scholarly journals Evaluation of Optical and Radar Based Motion Capturing Technologies for Characterizing Hand Movement in Rheumatoid Arthritis—A Pilot Study

Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1208
Author(s):  
Uday Phutane ◽  
Anna-Maria Liphardt ◽  
Johanna Bräunig ◽  
Johann Penner ◽  
Michael Klebl ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Continuous Wave ◽  
Hand Function ◽  
Objective Assessment ◽  
Hand Movement ◽  
Human Motion ◽  
Limiting Factors ◽  
Human Hand ◽  
Wave Radar ◽  
Patient Reported

In light of the state-of-the-art treatment options for patients with rheumatoid arthritis (RA), a detailed and early quantification and detection of impaired hand function is desirable to allow personalized treatment regiments and amend currently used subjective patient reported outcome measures. This is the motivation to apply and adapt modern measurement technologies to quantify, assess and analyze human hand movement using a marker-based optoelectronic measurement system (OMS), which has been widely used to measure human motion. We complement these recordings with data from markerless (Doppler radar) sensors and data from both sensor technologies are integrated with clinical outcomes of hand function. The technologies are leveraged to identify hand movement characteristics in RA affected patients in comparison to healthy control subjects, while performing functional tests, such as the Moberg-Picking-Up Test. The results presented discuss the experimental framework and present the limiting factors imposed by the use of marker-based measurements on hand function. The comparison of simple finger motion data, collected by the OMS, to data recorded by a simple continuous wave radar suggests that radar is a promising option for the objective assessment of hand function. Overall, the broad scope of integrating two measurement technologies with traditional clinical tests shows promising potential for developing new pathways in understanding of the role of functional outcomes for the RA pathology.

scholarly journals Relationship between patient-reported and objective measurements of hand function in patients with rheumatoid arthritis

Reumatismo ◽  
2016 ◽  
Vol 68 (4) ◽  
pp. 183
Author(s):  
S.M. Günay ◽  
Z. Tuna ◽  
D. Oskay
Keyword(s):  
Rheumatoid Arthritis ◽  
Functional Performance ◽  
Hand Function ◽  
Objective Assessment ◽  
Assessment Tools ◽  
Pinch Strength ◽  
Functional Level ◽  
Hand Functions ◽  
Patient Reported ◽  
Objectively Measured

Rheumatoid arthritis (RA) often results in impairments in upper extremities, especially in the small joints of hand. Involvement of hand brings limitations in activities of daily living. However, it is commonly observed that patient-reported functional status of hand does not always corresponds to their actual physical performance in the clinical setting. The aim of this pilot study is to investigate the relationship between patient self-reported and objectively measured hand functions in patients with RA. Twenty-six patients (51±13 years) with RA diagnosis participated in the study. Hand grip and pinch (lateral, bipod, tripod) strengths were measured and Jebsen Hand Function Test (JHFT) was performed for objective functional performance. Duruöz Hand Index and Beck Depression Inventory - Turkish version were completed by patients. Grip and all three-pinch strength results significantly correlated with Duruöz Hand Index scores (p<0.05). JHFT results except the sentence writing also correlated with the Duruöz scores (p<0.05). Our results showed that self-reported outcome scales might be used for determining functional level of hand in patients with RA in rheumatology practice. Objective quantitative functional tests are the best methods in evaluating functional level of hand, but require valid and reliable equipment with accurate calibration. Therefore, in case of unavailability of objective assessment tools, patient-reported scales may also reflect the real status of hand functions.

scholarly journals Indoor non-rhythmic human motion classification using a frequency-modulated continuous-wave radar

2019 ◽  
Vol 2019 (20) ◽  
pp. 6928-6930
Author(s):  
Yu Zou ◽  
Chuanwei Ding ◽  
Hong Hong ◽  
Changzhi Li ◽  
Xiaohua Zhu
Keyword(s):  
Continuous Wave ◽  
Human Motion ◽  
Motion Classification ◽  
Wave Radar ◽  
Human Motion Classification

Human Hand Movement Analysis Using Principle Component Analysis Classifier

2013 ◽  
Vol 284-287 ◽  
pp. 3126-3130 ◽  
Author(s):  
Ching Yee Yong ◽  
Rubita Sudirman ◽  
Nasrul Humaimi Mahmood ◽  
Kim Mey Chew
Keyword(s):  
Hand Movement ◽  
Arm Movement ◽  
Movement Analysis ◽  
Human Motion ◽  
Human Hand ◽  
Human Arm ◽  
Set Up ◽  
And Behavior ◽  
Adequate Internal Consistency

