiple drugs for adverse events, such as increase in intraocular pressure.

scholarly journals Changes in anterior segment optical coherence tomography following pars plana vitrectomy without tamponade

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Alireza Khodabande ◽  
Massood Mohammadi ◽  
Hamid Riazi-Esfahani ◽  
Shahab Karami ◽  
Massood Mirghorbani ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Pars Plana Vitrectomy ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Optical Coherence ◽  
Mean Values ◽  
Iop Measurement ◽  
Pars Plana ◽  
The Mean

Abstract Background To evaluate changes in anterior segment morphology on anterior segment optical coherence tomography (AS-OCT) following pars plana vitrectomy (PPV) without tamponade. Methods Patients who underwent PPV without tamponade for epiretinal membrane were evaluated. Eligible patients underwent intraocular pressure (IOP) measurement and AS-OCT preoperatively as well as 1 month and 6 months post-operatively. Anterior chamber width (ACW), anterior chamber depth (ACD), trabecular iris angle (TIA), angle opening distance at 500 and 750 µm (AOD), and trabecular iris space area at 500 and 750 µm (TISA) at four quadrants were recorded and analyzed. Additionally, the mean values of TIA (MTIA), AOD (MAOD), and TISA (MTISA) for each eye (mean of four quadrants) were analyzed. Results 23 patients completed the study. The mean age of participants was 56.4 ± 3.6 years of age and 13/23 (56%) were female. Mean IOP of patients was 18.1 ± 1.1, 18.3 ± 1.1, and 18.1 ± 1.2 preoperatively,1 month post-operatively, and 6 months post-operatively, respectively. (p = 0.83). No difference was detected post-operatively in measurements of ACW, ACD, MTIA, MAOD500, MAOD750, MTISA500, and MTISA750. Conclusion Pars plana vitrectomy without tamponade was not associated with changes in anterior chamber morphology.

Effect of light backscattering from anterior segment structures on automated flare meter measurements

2021 ◽  
pp. 112067212110393
Author(s):  
Murat Hasanreisoglu ◽  
Cem Kesim ◽  
Duygu Yalinbas ◽  
Mervenur Yilmaz ◽  
Nur Sena Uzunay ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Scattered Light ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Laser Flare Photometry ◽  
Aqueous Flare ◽  
Group I ◽  
Lens Density ◽  
Laser Flare ◽  
Group Ii

Background: To evaluate effect of maximal anterior cortical lens density, iris scatter and anterior chamber depth on laser flare photometry. Methods: Patients diagnosed with clinical uveitis were enrolled in the study. Clinical flare gradings were recorded upon the Standardization of Uveitis Nomenclature. Aqueous flare was measured with an automated device (Kowa FM-700). Back-scattering from anterior cortical lens and anterior iris surface was calculated from Scheimpflug images. A curvilinear regression model was used to calculate estimated values for each clinical grade. These values were used to split cases in Group I (laser flare photometry lower than estimated) and Group II (laser flare photometry higher than estimated). Mean anterior chamber depth, pupil aperture, maximal anterior cortical lens density and iris scatter values were compared between two groups. A stepwise multiple regression analysis was performed to determine the effect of clinical flare gradings and ocular parameters on aqueous flare measurements. Results: The study included 228 eyes of 114 cases. Scheimpflug images were obtained from 105 eyes. Estimated aqueous flare measurements (in photons/milliseconds) were 4.87, 8.50, 14.81, 25.83, 45.04 and 136.93 for 0, 0.5+, 1+, 1.5+, 2+ and 3+ clinical flare respectively. Group II had higher maximal anterior cortical lens density than Group I (96.6 ± 37.1 vs 77.9 ± 17.1 pixel unit, p = 0.001). The measured aqueous flare was significantly related to clinical flare, maximal anterior cortical lens density and pupil aperture (adjusted R2: 0.480, p < 0.001). Conclusion: The back-scattered light from anterior cortical lens could affect laser flare photometry measurements. This effect might be quantified by Scheimpflug imaging.

scholarly journals Anatomical and Visual Effects of Implantable Phakic Contact Lens on Correction of Myopia

2022 ◽  
Author(s):  
Mahmoud Ekram ◽  
Ahmed Mohamed Kamal Elshafei ◽  
Asmaa Anwar Mohamed ◽  
Mohamed Farouk Sayed Othman Abdelkader
Keyword(s):  
Visual Acuity ◽  
Anterior Chamber ◽  
Contact Lens ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Case Series ◽  
Care Group ◽  
Case Series Study ◽  
Significant Difference ◽  
The Mean

Abstract Purpose: To evaluate the anatomical effects of implantable phakic contact lens (IPCL) (Care Group, India) on anterior segment and its visual outcomes .Patients and methods: In a prospective interventional case series study, 60 highly myopic eyes of 32 patients were subjected to IPCL implantation in the Ophthalmology Department of Minia University Hospital, Egypt from January 2019 to June 2021. All patients had complete ophthalmic examination and were followed up for 1 year. Pentacam was used for preoperative and postoperative estimation of anterior chamber depth (ACD), anterior chamber angle (ACA), anterior chamber volume (ACV) and IPCL vault in the 1st, 3rd, and 12th months. Assessment of corneal endothelium was done using specular microscope preoperatively and after 12 months. Preoperative and postoperative refraction and visual acuity were measured. Results: There was a statistically significant decrease in ACD, ACA, and ACV. There was no significant difference between preoperative and postoperative mean intraocular pressure (IOP) by the 12th month (P=0.163). The mean preoperative endothelial cell count (ECD) was significantly reduced from 2929.3±248 cells/mm2 to 2737.9±303 cells/mm2 at the 12th month (P<0.001). with a statistically highly significant improvement of mean Log Mar uncorrected visual acuity (UCVA) from 1.48±0.19 preoperatively to 0.46±0.11 by the end of follow up (P<0.001) with insignificant difference between preoperative best corrected visual acuity (BCVA) and postoperative UCVA (P=0.209). In the 12th month, the mean vault was 240±540 μm. No sight threatening complications occurred.Conclusion: Although IPCL induced anatomical changes, it was safe and effective for correction of high myopia.

Sign in / Sign up

Export Citation Format

Share Document