This study investigates and acts as a trial clinical outcome for human motion and behavior analysis in order to investigate human arm movement during jogging and walking. It was developed to analyze and access the quality of human motion that can be used in hospitals, clinics and human motion researches. It aims to establish how widespread the movement and motion of arm will bring to effect of human in life. An experiment was set up in a laboratory environment with conjunction of analyzing human motion and its behavior. The instruments demonstrate adequate internal consistency of optimum scatter plot in gyroscope and accelerometer for pattern classification. PCA used in this study was successfully differentiate and classify

scholarly journals Plasticity-Inducing TMS Protocols to Investigate Somatosensory Control of Hand Function

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
M. Jacobs ◽  
A. Premji ◽  
A. J. Nelson
Keyword(s):  
Primary Motor Cortex ◽  
Cortical Excitability ◽  
Hand Function ◽  
Hand Movement ◽  
Careful Consideration ◽  
Human Hand ◽  
Motor Behaviour ◽  
Somatosensory Cortices ◽  
Hand Control ◽  
Theta Burst

Hand function depends on sensory feedback to direct an appropriate motor response. There is clear evidence that somatosensory cortices modulate motor behaviour and physiology within primary motor cortex. However, this information is mainly from research in animals and the bridge to human hand control is needed. Emerging evidence in humans supports the notion that somatosensory cortices modulate motor behaviour, physiology and sensory perception. Transcranial magnetic stimulation (TMS) allows for the investigation of primary and higher-order somatosensory cortices and their role in control of hand movement in humans. This review provides a summary of several TMS protocols in the investigation of hand control via the somatosensory cortices. TMS plasticity inducing protocols reviewed include paired associative stimulation, repetitive TMS, theta-burst stimulation as well as other techniques that aim to modulate cortical excitability in sensorimotor cortices. Although the discussed techniques may modulate cortical excitability, careful consideration of experimental design is needed to isolate factors that may interfere with desired results of the plasticity-inducing protocol, specifically events that may lead to metaplasticity within the targeted cortex.

scholarly journals Limiting factors to Boolean remission differ between autoantibody-positive and -negative patients in early rheumatoid arthritis

2020 ◽  
Author(s):  
Serena Bugatti ◽  
Ludovico De Stefano ◽  
Francesca Benaglio ◽  
Garifallia Sakellariou ◽  
Antonio Manzo ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Near Miss ◽  
Limiting Factors ◽  
Treat To Target ◽  
Near Misses ◽  
Early Ra ◽  
Full Remission ◽  
Patient Reported ◽  
Autoantibody Status

Abstract Background: Patients with established rheumatoid arthritis (RA) frequently miss Boolean remission solely because of the patient global assessment of disease activity (PGA) exceeding the cut-off of 1. Here, we investigated the frequency and the limiting variables to disease remission in patients with early RA treated with conventional synthetic disease modifying anti-rheumatic drugs according to a treat-to-target strategy, depending on the autoantibody status. Methods: Data were retrieved from 535 early RA patients (<12 months of symptoms), treatment-naïve at inclusion, with an observation period of 6 to 12 months upon initiation of therapy with methotrexate aimed at the achievement of low disease activity based on the 28-joints disease activity score. Near-remission was defined as any of the 4 core items of Boolean remission exceeding the cut-off of 1 with the remaining 3 all ≤1. Reasons for missing Boolean remission and predictors of near-remission subcategories were analysed in relation to baseline disease variables. Results: After 6 and 12 months from treatment start, near-remission was two-times more frequent than Boolean remission (25.6% and 26.9% at the two time-points). A 28-swollen joint count (SJC28) >1 was responsible for the majority of near-misses (56.2% and 57.6% at 6 and 12 months, respectively), and PGA >1 accounted for approximatively 35% of the cases. None of the variables of disease activity neither patient reported outcomes at baseline could discriminate SJC28 from PGA near-misses. Rather, autoantibody-positivity independently predicted the risk of missing remission because of SJC28 >1 with an adjusted OR [95% CI] of 3.62 [1.89-6.93] at 6 months and 2.36 [1.25-4.47] at 12 months, whilst autoantibody-negativity was an independent predictor of PGA near-miss (adjusted OR [95% CI] 2.71 [1.31-5.64] at 6 months and 6.50 [2.47-17.12] at 12 months). Conclusions: In patients with early RA, Boolean remission is more frequently missed because of persistent swollen joints. However, barriers to full-remission vary in relation to the autoantibody status. Autoantibody-positive patients more commonly experience residual swollen joints, whilst the PGA more frequently impairs the achievement of remission in autoantibody-negative patients. These findings indicate that efforts to target full-remission in early RA may require different treatment strategies according to the autoantibody profile.

Left Hand and Right Hand Throwing Mechanism Patterns Classification

2013 ◽  
Vol 61 (2) ◽  
Author(s):  
Ching Yee Yong ◽  
Rubita Sudirman ◽  
Nasrul Humaimi Mahmood ◽  
Kim Mey Chew
Keyword(s):  
Hand Movement ◽  
Human Motion ◽  
Graphical Form ◽  
Human Hand ◽  
Shoulder Injury ◽  
Hand Motion ◽  
Right Hand ◽  
Left And Right ◽  
2D And 3D

This study investigates and acts as a trial clinical outcome for human hand motion and behaviour analysis. It was analysed and accessed the quality of human motion that can be used to differentiate the left and right hand throwing action patterns and also the effect of throwing distance to shoulder pain. It aims to establish how widespread the quality of life effects of human motion especially hands movement. Gyroscope, accelerometer and compass sensors were used to measure the hand movement for a throwing process. 2D and 3D scatter plotting were proposed to represent data in graphical form. An experiment was set up in a laboratory environment with conjunction of analysing human motion. The instruments demonstrate 2D and 3D scatter plot enable distinguish left and right hand throwing action patterns significantly. Distribution of gyroscope data shows that a throwing mechanism for a greater distance may bring greater probability of shoulder injury.

scholarly journals AB0188 DO PATIENT-REPORTED OUTCOMES IN RHEUMATOID ARTHRITIS REFLECT DISEASE ACTIVITY?

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1118.2-1119
Author(s):  
K. Ben Abdelghani ◽  
H. Boussaa ◽  
S. Miladi ◽  
M. Sellami ◽  
L. Souabni ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Patient Reported Outcomes ◽  
Morning Stiffness ◽  
Objective Assessment ◽  
Disease State ◽  
Spontaneous Pain ◽  
Patient Reported ◽  
The Mean ◽  
The Impact

Background:Patient-reported outcomes (PROs) reflect the patient’s perspective and are used in rheumatoid arthritis (RA) routine clinical practice. However, PROs may be associated with other aspects of health, such as psychological distress or comorbidities, which leads to situations of discordance with objective RA assessments.Objectives:The aim of this study was to determine whether PROs were associated with objective assessment of disease activity.Methods:We conducted a cross-sectional study including patients with RA (ACR/EULAR 2010). Demographic data were collected. The following PROs were assessed: number of nocturnal awakenings, morning stiffness duration, estimation of spontaneous pain and fatigue by Visual Analog Scale (VAS), and global patient assessment (GPA). In addition, patients rated their current satisfaction with their disease state according to the Austrian school mark system (PATSAT: 1=excellent, 2=good, 3=average, 4=moderate (fair), 5=unsatisfactory). Disease activity was assessed using the 28-joint disease activity score with erythrocyte sedimentation rate (DAS28 ESR) and C reactive protein (DAS28 CRP). We used Cohen’s kappa (κ) to determine the agreement between PATSAT and DAS28 ESR. The κ result was interpreted as follows: values ≤ 0 as indicating no agreement and 0.01–0.20 as none to slight, 0.21–0.40 as fair, 0.41– 0.60 as moderate, 0.61–0.80 as substantial, and 0.81–1.00 as almost perfect agreement. A p-value inferior to 0.05 was considered significant.Results:We included 54 patients (45 women and nine men) with a mean age of 55±11 years old [23-69]. The mean disease duration was 9.9±5.9 years [0-20]. The mean number of nocturnal awakenings was 1.1 [0-4] and the mean morning stiffness duration was 25.1 minutes [0-120]. The mean GPA was 5.3±2.2 cm [0-10]. The mean pain VAS was 5.4±2.2 cm [0-10] and the mean fatigue VAS was 4±2.5 cm [0-8]. None of the patients described his disease state as ‘excellent’. It was considered ‘good’ in 23.1% of cases, ‘average’ in 36.5% of cases, and ‘moderate’ to ‘unsatisfactory’ in 40.4% of cases.The mean ESR and CRP were 46.3±29.3 mm [5-120] and 15.8 mg/l [0.6-100] respectively. The mean DAS28 ESR was 4.68±1.35 [1.50-7.16] and the mean DAS28 CRP was 3.9±1.1 [1.02-6.05].A significant positive correlation was noted between both DAS28 ESR and DAS28 CRP and, number of nocturnal awakenings (r=0.385, p=0.013 and r=0.448, p=0.002), morning stiffness duration (r=0.495, p=0.001 and r=0.617, p<0.001), GPA (r=0.485, p<0.001 and r=0.530, p<0.001), and pain VAS (r=0.594, p<0.001 and r=0.598, p<0.001). No correlation was found between the two scores and fatigue VAS.No significant agreement was noted between PATSAT and DAS28 ESR (κ=0.077, p=0.478).Conclusion:PROs showed moderate to strong correlation with disease activity scores. The timely and effective use of PROs could encourage physicians to focus more on the impact of RA on patients and how patients are feeling. This in turn would facilitate shared decision making between patients and physicians.Disclosure of Interests:None declared

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